CN101411822B - Kidney-tonifying Chinese medicinal formulation for treating diabetes and preparation method thereof - Google Patents
Kidney-tonifying Chinese medicinal formulation for treating diabetes and preparation method thereof Download PDFInfo
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- CN101411822B CN101411822B CN2008101834039A CN200810183403A CN101411822B CN 101411822 B CN101411822 B CN 101411822B CN 2008101834039 A CN2008101834039 A CN 2008101834039A CN 200810183403 A CN200810183403 A CN 200810183403A CN 101411822 B CN101411822 B CN 101411822B
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Abstract
The invention relates to a traditional Chinese medicine preparation for treating diabetes and a method for preparing the same, in particular to a kidney-tonifying traditional Chinese medicine preparation for treating the diabetes and the method for preparing the same. The technical proposal is as follows: (1) raw material selection, which is to select the traditional Chinese medicines of radix rehmanniae, rhizoma polygonati, ligustrum lacidum aiton, scrophulariaceae, dodder, and buckwheat whole plant, and wash and grind the raw materials into coarse powder; and (2) confecting and decocting the raw materials according to the percentage by weight, wherein the compositions of traditional Chinese medicine in weight percentage are: 15 to 20 percent of the radix rehmanniae, 15 to 25 percent of the rhizoma polygonati, 10 to 15 percent of the ligustrum lacidum aiton, 15 to 20 percent of the scrophulariaceae, 15 to 20 percent of the dodder, and 15 to 25 percent of the buckwheat whole plant; adding water into the mixture for decoction, and filtering, drying and grinding the mixture to be prepared into the kidney-tonifying traditional Chinese medicine preparation for treating the diabetes. The kidney-tonifying traditional Chinese medicine preparation for treating the diabetes has the characteristics of clear and definite curative effect, low cost, easy taking and the like, is made from commonly-used Chinese herbal medicines which make up the whole formulation with low cost, and has remarkable effect on the treatment of the diabetes.
Description
Affiliated technical field:
The present invention relates to a kind of Chinese medicine preparation that is used for the treatment of diabetes and preparation method thereof, particularly treat kidney-nourishing tcm drug preparation of diabetes and preparation method thereof.
Background technology:
Diabetes are metabolic diseases of a kind of multi-pathogenesis, characteristics be chronic hyperglycemia follow because of insulin secretion and (or) effect the defective sugar, fat and the protein metabolism disorder that cause.Along with the prolongation of diabetic duration, intravital metabolism disorder is controlled well and is corrected as can not get, will cause losing one's sight, multiple complications such as cardiovascular and cerebrovascular disease, renal failure, neuropathy, extremity gangrene so that amputation, stupor, in addition dead.Clinical practice Chinese medicine has its special advantages aspect treating diabetes, but clinical Chinese medicine selection face limitation, and kind is few, the costliness of price comparison simultaneously.
Summary of the invention:
The object of the invention provides a kind of kidney-nourishing tcm drug preparation for the treatment of diabetes and preparation method thereof, and curative effect is clear and definite, with low cost, taking convenience, solves the problems referred to above that exist in the background technology.
Technical scheme of the present invention is: the kidney-nourishing tcm drug preparation of treatment diabetes comprises Semen Fagopyri Esculenti herb, Rhizoma Polygonati, the Radix Rehmanniae, Fructus Ligustri Lucidi, Radix Scrophulariae, Semen Cuscutae, and the percentage by weight of each Chinese medicine component is: Radix Rehmanniae 15-20%, Rhizoma Polygonati 15-25%, Fructus Ligustri Lucidi 10-15%, Radix Scrophulariae 15-20%, Semen Cuscutae 15-20%, Semen Fagopyri Esculenti herb 15-25%.
Kidney-nourishing tcm drug preparation of treatment diabetes and preparation method thereof comprises following operation:
1. material choice is selected the Chinese medicine Radix Rehmanniae, Rhizoma Polygonati, Fructus Ligustri Lucidi, Radix Scrophulariae, Semen Cuscutae, Semen Fagopyri Esculenti herb, cleans, and breaks into coarser powder; 2. prepare by weight percentage and decoct, the percentage by weight of each Chinese medicinal components is as follows: Radix Rehmanniae 15-20%, Rhizoma Polygonati 15-25%, Fructus Ligustri Lucidi 10-15%, Radix Scrophulariae 15-20%, Semen Cuscutae 15-20%, Semen Fagopyri Esculenti herb 15-25%; Decoct with water, filter, dry, grind, make the kidney-nourishing tcm drug preparation of treatment diabetes.
