CN101283688A - Pure Chinese medicine anti-avian influenza air disinfectant and its preparation method - Google Patents
Pure Chinese medicine anti-avian influenza air disinfectant and its preparation method Download PDFInfo
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- CN101283688A CN101283688A CNA2007100394446A CN200710039444A CN101283688A CN 101283688 A CN101283688 A CN 101283688A CN A2007100394446 A CNA2007100394446 A CN A2007100394446A CN 200710039444 A CN200710039444 A CN 200710039444A CN 101283688 A CN101283688 A CN 101283688A
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Abstract
The invention relates to a Chinese medicinal preparation used as air disinfectant, more particularly to a herbal air disinfectant for controlling avian influenza and a preparation method thereof. The herbal air disinfectant for controlling avian influenza is prepared from the following materials in weight ratio: 1-10 parts of Hypericum perforatum, 1-10 parts of Scutellaria baicalensis, 1-10 parts of Isatis indigotica root, 1-10 parts of Lonicera japonica flower, 1-10 parts of Pogostemon cablin and 1-10 parts of Eupatorium fortunei. The air disinfectant is produced by the following steps: mixing the above herbal materials, decocting in water for 1-3 times (boiling for 2-3 hours for each time), collecting volatile oils and decoctions, mixing the decoctions, standing overnight, collecting supernatant, filtering, concentrating, precipitating with ethanol, removing ethanol, diluting with water, stirring, standing, collecting supernatant, filtering, adding the volatile oils, adjusting the concentration of drug liquid to 4-10% of the raw materials, stirring and packaging. According to the technical proposal mentioned above, the air disinfectant has no irritation and toxicity, can efficiently kill various pathogenic microorganisms, particularly avian influenza virus, and is used for the prevention and treatment of avian influenza.
Description
Technical field
The present invention relates to the Chinese medicine air sanitizer, particularly Chinese medicine air sanitizer of a kind of anti-avian influenza and preparation method thereof.
Background technology
Bird flu is the abbreviation of Bird Flu, is the bird communicable disease that is caused by influenza A virus.That avian influenza virus can be divided into is highly pathogenic, low pathogenicity and non-pathogenic three major types.Wherein highly pathogenic bird flu is the disease that is caused by H5 and the inferior strain of H7 (is representative with H5N1 and H7N7).Highly Pathogenic Avian Influenza Virus (HPAIV) can the direct infection mankind.1997, the area, Hong Kong in China, the highly pathogenic bird flu virus H 5 N 1 type has caused 18 people to infect, and 6 people's death confirm that first highly pathogenic bird flu can jeopardize people's life.Till in November, 2005, find that the popular area of H5N1 virus has: states such as Cambodia, inland of China, Taiwan, Hong Kong, Indonesia, Japan, Laos, Malaysia, Korea S, Thailand, Vietnam, Mongolia, Russia, Kazakhstan, Turkey, Romania, Greece.Avian influenza virus can enter human body by digestive tract and respiratory tract and infect to the people, and human directly contact is subjected to the poultry and the ight soil thereof of avian flu virus infection or directly contacts avian influenza virus also can be infected.By the spittle and contact respiratory secretions also is the route of transmission.Air is the important channel that bird flu is propagated.
Air disinfection method at present commonly used is a chemicals, as physical methods such as chemical method such as Peracetic acid, lactic acid, hydrogen peroxide, formaldehyde, 84 thimerosals, glutaraldehyde and ultraviolet irradiation, ozone generators.These methods can be killed pathogenic microorganisms, and effect is quick, and valid density is low, obtains effect preferably.But certain defective is respectively arranged, poor as toxic, excitant, metal protection, lasting effect; Manyly itself constitute pollutant again, influence health to some extent, uncomfortable tenant in common's environment; All personnel must leave the theatre during sterilization, and operating system will have safeguard procedures; Sterilization back peculiar smell can not very fast elimination, and long-term use meeting has the danger of accumulate poisoning etc. to human body.
