CN101415327A - Method of controlling phytopathogenic diseases on turfgrass - Google Patents
Method of controlling phytopathogenic diseases on turfgrass Download PDFInfo
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- CN101415327A CN101415327A CNA2007800125433A CN200780012543A CN101415327A CN 101415327 A CN101415327 A CN 101415327A CN A2007800125433 A CNA2007800125433 A CN A2007800125433A CN 200780012543 A CN200780012543 A CN 200780012543A CN 101415327 A CN101415327 A CN 101415327A
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Abstract
A method of controlling phytopathogenic diseases on turfgrass or on seeds thereof, comprises applying to the turfgrass, the locus thereof or seeds thereof a composition, that, in addition to formulation adjuvants, comprises a fungicidally effective amount of at least one compound of formula (I), wherein A is formula (A1) or formula (A2); or a tautomer of such a compound.
Description
The present invention relates to prevent and treat the method that causes phytopathy venereal disease evil of turfgrass.
Be disclosed in JP-2004-123587 by the method that causes phytopathy venereal disease evil of using substituted thiophene derivant control turfgrass.A kind of described substituted thiophene derivant is pyrazolecarboxamide compound N-[2-(1, the 3-dimethylbutyl)-3-thienyl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide, also is known as pyrrole metsulfovax (Penthiopyrad).
From WO 04/035589 and WO 04/058723 as can be known some heterocycle-formamide have the anti-biologically active that causes plant characteristic of disease fungi.WO 04/035589 and WO 04/058723 disclose the purposes of the disease in described heterocycle-formamide control or prevention crop plants such as wheat, apple, barley, grape, tomato and the rice.Do not mention the purposes of the disease of described heterocycle-formamide control turfgrass at WO 04/035589 or WO 04/058723.
High-quality, healthy lawn is indispensable to for example golf industry.So, thereby exist in this area improving the turfgrass quality and protecting turfgrass to cause the needs that phytopathy venereal disease evil provides the new method on high-quality, healthy lawn with antagonism.
Surprising discovery, be selected from 3-difluoromethyl-1-methyl isophthalic acid H-pyrazoles-4-carboxylic acid (9-isopropyl-1,2,3,4-tetrahydrochysene-1,4-endo-methylene group-naphthalene-5-yl)-pyrazolecarboxamide of acid amides (IA) and 3-difluoromethyl-1-methyl isophthalic acid H-pyrazoles-4-carboxylic acid [4 '-(3,3-dimethyl-Ding-1-alkynyl)-xenyl-2-yl]-acid amides (IB) suits to the phytopathy venereal disease evil that causes of control turfgrass.
According to the present invention, provide on the control turfgrass or the method that causes phytopathy venereal disease evil on its seed, it comprises to this turfgrass, its location or its seed uses composition, and said composition comprises at least a formula I compound of antifungal effective dose except that formulation auxiliary agents
Wherein A is
Or the dynamic isomer of this compound.
The inventive method is suitable especially to improving the turfgrass quality.So another aspect of the present invention is to improve the method for turfgrass quality, it comprises to this turfgrass, its location or its seed uses composition, and said composition includes the formula I compound of imitating the amount that increases the turfgrass quality except that formulation auxiliary agents
Wherein A is
Or the dynamic isomer of this compound.
Statement turfgrass used herein " quality " is intended to comprise the function quality of the vision quality and the turfgrass of turfgrass.
" vision quality " of turfgrass relates to visual appearance, for example density (per unit area terrestrial stem number), the uniformity (homogeneity of texture such as width of blade for example, its can as red fescue in be close grain or in as the alta fascue grass, be open grain), color or smoothness (it influences for example playability of golf course).
" the function quality " of turfgrass relates to, for example, hardness (the lawn blade of grass is to the resistance of compressing and relate to the anti-damageability on lawn), elasticity (pressure removes the tendentiousness of back turfgrass resilience), restorative (lawn absorbs the ability of impacting and not changing its surface characteristics), ball rolls (ball is put into the average distance that rolls behind the surface, lawn), output (tolerance of the clipping of the cutting-out of mowing), green degree (tolerance of the amount of the remaining terrestrial stem in back of mowing), (turfgrass is from by disease biological for degree of taking root (in tangible root growth amount of any one time of the season of growth) and restorability, insect, the ability that the infringement that traffic etc. cause is restored).
The improvement of turfgrass quality can relate to a kind of of the vision mentioned or function qualitative characteristics, or relates to any combination of these qualitative characteristics.
According to the present invention, with under similarity condition but not use " improvement " that identical turfgrass qualitative characteristics that subject methods produces compares be measurable or tangible increase in the qualitative characteristics of given turfgrass.
The improvement of the qualitative characteristics of turfgrass is, for example, and greener or better lawn leaf look.
In a preferred embodiment of the invention, the present composition comprises formula IA compound 3-difluoromethyl-1-methyl isophthalic acid H-pyrazoles-4-carboxylic acid (9-isopropyl-1,2,3,4-tetrahydrochysene-1,4-endo-methylene group-naphthalene-5-yl)-acid amides
Formula IA compound occurs with different stereoisomeric forms in any ratio, and it is described as formula IA
I, IA
II, IA
IIIAnd IA
IVSingle enantiomter:
The mixture of all so single enantiomters and its any ratio is contained in the present invention.
Formula IA compound and they be described in WO 04/035589 from the initial manufacture process of compound known and that can buy.
Formula IA compound can passing type II acid chloride
Amine prepared in reaction with formula III.
The amine of formula III can for example be produced according to flow process 1,2 or 3.
Flow process 1: with the synthetic III of 6-nitro anthranilic acid
The 9-alkylidene of formula D '-the 5-nitro-the benzo norbornadiene can, as people such as L.Paquette, J.Amer.Chem.Soc.99,3734 (1977) describe, Di Ersi-Alder addition by generated in-situ benzyne B ' [for example initial with isoamyl nitrite or nitrite tert-butyl diazotising from the 6-nitro anthranilic acid of formula (A ')] is synthesized, perhaps with reference to or similar R.Muneyuki and H.Tanida, J.Org.Chem.31,1988 (1966), people such as P.Knochel, Angew.Chem.116,4464 (2004), people such as J.W.Coe, Organic Letters 6,1589 (2004), people such as L.Paquette, J.Amer.Chem.Soc.99,3734 (1977), people Molecules such as R.N.Warrener, 6,353 (2001), people Molecules such as R.N.Warrener, 6,194 (2001), from other suitable precursor (referring to people Tetrahedron such as H.Pellissier, 59,701 (2003), R.Muneyuki and H.Tanida, J.Org.Chem.31,1988 (1966)] to 6,6-dimethyl fulvene.
To the suitable aprotic solvent of this step is for example ether, butyl methyl ether, ethyl acetate, carrene, acetone, oxolane, toluene, 2-butanone or dimethoxy-ethane.Range of reaction temperature is a room temperature to 100 ℃, preferred 35-80 ℃.
With reference to people such as M.Neuenschwander, Helv.Chim.Acta, 54,1037 (1971), the source the same 48,955 (1965), people such as R.D.Little, J.Org.Chem.49,1849 (1984), people such as I.Erden, J.Org.Chem.60,813 (1995) and people such as S.Collins, J.Org.Chem.55,3395 (1990), can obtain 6 of formula C ', 6-dimethyl fulvene.
Flow process step hydrogenation in 2: two
With reference to flow process 2, the part hydrogenolysis of passing through D ' for example stops for H after consuming 4 equivalents
2, can obtain the aniline of formula E '.The suitable solvent comprises oxolane, ethyl acetate, methyl alcohol, ethanol, toluene or benzene etc.Catalyzer is for example Ra/Ni, Rh/C or Pd/C.Pressure: the atmospheric pressure or the pressure of 6 crust at the most, preferred atmosphere is pressed.Temperature range is that room temperature arrives 50 ℃ at the most, preferred 20-30 ℃.
