CN101264162A - Proprietary Chinese medicine for treating wind-cold common cold and preparation technique - Google Patents
Proprietary Chinese medicine for treating wind-cold common cold and preparation technique Download PDFInfo
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- CN101264162A CN101264162A CN 200810103753 CN200810103753A CN101264162A CN 101264162 A CN101264162 A CN 101264162A CN 200810103753 CN200810103753 CN 200810103753 CN 200810103753 A CN200810103753 A CN 200810103753A CN 101264162 A CN101264162 A CN 101264162A
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Abstract
The invention discloses a Chinese patent medicine treating common cold of wind-cold type and the preparation process, which comprises granule, powder, capsule, tablet and medical pill types and is produced by eleven following Chinese herbal medicine material through mixing according to proportion: ephedra, honeysuckle, baikal skullcap root, bupleurum, wild chrysanthemum flower, honeysuckle stem, Chinese rhubarb, prepared rhizome of rehmannia, liquorice root, gardenia and tangerine peel. The Chinese patent medicine has the advantages of dispelling wind and relieving exterior syndrome, clearing heat and toxin, treating cold and obviously improving symptoms such as fever, aversion to coldness, watery nasal discharge, headache, swelling and pain in throat.
Description
Technical field
The invention belongs to the Chinese medicine preparation technical field, relate to a kind of Chinese patent medicine, be specifically related to a kind of Chinese patent medicine and preparation technology thereof who is used for the treatment of anemofrigid cold.
Technical background
Flu is a kind of modal respiratory system disease.Common cold medically is called " cold ", is a kind of respiratory tract commonly encountered diseases that is caused by multiple virus.Wherein 30%～50%, cause by the rhinovirus of certain serotype.Though common cold is mainly in early winter, in any season, as can taking place in spring, summer, the Causative virus of the flu of Various Seasonal is not just the same yet.It is sporadic that the flu case distributes, do not cause popular, the normal bacterial infection that easily merges.The common cold onset is more anxious, and early symptom has pharyngeal dried itching or burning sensation, sneeze, nasal obstruction, watery nasal discharge, begins to be clear water sample nasal mucus, retrogradation after 2～3 days; Can be with pharyngalgia; General do not have heating and General Symptoms, or low grade fever, headache are only arranged.Generally through recovery from illness in 5～7 days.
Flu also is a kind of acute infection rhinitis, causes by Respirovirus, and be main Causative virus wherein with coronavirus and rhinovirus.Virus is discharged from respiratory secretions and is propagated, when Abwehrkraft des Koepers descends, as suffer from cold, malnutrition, overtired, cigarette spills excessively, the chronic disease of systemic disease and nose itself influences respiratory smooth etc., brings out infection easily.Flu outbreak back secondary bacterial infection.Intranasal has dry sensation and gargalesthesia, sneeze, general malaise or low grade fever is arranged during the flu onset, nasal obstruction, hyposmia, a large amount of clear water nasal mucus of stream, nasal mucosa hyperemia, edema is gradually arranged later on, a large amount of clear water samples or purulent secretion etc. are arranged.If no complication, the course of disease is about 7～10 days.
Flu may cause bacterial infection, heals with medicine but necessarily can not at will make.After the human immune system killed virus, the overwhelming majority infected recovery from illness automatically.Blindly Drug therapy can strengthen resistance, thus the infringement human immune system.Do not have medicine can directly kill cold virus in the world, effective ways rely on the human immune system exactly.So flu should be based on supporting treatment, it is light to pay special attention to rest, great quantity of water drinking, diet.This can give immune system muscle power support fully.
