CN101439054A - Packed Chinese medicine powder decoction pieces and preparing technique thereof - Google Patents

Packed Chinese medicine powder decoction pieces and preparing technique thereof Download PDF

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Publication number
CN101439054A
CN101439054A CNA2007101932427A CN200710193242A CN101439054A CN 101439054 A CN101439054 A CN 101439054A CN A2007101932427 A CNA2007101932427 A CN A2007101932427A CN 200710193242 A CN200710193242 A CN 200710193242A CN 101439054 A CN101439054 A CN 101439054A
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China
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powder
decoction pieces
chinese medicine
chinese medicinal
traditional chinese
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CNA2007101932427A
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Chinese (zh)
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曹生沅
杨爱萍
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Individual
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Abstract

The invention relates to bagged traditional Chinese medicine powder decoction pieces and the preparation method thereof. Different traditional Chinese medicine materials are selected as raw materials according to national standards. The traditional Chinese medicine materials then undergo quality appraisal, and the bagged traditional Chinese medicine powder decoction pieces are obtained after the procedures of cleansing the medicinal materials, softening and cutting the medicinal materials, processing decoction pieces, crushing the decoction pieces, drying powder, packaging the powder in terms of grams, sterilizing the packaged powder, testing finished products, and the like. After the crushing of the traditional Chinese medicine decoction pieces, the powder has such granularity that the powder can all pass through 10-mesh sieve pores, less than 20 percent of powder which can pass through 50-mesh sieve pores is mixed together, and the maximum granularity of the powder is no more than 2 mm. The traditional Chinese medicine powder decoction pieces have small granularity, is favorable for the leaching or dissolving-out of effective components of the medicinal powder and can achieve the effects of reducing medicinal material consumption and improving the effectiveness of the medicine.