Chinese medicine not only can be treated human body diseases, many Chinese medicines are external stronger antibiosis and antiviral functions again, and air sterillization is also had use value widely, is particularly having under people's condition, can reach safe and effective air sterillization, therefore more and more be subject to people's attention.
Summary of the invention
One of purpose of the present invention is to solve the above-mentioned defective of existing air sanitizer, a kind of pure Chinese medicine anti-avian influenza air disinfectant is provided, but this pure Chinese medicine anti-avian influenza air disinfectant is fresh air both, can suppress or kill pathogenic microbes such as body surface, article and airborne bacterium, virus again, resist the microorganism that causes bird flu, SARS.
Another object of the present invention is to provide the preparation method of above-mentioned pure Chinese medicine anti-avian influenza air disinfectant.
Realize that the object of the invention technical scheme is: a kind of pure Chinese medicine anti-avian influenza air disinfectant, its component and weight ratio are:
1～10 part of hypericum perforatum,
1～10 part of the root of large-flowered skullcap,
1～10 part of isatis root,
1～10 part of honeysuckle,
1～10 part of wrinkled giant hyssop,
1～10 part of eupatorium.
Above-mentioned pure Chinese medicine anti-avian influenza air disinfectant, its component and weight ratio can for:
2 parts of hypericum perforatums,
2 parts of the roots of large-flowered skullcap,
2 parts of isatis roots,
2 parts of honeysuckles,
1 part of wrinkled giant hyssop,
1 part of eupatorium.
Above-mentioned pure Chinese medicine anti-avian influenza air disinfectant, its component and weight ratio can also for:
2 parts of hypericum perforatums,
2 parts of the roots of large-flowered skullcap,
1 part of isatis root,
1 part of honeysuckle,
1 part of wrinkled giant hyssop,
1 part of eupatorium.
The preparation method of the pure Chinese medicine anti-avian influenza air disinfectant of above-mentioned various Different Weight ratios is: each described medicinal material among the claim 1-3 is mixed, mixing back medicinal material water decocts 1-3 time, the water that at every turn adds the doubly former dose volume of water 6-10, boiled 2-3 hour at every turn, and all collected volatile oil and decocting liquid at every turn; Collecting decoction filters, and leaves standstill 24 hours, draws supernatant, filters, and it is 1.15～1.2 concentrate that filtrate is concentrated into relative concentration; After the concentrate cooling, add the ethanol of 2.5～3.5 times of amount of liquid, stir evenly, left standstill 36 hours, make precipitation, filter decompression filtrate recycling ethanol; Add the water dilution of 8～12 times of former dose volumes, stir evenly, left standstill 24 hours, get supernatant, filter, add the volatile oil of being collected, and soup transferred to contain crude drug 4-10%, stir evenly packing.
Since adopted above-mentioned technical solution, the pure Chinese medicine anti-avian influenza air disinfectant of the present invention nonirritant, and no toxicity integrates sterilization and fresh air, is adapted at various occasions and uses.Can effectively kill various pathogenic microorganisms, can effectively resist the invasion and attack of avian influenza virus especially, various diseases such as control bird flu.
Embodiment
A kind of pure Chinese medicine anti-avian influenza air disinfectant, it is made up of hypericum perforatum, the root of large-flowered skullcap, isatis root, honeysuckle, wrinkled giant hyssop, eupatorium etc., and prescription and preparation technology are as follows:
Prescription (forming and weight ratio):
1～10 part of hypericum perforatum,
1～10 part of the root of large-flowered skullcap,
1～10 part of isatis root,
1～10 part of honeysuckle,
1～10 part of wrinkled giant hyssop,
1～10 part of eupatorium
Preparation technology:
Above medicinal material is mixed, use water boiling and extraction 1-3 time, collect volatile oil and decocting liquid.Merge extract, leave standstill, concentrate.Alcohol precipitation reclaims ethanol.Thin up adds volatile oil, and soup transferred to contains medicinal material 4-10%, and is canned.
