CN103238601A - Bactericidal composition containing fluazinam and zoxamide - Google Patents
Bactericidal composition containing fluazinam and zoxamide Download PDFInfo
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Abstract
The invention relate to a bactericidal composition containing fluazinam and zoxamide. Active components of the bactericidal composition comprise fluazinam and zoxamide, wherein a weight ratio of fluazinam to zoxamide is 1 : 60-60 : 1; the active components are made into wettable powder, water dispersible granules, suspensions, suspension emulsions, emulsions in water and microemulsions by adding auxiliary agents, and are used for preventing and treating powdery mildew, fusarium wilt, downy mildew, gray mold, phytophthora disease, anthracnose, ring rot disease, sheath blight and alternaria leaf spot. The bactericidal composition has wide bacteriocidal spectrum and small dosage, is resistant to rain wash, and has obvious synergy.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of bactericidal composition on crop pest that contains fluazinam and zoxamide.
Technical background
Fluazinam, English name: Zoxamide, molecular formula: C
14H
16Cl
3NO
2, chemical name: 3,5-two chloro-N-(3-chloro-1-ethyl-1-methyl-2-oxygen propyl group)-4-methyl benzamide.Fluazinam suppresses the cell nucleus division.With use on the market other prevent and treat Oomycete disease medicament and do not have cross resistance.Prevention or treatment target: by the microbial disease of Oomycete cause of disease such as cucumber downy mildew, downy mildew of garpe, potato and tomato late blight etc.Other disease such as gray mold etc. also there is certain activity.
Zoxamide, English name: Fluazinam, molecular formula: C
13H
4Cl
2F
6N
4O
4, chemical name: 3-chloro-N-(3-chloro-5-trifluoromethyl-2-pyridine radicals)-a, a, a-three fluoro-2,6-dinitro-right-toluidines.Zoxamide gives sprouting, mycelia breakthrough, growth and sporulation by the inhibition spore and suppresses the course of infection in all stages.The fungicidal spectrum of zoxamide is very wide, and its effect is better than the GPF (General Protection False bactericide.For example very effective to interlink spore genus, Botrytis, Phytophthora, Plasmopara, Sclerotinia and Venturia bacterium, the Botrytis cinerea of anti-benzimidazole type and dicarboximide class biocide agent also there is good result.Resistance of rainwater washing against, the lasting period is long, has the effect of good control phytophagous mites concurrently, the crucifer club root is also had remarkable preventive effect, to by the microbial paddy rice damping off of head mold fine preventive effect being arranged also.
In the real process of agricultural production, preventing and treating the problem that disease is easy to generate most is the drug-fast generation of germ.The different cultivars composition carries out composite, is to prevent and treat the very common method of resistance germ.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals all is additive effect, and the seldom composite of synergistic effect really arranged, especially synergistic effect very obviously, synergy ratio very high composite just still less.Through inventor research, find fluazinam and zoxamide is composite mutually, good synergistic effect is arranged within the specific limits, and relevant composite about fluazinam and zoxamide, do not see relevant report at present at home and abroad as yet.
Summary of the invention
The objective of the invention is to propose a kind of have synergistic function, use cost is low, preventive effect the is good bactericidal composition that contains fluazinam and zoxamide.
The present invention is achieved through the following technical solutions:
A kind of bactericidal composition that contains fluazinam and zoxamide is characterized in that: the weight ratio of effective active composition fluazinam and zoxamide is 1: 60～60: 1.
The described bactericidal composition that contains fluazinam and zoxamide is characterized in that: the weight ratio of fluazinam and zoxamide is 1: 40～30: 1.
The described bactericidal composition that contains fluazinam and zoxamide is characterized in that: the weight ratio of fluazinam and zoxamide is 1: 20～10: 1.
The described bactericidal composition that contains fluazinam and zoxamide is made wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion.
The described bactericidal composition that contains fluazinam and zoxamide, the disease that is used for preventing and treating grass family class crop, vegetables, fruit tree.
Described disease comprises powdery mildew, fusarium wilt, downy mildew, gray mold, eqpidemic disease, anthracnose, ring spot, banded sclerotial blight, spot defoliation.