The aniline of formula III can obtain from the aniline hydrogenation of formula E '.The suitable solvent is for example oxolane, methyl alcohol, ethanol, toluene, carrene, ethyl acetate.Preferred solvent is oxolane and methyl alcohol.Temperature range is 10 to 50 ℃, preferred 20-30 ℃, and more preferably room temperature.Pressure: atmosphere is pressed onto 150 crust, and preferred atmosphere is pressed onto 100 crust.Suitable/the inverse ratio of selection of catalysts influence.As Rh/C, Rh/Al
2O
3, Rh
2O
3, Pt/C or PtO
2Catalyzer cause syn-enriched (preferred Rh/C).Catalyzer as Ra/Ni, Ir (COD) Py (Pcy) or Pd/C causes trans enrichment (preferred Pd/C).
3: one pots of hydrogenations of flow process
The aniline of formula III can be obtained by one pot reaction by thorough hydrogenation (flow process 3) from formula D ' compound.The suitable solvent is for example oxolane, methyl alcohol, ethanol, toluene or ethyl acetate.Preferred solvent is oxolane or methyl alcohol.Suitable temperature range is a room temperature to 50 ℃, preferably from room temperature to 30 ℃, and room temperature most preferably.Suitable pressure limit is that atmosphere is pressed onto 100 crust, and more preferably atmosphere is pressed onto 50 crust, even more preferably is pressed onto 20 crust from atmosphere, and most preferably atmosphere is pressed onto the 4-6 crust.Similarly, as the description of front flow process 2, the suitable/inverse ratio of selection of catalysts influence.As Rh/C, Rh/Al
2O
3, Rh
2O
3, Pt/C or PtO
2Catalyzer cause syn-enriched.Catalyzer as Pd/C, Ir (COD) Py (Pcy) or Ra/Ni causes trans enrichment (preferred catalyst is Pd/C).
Following embodiment illustrates the production of formula III compound.
A) benzyne addition compound product
Embodiment H1:9-isopropylidene-5-nitro-benzo norbornadiene:
At N
2Under the 72 ℃ of-atmosphere, in 20 minutes with 6-nitro anthranilic acid (110.4g, 0.6mol) and 6,6-dimethyl fulvene (98.5g, 1.5 equivalent) mixture in the 700ml dimethoxy-ethane dropwise adds the nitroso tert-butyl ester (96.3g, 1.4 equivalents) at 2 liter 1, the solution in the 2-dimethoxy-ethane.Get started and form gas tempestuously, temperature rises to 79 ℃.Gas forms and stops behind the 30min.Mixture is cooled to room temperature behind the reflux temperature 3h, evaporates and use on silica gel hexane-eluent ethyl acetate purifying of 95:5, obtains 9-isopropylidene-5-nitro-benzo norbornadiene (76.7g), is yellow solid (m.p.94-95 ℃).
1H-NMR(CDCl3)，ppm：7.70(d，1H)，7.43(d，1H)，7.06(t，1H)，6.99(m，2H)，5.34(brd s，1H)，4.47(brd s，1H)，1.57(2d，6H).
13C-NMR(CDCl
3)，ppm：159.83，154.30，147.33，144.12，142.89，141.93，125.23(2x)，119.32，105.68，50.51，50.44，19.05，18.90。
B) two step hydrogenations
Embodiment H2:9-isopropylidene-5-amino-benzo ENB:
Under 25 ℃ of atmospheric pressure, exist down at Rh/C (1.5g, 5%), hydrogenation 9-isopropylidene in the 50ml oxolane-5-nitro-benzo norbornadiene (5.0g, 22mmol).Behind the hydrogen (2.01 liters or 102% theoretical amount) that consumes 4 equivalents, filter this mixture, evaporation is also used hexane-ethyl acetate-6:1 wash-out purifying on silica gel, provide 9-isopropylidene-5-amino-benzo ENB (2.76g), is (m.p.81-82 ℃ of solid; Output: 62.9% theoretical amount).
1H-NMR (CDCl3), ppm:6.90 (t, 1H), 6.67 (d, 1H), 6.46 (d, 1H), 3.77 (m, 1H), 3.73 (m, 1H), 3.35 (brd, can with D
2The O exchange, 2H), 1.89 (m, 2H), 1.63 (2s, 6H), 1.26 (m, 2H).
13C-NMR (CDCl
3), ppm:148.73,147.65,138.30,131.75,126.19,113.12,110.89,110.19,43.97,39.44,26.98,26.06,19.85,19.75.
Embodiment H3:9-isopropyl-5-amino-benzo ENB:
Under room temperature 100 crust, exist down at Rh/C (100mg, 5%), in the stainless steel autoclave that the 40ml oxolane is arranged, hydrogenation 9-isopropylidene-5-amino-benzo ENB (200mg) obtains 9-isopropyl-5-amino-benzo ENB (suitable/inverse ratio 9:1) with the form of oil.The cis epimer:
1H-NMR (CDCl
3), ppm:6.91 (t, 1H), 6.64 (d, 1H), 6.48 (d, 1H), 3.54 (brd, but D
2The O exchange, 2H), 3.20 (m, 1H), 3.15 (m, 1H), 1.92 (m, 2H), 1.53 (d, 1H), 1.18 (m, 2H), 1.02 (m, 1H), 0.81 (m, 6H);
13C-NMR (CDCl3), ppm:147.73,140.03,130.15,126.41,113.35,112.68,69.00,46.62,42.06,27.74,26.83,25.45,22.32,22.04; Trans epimer:
1H-NMR (CDCl
3), ppm:6.89 (t, 1H), 6.63 (d, 1H), 6.46 (d, 1H), 3.55 (brd, can with D
2The O exchange, 2H), 3.16 (m, 1H), 3.13 (m, 1H), 1.87 (m, 2H), 1.48 (d, 1H), 1.42 (m, 1H), 1.12 (m, 2H), 0.90 (m, 6H);
13C-NMR (CDCl
3), ppm:150.72,138.74,133.63,126.15,112.94,111.53,68.05,45.21,40.61,26.25,24.47,23.55,20.91 (2x).Decision ownership on the NOE-NMR-experiment basis.
C) one pot of hydrogenation:
Embodiment H4:9-isopropyl-5-amino-benzo ENB:
Syn-enriched
There is down the 9-isopropylidene-5-nitro-benzo norbornadiene (35.9g) in the 106h in the thorough hydrogenation 400ml oxolane at Rh/C (25g, 5%).Filter and evaporating solvent with the form of oil obtain 9-isopropyl-5-amino-benzo ENB (32.15g, suitable/inverse ratio 9:1; Output: 97.4% theoretical amount).NMR data: on seeing.
Embodiment H5:9-isopropyl-5-amino-benzo ENB:
Trans enrichment
Depress at atmosphere at room temperature, exist down, the 9-isopropylidene-5-nitro-benzo norbornadiene (41.41g) in 4 hours in thorough 1 liter of oxolane of hydrogenation at Pd/C (22g, 5%).Filter and evaporation subsequently on silica gel with hexane-ethyl acetate-7:1 wash-out purifying with the form of oil provide 9-isopropyl-5-amino-benzo ENB (29.91g, suitable/inverse ratio 3:7; Output: 81.5%).NMR data: on seeing.
In a preferred embodiment of the present invention, the present composition comprises formula IAa compound (cis)
It represents formula IA
ISingle enantiomter, formula IA
IISingle enantiomter or formula IA
IAnd IA
IIThe mixture of arbitrary proportion of single enantiomter.
Preferred these present compositions, it comprises the racemic compound of formula IAa (cis), and the latter represents formula IA
IAnd IA
IIThe racemic mixture of single enantiomter.
In another preferred embodiment of the present invention, the present composition comprises formula IAb (trans) compound
It represents formula IA
IIISingle enantiomter, formula IA
IVSingle enantiomter or formula IA
IIIAnd IA
IVThe mixture of arbitrary proportion of single enantiomter.
In another preferred embodiment of the present invention, the present composition comprises the racemic compound of formula IAb (trans),
The latter represents formula IA
IIIAnd IA
IVThe racemic mixture of single enantiomter.