Description

A kind of packed Chinese medicinal powder decoction pieces and production technology thereof
Technical field
The present invention relates to technical field of Chinese medicines, particularly a kind of packed prepared slices of Chinese crude drugs and processing method thereof.
Background technology
The existing prepared slices of Chinese crude drugs have following several usually: 1, Chinese medicine solid decoction pieces.Generally use in medical institutions and pharmacy, this type of decoction pieces is because there are more problem in traditional habit and historical reasons aspect the quality health.2, single medicinal material granule decoction pieces." the medicine quantitatively packaged and production technology of unit " (Granted publication CN1090472C) disclosed single medicinal material granule decoction pieces and production technology as State Intellectual Property Office's JIUYUE in 2002 bulletin on the 11st, this decoction pieces particle diameter is less than or equal to 5mm (being equivalent to Semen phaseoli radiati grain size), fine powder less than 1mm is less than or equal to 10%, accounts for more than 60% greater than the particle diameter of 3mm.If by this processing, there are problems: in the processing cutting, just be difficult to realize that particle diameter greater than 3mm, is no more than 5mm as medicines such as the mealiness in the Chinese medicine, flower class, leaf class, fruit class, animal class, mineral substances, be less than or equal to 10% standard less than the fine powder of 1mm; Decoction pieces processing technique elder generation cutting granule in this Patent right requirement 2, concoct the back.As technological operation according to this, how to carry out process of preparing Chinese medicine such as processed with honey, parched with bran, rice stir-fry, parching with earth, stir-baking with sand, steaming and decocting back separating of medicines and adjuvant less than the medicine grain below the 3mm? this patent is that packing is divided into 2g, 3g, 5g, 6g, 9g, 10g, seven kinds of specifications of 15g, there are packed, bottled two kinds, packedly quantitatively pack with the non-toxic plastic bag single.Even nontoxic with plastic bag packaging, because the plastic bag material is a polyethylene, be used for food or drug packaging, be disadvantageous to health.Using another disadvantage of plastic bag packaging is non-degradable, is conspicuous to the hazardness of environment.Simultaneously, the steam that produces with the microwave sterilizating heating also can't disengage, and moldy metamorphism easily lumps.Moreover being packaged in the practical operation of seven kinds of specifications is too loaded down with trivial details, and quantitative specification of its stepping and clinical practice are used and be not complementary.
Summary of the invention
The objective of the invention is the weak point that exists at the existing prepared slices of Chinese crude drugs, provide that a kind of quality safety is reliable, hygienic practice, fried convenience, can fully reach the packed powder prepared slices of Chinese crude drugs of medicinal effects.
The object of the present invention is achieved like this.This packed Chinese medicinal powder decoction pieces is various Chinese crude drug to be carried out crude drug by national standard select, quality is identified, is made through operations such as clean pharmacy material, softening cutting, process of preparing, pulverizing, powder for drying, decigram packing, sterilization, product inspections.Clean pharmacy material, softening cutting, process of preparing operation are to remove the dis-medicinal part of Chinese crude drug and silt, impurity, the product that go mouldy, the product etc. of damaging by worms, choose the medicinal part of Chinese crude drug, by softening cutting, with medical material according to selecting different method for treating water for use in differing texture, season, it is softening to carry out quality, be cut into the thin slice of 2mm then with microtome, carry out standard again and concoct; Pulverizing process is that the powder degree after this Chinese medicinal powder decoction pieces is pulverized all can pass through 10 mesh sieve holes, be mixed with and can be no more than 20% by the powder in 50 mesh sieve holes, powder directly maximum be no more than 2mm; Powder medicine after powder for drying will be pulverized is used method for microwave drying, and general medicated powder temperature is no more than 80 ℃ and is advisable, and the medicated powder temperature that contains fragrant volatile ingredient is no more than 50 ℃, and water content is controlled in 7%.The decigram packaging process is that packed Chinese medicinal powder decoction pieces is restrained the fractional pack that is packaged into four kinds of various dose by 1 gram, 2 grams, 5 grams, 10, and the filter paper material is adopted in the packaging bag of Chinese medicinal powder decoction pieces.In carrying out filter paper decigram packaging process, adopt following extra package processing mode at the different situations of Chinese medicinal powder decoction pieces: commute is infested, easily mouldy, easy to change, easy differentiation, easily melt, easy deliquescence, easy remollescent medicated powder add the compound fractional pack of paraffin paper with filter paper; The medicated powder of commute bellding, easy flatus flavor adds the compound fractional pack of cellophane with filter paper; To valuable medicine and hypertoxic medicine, the minimum dose packing that can be distributed into daily dose or once measure.Sterilization be adopt microwave technology or 60The Co-γShe Xianmiejun.