Amount of application when the content of active component depends on independent use in the present composition also depends on mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, and the while is also relevant with the target fungi.Usually active weight percentage is 0.5%～90% of gross weight in the composition, and preferable is 5%～85%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1%～70% active substance by weight, preferably is 5%～60%.
At least contain a kind of surfactant in the bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5%～30% of total formulation weight amount, and surplus is liquid diluent.
The selected surfactant of bactericidal composition of the present invention is known in those skilled in the art: can be selected from dispersant, wetting agent, thickener or the defoamer one or more.According to different dosage form, can also contain stabilizing agent known in those skilled in the art, antifreeze etc. in the preparation.
Bactericidal composition of the present invention can be processed into acceptable forms on any agricultural chemicals on demand.Wherein preferred dosage form is wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion.
When making wetting powder, composition comprises following constituent content: fluazinam 1～60%, zoxamide 1～60%, dispersant 5～10%, wetting agent 2～10%, filler surplus.
The former medicine of fluazinam, the former medicine of zoxamide, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, namely can be made into the wetting powder product of the present composition.
When making water dispersible granules, composition comprises following constituent content: fluazinam 1～60%, zoxamide 1～60%, dispersant 3～12%, wetting agent 1～8%, disintegrant 1～10%, binding agent 1～8%, filler surplus.
The former medicine of fluazinam, the former medicine of zoxamide, dispersant, wetting agent, disintegrant, filler etc. are pulverized the particle diameter that obtains needs through air-flow together, add other auxiliary agents such as binding agent again, obtain the materials of granulating.It is interior through after granulation and the drying to expect that product are quantitatively sent the fluidized bed granulation dryer to, makes the water dispersible granules product of the present composition.
When making suspending agent, composition comprises following constituent content: fluazinam 1～60%, zoxamide 1～60%, dispersant 2～10%, wetting agent 2～10%, defoamer 0.1～1%, thickener 0.1～2%, antifreeze 0.1～8%, stabilizing agent 0.05～3%, deionized water adds to 100%.
Dispersant, wetting agent, defoamer, thickener, antifreeze in the above-mentioned formulation material are mixed through high speed shear, add the former medicine of fluazinam, the former medicine of zoxamide, ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make the suspending agent product of the present composition.
Comprise following constituent content when composition is made suspension emulsion: fluazinam 1%～40%, zoxamide 1%～40%, emulsifier 2%～10%, dispersant 2%～10%, defoamer 0.1%～2%, thickener 0.1%～2%, antifreeze 0.1%～8%, stabilizing agent 0.05%～3%, water add to 100%.
Dispersant, defoamer, thickener, antifreeze, stabilizing agent in the above-mentioned prescription are mixed through high speed shear, add the former medicine of fluazinam, ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make the fluazinam suspending agent, then with the former medicine of zoxamide, emulsifier and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, make the suspension emulsion product of the present composition.
When making aqueous emulsion, composition comprises following constituent content: fluazinam 1%～40%, zoxamide 1%～40%, solvent 2%～10%, emulsifier 2%～12%, dispersant 2%～10%, co-emulsifier 0.2%～5%, antifreeze 0.1%～8%, defoamer 0.1%～2%, thickener 0.1%～2%, deionized water adds to 100%.
Be dissolved into even oil phase with having former medicine, solvent, emulsifier, co-emulsifier to be added together in the above-mentioned prescription, making.With deionized water, dispersant, antifreeze,, defoamer, thickener mix, and becomes the homogeneous water, under high-speed stirred, water slowly splashed into oil phase, makes the finely disseminated aqueous emulsion product of the present composition.
When making microemulsion, composition comprises following constituent content: fluazinam 1%～40%, zoxamide 1%～40%, emulsifier 5%～15%, and solvent 2%～10%, antifreeze 5%～10%, stabilizing agent 0.5%～3%, deionized water adds to 100%.
Above-mentioned prescription Central Plains medicine, solvent, emulsifier are added in the mother liquor modulation kettle, make even oil phase, deionized water, antifreeze etc. is mixed injection product modulation kettle, through high-speed stirred, mix and make the transparent or semitransparent microemulsion product of the present composition.