The present invention is based on theory of traditional Chinese medical science, the infectious disease that the air-borne transmission pathogenic microorganisms causes belongs to the traditional Chinese medical science " warm disease " category, can be divided into damp and hot and warm two big classes by its cause of disease character.Chinese medicine antiseptic is a rule with the clearing damp heat-clearing mainly, thus based on remove dampness by means of aromatics, clearing heat and detoxicating two class Chinese medicines.
Wrinkled giant hyssop, the Eupatorium class Chinese medicine of removing dampness by means of aromatics has fragrance to ward off the effect of turbid dampness elimination, can remove 4 o'clock foul gas, to control cards such as damp-warm syndrome.The hot temperature fragrance of wrinkled giant hyssop is delivered relieving summer-heat, and dampness elimination is turbid, wards off dirty evil.Eupatorium gas is fragrant as blue, the heresy of driving away summer heat, wards off oxious gas.Their main active ingredient is volatile oil, existing broad-spectrum antibacterial action and inside and outside antivirus action, can remove again smell, flavouring, fresh air.
Honeysuckle, hypericum perforatum, Radix Isatidis, Scutellaria antipyretic and antidotal type Chinese medicine, this type of medicine is longer than clearing heat and detoxicating, and modern study proof majority has antibacterial and bacteriostasis and antivirus action.
The hypericin that extracts from Chinese herbal medicine hypericum perforatum (St John ' s Wort) can be killed avian influenza virus, as the choice drug of viral diseases such as treatment and birds flu-preventing.Country's bird flu reference laboratory is checked " hypericin ", and the result proves that this Chinese medicine preparation reaches 100% and 99.99% respectively to the killing rate of bird flu H5NI and H9N2 subtype virus.
More than the prescription of Zu Chenging can be kept away dirty dehumidifying, clearing summer heat, inhibition bacterium and virus, effectively resists the invasion and attack of avian influenza virus.
The fungistatic effect of product of the present invention is as follows:
1. through three repeated tests, stoste effect 5 minutes is to colibacillary logarithm value 〉=5.00 of on average killing.
2. through three repeated tests, stoste effect 5 minutes is on average killed logarithm value 〉=5.00 to staphylococcus aureus.
3. after directly wooden table surface evenly being sprayed, embrocate sterilization, act on 5 minutes, wooden table surface natural bacteria on average killed logarithm value 〉=1.00.
4. through the air sterillization field trial, spray this thimerosal stoste 400ml with atomizer, effect 60min is to 30M
3The average extinction rate of work room air natural bacteria is 92%.
This product uses in certain bird flu epidemic-stricken area, and is respond well.Through scientific experiment and clinic trial, this product has the following advantages:
1. can effectively kill various pathogenic microorganisms, various diseases such as control bird flu.
2. can integrate sterilization and fresh air.
3. pure natural components, nonirritant, nontoxic negative reaction is adapted at various occasions and uses.
Below by embodiments of the invention, the invention will be further described:
Embodiment 1:
Batching:, following Chinese medicine medicinal material is mixed according to weight ratio:
2 parts of hypericum perforatums, 10g
2 parts of the roots of large-flowered skullcap, 10g
2 parts of isatis roots, 10g
2 parts of honeysuckles, 10g
1 part of wrinkled giant hyssop, 5g
1 part of eupatorium, 5g
Preparation technology is:
To add the water of 10 times of volumes that mix medicinal material according to the Chinese medicine medicinal material of above weight ratio mixing, boil 3 hours, collect volatile oil and decocting liquid.The dregs of a decoction add the water of 6 times of former dose volumes again, boil 2 hours, collect volatile oil and decocting liquid.Collecting decoction filters, and leaves standstill 24 hours, draws supernatant, filters.It is 1.15～1.2 that filtrate is concentrated into relative concentration, puts coldly, adds the ethanol of 2.5～3.5 times of amount of liquid, stirs evenly, and leaves standstill 36 hours, makes precipitation, filters.Decompression filtrate recycling ethanol, the water of 8～12 times of former dose volumes of adding stirs evenly, and leaves standstill 24 hours.Get supernatant, filter, add water adjustment soup and contain crude drug 4%, stir evenly packing.
