CN101279025A - Chinese medicine preparation for curing melancholia - Google Patents

Chinese medicine preparation for curing melancholia Download PDF

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Publication number
CN101279025A
CN101279025A CNA2008101037224A CN200810103722A CN101279025A CN 101279025 A CN101279025 A CN 101279025A CN A2008101037224 A CNA2008101037224 A CN A2008101037224A CN 200810103722 A CN200810103722 A CN 200810103722A CN 101279025 A CN101279025 A CN 101279025A
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China
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chinese medicine
medicine preparation
parts
traditional chinese
radix
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CNA2008101037224A
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王信锁
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BEIJING WANSHOUTONG PHARMACEUTICAL TECHNOLOGY CORP
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BEIJING WANSHOUTONG PHARMACEUTICAL TECHNOLOGY CORP
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Priority to CNA2008101037224A priority Critical patent/CN101279025A/en
Publication of CN101279025A publication Critical patent/CN101279025A/en
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Abstract

The invention relates to a traditional Chinese medicine preparation for curing depression, which adopts more than 10 Chinese traditional herbs as raw materials, such as pinellia ternate, hawthorn, peony peel rhizoma cyperi, etc. The traditional Chinese medicine preparation of the invention has the functions of dispersing the depressed liver-energy, regulating the flow of qi, relieving depression and calming the nerves. The traditional Chinese medicine preparation of the invention is developed by combining the latest modern scientific achievements on the basis of dialectic treatment of traditional Chinese medicine science. The traditional Chinese medicine preparation aims at providing the traditional Chinese medicine preparation for curing depression. The traditional Chinese medicine preparation of the invention is characterized by exact effectiveness, safety and convenience, no toxicity or side effects and low price.