Beneficial effect of the present invention: (1) present composition has good synergistic effect within the specific limits, and preventive effect is higher than single agent, and dosage is little; (2) organic solvent usage amount of the present invention is little, is difficult for producing poisoning, is convenient to transportation and storage; (3) present composition has enlarged fungicidal spectrum, and crop powdery mildew, fusarium wilt, downy mildew, eqpidemic disease, anthracnose, ring spot, banded sclerotial blight, spot defoliation are all had special efficacy.
Embodiment
Below in conjunction with the further instruction of the present invention of embodiment, the percentage among the embodiment is weight ratio, but the present invention is not limited thereto.
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.
Application Example one
Example 16 1% fluazinam zoxamide wetting powders
Fluazinam 1%, zoxamide 60%, octylphenol polyethylene oxyethylene group ether sulfate 6%, spaonin powder 7%, diatomite add to 100%, and mixture carries out air-flow to be pulverized, and makes 61% fluazinam zoxamide wetting powder.
Example 2 40% fluazinam zoxamide wetting powders
Fluazinam 10%, zoxamide 30%, alkylphenol-polyethenoxy are phonetic 5%, sldium lauryl sulfate 6%, bentonite add to 100%, and mixture carries out air-flow to be pulverized, and makes 40% fluazinam zoxamide wetting powder.
Example 3 60% fluazinam zoxamide wetting powders
Fluazinam 20%, zoxamide 40%, ester polyoxyethylene are phonetic 8%, sldium lauryl sulfate 5%, diatomite add to 100%, and mixture carries out air-flow to be pulverized, and makes 60% fluazinam zoxamide wetting powder.
Example 4 70% fluazinam zoxamide wetting powders
Fluazinam 10%, zoxamide 60%, polyoxyethylene carboxylate 7%, spaonin powder 6%, precipitated calcium carbonate add to 100%, and mixture carries out air-flow to be pulverized, and mixture carries out air-flow to be pulverized, and makes 70% fluazinam zoxamide wetting powder.
Example 5 50% fluazinam zoxamide wetting powders
Fluazinam 25%, zoxamide 25%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 8%, wetting and penetrating agent F 7%, precipitated calcium carbonate add to 100%, and mixture carries out air-flow to be pulverized, and makes 50% fluazinam zoxamide wetting powder.
Example 6 70% fluazinam zoxamide wetting powders
Fluazinam 40%, zoxamide 30%, alkylaryl APEO 9%, wetting and penetrating agent F 5%, spaonin powder add to 100%, and mixture carries out air-flow to be pulverized, and makes 70% fluazinam zoxamide wetting powder.
Example 7 25% fluazinam zoxamide water dispersible granules
Fluazinam 5%, zoxamide 20%, lignosulfonates 7%, lauryl sodium sulfate 4%, sodium bicarbonate 3%, precipitated calcium carbonate add to 100%, the mixed 25% fluazinam zoxamide water dispersible granules that gets.
Example 8 60% fluazinam zoxamide water dispersible granules
Fluazinam 20%, zoxamide 40%, polycarboxylate 9%, silkworm excrement 6%, bentonite 2.5%, attapulgite add to 100%, the mixed 60% fluazinam zoxamide water dispersible granules that gets.
Example 9 40% fluazinam zoxamide water dispersible granules
Fluazinam 10%, zoxamide 30%, alkylphenol-polyethenoxy are phonetic 8%, Nekal BX 3%, bentonite 4%, precipitated calcium carbonate add to 100%, mixed 40% fluazinam zoxamide water dispersible granules.
Example 10 30% fluazinam zoxamide water dispersible granules
Fluazinam 15%, zoxamide 15%, polyoxyethylene carboxylate 6%, tea are withered 5%, sodium bicarbonate 4%, precipitated calcium carbonate add to 100%, mixed 30% fluazinam zoxamide water dispersible granules.
Example 11 61% fluazinam zoxamide water dispersible granules
Fluazinam 60%, zoxamide 1%, alkylphenol-polyethenoxy are phonetic 6%, spaonin powder 5%, urea 4%, white carbon add to 100%, mixed 61% fluazinam zoxamide water dispersible granules.