In another preferred embodiment of the present invention, the present composition comprises formula IAc compound
It represents the epimer mixture of the racemic compound of formula IAa (cis) and IAb (trans), wherein represents formula IA
IAnd IA
IISingle enantiomter racemic mixture formula IAa (cis) racemic compound with represent formula IA
IIIAnd IA
IVThe ratio of formula IAb (trans) racemic compound of racemic mixture of single enantiomter be from 1000:1 to 1:1000.
In another preferred embodiment of the present invention, the present composition comprises formula IAc compound, and it represents the epimer mixture of the racemic compound of formula IAa (cis) and IAb (trans), wherein represents formula IA
IAnd IA
IIThe content of formula IAa (cis) racemic compound of racemic mixture of single enantiomter be 70 to 99% by weight, preferably by weight 85 to 95%.
In another preferred embodiment of the present invention, the present composition comprises formula IAc compound, and it represents the epimer mixture of the racemic compound of formula IAa (cis) and IAb (trans), wherein represents formula IA
IIIAnd IA
IVThe content of formula IAb (trans) racemic compound of racemic mixture of single enantiomter be 60 to 99% by weight, preferably by weight 64 to 70%.
According to the present invention, " racemic mixture " of two enantiomters or " racemic compound " are meant the mixture of two enantiomters of 50:50 ratio basically.
In another preferred embodiment of the present invention, the present composition comprises formula IB compound
According to the present invention, " turfgrass " is understood that annual or perennial grass family (Gramineae).Described grass family preferably belong to Agropyron (Agropyron), Agrostis (Agrostis), carpetweed belong to (Axonopus), Brome (Bromus), buffalo grass (
), Cynodon (Cynodon), ciliate desert-grass belong to (Eremochloa), Festuca (Festuca), Lolium (Lolium), Paspalum (Paspulum), Pennisetum (Pennisetum), ladder forage spp (Phleum), annual bluegrass and belong to (Poa), Herba Stenotaphri helferi and belong to each in belonging to one or more of (Stenotaphrum) or Zoysia (Zoysia).More preferably, described grass family belongs to one or more in Agrostis, buffalo grass, Cynodon, ciliate desert-grass genus, Festuca, Lolium, Paspalum, Pennisetum, annual bluegrass genus, Herba Stenotaphri helferi genus or each genus of Zoysia.
By the present invention, " lawn " is understood that one group of turfgrass, and its mulched ground surface also is subjected to routine servicing.
The present invention can be useful for all turfgrasss, comprises cold-season turfgrass (cool seasonturfgrass) and warm season turf (warm season turfgrass).
The embodiment of cold-season turfgrass is: annual bluegrass belongs to (Poa L.), such as kentucky blue grass (Poa pratensis L.), rough stalked blue grass (Poa trivialis L.), Canada blue grass (Poa compressa L.) and annual bluegrass (Poa annua L.); Creeping bentgrass belongs to (Agrostis L.), such as creeping bentgrass (Agrostis palustris Huds.), thin and delicate creeping bentgrass (Agrostis tenius Sibth.), common creeping bentgrass (Agrostis caninaL.) and redtop (Agrostis alba L.); Festuca (Festuca L.), for example chewing fescue (Festuca rubra L.), bunch type chewing fescue (Festuca rubra var.commutata Gaud.), fescue grass (Festuca ovina L.), hard fescue (Festucalongifolia), alta fascue (Festuca arundinacea Schreb.), meadow fescue (Festuca elatior L.); Lolium (Lolium L.) is such as perennial ryegrass (Loliumperenne L.), Annual Ryegrass (Lolium multiflorum Lam.); Agropyron (Agropyron Gaertn.) is such as wheatgrass (Agropyron cristatum (L.) Gaertn.), sclerophyll couchgrass (Agropyron smithii Rydb.).Other cold-season turfgrass comprises awnless brome (Bromus inermis Leyss.) and ladder forage spp (Phleum L.).
The embodiment of warm season turf is root of bud dog (Cynodon L.C.Rich), Zoysia (Zoysia Willd.), Herba Stenotaphri helferi (Stenotaphrum secundatum (Walt.) Kuntze), centipede grass (Eremochloa ophiuroides (Munro.) Hack.), carpetweed belongs to (Axonopus Beauv.), paspalum notatum (Paspalum notatum Flugge.), West Africa pearl millet (Pennisetum clandestinum Hochst.ex Chiov.), buffalograss (Buchloe dactyloides (Nutt.) Engelm.) and seashore paspalum (Paspalumvaginatum swartz).
The inventive method is effective to protecting the antagonism of turfgrass or its seed to cause plant characteristic of disease fungi.
It is effective that the inventive method is resisted following disease to the protection turfgrass: Ascochyta (Ascochyta) leaf blight; brown yellow rust; Cephalosporium (Cephalosporium) yellow rust; Cercospora (Cercospora) leaf spot; Cladosporium (Cladosporium) eye spot; copper spot (Copper Spot (banded leaf spot)); dollar spot; gray leaf spot; leaf blister (moire disease); leaf smut; little bare hull belongs to (Leptoshaerulina) leaf blight; flagellum spore leaf spot; Phyllosticta (Phyllosticta) leaf blight; joint Chytridium (Physoderma) leaf spot; joint chytrid leaf stripe; pink colour patch leaf blight; breast frost (Cream) leaf blight; powdery mildew; false Septoria (Pseudoseptoria) leaf spot; red spiral disease (Red Thread); rust; Septoria (Septoria) leaf spot; the many spores of shell belong to (Stagnospora) leaf spot; snow mold; Coprinus (Coprinus) snow mold; microtorr belongs to (Microdochium) patch disease; snow mold (Snow Scald); nuclear coral Pseudomonas (Typhula) fusarium wilt; androspore belongs to (Spermospora) leaf spot; pitch spot disease (Tar Sport); yellow lawn disease (downy mildew); anthracnose; bipolar Pseudomonas (Bipolaris) disease; the mould genus of bright navel (Exseohilum) disease; Curvularia (Curvularia) disease; in domestic navel Helminthosporium (Drechslera) disease; the Marielliottia disease; Fusarium (Fusarium) disease; Nigrospora (Nigrospora) fusarium wilt; pythium (Pythium) disease; Rhizoctonia (Rhizoctonia) disease; the rice shoot disease; the south fusarium wilt; dead pinta; necrotic ring spot; the root decline of warm season turf; spring dead pinta; summer the patch disease; brown plaque disease or full rot.Described disease is described in " Compendium of Turfgrass Diseases " (by R.W.Smiley, P.H.Dernoeden and B.B.Clarke, the third edition, AmericanPhytopathological Society Press) with relevant pathogen.
The inventive method is effective especially to the anti-following disease of protection turfgrass: standing grain is given birth to thorn dish spore (Colletotrichum graminicola); pythium (Pythium spp.); Rhizoctonia solani Kuhn (Rhizoctonia solani); with fruit stone cup fungi (Sclerotiniahomeocarpa); gaeumannomyce (Gaeumannomyces graminis); avenge rotten microtorr bacterium (Microdochium nivale); meat spore nuclear coral bacterium (Typhula incarnata); domestic navel Helminthosporium (Drechsleraspp.) in the anti-rice blast fungus of marine microorganism (Pyricularia grisea); Marielliottia spp.; bipolar Pseudomonas (Bipolaris spp.); Curvularia (Curvularia spp.) or the mould genus of bright navel (Exserohilum spp.).
It is effective especially that the inventive method is given birth to thorn dish spore to protection turfgrass antagonism with fruit stone cup fungi, Rhizoctonia solani Kuhn, standing grain.
The inventive method is effective especially with the fruit stone cup fungi to the antagonism of protection turfgrass.
The inventive method is effective especially to protection turfgrass antagonism Rhizoctonia solani Kuhn.
The inventive method is effective especially to the living thorn dish of protection turfgrass antagonism standing grain spore.
The seed that turfgrass maybe will be placed in the place that " location " of term turfgrass used herein is intended to contain place, the sowing of turfgrass seed of turfgrass growth is with the place of growing plant subsequently.According to the present invention, " location " on lawn can relate to soil or matrix.This on-site embodiment is a golf course of managing turfgrass thereon.
