CN101384270A - 用灭活的或非感染性的细菌制备物控制肠道炎症综合征 - Google Patents

用灭活的或非感染性的细菌制备物控制肠道炎症综合征 Download PDF

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Publication number
CN101384270A
CN101384270A CNA2006800532346A CN200680053234A CN101384270A CN 101384270 A CN101384270 A CN 101384270A CN A2006800532346 A CNA2006800532346 A CN A2006800532346A CN 200680053234 A CN200680053234 A CN 200680053234A CN 101384270 A CN101384270 A CN 101384270A
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CN
China
Prior art keywords
gram
positive
bacterium
mice
purposes
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Pending
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CNA2006800532346A
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English (en)
Chinese (zh)
Inventor
G·马沙尔
M·拉格朗迪
M·阿布哈桑尼
H·贝尔科维尔
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Institut Pasteur
Yissum Research Development Co of Hebrew University of Jerusalem
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Institut Pasteur
Yissum Research Development Co of Hebrew University of Jerusalem
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Publication of CN101384270A publication Critical patent/CN101384270A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36—Adaptation or attenuation of cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/32—Mycobacterium

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CNA2006800532346A 2005-12-21 2006-12-21 用灭活的或非感染性的细菌制备物控制肠道炎症综合征 Pending CN101384270A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA2,531,261 2005-12-21
CA002531261A CA2531261A1 (en) 2005-12-21 2005-12-21 Control of intestinal inflammatory syndromes with a preparation of killed or non infectious bacteria

Publications (1)

Publication Number Publication Date
CN101384270A true CN101384270A (zh) 2009-03-11

Family

ID=38175409

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2006800532346A Pending CN101384270A (zh) 2005-12-21 2006-12-21 用灭活的或非感染性的细菌制备物控制肠道炎症综合征

Country Status (10)

Country Link
US (1) US20090280146A1 (https=)
EP (1) EP1971352A2 (https=)
JP (1) JP2009520810A (https=)
KR (1) KR20080092384A (https=)
CN (1) CN101384270A (https=)
AU (1) AU2006327761A1 (https=)
CA (2) CA2531261A1 (https=)
IL (1) IL192048A0 (https=)
MX (1) MX2008008157A (https=)
WO (1) WO2007072230A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105797145A (zh) * 2010-07-26 2016-07-27 Qu生物制药公司 免疫原性抗炎组合物

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2087898A1 (en) * 2008-02-06 2009-08-12 Institut Pasteur A preparation of mycobacterium bovis BCG killed by extended freeze drying (EFD) for treating rheumatoid arthritis
CA2629057A1 (en) * 2008-04-14 2009-10-14 Institut Pasteur Control of diseases associated with decrease of t-regulatory cells with a preparation of extended freeze-dried killed bacteria
EP2292260A1 (en) 2009-08-13 2011-03-09 Institut Pasteur Use of mycobacterium bovis BCG killed by extended freeze drying (EFD) for preventing or treating atherosclerosis
WO2013004069A1 (zh) * 2011-07-05 2013-01-10 苏州科景生物医药科技有限公司 沙门氏菌鞭毛蛋白衍生物在制备防治炎症性肠病药物中的应用
US9886742B2 (en) 2016-03-17 2018-02-06 Google Llc Electro-optic beam steering for super-resolution/lightfield imagery

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR012304A1 (es) * 1997-04-01 2000-10-18 Borody Thomas J Composiciones y metodos para el tratamiento de enfermedades intestinales inflamatorias y el uso de dicha composicion para preparar medicamentos paradichos tratamientos.
WO1998047520A1 (en) * 1997-04-24 1998-10-29 Lovelace Respiratory Research Institute Prevention and treatment of allergic disease by targeted development of protective t-helper lymphocyte immunity
AUPQ776100A0 (en) * 2000-05-26 2000-06-15 Australian National University, The Synthetic molecules and uses therefor
GB0106987D0 (en) * 2001-03-20 2001-05-09 Stanford Rook Ltd Immunotherapeuitic agent
EP2316466B1 (en) * 2001-12-11 2013-08-21 Institut Pasteur Gram positive bacteria preparations for the treatment of diseases comprising an immune dysregulation
JP2005531289A (ja) * 2002-02-15 2005-10-20 アゲルプ ファーマ ゲーエムベーハー Ｓ．ａｕｒｅｕｓエンテロトキシンＢ由来の免疫調節ペプチド

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105797145A (zh) * 2010-07-26 2016-07-27 Qu生物制药公司 免疫原性抗炎组合物

Also Published As

Publication number Publication date
IL192048A0 (en) 2009-02-11
WO2007072230A3 (en) 2007-11-22
AU2006327761A1 (en) 2007-06-28
CA2632839A1 (en) 2007-06-28
WO2007072230A2 (en) 2007-06-28
KR20080092384A (ko) 2008-10-15
EP1971352A2 (en) 2008-09-24
MX2008008157A (es) 2008-09-24
JP2009520810A (ja) 2009-05-28
CA2531261A1 (en) 2007-06-21
US20090280146A1 (en) 2009-11-12

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Open date: 20090311