CN101292998A - Use of fly-maggot powder in anti-fatigue, anti-senescence and anti-adiposity health care function aspects - Google Patents

Use of fly-maggot powder in anti-fatigue, anti-senescence and anti-adiposity health care function aspects Download PDF

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Publication number
CN101292998A
CN101292998A CNA2008100619270A CN200810061927A CN101292998A CN 101292998 A CN101292998 A CN 101292998A CN A2008100619270 A CNA2008100619270 A CN A2008100619270A CN 200810061927 A CN200810061927 A CN 200810061927A CN 101292998 A CN101292998 A CN 101292998A
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China
Prior art keywords
maggot powder
fly maggot
fly
fatigue
aging
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CNA2008100619270A
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Chinese (zh)
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沈荣法
傅正伟
胡晓华
许杨
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Individual
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Individual
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Priority to CNA2008100619270A priority Critical patent/CN101292998A/en
Publication of CN101292998A publication Critical patent/CN101292998A/en
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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses an application of a fly maggot powder for the health-care functions of anti-fatigue, anti-aging and anti-obesity. The fly maggot powder is used for producing health care products of anti-fatigue, anti-aging and anti-obesity. Five percent of fly maggot powder is added into the feed for feeding the strain of D-galactose-induced aging C57BL/6 rat to test and find that the fly maggot powder has remarkable effect in anti-fatigue; in a rat model induced by combined biological rhythm disorder and the D-galactose, the fly maggot powder can effectively prevent the reduction of liver weight, the descending of the activity and the corresponding gene expression of superoxide dismutase, glutathione peroxidase, catalase and other antioxidases, and the increase of the content of MDA of the products of lipid peroxidation caused by aging. The fly maggot powder has remarkable efficacy of anti-aging; 5 percent of the fly maggot powder is added in the high-fat feed, which can effectively prevent the rapid growth of Wistar rats as a result of high-fat diet and can suggests that the fly maggot powder has remarkable effect of anti-obesity.

Description

The purposes of a kind of resisting fatigue of fly maggot powder, defying age and obesity health care aspect
Technical field
The invention belongs to the biological health field, relate in particular to a kind of purposes of resisting fatigue, defying age and obesity health care aspect of fly maggot powder.
Background technology
The fertility of fly is occupied the forefront in insecticide, and fly maggot protein matter is high-quality protein, is not only the raw material of high-quality high protein feed, also can extract egg albumen powder, exploitation senior nutrition, space food, medicine etc.In addition, fly larvae also contains a large amount of unsaturated fatty acids, and unsaturated fatty acid has functions such as antioxidation, vessel softening, enhancing blood supply, promotion brain.In sum, fly maggot powder can be used as health product and has important exploitation and be worth.Yet fly maggot powder slowly not can not get development and application as the health care product because there being the support of relevant gross data at present.
Summary of the invention
The purpose of this invention is to provide a kind of fly maggot powder as purposes with health care aspects such as resisting fatigue, defying age and obesity.
Fly maggot powder is used to prepare anti-fatigue health-product containing, antisenescence health product and obesity health product.
With number of patent application is that 200510060277.4 fly maggot breeding method is cultured fly larvae, makes fly maggot powder, and 5% fly maggot powder is made an addition to the feedstuff inductive old and feeble C57BL/6 strain mice of D-galactose of feeding, and finds that fly maggot powder has significant antifatigue effect; In the mouse model of D-galactose and the disorderly combined induction of biorhythm, fly maggot powder can effectively prevent to alleviate because of the old and feeble liver weight that causes, can effectively stop because of superoxide dismutase in the old and feeble serum that causes, glutathion peroxidase, activities of antioxidant enzymes and the decline of corresponding gene expression and the risings of lipid peroxidation product MDA content such as catalase, beta-galactosidase gene is expressed descend and kidney in the proteic Klotho gene expression of coding deferring senility rise, the embodiment fly maggot powder has significant senile-resistant efficacy; Add in high lipid food that 5% fly maggot powder can prevent effectively because the rising of T-CHOL in the quick growth of the Wistar rat body weight that high fat diet causes and the blood, the prompting fly maggot powder has can significant obesity and the effect of certain cholesterol reducing.
The specific embodiment
Number of patent application is that the step of 200510060277.4 fly maggot breeding method is as follows:
1) chrysomyia megacephala (big head golden fly) is raised
Adopt transparent mode fly room, roof, draw in the room and be provided with many rope supplies and have a rest, chrysomyia megacephala (big head golden fly) is a food with animal proteinum, brown sugar, fruit, with Herba Epimedii, lysine, vitamin as urging the ovum element, collect fly blow with collection ovum plate, on collection ovum dish, put ten thousand/ carbonic acid ammonia preparation Testa Tritici, lay eggs to lure kind of fly to concentrate.
2) fly larvae is raised
Adopt airy fly larvae room, the roof transparent material, ventilation fan and fan are housed in the room, window, seal with screen window is tight in the place that ventilation fan and room are interlinked to the outside, place a plurality of maggot culturing pools in the fly larvae room, in maggot culturing pool, put into fly-maggot feed, put into above-mentioned fly blow simultaneously, the maggot culturing pool temperature is controlled at 28 ℃~60 ℃, educate the fly pond by light-burning magnesium powder 30%~50%, oxidase 30%~50%, wood slag 15%~25% raw material is made, the percentage by weight component of fly-maggot feed is a Rana nigromaculata 15%~30%, fresh-water fishes 15%~30%, Cordyceps 0.1%~0.2%, Ganoderma powder 1%~2%, chicken 20%~30%, fruit 25%~35%, all the other are the other plant feedstuff, pulverize the back and ferment in the after fermentation pond 4~6 days.
Embodiment 1-resisting fatigue
With number of patent application is that 200510060277.4 fly maggot breeding method is cultured fly larvae, makes fly maggot powder, adds 5% fly maggot powder in feedstuff, in proportion protein and the fat constituent in the replacing base feedstuff.With C57BL/6 strain mice is experimental subject, after raising for 5 weeks, every mice is put into high 29cm, diameter 30cm separately, in the bucket of depth of water 25cm, the mice behavior is by online infrared monitor control instrument (Activity MonitoringSystem, Muromachi, Tokyo, Japan) monitoring in real time, collect the per minute data, totally 6 minutes, swimming test check mouse muscle motor capacity and anti-fatigue ability.The quantity of motion of not adding the matched group of fly maggot powder has on average descended 50.86% in swimming after 6 minutes, and the interpolation group of fly maggot powder has only descended 39.87%.Found that adding 5% fly maggot powder in the feedstuff can improve the anti-fatigue ability that the D-galactose causes aging mice significantly.
Embodiment 2-defying age and antioxidation
With number of patent application is that 200510060277.4 fly maggot breeding method is cultured fly larvae, makes fly maggot powder, adds 5% fly maggot powder in feedstuff, in proportion protein and the fat constituent in the replacing base feedstuff.C57BL/6 strain mice with D-galactose and the disorderly combined induction of biorhythm is an experimental subject, raises the back execution of 6 weeks.D-galactose and biorhythm be disorderly, and to make that the mouse liver weight average has descended in 6 weeks of combined induction about 6.61%, and the feedstuff that 5% fly maggot powder of feeding adds can effectively prevent to alleviate because of the old and feeble liver weight that causes; Physiochemical indice shows, compare with the normal control group, the disorderly combined induction of D-galactose and biorhythm makes superoxide dismutase in the serum, glutathion peroxidase and catalase activities of antioxidant enzymes distinguish to have descended 10.34%, 30.96% and 44.38%, and make the lipid peroxidation product MDA content rise 49.88%, and fly maggot powder can stop the decline of these activities of antioxidant enzymes in the serum and the rising of MDA content completely effectively; By detecting the expression of mice SAG, find that fly maggot powder can effectively stop average 21.98~24.43% the expression in liver of above-mentioned three kinds of antioxidase genes to descend, beta-galactosidase gene is expressed recover in normal and the kidney the proteic Klotho gene expression of coding deferring senility rise 27.72%, the embodiment fly maggot powder has significant antioxidation and senile-resistant efficacy.
Embodiment 3-obesity
With number of patent application is that 200510060277.4 fly maggot breeding method is cultured fly larvae, make fly maggot powder, adding 5% fly maggot powder in high-sugar-fat-diet (adding 10% Adeps Sus domestica and 20% sucrose in normal feedstuff), is experimental subject with the Wistar rat, raises for 6 weeks.Do the body weight record weekly one time.The body weight of the normal group that obesity group of during the 6th week the body weight and the high lipid food of fly maggot powder raising group being fed and normal diet are fed compares.After 6 weeks, the weight average of the normal group that normal diet is fed is 247.8 grams, obesity group weight increase to 264.6 gram that high-sugar-fat-diet is fed, and fly maggot powder feed the group rat body weight be 246.8 the gram, be starkly lower than fat group rat, and and the body weight of normal rats do not have difference, prove that fly maggot powder has the effect of preventing the obesity that caused by high fat diet significantly.