According to the present invention, term " soil " expression generally appears at the natural soil of land area, and such as the soil that appears at golf course, perhaps expression is through the soil of modification, such as granulating and/or the soil handled with agricultural chemicals such as fertilizer.The embodiment of granulating and/or the soil handled is disclosed in US-5,265,372.
According to the present invention, term " matrix " expression is used for the media of growth such as turfgrass, and it is fit to be applied to multiple already present land structures.General, this media is the no earth mixtures of the elastic granule that comprises enough ratios, suitable adhesive emulsion, mineral aggregation, filler and sustained release plant nutrition particulate component, so produce porous, the matrix with transparent air bag of root system of turfgrass springy sprawling and solidify the described mixture in back.The turfgrass of growing on described matrix can form the lawn, and this lawn can be applied to pore-free surface for example roof, terrace and other crust zone of building, perhaps is applied to porous surface for example football field and golf course.The embodiment of this matrix is described in WO 2005/002323.Elastic granule can be, for example, rubber grain, reclaims doughnut rubber grain or its mixture.
By handle turfgrass, its location or its seed with the present composition present composition is applied to turfgrass or its seed.
The amount of application of the present composition depends on various factors, such as main body such as plant, location or the seed handled; Type such as spraying, spread or the seed dressing handled; The purpose of handling is as prevention purpose or therapeutic purposes; The fungi type of control; Time of application; Environmental condition or lawn grass variety.
In an embodiment of the invention, by the present composition being applied to this turfgrass with present composition processing turfgrass or its location.
In yet another embodiment of the present invention, by handling turfgrass the present composition is applied to this turfgrass with the present composition.
In yet another embodiment of the present invention, by the location of handling turfgrass with the present composition present composition is applied to this turfgrass.
In yet another embodiment of the present invention, by the seed of handling turfgrass with the present composition present composition is applied to this seed.
To using of turfgrass:
The present composition can be applied to this turfgrass by handling turfgrass with the present composition.In described embodiment of the present invention, preferably the present composition is applied to this turfgrass by spraying and spread.Turfgrass is handled and can be implemented by meadow maintenance operator.
Be high-quality, the healthy turfgrass of maintenance on the target area in soil such as golf course, sports ground, park district or family meadow; perhaps for the described turfgrass antagonism of protection causes phytopathy venereal disease evil, one or many is used the present composition to this turfgrass between this turfgrass defects liability period.
Preferably, one or many is used the present composition to this turfgrass during the growth season of this turfgrass.
Use the present composition, can suppress or eliminates the pathogen that appears on the turfgrass and the part of protecting turfgrass to grow afterwards simultaneously and avoid pathogen and attack.
The present composition can be before this turfgrass be by this fungal infection (" Prevention Processing ") or afterwards (" treatment is handled ") use.
When turfgrass is used, formula I compound generally with 10 to 2000g/ha, preferred 100 to 1000g/ha, more preferably 200 to 800g/ha, most preferably 250 to 600g/ha ratio is used.
Use to the on-site of turfgrass:
' using ' to the location contain liquid (sprayable) or particle (ai on the inert substance or ai on fertilizer) use
The present composition can be applied to this turfgrass by the location of handling turfgrass with the present composition.
For example, can before or after the seed of turfgrass is sowed or be placed in the soil, the present composition be applied to this soil;
Before or after perhaps can being placed in the matrix at the seed of turfgrass the present composition be applied to this matrix;
Perhaps can the present composition be applied to this soil before being placed on the soil top together being grown in turfgrass on the matrix and this matrix.
In one embodiment, said composition is applied to turfgrass as sprayable liquid preparation.In another embodiment, said composition is applied to turfgrass as granular preparation.Suitable particle comprises inertia and fertiliser granulates.This active component is scattered in whole particle, is impregnated in the particle or is coated on particle surface.
To using of turfgrass seed:
By handling the seed that seed is applied to The compounds of this invention this turfgrass with The compounds of this invention.
When handling kind of a period of the day from 11 p.m. to 1 a.m with The compounds of this invention, 0.001 to 50g the every kg seed of formula I compound, preferred 0.01 normally enough to the ratio of the every kg seed of 10g.
Composition of the present invention can any habitual form use, for example with following form: pack in pairs (twin pack), the dry powder doses (DS) that is used for seed treatment, the emulsion (ES) that is used for seed treatment, the suspension concentrates (FS) that is used for seed treatment, the liquor (LS) that is used for seed treatment, the water-dispersible powder (WS) that is used for seed treatment, the microcapsule suspending agent (CF) that is used for seed treatment, the jelly (GF) that is used for seed treatment, missible oil (EC), suspension concentrates (SC), suspension emulsion (SE), micro-capsule suspension (CS), water-dispersible granules (WG), breast granula (EG), oil emu (EO), aqueous emulsion (EW), microemulsion (ME), oil dispersant (OD), dense finish (OF) can flow, finish (OL), solvable dense dose (SL), ultra low volume suspension (SU), ultra low volume liquids (UL), mother liquor (TK), can disperse dense dose (DC), the technical feasible preparation that wetting powder (WP) or auxiliary agent any and can be agricultural are united.
The described present composition can ways customary production, for example by formula I compound is mixed with at least a appropriate formulation auxiliary agent.
Term of the present invention " formulation auxiliary agents " expression is made up with formula I compound so that its natural or synthetic organic or inorganic material of using to the lawn.So this auxiliary agent generally is an inertia, it must be that particularly the lawn is acceptable on the agricultural.
The said preparation auxiliary agent can be carrier or surfactant.Can exist in the present composition more than a kind of auxiliary agent, can exist in such embodiment more than a kind of carrier and/or more than a kind of surfactant, a non-restrictive example can be a kind of carrier and two kinds of surfactants.
Should " carrier " can be liquid carrier (water, alcohol, ketone, petroleum distillate, aromatic hydrocarbon or alkane, chlorinated hydrocabon, liquid gas etc.) or solid-state carrier.
Suitable liquid carrier is, but is not limited to: particularly as the C of xylene mixture or replacement naphthalene
8To C
12The aromatic hydrocarbons of part, phthalate as dibutyl phthalate or dioctyl phthalate, dibenzoic acid dipropylene glycol ester, aliphatic hydrocarbon as cyclohexane or paraffin, as alcohols and glycols and ether, ester and the diester of glycol monoethyl ether, as the ketone of cyclohexanone, such as but not limited to the intensive polar solvent of N-N-methyl-2-2-pyrrolidone N-, methyl-sulfoxide or dimethyl formamide, and when suitable, epoxidized vegetable oil or soybean oil; Or water.
Suitable solid-state carrier is, but is not limited to: alumina silicate, urea, sodium sulphate, talcum, calcium sulphate or potassium sulphate.
According to the present invention, single mixture of planting carrier or two or more carriers may reside in the present composition.
" surfactant " is nonionic, cation, both sexes and/or the anion surfactant with well emulsify, dispersion and moistening character.According to the present invention, can there be single surfactant or one or more surfactant mixtures of planting.Surfactant habitual in the preparation technique is described in the particularly following publication: " McCutcheon ' s Detergents andEmulsifiers Annual ", MC Publishing Corp., Glen Rock, N.J., 1988 and M. and J.Ash, " Encyclopedia of Surfactants ", Vol.I-III, Chemical Publishing Co., New York, 1980-1981.
That can mention in the surfactant has; for example, polyacrylate; the lignin sulfonic acid salt; phenolsulfonic acid or (single-or two-alkyl) naphthalenesulfonate; lauryl sulfate; the condensation polymer of oxirane and lignosulfonates; oxirane and fatty alcohol or and fatty acid or and the condensation polymer of fatty amine; substituted phenol (particularly as single-or two-(polyalkylene oxide alkyl phenol) phosphoric acid salts; the induced by alkyl hydroxybenzene of polyalkylene oxide alkyl phenol metal carboxylate or polyalkylene oxide alkylphenol sulfate class or aryl phenols); sulfosuccinate; taurine derivatives (particularly alkyl taurine class); the condensation polymer of the phosphate of the condensation polymer of oxirane and phosphorylation triphenyl vinyl phenol and oxirane and alcohol or phenol.
