CN101389334A - 埃坡霉素d的给药方法 - Google Patents

埃坡霉素d的给药方法 Download PDF

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Publication number
CN101389334A
CN101389334A CNA03815062XA CN03815062A CN101389334A CN 101389334 A CN101389334 A CN 101389334A CN A03815062X A CNA03815062X A CN A03815062XA CN 03815062 A CN03815062 A CN 03815062A CN 101389334 A CN101389334 A CN 101389334A
Authority
CN
China
Prior art keywords
epothilone
experimenter
venoclysis
treatment cycle
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA03815062XA
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English (en)
Chinese (zh)
Inventor
R·G·小约翰逊
M·谢里尔
A·汉南
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kosan Biosciences Inc
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Kosan Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kosan Biosciences Inc filed Critical Kosan Biosciences Inc
Publication of CN101389334A publication Critical patent/CN101389334A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CNA03815062XA 2002-05-20 2003-05-20 埃坡霉素d的给药方法 Pending CN101389334A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38216602P 2002-05-20 2002-05-20
US60/382,166 2002-05-20

Publications (1)

Publication Number Publication Date
CN101389334A true CN101389334A (zh) 2009-03-18

Family

ID=33476529

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA03815062XA Pending CN101389334A (zh) 2002-05-20 2003-05-20 埃坡霉素d的给药方法

Country Status (7)

Country Link
US (1) US20040072882A1 (https=)
EP (1) EP1575556A2 (https=)
JP (1) JP2006514681A (https=)
KR (1) KR20050043796A (https=)
CN (1) CN101389334A (https=)
AU (1) AU2003296878A1 (https=)
WO (1) WO2004103267A2 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999001124A1 (en) * 1996-12-03 1999-01-14 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto, analogues and uses thereof
US20020058286A1 (en) * 1999-02-24 2002-05-16 Danishefsky Samuel J. Synthesis of epothilones, intermediates thereto and analogues thereof
US8618085B2 (en) * 2000-04-28 2013-12-31 Koasn Biosciences Incorporated Therapeutic formulations of desoxyepothilones
US7649006B2 (en) 2002-08-23 2010-01-19 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
DE60330407D1 (de) * 2002-08-23 2010-01-14 Sloan Kettering Inst Cancer Synthese von Epothilonen, Zwischenprodukte davon, Analoga und ihre Verwendung
US6921769B2 (en) 2002-08-23 2005-07-26 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
AU2004268377B2 (en) * 2003-09-02 2008-06-26 Novartis Ag Cancer treatment with epothilones
US20050171167A1 (en) * 2003-11-04 2005-08-04 Haby Thomas A. Process and formulation containing epothilones and analogs thereof
US20050215604A1 (en) * 2004-03-26 2005-09-29 Kosan Biosciences, Inc. Combination therapies with epothilones and carboplatin
EP2634252B1 (en) 2005-02-11 2018-12-19 University of Southern California Method of expressing proteins with disulfide bridges
US8008256B2 (en) * 2006-05-01 2011-08-30 University Of Southern California Combination therapy for treatment of cancer
JP5718808B2 (ja) * 2008-04-25 2015-05-13 エーエスエム インターナショナル エヌ．ヴェー．Ａｓｍ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｎ．Ｖ． テルルおよびセレン薄膜のａｌｄのための前駆体の合成および使用
WO2010056901A2 (en) 2008-11-13 2010-05-20 University Of Southern California Method of expressing proteins with disulfide bridges with enhanced yields and activity
JP5731519B2 (ja) 2009-10-26 2015-06-10 エーエスエム インターナショナル エヌ．ヴェー．Ａｓｍ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｎ．Ｖ． Ｖａ族元素を含む薄膜のａｌｄのための前駆体の合成及び使用
AU2011255647A1 (en) 2010-05-18 2012-11-15 Cerulean Pharma Inc. Compositions and methods for treatment of autoimmune and other diseases

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69735057T2 (de) * 1996-03-12 2006-08-31 PG-TXL Co., L.P., Houston Wasserlösliche paclitaxel-prodrogen
WO1999001124A1 (en) * 1996-12-03 1999-01-14 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto, analogues and uses thereof
KR100574454B1 (ko) * 1997-12-04 2006-04-27 브리스톨-마이어즈 스퀴브 컴페니 옥시라닐 에포틸론을 환원시켜 올레핀계 에포틸론을 제조하는 방법
US6194181B1 (en) * 1998-02-19 2001-02-27 Novartis Ag Fermentative preparation process for and crystal forms of cytostatics
US6302838B1 (en) * 1998-02-25 2001-10-16 Novartis Ag Cancer treatment with epothilones
NZ511722A (en) * 1998-11-20 2004-05-28 Kosan Biosciences Inc Recombinant methods and materials for producing epothilone and epothilone derivatives
US6664288B1 (en) * 1999-04-14 2003-12-16 Dana Farber Cancer Institute, Inc. Method and composition for the treatment of cancer
CA2401800A1 (en) * 2000-03-01 2001-09-07 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
EP1652926B1 (en) * 2000-04-28 2009-09-30 Kosan Biosciences, Inc. Crystalline epothilone d
EP1303615A2 (en) * 2000-07-25 2003-04-23 Kosan Biosciences, Inc. Fermentation process for epothilones

Also Published As

Publication number Publication date
AU2003296878A1 (en) 2004-12-13
US20040072882A1 (en) 2004-04-15
JP2006514681A (ja) 2006-05-11
AU2003296878A8 (en) 2009-01-08
WO2004103267A2 (en) 2004-12-02
EP1575556A2 (en) 2005-09-21
WO2004103267A3 (en) 2008-11-27
KR20050043796A (ko) 2005-05-11

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Open date: 20090318