The kidney-nourishing tcm drug preparation of treatment diabetes can be made capsule, tablet, powder or the like as required.
The present invention is the Radix Rehmanniae, Rhizoma Polygonati, Fructus Ligustri Lucidi, Radix Scrophulariae, Semen Cuscutae, Semen Fagopyri Esculenti herb compatibility, based on nourishing kidney, again with the compatible composition of Semen Fagopyri Esculenti herb of the buckwheat total flavone that contains a large amount of blood sugar reducing functions.
The taste large intestine channel is gone in the sweet cold of Semen Fagopyri Esculenti herb, the wide intestinal of sending down the abnormal ascending QI; Pharmacological research shows that buckwheat total flavone has tangible blood sugar lowering, blood fat reducing, improves effects such as carbohydrate tolerance.
The Rhizoma Polygonati sweet in the mouth is flat, boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.Modern pharmacological research shows the content that can significantly reduce myocardium lipofuscin and improves SOD activity in the liver; Can be significantly to the caused blood sugar increasing of antiadrenergic drug; Improve body's immunological function and promote DNA, RNA and proteinic synthesizing.
Radix Rehmanniae sweet and slightly bitter taste is cold in nature, replenishing kidney-YIN heat clearing away, removing heat from blood, hemostasis.Modern pharmacological research shows the effect that heart tonifying diuresis, blood pressure lowering are arranged; The hyperglycemia that can reduce euglycemia and cause by epinephrine, ammonium chloride; Has tangible immunological enhancement.
Fructus Ligustri Lucidi bitter in the mouth, sweet, property are flat.Nourishing the liver and kidney, black hair make eye bright.Modern pharmacological research shows that Fructus Ligustri Lucidi polysaccharide has significant immunological enhancement; Can reduce the hyperglycemia that normal mouse, alloxan, epinephrine, glucose cause.
Radix Scrophulariae sweet in the mouth, hardship, salty, cold nature.Modern pharmacological research show have resisting pathogenic microbes and neutralize a toxin, antiinflammatory action; The effect of blood sugar lowering is arranged.
Semen Cuscutae sweet in the mouth, warm in nature.Nourishing the liver and kidney, the controlling nocturnal emission with astringent drugs reducing urination, antiabortive, make eye bright antidiarrheal.Modern pharmacological research shows to have anti-cancer effect in vitro; The effect of antioxidation and raise immunity; Strengthen myocardial contraction; Antibacterial action.
Full side acts on a plurality of internal organs of whole body, system, is not single blood sugar lowering, but brings into play the purpose that integrally-regulated effect reaches the treatment type ii diabetes.
The present invention has characteristics such as curative effect is clear and definite, with low cost, taking convenience, and this medicine composition is Chinese herbal medicine commonly used, and it is low to form complete square Chinese herbal medicine cost, and treatment diabetes effect is remarkable.
The specific embodiment:
Below in conjunction with embodiment, the invention will be further described.
In an embodiment, the kidney-nourishing tcm drug preparation of treatment diabetes is selected the Chinese medicine Radix Rehmanniae, Rhizoma Polygonati, Fructus Ligustri Lucidi, Radix Scrophulariae, Semen Cuscutae, Semen Fagopyri Esculenti herb for use, cleans, and breaks into coarser powder.Prepare by weight percentage and decoct, the percentage by weight of each Chinese medicinal components is as follows: Radix Rehmanniae 15-20%, Rhizoma Polygonati 15-25%, Fructus Ligustri Lucidi 10-15%, Radix Scrophulariae 15-20%, Semen Cuscutae 15-20%, Semen Fagopyri Esculenti herb 15-25%.Add 4 times of decoctings and boiled 1 hour, filter cloth filters again, and medicinal residues are decocted with water filtration in 1 hour again, and merging filtrate is condensed into paste in the water-bath, puts on the plate glass, and is dry in 80 ℃ of baking boxs.Grind into fine powder, by 60 mesh sieves, weight incapsulates on demand, makes the capsule for tonifying kidney of treatment diabetes.