Thinner in the seed dressing formulation of using the present composition and suiting, the preparation of will dressing seed is applied to seed in a manner known way, and this suitable seed dressing formulation is as having outstanding agent of the adhesive water-based of good seed or dry powder doses form.Described seed dressing formulation is known in the art.Seed dressing for example can comprise the active component as the encapsulated form of spansule or microcapsules in the preparation.
The present composition can comprise one or more formulation additives, such as but be not limited to biocide, antifreeze, sticker, thickener and the compound of auxiliaring effect is provided.
The present composition can comprise one or more extra active components, such as, fungicide, Insecticides (tech) ﹠ Herbicides (tech) or growth regulator.Embodiment can be the composition that comprises another kind of fungicide.Any suitable fungicide or weed killer herbicide can be used for composition, and adduction by this active component or synergy come, control to wide spectrum damage by disease and insect more for example is provided, overcome problem and postpone resistance generation, the effectiveness of improvement is provided.
In one embodiment, the present composition comprises and is selected from one or more extra active components that following inventory comprises: Fluoxastrobin, propiconazole, tpn, Difenoconazole, fludioxonil, Metalaxyl-M, cyprodinil, thiophanate-methyl, iprodione, triazolone, Propamocarb, phosethyl-Al, flutalonil, pyraclostrobin, Boscalid (boscalid), vinclozolin, oxime bacterium ester, nitrile bacterium azoles, Fenarimol, phosphite ester and fluoxastrobin.Preferably, the present composition comprises Fluoxastrobin, propiconazole or tpn.
In an embodiment of the invention, the present composition does not comprise extra active component.The method that this embodiment is provided on the turfgrass or control causes phytopathy venereal disease evil on its seed, it comprises to this turfgrass, its location or its seed uses composition, and described composition removes formulation auxiliary agents and comprises basically the active component of being made up of the dynamic isomer of the formula I compound of antifungal effective dose or this compound.
In another embodiment, be provided on the turfgrass or control causes phytopathy venereal disease evil on its seed method, it comprises to this turfgrass, its location or its seed uses composition, and described composition removes formulation auxiliary agents and comprises the active component of being made up of the dynamic isomer of the formula I compound of antifungal effective dose or this compound.
Usually, the present composition comprises 0.01 to 90% by weight formula I compound, 0 to 20% surfactant and 10 to 99.99% carrier.
The conc forms of the present composition generally includes about 2-80%, preferred about 5-70% formula I compound by weight.The administration form of preparation can for example comprise 0.01 to 20% by weight, preferred 0.01 to 5% by weight formula I compound.In view of commercial product is a concentrate by preparation preferably, the terminal use will adopt the preparation of dilution usually.
The following example illustrates the present invention, " active component " expression I compound.
Example of formulations
Wetting powderA) c b))
Active component 25% 50% 75%
Sodium lignin sulfonate 5% 5%-
NaLS 3%-5%
Diisobutyl sodium naphthalene sulfonate-6% 10%
Phenol polyglycol ether-2%-
(7-8mol oxirane)
The silicic acid of high dispersive 5% 10% 10%
Kaolin 62% 27%-
Active component is mixed fully with auxiliary agent, and described mixture fully grinds in suitable grinding machine, obtain wetting powder, but its thin up provides the suspending agent that requires concentration.
The seed treatment dry powder dosesA) c b))
Active component 25% 50% 75%
Light mineral matter oil 5% 5% 5%
The silicic acid of high dispersive 5% 5%-
Kaolin 65% 40%-
Talcum-20
Active component is mixed fully with auxiliary agent, and described mixture fully grinds in suitable grinding machine, obtains being directly used in the pulvis of seed treatment.
Missible oil
Active component 10%
Octylphenol polyethylene glycol ether 3%
(4-5mol oxirane)
Calcium dodecyl benzene sulfonate 3%
Castor oil polyglycol ether (35mol oxirane) 4%
Cyclohexanone 30%
Xylene mixture 50%
Can pass through the above-mentioned concentrate of dilute with water, obtain can be used for any required dilution emulsion of plant protection.
PulvisA) c b))
Active component 5% 6% 4%
Talcum 95%--
Kaolin-94%-
Mineral filler--96%
Grind this mixture by mixed active composition and carrier and in suitable grinding machine and obtain the i.e. pulvis of usefulness.Described pulvis can also be used for doing of seed and apply.
Extrude granule
Active component 15%
Sodium lignin sulfonate 2%
Carboxymethyl cellulose 1%
Kaolin 82%
Used additives mixes with active component and grinds, with this mixture of water-wet.It is dry in air flow that mixture is extruded the back.
The coated particle agent
Active component 8%
Polyethylene glycol (mol.wt.200) 3%
Kaolin 89%
In agitator, the active component that fully grinds is applied to equably with the moistening kaolin of polyethylene glycol.Can not obtain the coated particle agent of dirt in this way.
Suspension concentrates
Active component 40%
Propane diols 10%
Nonoxynol-9 (15mol oxirane) 6%
Sodium lignin sulfonate 10%
Carboxymethyl cellulose 1%
Silicone oil (75% aqueous emulsion form) 1%
Water 32%
Used additives mixes with the active component of fine gtinding, obtains suspension concentrates, and the dilute with water latter can obtain to require arbitrarily dilution suspending agent.By spraying, perfusion or immersion, can handle plant alive and plant propagation material and protect its combating microorganisms to infect with this thinner.
The seed treatment suspension concentrates
Active component 40%
Propane diols 5%
Butanols PO/EO copolymer 2%
Triphenylethylene phenol and 10-20 mole EO 2%
1,2-benzisothiazole-3-ketone (20% aqueous solution form) 0.5%
Monoazo pigment calcium salt 5%
Silicone oil (75% aqueous emulsion form) 0.2%
Water 45.3%
Used additives mixes with the active component of fine gtinding, obtains suspension concentrates, and the dilute with water latter can obtain to require arbitrarily dilution suspending agent.By spraying, perfusion or immersion, can handle plant alive and plant propagation material and protect its combating microorganisms to infect with this thinner.
The spansule suspending agent
28 parts of formula I compounds mix with 2 parts of aromatic solvents and 7 parts of toluene di-isocyanate(TDI)/polymethylene-many phenyl isocyanate-mixtures (8:1).The emulsification in the mixture of 1.2 parts of polyvinyl alcohol, 0.05 part of defoamer and 51.6 parts of water of this mixture is up to meeting the requirements of particle scale.Add in 5.3 parts of water 2.8 part 1, the mixture of 6-diamino hexane to this emulsion.Stir the mixture and finish until polymerisation.
By adding 0.25 part of thickener and 3 parts of dispersants with the stable micro-capsule suspension that obtains.This micro-capsule suspension preparation comprises 28% active component.This capsule diameter intermediate value is the 8-15 micron.
In suitable device, the preparation that obtains is applied to seed as aqueous suspension agent.
Biological Examples
Embodiment B-1: use the grass that infects with fruit stone cup fungi (Sclerotinia homoeocarpa)
The processing of level ground grass (creeping bentgrass (Creeping Bentgrass))
Prepare following EC preparation:
| Component (with %w/v) | A | B |
| Formula IAc compound (suitable/inverse ratio=9:1) | 10.0 | 0 |
| Pyrrole metsulfovax (Penthiopyrad) * | 0 | 10.0 |
| Ethyl lactate | 20.0 | 20.0 |
| Castor oil/PEO-copolymer | 6.0 | 6.0 |
| Calcium dodecyl benzene sulfonate | 4.0 | 4.0 |
| Triphenylethylene phenol/PEO-copolymer | 2.0 | 2.0 |
| Acetophenone | 58.0 | 58.0 |
*Known from JP-2004-123587
To be seeded in the nursery (Plots) with creeping bentgrass (the Agrostis palustris Huds.) seed that the fruit stone cup fungi is infected, spray on the nursery with a certain amount of preparation A and B then corresponding to the dosage that provides in the following table and represent with g/ha.Repeat this processing three times with the interval of handling 1 time every 14 days.Behind last 19 days of handling, the incidence of visual evaluation disease and seriousness.In untreated creeping bentgrass, this creeping bentgrass of 60% has shown the disease symptom.The disease control rate provides with the disease control rate % with untreated creeping bentgrass comparison.