Description

A kind of Chinese medicine preparation for the treatment of strongly fragrant disease
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of strongly fragrant disease, is that a kind of to treat strongly fragrant disease be the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Strongly fragrant cause of disease feelings will is not relaxed, depression and stagnation of QI and causing a disease.With the kind melancholy of depression, irritable emotion, or kind the crying of irritability is primary symptom.Be more common in neurosis, hysteria.The generation of strongly fragrant disease, because of disgruntled, ponder over, the institute of grieved worried seven emotions hinders, and causes the liver failing to maintain the normal flow of QI, spleen loses fortuneization, the mind is not normal, the internal organs yin and yang qi and blood disorder forms.The stagnation of QI, wet resistance, expectorant stagnate though its pathological factor has, food stagnation, fire are contained, blood stasis is multiple, always are earlier with the stagnation of QI.Prolonged illness then can damage the mind, or causes heart spleen deficiency of both QI and blood, or causes hyperactivity of fire caused by deficiency of YIN.Dialectically should distinguish deficiency and excess and cacosplanchnia position.General gas, blood, fire stagnation are main relevant with liver, food, wet, expectorant is mainly relevant with spleen; Deficiency syndrome are then the closest with heart relation, secondly are that losing of liver,spleen,kidney is empty.Treatment based on the mediation mechanism of qi, especially fall ill from the beginning of, the mediation mechanism of qi to preventing the great significance of the state of an illness.In addition, should be according to the pathogenic factor of double folder, cooperate respectively and invigorate blood circulation, reduce phlegm, damp eliminating, pathogenic fire reducing, help digestion.Deficiency syndrome are then answered tranquilizing by nourishing the heart, vigorate qi and replenish the blood, nourishing the liver and kidney.The traditional Chinese medical science is divided syndrome of stagnation of liver qi, syndrome of qi depression transforming into fire, the melancholy disease type Coryza Treated by Syndrome Differentiation such as card, syndrome of deficiency of both heart and spleen of overtaxing one's nerves clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of strongly fragrant disease.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by following raw materials by weight proportions:
0.1~2 part of 1.0~4 parts of Cortex Magnoliae Officinalis of 1.0~4 parts of Radix Salviae Miltiorrhizaes of Pericarpium Citri Reticulatae
0.1~2 part of 0.1~2 part of Cortex Moutan of 1.0~4 parts of Radix Bupleuri of Radix Paeoniae Rubra
0.1~2 part of 0.1~2 part of Fructus Crataegi of 1.0~4 portions of Rhizoma Cyperis of Fructus Aurantii
0.1~2 part of 0.1~2 part of Rhizoma Pinelliae Preparatum of 1.0~4 portions of Fructus Gardeniaes of Radix Angelicae Sinensis.
The weight proportion of each crude drug of optimization formula of the present invention is:
0.5~1.5 part of 1.5~2.5 parts of Cortex Magnoliae Officinalis of 1.5~2.5 parts of Radix Salviae Miltiorrhizaes of Pericarpium Citri Reticulatae
0.5~1.5 part of 0.5~1.5 part of Cortex Moutan of 1.5~2.5 parts of Radix Bupleuri of Radix Paeoniae Rubra
0.5~1.5 part of 0.5~1.5 part of Fructus Crataegi of 1.5~2.5 portions of Rhizoma Cyperis of Fructus Aurantii
0.5~1.5 part of 0.5~1.5 part of Rhizoma Pinelliae Preparatum of 1.5~2.5 portions of Fructus Gardeniaes of Radix Angelicae Sinensis.
The weight proportion of each crude drug of optimum formula of the present invention is:
1 part of 2 parts of Cortex Magnoliae Officinalis of 2 parts of Radix Salviae Miltiorrhizaes of Pericarpium Citri Reticulatae
1 part of 1 part of Cortex Moutan of 2 parts of Radix Bupleuri of Radix Paeoniae Rubra
1 part of 1 part of Fructus Crataegi of 2 portions of Rhizoma Cyperis of Fructus Aurantii
1 part of 1 part of Rhizoma Pinelliae Preparatum of 2 portions of Fructus Gardeniaes of Radix Angelicae Sinensis.
Drug action mechanism among the present invention is as follows:
Pericarpium Citri Reticulatae property of medicine suffering, hardship, temperature.Return spleen, stomach, lung meridian.Having in the accent of regulating the flow of vital energy stopping nausea and vomiting by lowering the adverse flow of QI, the effect of drying dampness to eliminate phlegm.It is full vexed to treat chest and diaphragm, abdominal distention, anorexia, vomiting, hiccup; Cough with copious phlegm.Acute mastitis from the beginning of etc.(the 1668th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Paeoniae Rubra property of medicine hardship is slightly cold.Return liver, spleen channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, the carbuncle skin infection, amenorrhea, dysmenorrhea, the metrorrhagia and leukorrhagia stranguria with turbid discharge, the stasis of blood hypochondriac pain that stagnates, the hernia abdominal mass is gathered, injury from falling down etc.(the 1440th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Aurantii property of medicine hardship, acid are slightly cold.Return lung, spleen, stomach, large intestine channel.Has the chest stuffiness relieving of regulating the flow of vital energy, the effect of the stagnant removing food stagnancy of row.Can treat the septum pectorale feeling of fullness, distending pain over the hypochondrium, accumulation of food in the stomach and intes tine due to indigestion, distension and fullness in the abdomen, heavy behind the dysentery, proctoptosis, uterine prolapse etc.(the 2227th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea , mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Salviae Miltiorrhizae property of medicine hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Have blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the effect of removing heat from blood eliminating carbuncle.Can treat menoxenia, dysmenorrhea, amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swells and ache, traumatic injury, heat is gone into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.(the 647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Bupleuri nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Effect with reconciling superficies and interior, soothing the liver, yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).