Embodiment 2:
Batching:, following Chinese medicine medicinal material is mixed according to weight ratio:
2 parts of hypericum perforatums, 10g
2 parts of the roots of large-flowered skullcap, 10g
1 part of isatis root, 5g
1 part of honeysuckle, 5g
1 part of wrinkled giant hyssop, 5g
1 part of eupatorium, 5g
Preparation technology is:
To add the water of 10 times of volumes that mix medicinal material according to the Chinese medicine medicinal material of above weight ratio mixing, boil 3 hours, collect volatile oil and decocting liquid.The dregs of a decoction add the water of 6 times of former dose volumes again, boil 2 hours, collect volatile oil and decocting liquid.Collecting decoction filters, and leaves standstill 24 hours, draws supernatant, filters.It is 1.15～1.2 that filtrate is concentrated into relative concentration, puts coldly, adds the ethanol of 2.5～3.5 times of amount of liquid, stirs evenly, and leaves standstill 36 hours, makes precipitation, filters.Decompression filtrate recycling ethanol, the water of 8～12 times of former dose volumes of adding stirs evenly, and leaves standstill 24 hours.Get supernatant, filter, add water adjustment soup and contain crude drug 10%, stir evenly packing.
Embodiment 3:
Batching:, following Chinese medicine medicinal material is mixed according to weight ratio:
2 parts of hypericum perforatums,
2 parts of the roots of large-flowered skullcap,
1 part of isatis root,
1 part of honeysuckle,
1 part of wrinkled giant hyssop,
1 part of eupatorium.
Preparation technology is:
To add the water of 10 times of volumes that mix medicinal material according to the Chinese medicine medicinal material of above weight ratio mixing, boil 3 hours, collect volatile oil and decocting liquid.The dregs of a decoction add the water of 6 times of former dose volumes again, boil 2 hours, collect volatile oil and decocting liquid.The dregs of a decoction add the water of 4 times of former dose volumes again, boil 2 hours, collect volatile oil and decocting liquid.Collecting decoction filters, and leaves standstill 24 hours, draws supernatant, filters.It is 1.15～1.2 that filtrate is concentrated into relative concentration, puts coldly, adds the ethanol of 2.5～3.5 times of amount of liquid, stirs evenly, and leaves standstill 36 hours, makes precipitation, filters.Decompression filtrate recycling ethanol, the water of 8～12 times of former dose volumes of adding stirs evenly, and leaves standstill 24 hours.Get supernatant, filter, add water adjustment soup and contain crude drug 5%, stir evenly, packing is canned.
Above embodiment is only for the usefulness that the present invention is described, but not limitation of the present invention, person skilled in the relevant technique, under the situation that does not break away from the spirit and scope of the present invention, can also make various conversion or modification, therefore all technical schemes that are equal to also should belong to category of the present invention, should be limited by each claim.
Claims (4)
1, a kind of pure Chinese medicine anti-avian influenza air disinfectant is characterized in that its component and weight ratio are:
1～10 part of hypericum perforatum,
1～10 part of the root of large-flowered skullcap,
1～10 part of isatis root,
1～10 part of honeysuckle,
1～10 part of wrinkled giant hyssop,
1～10 part of eupatorium.
2, pure Chinese medicine anti-avian influenza air disinfectant according to claim 1 is characterized in that its component and weight ratio are:
2 parts of hypericum perforatums,
2 parts of the roots of large-flowered skullcap,
2 parts of isatis roots,
2 parts of honeysuckles,
1 part of wrinkled giant hyssop,
1 part of eupatorium.
3, pure Chinese medicine anti-avian influenza air disinfectant according to claim 1 is characterized in that its component and weight ratio are:
2 parts of hypericum perforatums,
2 parts of the roots of large-flowered skullcap,
1 part of isatis root,
1 part of honeysuckle,
1 part of wrinkled giant hyssop,
1 part of eupatorium.