The table B-1: on creeping bentgrass to control with the fruit stone cup fungi
| Product | Ratio g ai/ha | Disease control rate % |
| Preparation A-Compound I Ac | 250 | 68％ |
| Preparation A-Compound I Ac | 350 | 82％ |
| Preparation A-Compound I Ac | 500 | 93％ |
| Preparation B-pyrrole metsulfovax | 250 | 48％ |
| Preparation B-pyrrole metsulfovax | 350 | 52％ |
| Preparation B-pyrrole metsulfovax | 500 | 57％ |
The result of table B-1 shows that at the rate of application of 250-500g ai/ha, Compound I Ac prevents and treats with the fruit stone cup fungi on creeping bentgrass than pyrrole metsulfovax is more capable.For example, the 500g/ha ratio use the pyrrole metsulfovax can level 57% on same fruit stone cup fungi on the control creeping bentgrass.Contrast with it, Compound I Ac can prevent and treat this disease on 93% level.
Embodiment B-2: use the processing of the turfgrass (kentucky blue grass) that infects with the fruit stone cup fungi
To be seeded in the nursery with kentucky blue grass (the Poa pratensis L.) seed that the fruit stone cup fungi is infected, spray on the nursery with a certain amount of preparation A and B then corresponding to the dosage that provides in the following table and represent with g/ha.Repeat this processing three times with the interval of handling 1 time every 14 days.Behind last 19 days of handling, the incidence of visual evaluation disease and seriousness.In untreated kentucky blue grass, this kentucky blue grass of 58% has shown the disease symptom.The disease control rate provides with the disease control rate % with untreated kentucky blue grass comparison.
The table B-2: on kentucky blue grass to control with the fruit stone cup fungi
| Product | Ratio g ai/ha | Disease control rate % |
| Preparation A-Compound I Ac | 250 | 62％ |
| Preparation A-Compound I Ac | 350 | 62％ |
| Preparation A-Compound I Ac | 500 | 88％ |
| Preparation B-pyrrole metsulfovax | 250 | 52％ |
| Preparation B-pyrrole metsulfovax | 350 | 24％ |
| Preparation B-pyrrole metsulfovax | 500 | 21％ |
The result of table B-2 shows that at the rate of application of 250-500g ai/ha, Compound I Ac prevents and treats with the fruit stone cup fungi on creeping bentgrass than pyrrole metsulfovax is more capable.For example, the 500g/ha ratio use the pyrrole metsulfovax can level 21% on the same fruit stone cup fungi of control creeping bentgrass.Contrast with it, Compound I Ac can prevent and treat this disease on 88% level.
Embodiment B-3: give birth to thorn dish spore (Colletotrichum graminicola) with standing grain and invade
The processing of the turfgrass that dyes (annual bluegrass/creeping bentgrass)
Prepare following EC preparation:
| Component (%w/w) | C |
| Formula IAc compound (suitable/inverse ratio=9:1) | 12.5 |
| Castor oil/PEO-copolymer | 3.3 |
| Calcium dodecyl benzene sulfonate | 5.0 |
| Triphenylethylene phenol/PEO-copolymer | 1.7 |
| Dibenzoic acid dipropylene glycol ester Ergol acetophenone | 24 24 29.5 |
Nursery with the mixing grass of a certain amount of formulation C handled natural infection annual bluegrass (Poa annua) of standing grain life thorn dish spore (Colletotrichum graminicola) and creeping bentgrass (Agrostis stolifera) corresponding to the dosage that provides in the following table and represent with g ai/ha.Dosage corresponding to 250g ai/ha is sprayed four times with 14 days interval.Dosage corresponding to 500g ai/ha is sprayed three times with 21 days interval.After use for the last time at 250g ai/ha dosage 23 days, and 500g ai/ha dosage is after use for the last time 10 days, visual evaluation disease seriousness.In the mixing grass of untreated annual bluegrass/creeping bentgrass, 44% this zone, lawn has shown the disease symptom.The disease control rate is to provide with untreated nursery disease control rate % relatively.
Table B-3: the control of on annual bluegrass genus/creeping bentgrass belongs to, standing grain being given birth to thorn dish spore
The result of table B-3 shows that at the rate of application of 500g ai/ha, Compound I Ac is than Daconil Weather
The more capable standing grain of preventing and treating on annual bluegrass/creeping bentgrass mixing grass is given birth to thorn dish spore.For example, 7330g ai/ha's and DaconilWeather to use at interval in 14 days
Can on 81% level, prevent and treat standing grain and give birth to thorn dish spore.Contrast with it, 500gai/ha's and can on 92% level, prevent and treat this disease with the Compound I Ac that used at interval in 21 days.
Embodiment B-4: the turfgrass (thin and delicate creeping bentgrass (Colonial that infects with Rhizoctonia solani Kuhn
Bentgrass)) processing
With a certain amount of formulation C processing natural infection corresponding to the dosage that provides in the following table and represent with g ai/ha the nursery of thin and delicate creeping bentgrass (Agrostis tenius Sibth.) of Rhizoctonia solani Kuhn (Rhizoctonia solani).Dosage corresponding to 302g ai/ha is sprayed three times with 14 days interval.Corresponding to the dosage of 604g ai/ha interval spraying secondary with 28 days.Behind two kinds of last 21 days of handling of ratio, the incidence of visual evaluation disease and seriousness.In untreated thin and delicate creeping bentgrass, 80% this zone, lawn has shown the disease symptom.The disease control rate is to provide with untreated nursery disease control rate % relatively.
Table B-4: on thin and delicate creeping bentgrass to the control of Rhizoctonia solani Kuhn
The result of table B-4 shows that at the rate of application of 304g ai/ha, compound 1Ac is than Daconil Weather
More capablely on thin and delicate creeping bentgrass, prevent and treat Rhizoctonia solani Kuhn.For example, 8238g ai/ha and Daconil Weather to use at interval in 14 days
Can on 71% level, prevent and treat Rhizoctonia solani Kuhn.Contrast with it, 302g ai/ha also can prevent and treat this disease with the compound 1Ac that used at interval in 14 days on 97% level.
Another aspect of the present invention is that the plant of natural life circulation and/or the natural materials of animal origin are taken from protection; and/or the method for its treated form antagonism fungal infection; it comprises to the natural materials of described plant and/or animal origin or its treated form uses composition, and described composition comprises at least a formula I compound of antifungal effective dose except that formulation auxiliary agents
Wherein A is
Or
Or the dynamic isomer of this compound.
According to the present invention, expression that term " is taken from the natural materials of the plant origin of natural life circulation " is from plant or its part of natural life circulation results, and it is in the form of fresh results.The embodiment of the natural materials of this plant origin is: stem, leaf, stem tuber, seed, fruit or seed.According to the present invention, term " the treated form of the natural materials of plant origin " is interpreted as the form of the natural materials of the plant origin that expression is obtained by modifying process.This modifying process can be used to the natural materials of plant origin is changed into the form that is more suitable for preserving (reserve substance) of this material.The embodiment of this modifying process is: predry, wetting, crushing, pulverize, grind (grounding), squeezing or baking.Timber also belongs to the treated form of the natural materials of defined plant origin, no matter is the natural timber form as construction timber, electric pole and fence, or as the furniture made with timber or the finished product form of object.
According to the present invention, term " is taken from natural materials and/or its treated form of the animal origin of natural life circulation " and is interpreted as the material of representing animal origin, such as skin, rawhide, leather, animal skin, hair etc.
Combination of the present invention can prevent disadvantageous consequence, such as addle, variable color or mouldy.
Preferred embodiment be natural materials and/or its treated form that the plant origin of natural life circulation is taken from protection; the method of antagonism fungal infection; it comprises to the natural materials of described plant and/or animal origin or its treated form uses composition, and described composition removes at least a formula I compound that formulation auxiliary agents comprises the antifungal effective dose.
Another preferred embodiment is to protect the fruit of preferred a kind of fruit, such as apple, pear, etc., drupe, berry and the citrus fruit of taking from natural life circulation and/or the method for its treated form; it comprises to described fruit and/or its treated form uses composition, and described composition removes at least a formula I compound that formulation auxiliary agents comprises the antifungal effective dose.