Example 12 40% fluazinam zoxamide suspending agents
Fluazinam 15%, zoxamide 25%, ester polyoxyethylene are phonetic 8%, sldium lauryl sulfate 5%, silicone compound 0.2%, CMC 0.9%, ethylene glycol 2.8%, deionized water add to 100%, mixed 40% fluazinam zoxamide suspending agent.
Example 13 60% fluazinam zoxamide suspending agents
Fluazinam 20%, zoxamide 40%, alkylnaphthalene sulfonate 5%, wetting and penetrating agent F 6%, C
8～10Aliphatic alcohols 0.3%, xanthans 1.2%, diethylene glycol (DEG) 2%, deionized water add to 100%, the mixed 60% fluazinam zoxamide suspending agent that gets.
Example 14 40% fluazinam zoxamide suspending agents
Fluazinam 20%, zoxamide 20%, ester polyoxyethylene are phonetic 7%, Nekal BX 3%, capric acid 0.3%, Magnesiumaluminumsilicate 0.8%, polyethylene glycol 2.5%, deionized water add to 100%, mixed 40% fluazinam zoxamide suspending agent.
Example 15 45% fluazinam zoxamide suspending agents
Fluazinam 25%, zoxamide 20%, octylphenol polyethylene oxyethylene group ether sulfate 6%, lauryl sodium sulfate 3%, silicone oil 0.3%, melon glue 0.6%, polyvinyl alcohol 2.7%, deionized water add to 100%, the mixed 45% fluazinam zoxamide suspending agent that gets.
Example 16 38% fluazinam zoxamide suspending agents
Fluazinam 30%, zoxamide 8%, aryl phenol polyoxyethylene succinate sulfonate 7%, silkworm excrement 4%, silicone 0.3%, CMC 0.7%, xanthans 2.5%, deionized water add to 100%, the mixed 38% fluazinam zoxamide suspending agent that gets.
Example 17 65% fluazinam zoxamide suspending agents
Fluazinam 35%, zoxamide 30%, octylphenol polyethylene oxyethylene group ether sulfate 7%, wetting and penetrating agent F 4%, silicone oil 0.3%, Magnesiumaluminumsilicate 0.7%, polyvinylpyrrolidone 2.4%, deionized water add to 100%, the mixed 65% fluazinam zoxamide suspending agent that gets.
Example 18 30% fluazinam zoxamide suspension emulsions
Fluazinam 15%, zoxamide 15%, the phonetic formaldehyde condensation products sulphate 7% of alkylphenol-polyethenoxy, wetting and penetrating agent F 6%, PAA 0.6%, tween series 4%, propane diols 2%, silicone 0.3%, water add to 100%, through the mixed 30% fluazinam zoxamide suspension emulsion that gets.
Example 19 35% fluazinam zoxamide suspension emulsions
Fluazinam 15%, zoxamide 20%, polycarboxylate 7%, Nekal BX 3%, xanthans 1.4%, castor oil polyoxyethylene ether 5%, triethylene glycol 2.5%, silicone oil 0.3%, water add to 100%, through the mixed 35% fluazinam zoxamide suspension emulsion that gets.
Example 20 45% fluazinam zoxamide suspension emulsions
Fluazinam 15%, zoxamide 30%, alkylaryl APEO 4%, soapberry powder 5%, sodium phosphate trimer 0.6%, polyvinyl alcohol 2.5%, silicone compound 0.3%, fatty alcohol-polyoxyethylene ether 7%, water add to 100%, the mixed 45% fluazinam zoxamide suspension emulsion that gets.
Example 21 60% fluazinam zoxamide suspension emulsions
Fluazinam 20%, zoxamide 40%, the phonetic formaldehyde condensation products sulphate 6% of alkylphenol-polyethenoxy, spaonin powder 5%, sodium phosphate trimer 0.7%, PAA 2.2%, silicone 0.4%, fatty alcohol-polyoxyethylene ether 7%, water add to 100%, the mixed 60% fluazinam zoxamide suspension emulsion that gets.
Example 22 41% fluazinam zoxamide suspension emulsions
Fluazinam 40%, zoxamide 1%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 7%, silkworm excrement 5%, methylcellulose 0.8%, polyethylene glycol 2.4%, silicone oil 0.4%, alkylaryl polyoxyethylene poly-oxygen propylene aether 8%, water add to 100%, the mixed 41% fluazinam zoxamide suspension emulsion that gets.