4, a kind of preparation method as each described pure Chinese medicine anti-avian influenza air disinfectant among the claim 1-3, it is characterized in that, each described medicinal material among the claim 1-3 is mixed, mixing back medicinal material water decocts 1-3 time, the water that at every turn adds the doubly former dose volume of water 6-10, boiled 2-3 hour at every turn, and all collected volatile oil and decocting liquid at every turn; Collecting decoction filters, and leaves standstill 24 hours, draws supernatant, filters, and it is 1.15～1.2 concentrate that filtrate is concentrated into relative concentration; After the concentrate cooling, add the ethanol of 2.5～3.5 times of amount of liquid, stir evenly, left standstill 36 hours, make precipitation, filter decompression filtrate recycling ethanol; Add the water dilution of 8～12 times of former dose volumes, stir evenly, left standstill 24 hours, get supernatant, filter, add the volatile oil of being collected, and soup transferred to contain crude drug 4-10%, stir evenly packing.
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| CN2007100394446A CN101283688B (en) | 2007-04-12 | 2007-04-12 | Pure Chinese medicine anti-avian influenza air disinfectant and its preparation method |
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| CN101283688B CN101283688B (en) | 2011-10-26 |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102133336A (en) * | 2010-01-21 | 2011-07-27 | 常州善美药物研究开发中心有限公司 | Traditional Chinese medicine composite, and preparation method and application thereof |
| CN102715197A (en) * | 2012-06-21 | 2012-10-10 | 袁静 | Aerosol disinfectant |
| CN104381324A (en) * | 2014-11-26 | 2015-03-04 | 成都顺发消洗科技有限公司 | Disinfectant |
| CN105211121A (en) * | 2015-10-27 | 2016-01-06 | 成都顺发消洗科技有限公司 | A kind of preparation method of plant type air sanitizer |
| CN105532751A (en) * | 2016-01-15 | 2016-05-04 | 王芳 | Disinfectant for laboratory department |
| CN106390166A (en) * | 2016-09-17 | 2017-02-15 | 佛山市顺德区宝铜金属科技有限公司 | Air freshener with sterilizing effect and preparation method thereof |
| CN106963905A (en) * | 2017-03-30 | 2017-07-21 | 蒋世芬 | A kind of medicine of avian typhoid |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1653909A (en) * | 2004-02-10 | 2005-08-17 | 高平 | Chinese medicinal incense for disinfecting and sterilizing air to prevent livestock bird flu from cross contaminating to human being |
| CN1781522A (en) * | 2004-11-30 | 2006-06-07 | 王丙尧 | Chinese medicine composition for treating avian flu |
| CN100337651C (en) * | 2005-03-15 | 2007-09-19 | 华南农业大学 | Chinese medicine composition for preventing bird flu |
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2007
- 2007-04-12 CN CN2007100394446A patent/CN101283688B/en active Active
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102133336A (en) * | 2010-01-21 | 2011-07-27 | 常州善美药物研究开发中心有限公司 | Traditional Chinese medicine composite, and preparation method and application thereof |
| CN102133336B (en) * | 2010-01-21 | 2014-06-11 | 常州善美药物研究开发中心有限公司 | Traditional Chinese medicine composite, and preparation method and application thereof |
| CN102715197A (en) * | 2012-06-21 | 2012-10-10 | 袁静 | Aerosol disinfectant |
| CN104381324A (en) * | 2014-11-26 | 2015-03-04 | 成都顺发消洗科技有限公司 | Disinfectant |
| CN105211121A (en) * | 2015-10-27 | 2016-01-06 | 成都顺发消洗科技有限公司 | A kind of preparation method of plant type air sanitizer |
| CN105532751A (en) * | 2016-01-15 | 2016-05-04 | 王芳 | Disinfectant for laboratory department |
| CN106390166A (en) * | 2016-09-17 | 2017-02-15 | 佛山市顺德区宝铜金属科技有限公司 | Air freshener with sterilizing effect and preparation method thereof |
| CN106963905A (en) * | 2017-03-30 | 2017-07-21 | 蒋世芬 | A kind of medicine of avian typhoid |
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| Publication number | Publication date |
|---|---|
| CN101283688B (en) | 2011-10-26 |
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