In a preferred implementation of this respect of the present invention, the present composition comprises formula IA compound
In another preferred implementation of this respect of the present invention, the present composition comprises formula IB compound
In another preferred implementation of this respect of the present invention, the present composition comprises the active component of being made up of the formula I compound of antifungal effective dose basically.
In another preferred implementation of this respect of the present invention, the present composition comprises the active component of being made up of the formula I compound of antifungal effective dose.
The present composition also can be used for protecting the field of construction material antagonism fungal infection.
In another aspect of the present invention, prevention is provided and/or has handled conk on construction material and/or the method that infects, comprised with comprising the composition of active components of forming by the formula I compound of antifungal effective dose basically and handle described material
Wherein A is
Or the dynamic isomer of this compound.
In specific implementations of the present invention, the present composition comprises the active component of being made up of formula IA compound basically
In yet another embodiment of the present invention, the present composition comprises the active component of being made up of formula IB compound basically
In another aspect of the present invention, provide purposes in the method for the conk of above-mentioned composition on the control construction material.
" construction material " represents the material that those are used to build etc.Especially, construction material comprises wallboard, structural timber, door, cupboard, storage unit, carpet, particularly as native fiber carpet, soft furniture, wall or the smallpox paperboard of wool and burlap, and other surface wall, floor or ceiling as coating with lacquer, coating, plastics, wood (comprising engineered wood) and wood-plastic composite (WPC).As a supplement, construction material comprises adhesive, sealant, attachment material and joint and insulating materials.In a specific implementations, construction material is represented wallboard.In another embodiment, construction material is represented structural timber.In another embodiment, construction material is represented engineered wood.Represent plastics at another construction material.Plastics comprise plastic polymer and copolymer, comprising: the combination of acrylonitrile-butadiene base-styrol copolymer, butyl rubber, epoxy resin, fluoropolymer polymer, isoprene rubber, nylon, polyethylene, polyurethane, polypropylene, polyvinyl chloride, polystyrene, Merlon, polyvinylidene fluoride, polyacrylate, polymethyl methacrylate, polyurethane, polybutene, polybutyl terapthalate, polyether sulfone, polyphenylene oxide, polyphenylene oxide, polyphenylene sulfide, polyphthalamide, polysulfones, polyester, silicones, butadiene-styrene rubber and polymer.In another embodiment, construction material is represented polyvinyl chloride (PVC).In another embodiment, construction material is represented polyurethane (PU).In another embodiment, construction material is represented coating.In another embodiment, construction material is represented wood-plastic composite (WPC) (WPC).Wood-plastic composite (WPC) is a material well known in the art.Can in following publication, find summary-Craig Clemons-Forrest Products Journal June2002 Vol 52.No.6.pp 10-18 of WPCs.
" timber " is interpreted as expression timber and wood products, for example: the Wood products of deriving, sheet material, laminate, plywood, flakeboard, laminated beam, oriented yarn plate (oriented strandboard), hardboard and coreboard; The papery food product packets, tropical wood, structural timber, wooden frame, roadbed wood, bridge, harbour part, the wooden vehicles, box, supporting plate, container, telegram-bar, wooden hedge, the wooden heat-insulating layer, the door and window that timber, laminate, plywood are made, joinery, perhaps in construction joiner through being usually used in the timber product on house or deck, or in comprising the building construction of engineered wood, engineering and carpenter normally used wooden article.
By the description in this specification, the inventive method can be used for prevention and/or handle fungi growth/infect.By handling fungi or construction material with fungicide of the present invention, can prevent and treat this fungi in mode easily.The example that available fungicide of the present invention is handled the method for fungi or construction material is: by described fungicide being included in the construction material self, absorbing, dipping, handle (in the pressure or vacuum systems of sealing) described material, dip-coating or immersion construction material with described fungicide, or for example by the coating of curtain membrane type, roller, brush, spraying, atomize, dust, disperse or pour to use and coat construction material.
In another aspect of the present invention, provide the method for producing treated construction material, it comprises fungicide of the present invention from the antifungal effective dose to described material that use, so that prevent and/or delay the fungal infection of described material.
In another aspect of the present invention, provide the method for handling treated construction material once more, it comprises fungicide of the present invention from the antifungal effective dose to described material that use, so that prevent and/or delay the fungal infection of described material.
The present invention also further provides by the available construction material of aforesaid method.
In another aspect of the present invention, provide the construction material of handling with the fungicide of the present invention of the antifungal effective dose of having prevented the conk on the described material.
The present invention also further provides the building that comprises above-mentioned construction material.In a specific implementations, described building is a temporary building.In another embodiment, described building is a permanent structure.
In another aspect of the present invention, provide fungicide of the present invention on described material, handling construction material as mentioned above with the purposes in the method for prevention and/or processing fungal infection.
The fungi example that throws into question is: chain lattice spore (Alternaria alternata), utmost point alternaria tenuis (Alternaria tenuissima), Aureobasidium pullulans (Aureobasidiumpullulans), aspergillus flavus (Aspergillus flavus), aspergillus niger (Aspergillusniger), Aspergillus terreus (Aspergillus terreus), aspergillus fumigatus (Aspergillusfumigatus), aspergillus repens (Aspergillus repens), aspergillus versicolor (Aspergillusversicolor), candida albicans (Candida albicans), dendritic spore of tooth (Cladosporium cladosporioides), draft branch spore (Cladosporiumherbarum), ball spore branch spore (Cladosporium sphaerospermum), cellar fungus (Coniophora puteana), knee curvature spore (Curvularia genticulata), Diplodia natalensis (Diplodia natalensis), cotton-shaped epidermis moss bacterium (Epidermophytonfloccosum), fusarium oxysporum (Fusarium oxysporum), green sticking broom mould (Gliocladiumvirens), gloeophyllum trabeum (Gloeophyllum trabeum) grey humicola lanuginosa (Humicolagrisea), sudden change flask shape mould (Lecythophora mutabilis), tazza shape mushroom (Lentinus cyathiformis), lentinus lepideus (Lentinus lepidus), Ci Heiwu mould (Memnionella echinata), indication Mucor (Mucor indicus), Mucor racemosus (Mucor racemosus), Oligoporus placenta, Paecilomyces varioti (Paecilomycesvariotii), Penicillium citrinum (Penicillium citrinum), penicillium funiculosum (Penicilliumfuniculosum), green ochre mould (Penicillium ochrochloron), penicillium purpurogenum (Penicillium purpurogenum), have a liking for loose mould (Penicillium pinophilum), penicillium variable (Penicillium variabile), bristle Peter shell (Petriellasetifera), Phanerochaete chrysosporium (Phanerochaete chrysosporium), stem point belongs to chromabacterium biolaceum (Phoma violacea), continuous rotten transverse hole fungus (Poria placenta), rhodothece rubra (Rhodotorula rubra), schizophyllum commune (Schizophyllum commune), Sclerophoma phytiophila short handle broom mould (Scopulariopsis brevicaulis), dry rot fungus (Serpula lacrymans), shadow yeast (Sporobolomyces roseus), Stachybotrys atra (Stachybotrys atra), paper shape Stachybotrys atra (Stachybotryschartarum), Stemphylium dendriticum, palpus hair moss bacterium (Trichophytonmentagrophytes), spiral pieces mould (Trichurus spiralis), red hair moss bacterium (Trichophyton rubrum), black thin basic lattice spore (Ulocladium atrum) and paper list are every spore (Ulocladium chartarum).
What need pay special attention to is: the dendritic branch of chain lattice spore, Alternaria tenuissima, aspergillus niger, aspergillus versicolor, Aureobasidium pullulans, bud spore, cellar fungus, gloeophyllum trabeum, Ci Heiwu are mould, indication Mucor, Oligoporus placenta, Penicillium citrinum, penicillium funiculosum, have a liking for loose mould, Sclerophomaphytiophila, Stachybotrys atra, paper shape Stachybotrys atra and paper list every spore.