The present invention has following effect: 1, according to diffusion law as can be known, the amount of diffusate and the particle radii of diffusate are inversely proportional to, and the powder decoction pieces particle radius is more little, and the amount of leaching is just many more.Because this Chinese medicinal powder decoction pieces powder degree is little, helps the leaching or the stripping of medicated powder effective ingredient, can reach and reduce the medical material consumption, improve the effect of drug effect; Adopt powder particle to fry in shallow oil soup, can save 1/2nd to 2/3rds of medical material, and can reach the therapeutic effect of former prescription full dose.2, the present invention adopts filter paper packaging material, environment-friendly degradable; Packed powder decoction pieces of filter paper and water got final product with boiling in 7-15 minutes, Non-burnt pot, need not strain medicine, taking convenience.3, this Chinese medicinal powder decoction pieces divides 1g, 2g, four kinds of specifications of 5g, 10g, is convenient to clinical prescription at random.4, this packed Chinese medicinal powder decoction pieces adopts 60The Co-γShe Xianmiejun does not destroy the medicated powder profile, the medicine temperature that do not raise, and penetration power is strong, and not toxigenicity material, and sterilization effect is good.
The specific embodiment
The specific embodiment of the present invention is as follows: be example with the Radix Astragali
Prescription name: the Radix Astragali (Radix Astragali), Radix Astragali Preparata (the sweet Radix Astragali)
One, crude drug is selected: the genuine Radix Astragali of selecting the Inner Mongol to produce, and medicinal part is exsiccant, spring and autumn is excavated, and is the best in quality with what excavate autumn.
Two, quality is identified: get raw material, according to country's version " pharmacopeia " in 2005 and promulgated by the ministries or commissions of the Central Government, provincial standard, to the Radix Astragali originate, character, micro-, physical and chemical identification, detect the harmful substance of the Radix Astragali simultaneously: 1, persticide residue is no more than 0.2mg for every kilogram; 2, flavacin is no more than 10 μ g for every kilogram; 3, heavy metal is every kilogram: lead is no more than 5mg, and arsenic is no more than 3mg, and hydrargyrum is no more than 0.2mg, and cadmium is no more than 0.3mg.Detecting up to standard is qualified medical material.
Three, clean pharmacy material: with the Radix Astragali of accreditation, remove fibrous root, reed head, the product that go mouldy, the product of damaging by worms, impurity etc., put into tumbling-box type medicine-washing machine and clean, remove silt.Prescription: the limit of impurities≤2% is qualified.
Four, softening cutting: with clean Radix Astragali (processed), choose the medicinal part of Chinese medicine, medical material according to differing texture, season choosing different method for treating water, is put into vacuum vapour phase displaced type medicine processing device and softened processing before cutting.Be cut into the thin slice of 2mm then with microtome.Prescription: softening inflection is not easily broken, and humidity is inside and outside consistent, no hard-core; The thin slice uniformity of cutting is qualified.
Five, process of preparing: with the Radix Astragali decoction pieces of cutting, according to clinical demand difference, divide two classes: a class is a Radix Astragali, does not need to concoct; Another kind of is Radix Astragali Preparata, and every 100kg Radix Astragali is used Mel 25kg.Earlier Mel is put a pot internal heating boiling, scumming impurity when playing the flake bubble, adds certain amount of boiling water and dilutes, again astragalus mongholicus tablet is poured into and stirred, in vexed slightly a moment, put into cylinder type medicine roasting machine, fry to buff with slow fire, the degree of being with tack-free, taking out and spreading the cold of drying in the air out is that processed with honey is qualified.
Six, pulverize:, put into Chinese medicine grinder respectively and pulverize the Radix Astragali Preparata after the Radix Astragali after the cutting and the process of preparing Chinese medicine.The powder degree all can pass through 10 mesh sieve holes, is mixed with and can be no more than 20% by the powder in 50 mesh sieve holes, and powder footpath is maximum is no more than 2mm.Prescription: even, the pure powder of powder is qualified.
Seven, powder for drying: the Radix Astragali powder after will pulverizing, carry out the Radix Astragali powder drying with tunnel microwave medicinal material drying machine, general temperature is no more than 80 ℃ and is advisable.Packing again after waiting to cool is in case the non-return tide goes mouldy.Prescription: water content should be controlled in 7%, and it is qualified that medicated powder should keep color, gas that the Radix Astragali should have originally, flavor does not become.
Eight, decigram packing: with dried Radix Astragali powder, use special filter paper,, carry out packing, be packaged into the packed decoction pieces of Radix Astragali powder fractional pack with full-automatic packing machine by 1 gram, 2 grams, 5 grams, four kinds of packed specifications of 10 grams.
Nine, sterilization: with the packed decoction pieces of packaged Radix Astragali powder, adopt microwave technology or 60Co-gamma-rays radiation Pesticidal and sterilizing technology is sterilized, and the packed decoction pieces hygiology of the Radix Astragali powder after sterilization prescription: pathogenic bacterium: every gram must not detect escherichia coli; Total number of bacteria is no more than 10000; Mycete is no more than 100; Must not detect demodicid mite alive and the demodicid mite ovum of living.
Ten, product inspection: detect item by item by national correlated quality standard.
The inventive method can be used for 700 kinds of Chinese herbal medicine commonly used such as Radix Angelicae Sinensis, Flos Lonicerae, Cortex Phellodendri, Semen Cassiae, the Radix Paeoniae Alba, Cortex Magnoliae Officinalis, Poria, Gypsum Fibrosum.