The present invention studies by rat experiment, obtains beyond thought therapeutic effect, obtains following Main Conclusions:
1. the present invention can significantly reduce blood glucose, the blood lipid level of diabetes rat, improves carbohydrate tolerance, improves insulin sensitivity.
2. the present invention can significantly improve diabetes rat general state and performance such as " three-many-one-little " symptom, and the high dose group effect is more obvious.
3. the present invention has protective effect to the damage of histoorgans such as diabetes rat liver, kidney, heart and eye, can resist the infection of diabetes body to antibacterial.
4. the present invention has good preventive and therapeutic effect to diabetes and complication thereof.
Claims (3)
1. kidney-nourishing tcm drug preparation for the treatment of diabetes, it is characterized in that crude drug is made up of Semen Fagopyri Esculenti herb, Rhizoma Polygonati, the Radix Rehmanniae, Fructus Ligustri Lucidi, Radix Scrophulariae, Semen Cuscutae, the percentage by weight of each Chinese medicine component is: Radix Rehmanniae 15-20%, Rhizoma Polygonati 15-25%, Fructus Ligustri Lucidi 10-15%, Radix Scrophulariae 15-20%, Semen Cuscutae 15-20%, Semen Fagopyri Esculenti herb 15-25%.
2. preparation method for the treatment of diabetes kidney-nourishing tcm drug preparation is characterized in that comprising following operation:
1. material choice is selected the Chinese medicine Radix Rehmanniae, Rhizoma Polygonati, Fructus Ligustri Lucidi, Radix Scrophulariae, Semen Cuscutae, Semen Fagopyri Esculenti herb, cleans, and breaks into coarser powder; 2. prepare by weight percentage and decoct, the percentage by weight of each Chinese medicinal components is as follows: Radix Rehmanniae 15-20%, Rhizoma Polygonati 15-25%, Fructus Ligustri Lucidi 10-15%, Radix Scrophulariae 15-20%, Semen Cuscutae 15-20%, Semen Fagopyri Esculenti herb 15-25%; Decoct with water, filter, dry, grind, make the smart kidney-nourishing tcm drug preparation of buckwheat of treatment diabetes.
3. the preparation method of treatment diabetes kidney-nourishing tcm drug preparation according to claim 2 is characterized in that adding 4 times of decoctings and boiled 1 hour, filters with filter cloth, medicinal residues are decocted with water filtration in 1 hour again, and merging filtrate is condensed into paste in the water-bath, put on the plate glass, dry in 80 ℃ of baking boxs; Grind into fine powder, by 60 mesh sieves, weight incapsulates on demand, makes the smart capsule for tonifying kidney of buckwheat.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101834039A CN101411822B (en) | 2008-12-16 | 2008-12-16 | Kidney-tonifying Chinese medicinal formulation for treating diabetes and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101834039A CN101411822B (en) | 2008-12-16 | 2008-12-16 | Kidney-tonifying Chinese medicinal formulation for treating diabetes and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101411822A CN101411822A (en) | 2009-04-22 |
| CN101411822B true CN101411822B (en) | 2011-09-07 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2008101834039A Expired - Fee Related CN101411822B (en) | 2008-12-16 | 2008-12-16 | Kidney-tonifying Chinese medicinal formulation for treating diabetes and preparation method thereof |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102960497A (en) * | 2012-12-18 | 2013-03-13 | 朱克兰 | Blood-sugar reducing, kidney invigorating and health caring tea |
| CN104887847A (en) * | 2015-06-16 | 2015-09-09 | 徐倩 | Traditional Chinese medicine composition for treating diabetes and preparation method of traditional Chinese medicine composition |
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2008
- 2008-12-16 CN CN2008101834039A patent/CN101411822B/en not_active Expired - Fee Related
Non-Patent Citations (2)
| Title |
|---|
| 古月.降脂降糖说荞麦.《东方食疗与保健》.2007,(第1期),10. * |
| 王巍.中医药治疗消渴的研究进展.《现代中西医结合杂志》.2008,第17卷(第6期),970. * |
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| CN101411822A (en) | 2009-04-22 |
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Granted publication date: 20110907 Termination date: 20121216 |