The medicine that is used for the treatment of flu has many kinds.Because Chinese patent medicine has little, the eutherapeutic characteristics of side effect, so favored by people.But clinical practice proves, and is improper if Chinese patent medicine is selected for use, but also delay treatment.The traditional Chinese medical science is divided into four types of wind-chill cold, common cold due to wind heat, summer-wet type common cold and influenzas (influenza) with flu.According to the principle of determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, dissimilar flu should be selected different Chinese patent drugs for treatment for use.The symptom of its wind-chill cold is that aversion to cold is heavy, and heating gently or is not generated heat, headache, nasal obstruction, snivel, itching of the throat, cough.At this moment should select the pungent and warm medicine for relieving the exterior syndrome of dispersing wind-cold for use, as Notopterygii Bolus of Nine Ingredients, ginseng and Perillae Decoction, tongxuan lifei pills, can not select for use SUNJU GANMAO PIAN, YINQIAO JIEDU PIAN, antelope to stick up detoxifying pills, tablet of antelope horn for common cold, misuse can increase the weight of the state of an illness or protracted course of disease.
Summary of the invention
The object of the invention is to provide a kind of Chinese patent medicine and preparation technology thereof who is used for the treatment of anemofrigid cold, can satisfy the treatment needs better.
Be achieved through the following technical solutions order of the present invention:
1, the present invention is the Chinese patent medicine of being made by the following weight parts proportion raw material:
Herba Ephedrae 60～150 weight portion Flos Loniceraes 80～200 weight portion Radix Scutellariaes 80～200 weight portions
Radix Bupleuri 60～150 weight portion Flos Chrysanthemi Indicis 80～200 weight portion Caulis Loniceraes 80～200 weight portions
Radix Et Rhizoma Rhei 50～100 weight portion Radix Rehmanniae Preparata 50～100 weight portion Radix Glycyrrhizaes 60～150 weight portions
Fructus Gardeniae 80～200 weight portion Pericarpium Citri Reticulataes 80～200 weight portions
2, best each the parts by weight of raw materials proportioning of prescription of the present invention is:
Herba Ephedrae 120 weight portion Flos Loniceraes 160 weight portion Radix Scutellariaes 160 weight portions
Radix Bupleuri 120 weight portion Flos Chrysanthemi Indicis 160 weight portion Caulis Loniceraes 160 weight portions
Radix Et Rhizoma Rhei 80 weight portion Radix Rehmanniae Preparata 80 weight portion Radix Glycyrrhizaes 120 weight portions
Fructus Gardeniae 160 weight portion Pericarpium Citri Reticulataes 160 weight portions
3, preparation method:
(1) Flos Lonicerae, Radix Bupleuri in the side of getting add the water distillation, collect volatile oil, and aqueous solution and medicinal residues after the distillation are standby;
(2) side's of getting epheday intermedia, Radix Scutellariae, Radix Et Rhizoma Rhei, Radix Glycyrrhizae are ground into coarse powder, and be mixed, with 60～85% ethanol of 6～10 times of medical material amounts, heating and refluxing extraction 3～5 times, each 1 hour.Collect ethanol extract, gradation filters, and behind the decompression filtrate recycling ethanol, adds the water of equivalent, cold preservation 12 hours.Get supernatant, 60 ℃ of water-baths are condensed into the thick paste that relative density is 1.38-1.45, and cold drying is ground into fine powder, and is standby;
(3) aqueous solution and the medicinal residues after the distillation in the taking technique (1) with Flos Chrysanthemi Indici, Caulis Lonicerae, Radix Rehmanniae Preparata, Fructus Gardeniae, Pericarpium Citri Reticulatae, mixed in the side, add an amount of water again, decoct three times, decoct 1 hour at every turn, merge decocting liquid, filter.Filtrate water-bath solvent flashing is to an amount of, adds ethanol and makes and contain the alcohol amount and reach 60% (V/V), and liquid was left standstill in cold preservation.Get supernatant, reclaim under reduced pressure is to nothing alcohol flavor, and water-bath is concentrated into the thick paste that relative density is 1.31-1.38 (80 ℃), and cold drying is ground into fine powder, and is standby;
(4) with above-mentioned fine powder mixing, add an amount of medicine correctives or/and drug excipient sprays into volatile oil, making can be for the oral formulations of clinical practice.