Claims (4)

1, a kind of packed Chinese medicinal powder decoction pieces is characterized in that the powder degree of this Chinese medicinal powder decoction pieces all can pass through 10 mesh sieve holes, is mixed with and can be no more than 20% by the powder in 50 mesh sieve holes, and powder footpath is maximum is no more than 2mm; The filter paper material is adopted in the packaging bag of Chinese medicinal powder decoction pieces.
2, the production technology of a kind of packed Chinese medicinal powder decoction pieces according to claim 1, this packed Chinese medicinal powder decoction pieces production technology is that Chinese crude drug is carried out Quality Identification by national standard, clean through cleaning, processing is concocted, pulverize, powder for drying, sterilization, product inspection, at last by 1 gram, 2 grams, 5 grams, 10 grams are packaged into the fractional pack of four kinds of various dose, it is characterized in that described cleaning cleans, it is dis-medicinal part and the silt of removing Chinese crude drug that processing is concocted, impurity, product go mouldy, the product etc. of damaging by worms, choose the medicinal part of Chinese crude drug, by softening cutting, with medical material according to differing texture, select different method for treating water season for use, it is softening to carry out quality, be cut into the thin slice of 2mm then with microtome, concoct again, pulverize, dry; Sterilization be adopt microwave technology or 60The Co-γShe Xianmiejun.
3, according to claim 1 and 2 described a kind of packed Chinese medicinal powder decoction pieces and production technologies thereof, it is characterized in that in carrying out filter paper decigram packaging process, adopt following extra package processing mode at the different situations of Chinese medicinal powder decoction pieces: commute is infested, easily mouldy, easy to change, easy differentiation, easily melt, easy deliquescence, easy remollescent medicated powder add the compound fractional pack of paraffin paper with filter paper; The medicated powder of commute bellding, easy flatus flavor adds the compound fractional pack of cellophane with filter paper; To valuable medicine and hypertoxic medicine, the minimum dose packing that can be distributed into daily dose or once measure.
4, according to claim 1 and 2 described a kind of packed Chinese medicinal powder decoction pieces and production technologies thereof, it is characterized in that powder for drying is with the powder medicine after pulverizing, use method for microwave drying, general medicated powder temperature is no more than 80 ℃ and is advisable, the medicated powder temperature that contains fragrant volatile ingredient is no more than 50 ℃, and water content is controlled in 7%.
CNA2007101932427A 2007-11-25 2007-11-25 Packed Chinese medicine powder decoction pieces and preparing technique thereof Pending CN101439054A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102228468A (en) * 2011-06-29 2011-11-02 广州市药材公司中药饮片厂 Preparation method for granular Chinese herbal pieces
CN104289156A (en) * 2014-10-27 2015-01-21 甘肃中医学院 Method for softening traditional Chinese medicinal material before slicing
CN106706634A (en) * 2016-05-21 2017-05-24 广州今典精方药业有限公司 Quality standard and preparation process of qualitative and quantitative Chinese herbal astragali radix decoction slice
CN113009047A (en) * 2021-04-12 2021-06-22 湖北一正药业股份有限公司 Quality management and supervision method for traditional Chinese medicine compound decoction pieces

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102228468A (en) * 2011-06-29 2011-11-02 广州市药材公司中药饮片厂 Preparation method for granular Chinese herbal pieces
CN104289156A (en) * 2014-10-27 2015-01-21 甘肃中医学院 Method for softening traditional Chinese medicinal material before slicing
CN106706634A (en) * 2016-05-21 2017-05-24 广州今典精方药业有限公司 Quality standard and preparation process of qualitative and quantitative Chinese herbal astragali radix decoction slice
CN113009047A (en) * 2021-04-12 2021-06-22 湖北一正药业股份有限公司 Quality management and supervision method for traditional Chinese medicine compound decoction pieces

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Open date: 20090527