CN101360506A - 创伤愈合的方法 - Google Patents

创伤愈合的方法 Download PDF

Info

Publication number
CN101360506A
CN101360506A CNA2006800516339A CN200680051633A CN101360506A CN 101360506 A CN101360506 A CN 101360506A CN A2006800516339 A CNA2006800516339 A CN A2006800516339A CN 200680051633 A CN200680051633 A CN 200680051633A CN 101360506 A CN101360506 A CN 101360506A
Authority
CN
China
Prior art keywords
euphorbia
wound
ingenol
patient
pep005
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2006800516339A
Other languages
English (en)
Chinese (zh)
Inventor
S·M·奥格伯恩
D·托马斯
R·莫斯利
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Peplin Research Pty Ltd
Original Assignee
Peplin Research Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2005906601A external-priority patent/AU2005906601A0/en
Application filed by Peplin Research Pty Ltd filed Critical Peplin Research Pty Ltd
Publication of CN101360506A publication Critical patent/CN101360506A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNA2006800516339A 2005-11-25 2006-11-24 创伤愈合的方法 Pending CN101360506A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2005906601A AU2005906601A0 (en) 2005-11-25 Therapeutic methods and compositions
AU2005906601 2005-11-25

Publications (1)

Publication Number Publication Date
CN101360506A true CN101360506A (zh) 2009-02-04

Family

ID=38066849

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2006800516339A Pending CN101360506A (zh) 2005-11-25 2006-11-24 创伤愈合的方法

Country Status (9)

Country Link
US (2) US20090215884A1 (https=)
EP (1) EP1965818A4 (https=)
JP (1) JP2009517345A (https=)
KR (1) KR20080077625A (https=)
CN (1) CN101360506A (https=)
BR (1) BRPI0618926A2 (https=)
CA (1) CA2629899A1 (https=)
NZ (1) NZ568168A (https=)
WO (1) WO2007059584A1 (https=)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102316866A (zh) * 2009-02-13 2012-01-11 派普林研究股份有限公司 皮肤治疗
CN102844294A (zh) * 2010-04-16 2012-12-26 利奥制药有限公司 结晶巨大戟二萜醇甲基丁烯酸酯
CN103402969A (zh) * 2010-12-22 2013-11-20 利奥实验室有限公司 3-酰基-巨大戟二萜醇ii
CN103402977A (zh) * 2010-12-22 2013-11-20 利奥实验室有限公司 巨大戟二萜醇-3-酰化物iii和巨大戟二萜醇-3-氨基甲酸酯
CN103443066A (zh) * 2010-12-22 2013-12-11 利奥实验室有限公司 巨大戟二萜醇-3-酰化物i
CN104411685A (zh) * 2012-06-26 2015-03-11 利奥实验室有限公司 3-o-杂芳基-巨大戟二萜醇
CN105055448A (zh) * 2015-05-25 2015-11-18 中国人民解放军第三军医大学第一附属医院 铜离子制剂在制备促进皮肤角质形成细胞增殖药物或敷料中的用途
CN106619600A (zh) * 2016-03-28 2017-05-10 中国科学院遗传与发育生物学研究所 巨大戟醇及其衍生物在增强溶酶体生成中的应用
CN115677520A (zh) * 2022-11-18 2023-02-03 扬州大学 一种二萜化合物及其制备方法和应用

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ801700A0 (en) 2000-06-07 2000-06-29 Peplin Research Pty Ltd Enzyme and viral activation
EP1838330A4 (en) 2004-12-13 2010-07-07 Peplin Research Pty Ltd TREATMENT OF SOLID TUMORS
JP5291369B2 (ja) * 2008-03-31 2013-09-18 株式会社ナリス化粧品 ケラチノサイト増殖促進剤
US8273387B2 (en) 2009-08-26 2012-09-25 Mary Kay Inc. Topical skin formulations comprising plant extracts
WO2012005876A2 (en) * 2010-06-30 2012-01-12 Avon Products, Inc. Compositions and methods for stimulating magp-1 to improve the appearance of skin
US9402823B2 (en) 2010-12-17 2016-08-02 Leo Laboratories Limited Ingenols for treating seborrheic keratosis
WO2012176015A1 (en) * 2011-06-24 2012-12-27 Leo Pharma A/S Methods for treating uv-damaged skin and scc tumors and for removing tattoos with topical ingenol mebutate
GB201110777D0 (en) 2011-06-24 2011-08-10 Aqua Bio Technology Asa Methods and uses
EP2790670A1 (en) * 2011-12-12 2014-10-22 Leo Laboratories Limited Gel compositions
US20130251782A1 (en) * 2012-03-22 2013-09-26 Leo Laboratories Limited Topical application of ingenol mebutate with occlusion
KR20150027831A (ko) * 2012-07-06 2015-03-12 레오 파마 에이/에스 피부에 활성 성분을 전달하기 위한 막-형성 중합체를 포함하는 국소 조성물
US9962364B2 (en) 2012-12-26 2018-05-08 A-Z Ltd. Wound healing accelerator
US20150366789A1 (en) * 2013-03-13 2015-12-24 Avon Place, Inc. Glochidium wallichianum extracts and methods of use
KR20180118795A (ko) * 2016-03-18 2018-10-31 인트렉손 코포레이션 Vii형 콜라겐 결핍증의 치료를 위한 조성물 및 방법