Rhizoma Cyperi property of medicine suffering, sweet, little hardship, flat.Return liver, tri-jiao channel.Has the resolving depression of regulating the flow of vital energy, regulating menstruation, antiabortive effect.Can treat distending pain over the hypochondrium, distending pain of the breast, hernia pain, menoxenia, gastral cavity abdomen feeling of fullness pain, belch acid regurgitation, vomiting and nausea, abdominal pain during menstruation, bleeding not during menses, frequent fetal movement etc.(the 2341st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Gardeniae property of medicine hardship, cold.GUIXIN, liver, lung, stomach, tri-jiao channel.Has the pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, the effect of removing pathogenic heat from blood and toxic substance from the body.It is vexed to treat calentura, the liver-fire conjunctival congestion, and headache, jaundice due to damp-heat, stranguria is spitted blood, epistaxis, dysentery, hematuria, aphtha of the mouth and tongue, sore swollen toxin is sprained and is swollen and ache etc.(the 2242nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Magnoliae Officinalis property of medicine hardship, suffering, temperature.Return stomach, large intestine channel.Has the circulation of qi promoting intestinal stasis relieving, dampness, the effect of lowering the adverse QI to relieve asthma.Can treat stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, the gastral cavity painful abdominal mass is vomited and diarrhoea, and expectorant is stopped up QI rising in reverse order, and fullness in the chest is breathed with cough etc.(the 2284th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Moutan property of medicine hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Can treat the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatic arthralgia etc.(the 1578th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The acid of the Fructus Crataegi property of medicine, sweet tepor.Return spleen, stomach, Liver Channel.Has promoting digestion and invigorating the stomach, the effect of circulation of qi promoting dissipating blood stasis.Can treat eating accumulation, abdominal distention, dysentery, dysmenorrhea due to blood stasis, amenorrhea, puerperal abdonimal pain, lochiorrhea, hernia or painful and swollen testis, hyperlipemia etc.(the 226th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Pinelliae Preparatum property of medicine suffering, temperature, poisonous.Return spleen, stomach, lung meridian.Has drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the effect of dissolving lump and resolving mass.Can treat the cough with asthma abundant expectoration, vomiting regurgitation, feeling of oppression and fullness in the chest and epigastrium, pain is dizzy, uneasy sleeping at night, goiter sucutaneous nodule, swollen ulcer drug etc.(the 1073rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Bupleuri, Rhizoma Cyperi magnolia obovata; With Pericarpium Citri Reticulatae, Radix Paeoniae Rubra, Fructus Aurantii, Rhizoma Pinelliae Preparatum, Radix Angelicae Sinensis and Radix Salviae Miltiorrhizae is ministerial drug; With Fructus Gardeniae, Cortex Moutan and Fructus Crataegi is adjuvant.All medicines are harmonious, and are total to the tool liver-smoothing, qi-regulating, the effect of resolving stagnation for tranquilization.Treat strongly fragrant disease and have determined curative effect, have no side effect, taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function of the Chinese medicine of respectively distinguishing the flavor of to treat strongly fragrant disease, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat strongly fragrant disease, and the prevention of strongly fragrant disease is also had good effect, treats strongly fragrant disease and has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing medicine of the present invention, as follows through clinical test results to treating the therapeutic effect of strongly fragrant disease; Treat strongly fragrant disease patient 40 examples.Take embodiment 1 decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.31 examples of fully recovering account for 77.5%, and 7 examples that take a turn for the better account for 17.5%, and more 2 examples do not account for 5%, and total effective rate reaches 95%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
Embodiment 1 decoction is pressed following weight weighting raw materials:
1 part of 2 parts of Cortex Magnoliae Officinalis of 2 parts of Radix Salviae Miltiorrhizaes of Pericarpium Citri Reticulatae
1 part of 1 part of Cortex Moutan of 2 parts of Radix Bupleuri of Radix Paeoniae Rubra
1 part of 1 part of Fructus Crataegi of 2 portions of Rhizoma Cyperis of Fructus Aurantii
1 part of 1 part of Rhizoma Pinelliae Preparatum of 2 portions of Fructus Gardeniaes of Radix Angelicae Sinensis.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the strongly fragrant disease of treatment that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.
Embodiment 2 capsules are pressed following weight weighting raw materials:
1 part of 2 parts of Cortex Magnoliae Officinalis of 2 parts of Radix Salviae Miltiorrhizaes of Pericarpium Citri Reticulatae
1 part of 1 part of Cortex Moutan of 2 parts of Radix Bupleuri of Radix Paeoniae Rubra
1 part of 1 part of Fructus Crataegi of 2 portions of Rhizoma Cyperis of Fructus Aurantii
1 part of 1 part of Rhizoma Pinelliae Preparatum of 2 portions of Fructus Gardeniaes of Radix Angelicae Sinensis.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, decoct with water twice, 1.5~2 hours for the first time, 0.5~1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree~85 when spending, the clear paste of relative density 1.08~1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when 50 degree~55 are spent, be concentrated into the clear paste of relative density 1.30~1.32, drying, be ground into fine powder, incapsulate.Adorn 0.3 gram for every, usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2~10, two 2 to three times on the one, three months is a course of treatment.