The present composition is effective especially to following results back disease, such as Botrytis cinerea (Botrytis cinerea), Colletotrichum musae, curved spore (Curvularialunata), half-naked sickle spore (Fusarium semitecum), bacterium (Geotrichumcandidum) in vain, peach brown rot fungus (Monilinia fructicola), a kind of fruit, such as apple, pear, etc. clump stalk spore (Monilinia fructigena), drupe brown rot fungus (Monilinia laxa), pyriform Mucor (Mucor piriformis), Italy's mould (Penicilium italicum), from giving birth to mould (Penicilium solitum), Penicillium digitatum (Penicillium digitatum) or penicillium expansum (Penicillium expansum), particularly resist the pathogen of following fruit: such as a kind of fruit, such as apple, pear, etc. such as apple and pears, drupe such as peach, Lee, citrus fruit, muskmelon, pawpaw, kiwi fruit, mango, berry such as strawberry, avocado, pomegranate and banana, and nut.
The amount of application of the present invention's combination will depend on multiple factor, such as the compound that adopts; The main body of handling, such as, for example take from the plant of natural life circulation and/or natural materials and/or its treated form of animal origin; Construction material; The form of handling, such as, for example spray, dust or spread or the fungi type that will prevent and treat.
By handling fungi with the present composition, being subjected to the plant of the natural life circulation of taking from of fungal attack threat and/or natural materials and/or its treated form or the construction material of animal origin, use the present composition.
Can before or after the natural materials and/or its treated form or construction material of its propagating materials of fungal infection, the plant of taking from natural life circulation and/or animal origin, use the present composition.
Claims (16)
1. preventing and treating the method that causes phytopathy venereal disease evil on the turfgrass or on its seed, it comprises to this turfgrass, its location or its seed uses composition, and said composition comprises at least a formula I compound of antifungal effective dose except that formulation auxiliary agents
Wherein A is
Or
Or the dynamic isomer of this compound.
2. the process of claim 1 wherein that this formula I compound is a formula IA compound
3. the process of claim 1 wherein that this formula I compound is a formula IB compound
4. the process of claim 1 wherein that said composition comprises from 0.01 to 90% by weight formula I compound, from 10 to 99.99% carrier and from 0 to 20% surfactant.
5. the method that causes phytopathy venereal disease evil of the control turfgrass of claim 1, wherein said composition is used to this turfgrass or to its location.
6. the method for claim 5, wherein said composition is used to turfgrass.
7. the method for claim 6, wherein this formula I compound is used with 10 to 2000g/ha amount.
8. the method for claim 6, wherein this formula I compound is used with 200 to 800g/ha amount.
9. the method for claim 5, wherein said composition is used to the location of this turfgrass.
Claim 1 cause the method for phytopathy venereal disease evil in control on the turfgrass or on its seed, wherein said composition is used to its seed.
11. the process of claim 1 wherein this cause phytopathy venereal disease evil be by one or more be selected from standing grain give birth to thorn dish spore, pythium, Rhizoctonia solani Kuhn, with domestic navel Helminthosporium, Marielliottia spp., bipolar Pseudomonas, Curvularia and the mould genus of bright navel in fruit stone cup fungi, gaeumannomyce bacterium, the rotten microtorr bacterium of snow, meat spore nuclear coral bacterium, the anti-rice blast fungus of marine microorganism to cause the plant characteristic of disease fungus-caused.
12. the process of claim 1 wherein that this causes phytopathy venereal disease evil is to give birth to thorn dish spore, Rhizoctonia solani Kuhn and cause the plant characteristic of disease with one or more of fruit stone cup fungi fungus-caused by being selected from standing grain.
13. the process of claim 1 wherein that this causes phytopathy venereal disease evil by causing with the fruit stone cup fungi.
14. the process of claim 1 wherein that this turfgrass is annual or perennial at least a grass family in Agropyron, Agrostis, carpetweed genus, Brome, buffalo grass, Cynodon, ciliate desert-grass genus, Festuca, Lolium, Paspalum, Pennisetum, ladder forage spp, annual bluegrass genus, Herba Stenotaphri helferi genus or each genus of Zoysia that belongs to.
15. preventing and treating the method that causes phytopathy venereal disease evil on the turfgrass or on its seed, it comprises to turfgrass, its location or its seed uses composition, said composition comprises active component except that formulation auxiliary agents, this active component is made up of the formula I compound of the claim 1 of antifungal effective dose or the dynamic isomer of this compound basically.
16. improve the turfgrass method for quality, it comprises to this turfgrass, its location or its seed uses composition, and said composition includes the formula I compound of the claim 1 of imitating the amount that increases the turfgrass quality or the dynamic isomer of this compound except that formulation auxiliary agents.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06007388 | 2006-04-07 | ||
| EP06007388.9 | 2006-04-07 | ||
| EP06007481 | 2006-04-10 | ||
| EP06007481.2 | 2006-04-10 | ||
| PCT/US2007/065843 WO2007118069A2 (en) | 2006-04-07 | 2007-04-03 | Method of controlling phytopathogenic diseases on turfgrass |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101415327A true CN101415327A (en) | 2009-04-22 |
| CN101415327B CN101415327B (en) | 2012-10-10 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2007800125433A Active CN101415327B (en) | 2006-04-07 | 2007-04-03 | Method of controlling phytopathogenic diseases on turfgrass |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN101415327B (en) |
| ZA (1) | ZA200808001B (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103947430A (en) * | 2014-05-09 | 2014-07-30 | 辽宁大学 | Novel water-saving mixed lawn cultivating method |
| CN104351173A (en) * | 2008-06-26 | 2015-02-18 | 森科能源公司 | Improved turfgrass fungicide formulation with pigment |
| US9357768B2 (en) | 2006-10-05 | 2016-06-07 | Suncor Energy Inc. | Herbicidal composition with increased herbicidal efficacy |
| US9750249B2 (en) | 2010-09-09 | 2017-09-05 | Suncor Energy Inc. | Synergistic paraffinic oil and boscalid fungicides |
| US9999219B2 (en) | 2004-05-18 | 2018-06-19 | Suncor Energy Inc. | Spray oil and method of use therof for controlling turfgrass pests |
| CN111684081A (en) * | 2018-02-05 | 2020-09-18 | 先正达参股股份有限公司 | Method for detecting fungi in turfgrass using LAMP assay with novel primer set |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105230642A (en) * | 2014-07-11 | 2016-01-13 | 深圳诺普信农化股份有限公司 | Bactericidal composition containing isopyrazam and application thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0224316D0 (en) * | 2002-10-18 | 2002-11-27 | Syngenta Participations Ag | Chemical compounds |
-
2007
- 2007-04-03 CN CN2007800125433A patent/CN101415327B/en active Active
-
2008
- 2008-09-17 ZA ZA200808001A patent/ZA200808001B/en unknown
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9999219B2 (en) | 2004-05-18 | 2018-06-19 | Suncor Energy Inc. | Spray oil and method of use therof for controlling turfgrass pests |
| US9357768B2 (en) | 2006-10-05 | 2016-06-07 | Suncor Energy Inc. | Herbicidal composition with increased herbicidal efficacy |
| US9801369B2 (en) | 2006-10-05 | 2017-10-31 | Suncor Energy Inc. | Herbicidal composition with increased herbicidal efficacy |
| CN104351173A (en) * | 2008-06-26 | 2015-02-18 | 森科能源公司 | Improved turfgrass fungicide formulation with pigment |
| US9826738B2 (en) | 2008-06-26 | 2017-11-28 | Suncor Energy Inc. | Turfgrass fungicide formulation with pigment |
| US9750249B2 (en) | 2010-09-09 | 2017-09-05 | Suncor Energy Inc. | Synergistic paraffinic oil and boscalid fungicides |
| CN103947430A (en) * | 2014-05-09 | 2014-07-30 | 辽宁大学 | Novel water-saving mixed lawn cultivating method |
| CN111684081A (en) * | 2018-02-05 | 2020-09-18 | 先正达参股股份有限公司 | Method for detecting fungi in turfgrass using LAMP assay with novel primer set |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200808001B (en) | 2009-11-25 |
| CN101415327B (en) | 2012-10-10 |
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