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3809749A (en) * 1971-03-05 1974-05-07 Amazon Natural Drug Co Topical pharmaceutical composition and method employing sap from the tree croton lechleri
DE2902506A1 (de) * 1979-01-23 1980-07-24 Deutsches Krebsforsch Verwendung von nicht oder nur gering irritierenden und/oder promovierenden diterpenalkoholen und von derivaten davon als antineoplastische mittel
US4418064A (en) * 1982-09-29 1983-11-29 The United States Of America As Represented By The Secretary Of Agriculture Chemotherapeutically active maytansinoids: treflorine, trenudine, and N-methyltrenudone
US4560774A (en) * 1982-11-17 1985-12-24 Arizona State University Macrocyclic lactones
US5886017A (en) * 1986-06-11 1999-03-23 Procyon Pharmaceuticals, Inc. Protein kinase C modulators. E.
US5145842A (en) * 1986-06-11 1992-09-08 Alder Research Center Limited Partnership Protein kinase c. modulators. d.
US5886019A (en) * 1986-06-11 1999-03-23 Procyon Pharmaceuticals, Inc. Protein kinase C modulators. F.
US5643948A (en) * 1986-06-11 1997-07-01 Procyon Pharmaceuticals, Inc. Protein kinase C modulators. K.
US5891906A (en) * 1986-06-11 1999-04-06 Procyon Pharmaceuticals, Inc. Polyacetate-derived phorboids having anti-inflammatory and other uses
US5891870A (en) * 1986-06-11 1999-04-06 Procyon Pharmaceuticals, Inc. Protein kinase C modulators Q
US5716968A (en) * 1986-06-11 1998-02-10 Procyon Pharmaceuticals, Inc. Protein kinase C modulators. H.
US5962498A (en) * 1986-06-11 1999-10-05 Procyon Pharmaceuticals, Inc. Protein kinase C modulators. C. indolactam structural-types with anti-inflammatory activity
US5750568A (en) * 1986-06-11 1998-05-12 Procyon Pharmaceuticals, Inc. Protein kinase C Modulators. L.
DE4102054A1 (de) * 1991-01-24 1992-07-30 Geb Szenasi Tamas Verwendung der pflanze euphorbia hirta l. und ihrer extrakte sowie ihrer wirkstoffe
US5863938A (en) * 1991-03-01 1999-01-26 Warner Lambert Company Antibacterial-wound healing compositions and methods for preparing and using same
US5317009A (en) * 1991-08-26 1994-05-31 New York University Anti-HIV proteins GAP 31, DAP 30 and DAP 32 and therapeutic uses thereof
US6593371B1 (en) * 1993-05-19 2003-07-15 Jeff J. Staggs Treatment for wart and related disorders
US5874464A (en) * 1995-01-13 1999-02-23 The United States Of America As Represented By The Department Of Health And Human Services Conformationally constrained diacylglycerol analogues
US5932613A (en) * 1996-07-03 1999-08-03 Millennium Pharmaceuticals, Inc. Anticancer agents
AUPO864097A0 (en) 1997-08-19 1997-09-11 Peplin Pty Ltd Anti-cancer compounds
DE59901057D1 (de) * 1999-01-29 2002-05-02 Sid Soc Ind De La Doux S A Zerkleinerungsvorrichtung mit wenigstens einer drehenden Welle
KR20020020808A (ko) * 1999-08-13 2002-03-15 스무크 존 질병의 광역학적 치료를 위한 국부투여 약물 및 그 방법
JP2001139468A (ja) * 1999-11-11 2001-05-22 Lead Chemical Co Ltd 抗ウイルス作用を有するホルボール誘導体
AUPQ801700A0 (en) * 2000-06-07 2000-06-29 Peplin Research Pty Ltd Enzyme and viral activation
AUPQ923100A0 (en) * 2000-08-07 2000-08-31 Peplin Research Pty Ltd Treatment of prostate cancer
US6923993B2 (en) * 2001-12-12 2005-08-02 Nicholas J. Donato Process of isolating extract from the Euphorbia obesa plant and methods for using the same
US7390499B2 (en) * 2002-04-26 2008-06-24 Lohmann & Rauscher Gmbh Microbial cellulose wound dressing for treating chronic wounds
WO2005043155A1 (en) * 2003-10-21 2005-05-12 Cedars-Sinai Medical Center System and method for the treatment of cancer, including cancers of the central nervous system
EP1628673B1 (en) * 2004-01-01 2007-03-07 Panacea Biotec Limited Pharmaceutical compositions comprising an extract of euphorbia prostrata
BRPI0504797B1 (pt) * 2005-10-27 2020-02-04 Pele Nova Biotecnologia S.A. formulação tópica, método de tratamento cosmético para rejuvenescimento da pele, método de tratamento cosmético e uso de uma formulação

