CN101381387A - 制备2’-脱氧-2’,2’-二氟-β-胞苷盐酸盐的方法 - Google Patents
制备2’-脱氧-2’,2’-二氟-β-胞苷盐酸盐的方法 Download PDFInfo
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- CN101381387A CN101381387A CNA2007100456688A CN200710045668A CN101381387A CN 101381387 A CN101381387 A CN 101381387A CN A2007100456688 A CNA2007100456688 A CN A2007100456688A CN 200710045668 A CN200710045668 A CN 200710045668A CN 101381387 A CN101381387 A CN 101381387A
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
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- Saccharide Compounds (AREA)
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Abstract
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Claims (15)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2007100456688A CN101381387B (zh) | 2007-09-06 | 2007-09-06 | 制备2'-脱氧-2',2'-二氟-β-胞苷盐酸盐的方法 |
PCT/CN2007/003072 WO2009030075A1 (fr) | 2007-09-06 | 2007-10-29 | Procédé de préparation d'hydrochlorure 2'-désoxy-2',2'-difluoro-β-cytidine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2007100456688A CN101381387B (zh) | 2007-09-06 | 2007-09-06 | 制备2'-脱氧-2',2'-二氟-β-胞苷盐酸盐的方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101381387A true CN101381387A (zh) | 2009-03-11 |
CN101381387B CN101381387B (zh) | 2011-08-31 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN2007100456688A Active CN101381387B (zh) | 2007-09-06 | 2007-09-06 | 制备2'-脱氧-2',2'-二氟-β-胞苷盐酸盐的方法 |
Country Status (2)
Country | Link |
---|---|
CN (1) | CN101381387B (zh) |
WO (1) | WO2009030075A1 (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101606947B (zh) * | 2009-08-06 | 2011-03-30 | 山东罗欣药业股份有限公司 | 一种盐酸吉西他滨组合物及制备方法 |
CN103224541A (zh) * | 2013-04-27 | 2013-07-31 | 江苏豪森药业股份有限公司 | 吉西他滨α-异构体转化回收工艺 |
CN106317147A (zh) * | 2015-07-06 | 2017-01-11 | 扬州硒瑞恩生物医药科技有限公司 | 新的核苷类化合物及其制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006011713A1 (en) * | 2004-07-29 | 2006-02-02 | Hanmi Pharm. Co., Ltd. | 1-α-HALO-2,2-DIFLUORO-2-DEOXY-D-RIBOFURANOSE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF |
WO2006071090A1 (en) * | 2004-12-30 | 2006-07-06 | Hanmi Pharm. Co., Ltd. | Method for the preparation of 2'-deoxy-2',2'-difluorocytidine |
CN101024667B (zh) * | 2007-03-30 | 2011-01-26 | 湖北益泰药业有限公司 | 盐酸吉西他宾的合成方法 |
-
2007
- 2007-09-06 CN CN2007100456688A patent/CN101381387B/zh active Active
- 2007-10-29 WO PCT/CN2007/003072 patent/WO2009030075A1/zh active Application Filing
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101606947B (zh) * | 2009-08-06 | 2011-03-30 | 山东罗欣药业股份有限公司 | 一种盐酸吉西他滨组合物及制备方法 |
CN103224541A (zh) * | 2013-04-27 | 2013-07-31 | 江苏豪森药业股份有限公司 | 吉西他滨α-异构体转化回收工艺 |
CN106317147A (zh) * | 2015-07-06 | 2017-01-11 | 扬州硒瑞恩生物医药科技有限公司 | 新的核苷类化合物及其制备方法 |
CN106317147B (zh) * | 2015-07-06 | 2018-11-27 | 扬州硒瑞恩生物医药科技有限公司 | 核苷类化合物及其制备方法 |
Also Published As
Publication number | Publication date |
---|---|
CN101381387B (zh) | 2011-08-31 |
WO2009030075A1 (fr) | 2009-03-12 |
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Free format text: FORMER OWNER: SHANGHAI DISAINUO CHEMICAL PHARMACEUTICAL CO., LTD. Owner name: SHANGHAI XIDI PHARMACEUTICAL CO., LTD. Free format text: FORMER OWNER: DISAINO MEDICINE DEVELOPMENT CO., LTD, SHANGHAI Effective date: 20110214 |
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Free format text: CORRECT: ADDRESS; FROM: 201203 NO.1479, ZHANGHENG ROAD, ZHANGJIANG HIGH TECHNOLOGY PARK, PUDONG NEWDISTRICT, SHANGHAI TO: 201203 BUILDING 9, NO.1999, ZHANGHENG ROAD, ZHANGJIANG HIGH TECHNOLOGY PARK, PUDONG NEW DISTRICT, SHANGHAI |
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Effective date of registration: 20110214 Address after: 201203, building 1999, No. 9 Zhang Heng Road, Zhangjiang hi tech park, Shanghai, Pudong New Area Applicant after: Shanghai Xidi Pharmaceutical Co., Ltd. Address before: 201203 Zhang Heng road Shanghai, Pudong New Area Zhangjiang hi tech Park No. 1479 Applicant before: Disaino Medicine Development Co., Ltd, Shanghai Co-applicant before: Shanghai Disainuo Chemical Pharmaceutical Co., Ltd. |
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Owner name: SHANGHAI CHUANGNUO PHARMACEUTICAL CO., LTD. Free format text: FORMER NAME: SHANGHAI XIDI PHARMACEUTICAL CO., LTD. |
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CP01 | Change in the name or title of a patent holder |
Address after: 201203, building 1999, No. 9 Zhang Heng Road, Zhangjiang hi tech park, Shanghai, Pudong New Area Patentee after: Shanghai Chuangnuo Pharmaceutical Co., Ltd. Address before: 201203, building 1999, No. 9 Zhang Heng Road, Zhangjiang hi tech park, Shanghai, Pudong New Area Patentee before: Shanghai Xidi Pharmaceutical Co., Ltd. |