CN103690596B - Compound ground hemlock tea buccal tablet and preparation process thereof - Google Patents
Compound ground hemlock tea buccal tablet and preparation process thereof Download PDFInfo
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- CN103690596B CN103690596B CN201310670337.9A CN201310670337A CN103690596B CN 103690596 B CN103690596 B CN 103690596B CN 201310670337 A CN201310670337 A CN 201310670337A CN 103690596 B CN103690596 B CN 103690596B
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- 238000002360 preparation method Methods 0.000 title claims abstract description 14
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- 241000233779 Cyclocarya paliurus Species 0.000 claims abstract description 33
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- 239000000284 extract Substances 0.000 claims abstract description 26
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- 239000008101 lactose Substances 0.000 claims abstract description 7
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- 235000019154 vitamin C Nutrition 0.000 claims abstract description 7
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- 241001122767 Theaceae Species 0.000 claims description 45
- 235000016408 Podocarpus macrophyllus Nutrition 0.000 claims description 21
- 244000162450 Taxus cuspidata Species 0.000 claims description 21
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 10
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- 239000000203 mixture Substances 0.000 claims description 7
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- 240000004670 Glycyrrhiza echinata Species 0.000 claims description 2
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 claims description 2
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims description 2
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- 229920001030 Polyethylene Glycol 4000 Polymers 0.000 claims description 2
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a compound ground hemlock tea buccal tablet and a preparation process thereof. The compound ground hemlock tea buccal tablet comprises 5 parts of ground hemlock tea water extract dry product, 10 parts of cyclocarya paliurus tea water extract dry product, 3 parts of liquorice root water extract dry product, 2 parts of menthol, 1 part of vitamin C, 50 parts of lactose, 20 parts of dextrin, 5 parts of polyvinylpyrrolidone and 4 parts of polyethylene glycol-6000. The preparation process comprises the following steps: crushing main materials (ground hemlock tea, cyclocarya paliurus tea and liquorice root), ultrasonically breaking walls, extracting with water at a temperature of below 85 DEG C, concentrating, drying to prepare water extract dry products; compounding the main materials and the auxiliary materials; uniformly mixing; crushing, screening with a 40mu sieve; drying; tabletting and forming by using a tabletting machine; drying, granulating; sterilizing; checking; packaging. The compound ground hemlock tea buccal tablet has the characteristics of good mouth feel, developmental nutrition, and convenience in use and carrying, and is easy to absorb, and has the effects of resisting fatigue and oxidation, and improving the body immunity.
Description
Technical field
The invention belongs to the field of Chinese medicines, it is related to a kind of compound ground hemlock tea buccal tablet and its preparation technology.
Background technology:
Tea of Japanese yew used by product of the present invention was by raw Taxus mairei trees top tender leaf processing in tame 3~5 years.
Taxus mairei belongs to taxaceae plant, arbor.Ramulus et folium taxi cuspidatae can be used as medicine with stem, branch, leaf, root, has inducing diuresis to remove edema, treatment kidney
Disease of ZANG-organs, diabetes, nephritis edema, dysuria, gonorrhea etc.;Can the kidney warming stimulate the menstrual flow, effectively treatment menoxenia, postnatal blood stasis, bitterly
Through etc..Contain the multiple nutritional components such as flavone, polysaccharide, polyphenol, diterpenoids compound in analysis display tea of Japanese yew, have anti-tired
Labor, effect of raising immunity of organisms.
Cyclocarya paliurus tea used by product of the present invention is processed by Cyclocarya paliurus Iljinskaja early spring bud-leaf.Cyclocarya juglandaceae plant, fallen leaves
Arbor.Ancient prescription is recorded leaf of Cyclocarya paliurus Iljinskaja and is had heat clearing away and quenches one's thirst the effect of removing toxic substances, and tcm clinical practice is used for treating diabetes, can substantially reduce blood
Sugar, fat reducing fat and glucose in urine.Analysis display cyclocarya paliurus tea is rich in abundant containing polysaccharide, triterpene, saponin, multiple organic nutrition such as flavone
Composition, can active balance human body carbohydrate metabolism, there is enhancing body immunity, antioxidation, anti-ageing health preserving effect of waiting for a long time.
The development of science and technology, has been capable of the intensive processing of Chinese crude drug so as to be more prone to benefit masses.At present,
Yew leaf, leaf of Cyclocarya paliurus Iljinskaja Related product have been sold and reported in market, but there are no the report of the compound buccal tablet comprising 2 kinds of compositions
Road.
Based on background above, the present inventor carries out intensive processing to Ramulus et folium taxi cuspidatae Folium Camelliae sinensis, Cyclocarya paliurus Iljinskaja Folium Camelliae sinensis, by lot of experiments and
Research, a kind of compound ground hemlock tea buccal tablet is prepared in screening, and product has the characteristics that to be easy to absorb, using easy to carry, has
Resisting fatigue, antioxidation, heat clearing away, the effect of raising immunity of organisms.The present invention opens for expansion Ramulus et folium taxi cuspidatae Folium Camelliae sinensis, Cyclocarya paliurus Iljinskaja Folium Camelliae sinensis
Send out and utilize, improve and realize its economic worth, there is higher realistic meaning.