Claims (3)

1, a kind of Chinese medicine preparation for the treatment of strongly fragrant disease is characterized in that it is made by following raw materials by weight proportions:
0.1~2 part of 1.0~4 parts of Cortex Magnoliae Officinalis of 1.0~4 parts of Radix Salviae Miltiorrhizaes of Pericarpium Citri Reticulatae
0.1~2 part of 0.1~2 part of Cortex Moutan of 1.0~4 parts of Radix Bupleuri of Radix Paeoniae Rubra
0.1~2 part of 0.1~2 part of Fructus Crataegi of 1.0~4 portions of Rhizoma Cyperis of Fructus Aurantii
0.1~2 part of 0.1~2 part of Rhizoma Pinelliae Preparatum of 1.0~4 portions of Fructus Gardeniaes of Radix Angelicae Sinensis.
2, a kind of Chinese medicine preparation for the treatment of strongly fragrant disease according to claim 1, wherein the weight proportion of each crude drug is:
0.5~1.5 part of 1.5~2.5 parts of Cortex Magnoliae Officinalis of 1.5~2.5 parts of Radix Salviae Miltiorrhizaes of Pericarpium Citri Reticulatae
0.5~1.5 part of 0.5~1.5 part of Cortex Moutan of 1.5~2.5 parts of Radix Bupleuri of Radix Paeoniae Rubra
0.5~1.5 part of 0.5~1.5 part of Fructus Crataegi of 1.5~2.5 portions of Rhizoma Cyperis of Fructus Aurantii
0.5~1.5 part of 0.5~1.5 part of Rhizoma Pinelliae Preparatum of 1.5~2.5 portions of Fructus Gardeniaes of Radix Angelicae Sinensis.
3, a kind of Chinese medicine preparation for the treatment of strongly fragrant disease according to claim 1, wherein the weight proportion of each crude drug is:
1 part of 2 parts of Cortex Magnoliae Officinalis of 2 parts of Radix Salviae Miltiorrhizaes of Pericarpium Citri Reticulatae
1 part of 1 part of Cortex Moutan of 2 parts of Radix Bupleuri of Radix Paeoniae Rubra
1 part of 1 part of Fructus Crataegi of 2 portions of Rhizoma Cyperis of Fructus Aurantii
1 part of 1 part of Rhizoma Pinelliae Preparatum of 2 portions of Fructus Gardeniaes of Radix Angelicae Sinensis.
CNA2008101037224A 2008-04-10 2008-04-10 Chinese medicine preparation for curing melancholia Pending CN101279025A (en)

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CNA2008101037224A CN101279025A (en) 2008-04-10 2008-04-10 Chinese medicine preparation for curing melancholia

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Application Number Priority Date Filing Date Title
CNA2008101037224A CN101279025A (en) 2008-04-10 2008-04-10 Chinese medicine preparation for curing melancholia

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CN101279025A true CN101279025A (en) 2008-10-08

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CNA2008101037224A Pending CN101279025A (en) 2008-04-10 2008-04-10 Chinese medicine preparation for curing melancholia

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105494804A (en) * 2015-12-30 2016-04-20 河南千方药业有限公司 Liver dispersing and stasis removing tea and preparation technology thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105494804A (en) * 2015-12-30 2016-04-20 河南千方药业有限公司 Liver dispersing and stasis removing tea and preparation technology thereof

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Open date: 20081008