Claims (3)

1. a fly maggot powder is characterized in that as the purposes of health care aspect fly maggot powder is used to prepare anti-fatigue health-product containing.
2. a fly maggot powder is characterized in that as the purposes of health care aspect fly maggot powder is used to prepare antisenescence health product.
3. a fly maggot powder is characterized in that as the purposes of health care aspect fly maggot powder is used to prepare the obesity health product.
CNA2008100619270A 2008-05-27 2008-05-27 Use of fly-maggot powder in anti-fatigue, anti-senescence and anti-adiposity health care function aspects Pending CN101292998A (en)

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CNA2008100619270A CN101292998A (en) 2008-05-27 2008-05-27 Use of fly-maggot powder in anti-fatigue, anti-senescence and anti-adiposity health care function aspects

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CNA2008100619270A CN101292998A (en) 2008-05-27 2008-05-27 Use of fly-maggot powder in anti-fatigue, anti-senescence and anti-adiposity health care function aspects

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102533809A (en) * 2012-02-23 2012-07-04 山西省农业科学院生物技术研究中心 Jujube glutathione peroxidase gene
CN104082728A (en) * 2014-06-10 2014-10-08 芜湖市好亦快食品有限公司三山分公司 Edible fly larva and honey freeze-dried powder and preparation method thereof
CN105693840A (en) * 2016-03-28 2016-06-22 张晟 Preparation method of fly larva polypeptides

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102533809A (en) * 2012-02-23 2012-07-04 山西省农业科学院生物技术研究中心 Jujube glutathione peroxidase gene
CN104082728A (en) * 2014-06-10 2014-10-08 芜湖市好亦快食品有限公司三山分公司 Edible fly larva and honey freeze-dried powder and preparation method thereof
CN104082728B (en) * 2014-06-10 2016-02-10 芜湖市好亦快食品有限公司三山分公司 A kind of edible fly larva honey freeze-dried powder and preparation method thereof
CN105693840A (en) * 2016-03-28 2016-06-22 张晟 Preparation method of fly larva polypeptides

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Open date: 20081029