CN101317903A - Medicine for treating leucoderma and its preparation method - Google Patents
Medicine for treating leucoderma and its preparation method Download PDFInfo
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- CN101317903A CN101317903A CNA2007100557161A CN200710055716A CN101317903A CN 101317903 A CN101317903 A CN 101317903A CN A2007100557161 A CNA2007100557161 A CN A2007100557161A CN 200710055716 A CN200710055716 A CN 200710055716A CN 101317903 A CN101317903 A CN 101317903A
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Abstract
The present invention discloses a drug for remedying the skin disease, in particular to a drug for remedying the vitligo. The present invention also relates to the preparation method for the drug. Caltrop, lithospermum, rosewood, bistort rhizome, safflower, liquorice, swallowwort root, prepared tuber fleece-flower root, rhizome atractylodis, gentian, stephanotis and cuttlebone are smashed into fine powder to be filtered through a sieve to 100 to 120 meshes and mixed uniformly. Peach seed is smashed to be compounded with the powder, the loose powder preparation of the present invention is obtained and then is made into pills; the pill preparation is obtained after the pills are dried. The drug remedies the vitligo with obvious effect and also has good curative effect on the skin diseases such as the psoriasis, the seborrheic dermatitis, etc.
Description
Technical field
The invention discloses a kind of medicine for the treatment of dermatosis, specifically, it is a kind of preparation method for the treatment of leukodermic medicine and this medicine thereof.
Background technology
As everyone knows, dermatosis such as treatment vitiligo, doctor trained in Western medicine does not still have the good curing method, and doctor trained in Western medicine mainly is based on antibiotic antiinflammatory sterilization treatment.But said method can only play mitigation, cure the symptoms, not the disease, though some are arranged to dermatosis Chinese patent medicines such as treatment vitiligo, but because effect is not fairly obvious, the patient still has to rely on some Western medicine, at present, still find dermatosis medicines such as a kind of effective treatment vitiligo and preparation method thereof.
Summary of the invention
The objective of the invention is provides a kind of Chinese medicine preparation that can treat dermatosis such as vitiligo in order to overcome deficiency of the prior art.
Another object of the present invention provide this medicine preparation method.
Solution of the present invention be base motherland medical science to leukodermic understanding of dermatosis and Therapeutic Principle, with reference to the modern pharmacological research achievement, from Chinese medicine, filter out, thereby reach the purpose of treatment treatment dermatosis vitiligo effective medicine.
In order to achieve the above object, technical scheme of the present invention is:
Medicine of the present invention is made (consumption is a weight portion) by following component:
Fructus Tribuli 200-250 part Radix Arnebiae (Radix Lithospermi) 50-100 part Lignum Dalbergiae Odoriferae 50-100 part
Rhizoma Bistortae 50-100 part Radix Cynanchi Atrati 50-100 part Semen Persicae 50-100 part
Flos Carthami 50-100 part Radix Polygoni Multiflori Preparata 50-100 part Radix Glycyrrhizae 50-100 part
Rhizoma Atractylodis 20-50 part Radix Gentianae 20-50 part Radix Stephaniae Cepharanthae 20-50 part
Endoconcha Sepiae 20-50 part
Medicine optimum weight part proportioning of the present invention is:
76 parts of 76 parts of Lignum Dalbergiae Odoriferaes of 227 portions of Radix Arnebiae (Radix Lithospermi)s of Fructus Tribuli
76 parts in 76 parts of Semen Persicaes of 76 portions of Radix Cynanchi Atratis of Rhizoma Bistortae
76 parts in 76 portions of Radix Glycyrrhizaes of 76 parts of Radix Polygoni Multiflori Preparatas of Flos Carthami
76 parts of 30 parts of Radix Stephaniae Cepharanthaes of 30 parts of Radix Gentianae of Rhizoma Atractylodis
30 parts of Endoconcha Sepiaes
The method that above-mentioned each component is made medicine of the present invention is: above 13 flavors, and except that Semen Persicae, 12 flavors such as all the other Lignum Dalbergiae Odoriferaes are ground into fine powder; Peach kernel powder is broken into fine powder and above-mentioned powder is joined, sieves 100---120 orders, mixing promptly gets powder, uses water pill, and drying promptly gets pill.