Content of the invention:
The present invention proposes a kind of compound ground hemlock tea buccal tablet and its preparation technology.
A kind of compound ground hemlock tea buccal tablet of the present invention, including major ingredient (5 parts of tea of Japanese yew water extract dry product, blue or green money
10 parts of Sibiraea angustata water extract dry product, 3 parts of Radix Glycyrrhizae water extract dry product);Adjuvant (2 parts of Mentholum, 1 part of vitamin C, 50 parts of Lactose, paste
20 parts of essence, 5 parts of Polyvinylpyrrolidone, 4 parts of PEG-4000).
Major ingredient is characterised by by tea of Japanese yew water extraction extractum dry product, cyclocarya paliurus tea water extraction extractum dry product, Radix Glycyrrhizae water extraction
Extractum cream forms for main component compound compatibility, and product improves the taste of Ramulus et folium taxi cuspidatae tea product, containing plurality of active ingredients, energy
More preferably play its effect, improve the using value of tea of Japanese yew.In raw material, tea of Japanese yew is the natural Taxus mairei 3 of artificial growth
Raw top tender leaf processing in~5 years, Cyclocarya paliurus Iljinskaja is natural Cyclocarya paliurus Iljinskaja tender leaf processing.Tea of Japanese yew, cyclocarya paliurus tea, the water extract of Radix Glycyrrhizae
Dry product adopts supersonic wave wall breaking technology, extracts preparation, realize filling of tea of Japanese yew and cyclocarya paliurus tea effective ingredient at less than 85 DEG C
Divide dissolution, improve bioavailability.
The preparation technology of compound ground hemlock tea buccal tablet of the present invention is as follows:
(1) take tea of Japanese yew, cyclocarya paliurus tea, licorice raw material, pulverized with high speed disintegrator, cross 40 mesh sieves;Tea of Japanese yew, Cyclocarya paliurus Iljinskaja
Tea, the powder of Radix Glycyrrhizae, respectively with the water retting of 2 times of weight, supersonic wave wall breaking 20min;It is separately added into 8 times of weight water again,
Less than 85 DEG C are extracted, and filter, extracting solution concentrating under reduced pressure, negative pressure drying, obtain the water extraction of tea of Japanese yew, cyclocarya paliurus tea, Radix Glycyrrhizae
Take thing dry product.
(2) get all the main ingredient ready by aforementioned;Mix homogeneously, is suitably added concentration 90% edible ethanol and assists batch mixing;It is dried;Grind
Pulverizing is broken, crosses 40 mesh sieves;Shaped with tabletting machine, weigh about 500mg/ every containing blade;It is dried, granulate;Sterilization;Inspection;Bag
Dress.
Product of the present invention has the characteristics that to be easy to absorb, using easy to carry, there is resisting fatigue, antioxidation, heat clearing away, raising
The effect of immunity of organisms.
Specific embodiment:
It is described in detail with reference to embodiments:
Embodiment 1:
Tea of Japanese yew, cyclocarya paliurus tea, the preparation of Radix Glycyrrhizae water extract dry product
Weigh Ramulus et folium taxi cuspidatae Folium Camelliae sinensis, Cyclocarya paliurus Iljinskaja Folium Camelliae sinensis, each 100g of Radix Glycyrrhizae respectively, pulverize, cross 40 mesh sieves;Use the water of 200mL respectively
Dipping powder, puts into supersonic generator, supersonic wave wall breaking 20min;It is separately added into and uses 800mL water, carry in 80~85 DEG C of heat
Take 6 hours;Vacuum filtration;Filtrate is in 40~50 DEG C of concentrating under reduced pressure;Concentrated solution is dried under 0.05Mpa negative pressure, prepares Ramulus et folium taxi cuspidatae
Tea, cyclocarya paliurus tea, Radix Glycyrrhizae water extract dry product.
Embodiment 2:
Tea of Japanese yew, cyclocarya paliurus tea, the preparation of Radix Glycyrrhizae water extract dry product
Weigh Ramulus et folium taxi cuspidatae Folium Camelliae sinensis, Cyclocarya paliurus Iljinskaja Folium Camelliae sinensis, each 80g of Radix Glycyrrhizae respectively, pulverize, cross 40 mesh sieves;Use the water logging of 160mL respectively
Stain powder, puts into supersonic generator, supersonic wave wall breaking 20min;It is separately added into the water of 960mL again, steep in 20~30 DEG C of mercerations
24 hours;Vacuum filtration;Filtrate is in 40~50 DEG C of concentrating under reduced pressure;Concentrated solution is dried under 0.05Mpa negative pressure, prepares Ramulus et folium taxi cuspidatae
Tea, cyclocarya paliurus tea, Radix Glycyrrhizae water extract dry product.