Example 23 10% fluazinam zoxamides alcohol aqueous emulsion
Fluazinam 1%, zoxamide 9%, propyl alcohol 6%, vegetable oil 5%, sorbitan fatty acid ester APEO 6%, diethylene glycol (DEG) 2.2%, silicone oil 0.3%, deionized water adds to 100%, the mixed 10% fluazinam zoxamide alcohol aqueous emulsion that gets.
Example 24 28% fluazinam zoxamide aqueous emulsions
Fluazinam 8%, zoxamide 20%, cyclohexanone 5%, butanols 3%, alkyl benzene calcium sulfonate 6%, glycerine 2.4%, silicone 0.6%, deionized water adds to 100%, through the mixed 28% fluazinam zoxamide aqueous emulsion that gets.
Example 25 45% fluazinam zoxamide aqueous emulsions
Fluazinam 15%, zoxamide 30%, N, dinethylformamide 7%, methyl alcohol 3%, phenethyl fluosite polyoxy ethyl ether 5%, polyethylene glycol 2%, C
8～10Aliphatic alcohols 0.2%, deionized water adds to 100%, through the mixed 45% fluazinam zoxamide aqueous emulsion that gets.
Example 26 35% fluazinam zoxamides alcohol aqueous emulsion
Fluazinam 30%, zoxamide 5%, toluene 5%, ethyl acetate 3%, sorbitan monostearate 4%, diethylene glycol (DEG) 2.2%, silicone oil 0.3%, deionized water adds to 100%, the mixed 35% fluazinam zoxamide alcohol aqueous emulsion that gets.
Example 27 65% fluazinam zoxamide aqueous emulsions
Fluazinam 35%, zoxamide 30%, propyl alcohol 5%, ethylene glycol monomethyl ether 3%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 7%, propane diols 2.4%, silicone 0.5%, deionized water adds to 100%, through the mixed 65% fluazinam zoxamide aqueous emulsion that gets.
Example 28 53% fluazinam zoxamide aqueous emulsions
Fluazinam 13%, zoxamide 40%, N, dinethylformamide 9%, butyl ether 3%, polyoxyethylene nonylphenol ether 5%, triethylene glycol 2%, silicone compound 0.2%, deionized water adds to 100%, through the mixed 53% fluazinam zoxamide aqueous emulsion that gets.
Example 29 18% fluazinam zoxamide microemulsions
Fluazinam 8%, zoxamide 10%, butyl ether 5%, acetonitrile 4%, sorbitan monostearate 8%, ethylene glycol 2%, C
8～10Aliphatic alcohols 0.4%, deionized water adds to 100%, the mixed 18% fluazinam zoxamide microemulsion that gets.
Example 30 36% fluazinam zoxamide microemulsions
Fluazinam 12%, zoxamide 24%, butanols 5%, N, dinethylformamide 5%, sorbitan monostearate 6%, gum Arabic 2.5%, silicone oil 0.4%, deionized water adds to 100%, through the mixed 36% fluazinam zoxamide microemulsion that gets.
Example 31 50% fluazinam zoxamide microemulsions
Fluazinam 25%, zoxamide 25%, propyl alcohol 5%, N-pyrrolidones 4%, benzyl dimethyl phenol polyoxy ethyl ether 6%, polyethylene glycol 3%, silicone 0.2%, deionized water adds to 100%, through the mixed 50% fluazinam zoxamide microemulsion that gets.
Example 32 30% fluazinam zoxamide microemulsions
Fluazinam 10%, zoxamide 20%, vegetable oil 3%, butyl ether 2%, phenethyl phenol polyoxy ethyl polypropylene-base ether 10%, ethylene glycol 3%, silicone compound 0.2%, deionized water adds to 100%, the mixed 30% fluazinam zoxamide microemulsion that gets.
Example 33 48% fluazinam zoxamide microemulsions
Fluazinam 30%, zoxamide 18%, N-pyrrolidones 5%, ethylene glycol monomethyl ether 5%, castor oil polyoxyethylene ether 6%, ethylene glycol 2.4%, silicone 0.5%, deionized water adds to 100%, through the mixed 48% fluazinam zoxamide microemulsion that gets.