The dosage form of product of the present invention is pill (watered pill) or powder, and character is that lark is to the tan watered pill; Feeble QI, mildly bitter flavor.Instructions of taking is oral, a 2.5g, 2 times on the one.
Medicine of the present invention has QI and blood regulating, the effect of eliminating blood stasis and removing ecchymoses.Be used for disharmony between QI and blood, the vitiligo due to meridian stasis stagnates is evident in efficacy, and to psoriasis, diseases such as seborrheic dermatitis skin also have better curative effect.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the crude drug selected for use of the present invention, each component meet pharmaceutical control law regulation, reasonable recipe, nontoxic, harmless to human body;
2, medicine of the present invention need not decoct, and is easy to carry taking convenience;
3, short treating period, instant effect, cheap.
4, the medicine source is extensive.
Chinese medicine thinks that leucoderma disease is many because of internal injury caused by excess of seven emotions, depression of liver-QI, and functional activity of QI being not smooth is felt ailment said due to cold or exposure again, and obstruction of meridian forms; Or since the natural endowment deficiency, caused by liver and kidney deficiency, and deficient qi and blood can not nourish due to the skin.Modern medicine thinks that the paathogenic factor of primary disease has heredity, autoimmune, endocrine disturbance etc.
Symptom feature: primary disease is sent out in the youth well, and family history can be arranged.Show as skin and occur the depigmentation speckle suddenly, enlarge gradually, formation is differed in size, white patch in irregular shape.Clear border, smooth surface, the normal skin color of surrounding skin is deepened.The white macula number is indefinite, can isolate existence or merge in blocks.Have to expand to a certain degree the back state of an illness relatively stable, general the whole body that has.Small number of patients Pigmented speckle occurs in the central authorities of white macula.
A kind of medicine for the treatment of dermatosis of the present invention through clinical observation in 5 years, through contrasting and statistical procedures with matched group, proves that it is evident in efficacy to treatment patients with vitiligo 35 examples, now clinical summary is reported as follows:
One, case is selected
Adopt the method for random packet to be divided into treatment group and matched group, the contrast of dividing into groups.Distribute treatment to organize 35 examples MethodsThe cases enrolled by table of random number, matched group 34 examples.
Two, clinical trial method
This test adopts the mode of single blind random packet parallel control to carry out.The experimenter is assigned to treatment group and matched group by the table of random number method, require two groups consistent as much as possible at aspects such as sex, age, the state of an illness, the courses of disease, adopt clinic case but need strict control variable factor.
Treatment group medication: oral medicine of the present invention, a 2.5g, 2 times on the one;
The matched group medication: vitiligo capsule, oral.One time 3～4,2 times on the one.
Three, result of the test
Treatment group medication: oral medicine of the present invention, a 2.5g, 2 times on the one;
The matched group medication: vitiligo capsule, oral.One time 3～4,2 times on the one.
Four, clinical effectiveness
The comparison of table 1 clinical efficacy
The comparison of table 2 tcm syndrome curative effect
Table 3 white macula size and form situation of change relatively
Comparison before and after the unusual patient treatment of table 4 histopathology
From table 7,8,9,10 as seen, medicine of the present invention has curative effect preferably to therapy for vitiligo, compares there was no significant difference (P＞0.05) with matched group.
The present invention is the determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs method according to motherland's Traditional Chinese medical theory " outer sick treatment by oral administration of medicines ", " control outer must first Zhi Qinei, Zhi Qineibizhiqigen ", and with effective component extracting the animals and plants, scientific composition forms from traditional drugs.
Fructus Tribuli in the side, it is antipruritic to invigorate blood circulation, and suppressing the hyperactive liver resolving depression, department of dermatologry are commonly used in comparatively obstinate skin pruritus disease, as vitiligo, psoriasis, chronic urticaria, neurodermatitis, chronic eczema etc.; Radix Arnebiae (Radix Lithospermi), Radix Cynanchi Atrati, Rhizoma Bistortae clearing away heat and cooling blood, the detoxifcation rash increases the skin photosensitization, makes skin pigment calm fast.Be usually used in vitiligo, subacute and chronic eczema, seborrheic dermatitis etc. clinically; Lignum Dalbergiae Odoriferae, Semen Persicae, Flos Carthami promoting flow of QI and blood, logical hundred arteries and veins of transferring promote the fresh blood growth; Rhizoma Atractylodis, Radix Gentianae, Radix Polygoni Multiflori, Endoconcha Sepiae are regulated the QI and blood balance, the convergence granulation promoting; Radix Glycyrrhizae is in harmonious proportion many medicines.All medicines match, QI and blood regulating, and eliminating blood stasis and removing ecchymoses can be treated all kinds of dermatosis chronic diseases.