Embodiment 3:
The preparation of compound ground hemlock tea buccal tablet
By weight, 5 parts of tea of Japanese yew water extract dry product, 8 parts of cyclocarya paliurus tea extract dry product, Radix Glycyrrhizae water extract are weighed
5 parts of dry product, 2 parts of Mentholum, 1 part of vitamin C, 50 parts of Lactose, 20 parts of dextrin, 5 parts of Polyvinylpyrrolidone, Polyethylene Glycol-
60004 parts.Mix homogeneously, mixed process can suitably Jia 5~and 90% edible ethanol of 10 parts of weights assists batch mixing.Mixed material is 50
DEG C infrared forced air drying of baking oven 3 hours.Mill pulverizing batch mixing, cross 40 mesh sieves.Become round using tabletting machine, buccal tablet diameter
8mm, piece weighs about 0.5mg/ every.Buccal tablet air-dries, it is desirable to buccal tablet smooth surface, size is homogeneous for granulate.Qualified products are in purple
Sterilize under outer light 10min, packs.
Embodiment 4:
The preparation of compound ground hemlock tea buccal tablet
By weight, 5 parts of tea of Japanese yew water extract dry product, 10 parts of cyclocarya paliurus tea extract dry product, Radix Glycyrrhizae water extraction are weighed
3 parts of thing dry product, 2 parts of Mentholum, 1 part of vitamin C, 50 parts of Lactose, 20 parts of dextrin, Polyvinylpyrrolidone, Polyethylene Glycol-
60004 parts.Mix homogeneously, mixed process can suitably Jia 5~and 90% edible ethanol of 10 parts of weights assists batch mixing.Mixed material is 50
DEG C infrared forced air drying of baking oven 3 hours.Mill pulverizing batch mixing, cross 40 mesh sieves.Become round using tabletting machine, buccal tablet diameter
8mm, piece weighs about 0.5mg/ every.Buccal tablet air-dries, it is desirable to mouth 3 buccal tablet smooth surface, size is homogeneous for granulate.Qualified products exist
Sterilize under ultraviolet light 10min, packs.
Embodiment 5:
By weight, 7 parts of tea of Japanese yew water extract dry product, 8 parts of cyclocarya paliurus tea extract dry product, Radix Glycyrrhizae water extract are weighed
3 parts of dry product, 2 parts of Mentholum, 1 part of vitamin C, 50 parts of Lactose, 20 parts of dextrin, 5 parts of Polyvinylpyrrolidone, Polyethylene Glycol-
60004 parts.Mix homogeneously, mixed process can suitably Jia 5~10 parts in 90% edible ethanol assist batch mixing.Mixed material is 50
DEG C infrared forced air drying of baking oven 3 hours.Pulverize dispensing, cross 40 mesh sieves.Become round using tabletting machine, buccal tablet diameter 8mm,
Piece weighs about 0.5mg/ every.Buccal tablet air-dries, it is desirable to buccal tablet smooth surface, size is homogeneous for granulate.Qualified products are in ultraviolet light
Lower sterilization 10min, packs.
Claims (1)
1. a kind of compound ground hemlock tea buccal tablet, is characterized in that what described buccal tablet was made up of the raw material of following weight proportioning, Ramulus et folium taxi cuspidatae
Tea carries 5 parts of extractum dry product;10 parts of cyclocarya paliurus tea water extraction extractum dry product;3 parts of Radix Glycyrrhizae water extraction extractum dry product;Mentholum 2
Part;Vitamin C, 1 part;50 parts of Lactose;20 parts of dextrin;5 parts of Polyvinylpyrrolidone;PEG-4000,4 parts;Described raw material
Tea of Japanese yew is raw Taxus mairei trees top tender leaf processing in 3~5 years of artificial growth, and cyclocarya paliurus tea is the natural Cyclocarya paliurus Iljinskaja early spring
Bud-leaf is processed;Described tea of Japanese yew, cyclocarya paliurus tea, the extract of Radix Glycyrrhizae are using supersonic wave wall breaking technology, carry at less than 85 DEG C
Take preparation;
The preparation technology of described compound ground hemlock tea buccal tablet is as follows:
(1) take tea of Japanese yew, cyclocarya paliurus tea, licorice raw material, pulverized with high speed disintegrator, cross 40 mesh sieves;Tea of Japanese yew, cyclocarya paliurus tea,
The powder of Radix Glycyrrhizae, respectively with the water retting of 2 times of weight, supersonic wave wall breaking 20min;Again respectively add 8 times of weight water, 85 DEG C with
Under extracted, concentrating under reduced pressure, negative pressure drying, prepare corresponding water extract dry product;
(2) press 5 parts of tea of Japanese yew water extract dry product, 10 parts of cyclocarya paliurus tea water extract dry product, 3 parts of Radix Glycyrrhizae water extract dry product is thin
2 parts of lotus brain, 1 part of vitamin C, 50 parts of Lactose, 20 parts of dextrin, 5 parts of Polyvinylpyrrolidone, 4 parts of PEG-4000, carry out
Get the raw materials ready;
(3) above-mentioned raw materials mix homogeneously, is suitably added the edible ethanol that concentration is 90% and assists batch mixing;
(4) it is dried, pulverizing of milling, cross 40 mesh sieves;
(5) tabletting machine shapes;
(6) dry, granulate;
(7) ultraviolet-sterilization 10min;
(8) pack.
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