Example 34 37% fluazinam zoxamide microemulsions
Fluazinam 24%, zoxamide 13%, cyclohexanone 4%, toluene 5%, polyoxyethylene nonylphenol ether phosphate 5%, propane diols 4%, silicone oil 0.3%, deionized water adds to 100%,
Through the mixed 37% fluazinam zoxamide microemulsion that gets.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.Earlier by Toxicity Determination, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR＜0.5 is antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect, on this basis, carry out field trial again.
Fluazinam and zoxamide are composite to the crop pest Toxicity Determination.
After the effective inhibition concentration scope of each medicament was determined in prerun, medicament was established 5 dosage respectively by active constituent content and is handled, and established the clear water contrast.Carry out with reference to " agricultural chemicals indoor bioassay test rule bactericide ", adopt the mycelial growth rate method to measure medicament to the virulence of crop germ.Measure colony diameter with the right-angled intersection method behind the 72h, calculate and respectively handle clean amount of growth, mycelial growth inhibition rate.
Clean amount of growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, tries to achieve virulence regression equation (y=a+bx) with method of least squares, and calculates the EC of every kind of medicament thus
50Value.Calculate the different proportioning synergy ratios (SR) of two medicaments according to the Wadley method simultaneously, SR＜0.5 is antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active component fluazinam and zoxamide shared ratio in combination;
A is fluazinam;
B is zoxamide.
Implementation of an application example two:
Fluazinam and zoxamide are composite to the cucumber downy mildew Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining fluazinam, the former medicine of zoxamide and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 1 fluazinam, the composite toxicity test analysis of results table to cucumber downy mildew of zoxamide
As shown in Table 1, fluazinam, zoxamide are to the EC of cucumber downy mildew
50Be respectively 0.39mg/L and 0.77mg/L.Fluazinam and zoxamide proportioning were at 60: 1 to 1: 60 o'clock, synergy ratio SR is all greater than 1.5, illustrating that fluazinam and zoxamide were mixed in the scope at 60: 1 to 1: 60 all shows synergistic effect, especially when the two proportioning during at 5: 1 to 1: 5, synergistic effect is more obviously outstanding, synergy ratio SR maximum when fluazinam and zoxamide weight ratio are 1: 2 wherein, synergistic effect is the most obvious, test is found, when the proportioning of fluazinam and zoxamide at 10: 1,9: 1,8: 1,7: 1,6: 1,5: 1,4: 1,3: 1,2: 1,1: 1,1: 2,1: 3,1: 4,1: 5,1: 6,1: 7,1: 8,1: 9,1: 10,1: 11,1: 12,1: 13,1: 14,1: 15,1: 16,1: 17,1: 18,1: 19,1: 20 o'clock to powdery mildew, fusarium wilt, downy mildew, gray mold, eqpidemic disease, anthracnose, ring spot, banded sclerotial blight, spot defoliation, synergistic effect is obvious, and synergy ratio is all greater than 1.5.
Application Example three fluazinams and zoxamide and the composite control graw mold of tomato test of pesticide effectiveness thereof
This experimental establishment is at Baoji, Shaanxi province city Chencang District, test medicine is researched and developed, is provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 500 grams per liter fluazinam suspending agents (commercial Japanese Ishihara Sangyo Kaisha, Ltd.), 24% zoxamide suspending agent (preparation of Shaanxi research and development department of agricultural chemicals Co., Ltd of U.S. nation).
The investigation graw mold of tomato state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 3 days, 7 days, 14 days after the dispenser for the second time.Experimental result is as follows:
Table 2 fluazinam, zoxamide and the composite control graw mold of tomato test of pesticide effectiveness thereof
As can be seen from Table 2, can effectively prevent and treat graw mold of tomato after fluazinam and zoxamide are composite, control efficiency all is better than the preventive effect of single agent, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example four fluazinams and zoxamide and the composite control tomato late blight test of pesticide effectiveness thereof
This experimental establishment is at Baoji, Shaanxi province city Chencang District, test medicine is researched and developed, is provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 500 grams per liter fluazinam suspending agents (commercial Japanese Ishihara Sangyo Kaisha, Ltd.), 24% zoxamide suspending agent (preparation of Shaanxi research and development department of agricultural chemicals Co., Ltd of U.S. nation).