Claims (4)
1, the leukodermic medicine of a kind of treatment is characterized in that it is the medicament of being made by the following weight proportion raw material:
Fructus Tribuli 200-250 part Radix Arnebiae (Radix Lithospermi) 50-100 part Lignum Dalbergiae Odoriferae 50-100 part
Rhizoma Bistortae 50-100 part Radix Cynanchi Atrati 50-100 part Semen Persicae 50-100 part
Flos Carthami 50-100 part Radix Polygoni Multiflori Preparata 50-100 part Radix Glycyrrhizae 50-100 part
Rhizoma Atractylodis 20-50 part Radix Gentianae 20-50 part Radix Stephaniae Cepharanthae 20-50 part
Endoconcha Sepiae 20-50 part.
2, the leukodermic medicine of treatment according to claim 1 is characterized in that each crude drug weight proportion is:
76 parts of 76 parts of Lignum Dalbergiae Odoriferaes of 227 portions of Radix Arnebiae (Radix Lithospermi)s of Fructus Tribuli
76 parts in 76 parts of Semen Persicaes of 76 portions of Radix Cynanchi Atratis of Rhizoma Bistortae
76 parts in 76 portions of Radix Glycyrrhizaes of 76 parts of Radix Polygoni Multiflori Preparatas of Flos Carthami
76 parts of 30 parts of Radix Stephaniae Cepharanthaes of 30 parts of Radix Gentianae of Rhizoma Atractylodis
30 parts of Endoconcha Sepiaes.
3,, it is characterized in that said medicament is powder or ball according to claim 1, the leukodermic medicine of 2 described treatments.
4, the leukodermic medicine of treatment according to claim 3 preparation method, it is characterized in that: Fructus Tribuli, Radix Arnebiae (Radix Lithospermi), Lignum Dalbergiae Odoriferae, Rhizoma Bistortae, Radix Cynanchi Atrati, Flos Carthami, Radix Glycyrrhizae, Radix Polygoni Multiflori Preparata, Rhizoma Atractylodis, Radix Gentianae, Radix Stephaniae Cepharanthae, Endoconcha Sepiae, be ground into fine powder, be screened to the 100--120 order, mixing is pulverized Semen Persicae and above-mentioned powder is joined, and promptly gets loose powder agent of the present invention, use water pill, be drying to obtain pill.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007100557161A CN101317903A (en) | 2007-06-06 | 2007-06-06 | Medicine for treating leucoderma and its preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007100557161A CN101317903A (en) | 2007-06-06 | 2007-06-06 | Medicine for treating leucoderma and its preparation method |
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| Publication Number | Publication Date |
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| CN101317903A true CN101317903A (en) | 2008-12-10 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007100557161A Pending CN101317903A (en) | 2007-06-06 | 2007-06-06 | Medicine for treating leucoderma and its preparation method |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102697905A (en) * | 2012-05-27 | 2012-10-03 | 李承平 | Medicinal combination capsules for dispelling wind, relieving itching, smoothing liver and dispelling melancholy |
| CN108743691A (en) * | 2018-08-27 | 2018-11-06 | 王浩骅 | A kind of application of pink blood-cleaning pill compound preparation in preparing treatment chloasma, freckle drug |
-
2007
- 2007-06-06 CN CNA2007100557161A patent/CN101317903A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102697905A (en) * | 2012-05-27 | 2012-10-03 | 李承平 | Medicinal combination capsules for dispelling wind, relieving itching, smoothing liver and dispelling melancholy |
| CN108743691A (en) * | 2018-08-27 | 2018-11-06 | 王浩骅 | A kind of application of pink blood-cleaning pill compound preparation in preparing treatment chloasma, freckle drug |
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Open date: 20081210 |