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102316866A (zh) * 2009-02-13 2012-01-11 派普林研究股份有限公司 皮肤治疗
CN102844294A (zh) * 2010-04-16 2012-12-26 利奥制药有限公司 结晶巨大戟二萜醇甲基丁烯酸酯
CN103402969A (zh) * 2010-12-22 2013-11-20 利奥实验室有限公司 3-酰基-巨大戟二萜醇ii
CN103402977A (zh) * 2010-12-22 2013-11-20 利奥实验室有限公司 巨大戟二萜醇-3-酰化物iii和巨大戟二萜醇-3-氨基甲酸酯
CN103443066A (zh) * 2010-12-22 2013-12-11 利奥实验室有限公司 巨大戟二萜醇-3-酰化物i
CN103402977B (zh) * 2010-12-22 2016-01-20 利奥实验室有限公司 巨大戟二萜醇-3-酰化物iii和巨大戟二萜醇-3-氨基甲酸酯
CN104411685A (zh) * 2012-06-26 2015-03-11 利奥实验室有限公司 3-o-杂芳基-巨大戟二萜醇
CN104411685B (zh) * 2012-06-26 2017-03-29 利奥实验室有限公司 3‑o‑杂芳基‑巨大戟二萜醇
CN105055448A (zh) * 2015-05-25 2015-11-18 中国人民解放军第三军医大学第一附属医院 铜离子制剂在制备促进皮肤角质形成细胞增殖药物或敷料中的用途
CN106619600A (zh) * 2016-03-28 2017-05-10 中国科学院遗传与发育生物学研究所 巨大戟醇及其衍生物在增强溶酶体生成中的应用
CN115677520A (zh) * 2022-11-18 2023-02-03 扬州大学 一种二萜化合物及其制备方法和应用
CN115677520B (zh) * 2022-11-18 2024-04-02 扬州大学 一种二萜化合物及其制备方法和应用

Also Published As

Publication number Publication date
KR20080077625A (ko) 2008-08-25
BRPI0618926A2 (pt) 2011-09-13
EP1965818A1 (en) 2008-09-10
US20160317486A1 (en) 2016-11-03
EP1965818A4 (en) 2010-02-17
US20090215884A1 (en) 2009-08-27
CA2629899A1 (en) 2007-05-31
NZ568168A (en) 2012-06-29
JP2009517345A (ja) 2009-04-30
WO2007059584A1 (en) 2007-05-31

Similar Documents

Publication Publication Date Title
CN101360506A (zh) 创伤愈合的方法
US10231992B2 (en) Antioxidant composition
JP6239041B2 (ja) 微生物感染の治療に使用するためのタマリンド種子多糖
US20200297780A1 (en) Anti-inflammatory compositions, methods and uses thereof
UA76415C2 (uk) Застосування похідних бігуаніду для отримання лікарського препарату з ефектом загоєння ран
Ayuningtyas et al. Expression of VEGF and CD-31 in traumatic ulcer of diabetic Wistar rats after application of Citrus limon peel essential oil
Getahun et al. In vivo evaluation of 80% methanolic leaves crude extract and solvent fractions of buddleja polystachya fresen (buddlejaceae) for wound healing activity in normal and diabetic mice
Skórkowska-Telichowska et al. Wound coverage by the linen dressing accelerates ulcer healing
Aramwit Bio-response to silk sericin
CN113546031A (zh) 促进角质层更新的组合物及其制备方法与应用
CN117257808B (zh) 吴茱萸次碱在制备促进伤口愈合的产品中的应用
Nganlasom et al. Effects of Centella asiatica linn. and Garcinia mangostana linn. on the healing of dermal wounds in diabetic rats
CN1245220C (zh) 促进皮肤创面快速修复的新型敷料材料
Chandran et al. Syzygium mundagam bark methanol extract restores skin to normal in diabetic wounded rats
CN109364290A (zh) 一种薰衣草精油脂质体液体创可贴及其制备方法
Yensuari et al. Effectiveness Of Red Betel Leaf Ointment (Piper Crocatum, Ruiz & Pav) On Slash Wounds In White Mice
Seran et al. THE EFFECTIVENESS OF MORINGA (Moringa oleifera) ROOT EXTRACT GEL IN HEALING INCISION AND DIABETIC WOUND
US11439655B2 (en) Compounds for use in wound healing and angiogenesis
US20200390841A1 (en) Compositions and methods for treating wounds
CN113304074B (zh) 一种可促进皮肤屏障功能的油脂组合物
Rukyat et al. The effect of Kepok Banana (Musa paradisiaca) Peel Extract on macroscopic and histopathological features of excision wound healing in mice skin
AU2006317523A1 (en) Methods for wound healing
Onah et al. Evaluation of Healing and Microbial Responses to Surgical Wounds in Alloxan-induced Diabetic Rabbits
CN120617284A (zh) 一种具有抗炎和修复皮肤屏障损伤作用的组合物、乳膏及其制备方法与应用
RO138001A0 (ro) Hidrogel multifuncţional pe bază de componente de origine marină şi vegetală pentru tratamentul rănilor cronice şi procedeu de obţinere

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20090204