The investigation tomato late blight state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 3 days, 7 days, 14 days after the dispenser for the second time.Experimental result is as follows:
Table 3 fluazinam, zoxamide and the composite control tomato late blight test of pesticide effectiveness thereof
As can be seen from Table 3, can effectively prevent and treat tomato late blight after fluazinam and zoxamide are composite, control efficiency all is better than the preventive effect of single agent, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example five fluazinams and zoxamide and the composite control pepper anthracnose test of pesticide effectiveness thereof
This experimental establishment is at the Xian City, Shanxi Province Changan District, test medicine is researched and developed, is provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 500 grams per liter fluazinam suspending agents (commercial Japanese Ishihara Sangyo Kaisha, Ltd.), 24% zoxamide suspending agent (preparation of Shaanxi research and development department of agricultural chemicals Co., Ltd of U.S. nation).
The investigation pepper anthracnose state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 3 times.Investigated disease index respectively and calculated preventive effect in 3 days, 7 days, 14 days after the dispenser for the third time.Experimental result is as follows:
Table 4 fluazinam, zoxamide and the composite control pepper anthracnose test of pesticide effectiveness thereof
As can be seen from Table 4, can effectively prevent and treat pepper anthracnose after fluazinam and zoxamide are composite, control efficiency all is better than the preventive effect of single agent, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
After draw through different local throughout the country tests, the preventive effect of common diseases such as the composite back banded sclerotial blight to all kinds of crops of fluazinam and zoxamide, powdery mildew, fusarium wilt, downy mildew, eqpidemic disease, anthracnose, ring spot, banded sclerotial blight, spot defoliation is all more than 95%, be better than single agent preventive effect, synergistic effect is obvious.
Claims (7)
1. bactericidal composition that contains fluazinam and zoxamide, it is characterized in that: the weight ratio of effective active composition fluazinam and zoxamide is 1: 60～60: 1.
2. a kind of bactericidal composition that contains fluazinam and zoxamide according to claim 1, it is characterized in that: the weight ratio of fluazinam and zoxamide is 1: 40～30: 1.
3. a kind of bactericidal composition that contains fluazinam and zoxamide according to claim 2, it is characterized in that: the weight ratio of fluazinam and zoxamide is 1: 20～10: 1.
4. microbicide compositions according to claim 1, its active ingredient total content is 0.5%～90%.
5. a kind of bactericidal composition that contains fluazinam and zoxamide according to claim 1, it is characterized in that: the formulation of microbicide compositions is selected from wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion.
6. according to each the described a kind of bactericidal composition that contains fluazinam and zoxamide in the claim 1～5, be used for the application of disease on control grass family class crop, vegetables, the fruit tree.
7. application according to claim 6 is characterized in that: described disease comprises powdery mildew, fusarium wilt, downy mildew, gray mold, eqpidemic disease, anthracnose, ring spot, banded sclerotial blight, spot defoliation.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2012100245688A CN103238601A (en) | 2012-02-04 | 2012-02-04 | Bactericidal composition containing fluazinam and zoxamide |
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| CN2012100245688A CN103238601A (en) | 2012-02-04 | 2012-02-04 | Bactericidal composition containing fluazinam and zoxamide |
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| CN103238601A true CN103238601A (en) | 2013-08-14 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106035380A (en) * | 2016-06-27 | 2016-10-26 | 中国烟草总公司郑州烟草研究院 | Bactericide composition containing benzamide and dinitroaniline bactericides and biocontrol bacterium, preparation and applications |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1229580A (en) * | 1998-01-27 | 1999-09-29 | 罗姆和哈斯公司 | Fungicidal compositions containing N-acetonylbenzamides |
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2012
- 2012-02-04 CN CN2012100245688A patent/CN103238601A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1229580A (en) * | 1998-01-27 | 1999-09-29 | 罗姆和哈斯公司 | Fungicidal compositions containing N-acetonylbenzamides |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106035380A (en) * | 2016-06-27 | 2016-10-26 | 中国烟草总公司郑州烟草研究院 | Bactericide composition containing benzamide and dinitroaniline bactericides and biocontrol bacterium, preparation and applications |
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