The Chinese patent medicine that the present invention makes is by Herba Ephedrae, Flos Lonicerae, Radix Scutellariae, Radix Bupleuri, Flos Chrysanthemi Indici, Caulis Lonicerae, Radix Et Rhizoma Rhei, Radix Rehmanniae Preparata, Radix Glycyrrhizae, Fructus Gardeniae, the Pericarpium Citri Reticulatae totally ten Chinese crude drug granule that forms of assembly, powder, capsule, tablet, pills etc. in proportion simply, has the function of dispelling wind to relieve the exterior syndrome, heat-clearing and toxic substances removing.Medicine of the present invention has therapeutical effect preferably to flu, can obviously improve symptoms such as heating, aversion to cold, watery nasal discharge, headache, laryngopharynx swelling and pain.
The specific embodiment of form is described in further detail foregoing of the present invention by the following examples.Following example is based on the above-mentioned subject area of the present invention, but is not limited to following example.
The specific embodiment
Embodiment 1: a kind of pill that is used for the treatment of anemofrigid cold
Adopt following prescription:
Herba Ephedrae 120g Flos Lonicerae 160g Radix Scutellariae 160g
Radix Bupleuri 120g Flos Chrysanthemi Indici 160g Caulis Lonicerae 160g
Radix Et Rhizoma Rhei 80g Radix Rehmanniae Preparata 80g Radix Glycyrrhizae 120g
Fructus Gardeniae 160g Pericarpium Citri Reticulatae 160g
Preparation technology:
(1) Flos Lonicerae 160g, Radix Bupleuri 120g in the side of getting add the water distillation, collect volatile oil, and aqueous solution and medicinal residues after the distillation are standby;
(2) side's of getting epheday intermedia 120g, Radix Scutellariae 160g, Radix Et Rhizoma Rhei 80g, Radix Glycyrrhizae 120g are ground into coarse powder, and be mixed, with 75% ethanol of 8 times of medical material amounts, heating and refluxing extraction 4 times, each 1 hour.Collect ethanol extract, gradation filters, and behind the decompression filtrate recycling ethanol, adds the water of equivalent, cold preservation 12 hours.Get supernatant, 60 ℃ of water-baths are condensed into the thick paste that relative density is 1.38-1.45, and cold drying is ground into fine powder, and is standby;
(3) aqueous solution and the medicinal residues after the distillation in the taking technique (1), mixed with Flos Chrysanthemi Indici 160g, Caulis Lonicerae 160g, Radix Rehmanniae Preparata 80g, Fructus Gardeniae 160g, Pericarpium Citri Reticulatae 160g in the side, add an amount of water again, decoct three times, decocted 1 hour at every turn, merge decocting liquid, filter.Filtrate water-bath solvent flashing is to an amount of, adds ethanol and makes and contain the alcohol amount and reach 60% (V/V), and liquid was left standstill in cold preservation.Get supernatant, reclaim under reduced pressure is to nothing alcohol flavor, and water-bath is concentrated into the thick paste that relative density is 1.31-1.38 (80 ℃), and cold drying is ground into fine powder, and is standby;
(4) with above-mentioned fine powder mixing, spray into volatile oil, honey 90～110g made big honeyed pills 1000 balls, promptly during every 100g powder added.
Embodiment 2: a kind of capsule that is used for the treatment of anemofrigid cold
Adopt following prescription:
Herba Ephedrae 60g Flos Lonicerae 80g Radix Scutellariae 80g
Radix Bupleuri 60g Flos Chrysanthemi Indici 80g Caulis Lonicerae 80g
Radix Et Rhizoma Rhei 50g Radix Rehmanniae Preparata 50g Radix Glycyrrhizae 60g
Fructus Gardeniae 80g Pericarpium Citri Reticulatae 80g
Preparation technology:
(1) Flos Lonicerae 80g, Radix Bupleuri 60g in the side of getting add the water distillation, collect volatile oil, and aqueous solution and medicinal residues after the distillation are standby;
(2) side's of getting epheday intermedia 60g, Radix Scutellariae 80g, Radix Et Rhizoma Rhei 50g, Radix Glycyrrhizae 60g are ground into coarse powder, and be mixed, with 70% ethanol of 6 times of medical material amounts, heating and refluxing extraction 3 times, each 1 hour.Collect ethanol extract, gradation filters, and behind the decompression filtrate recycling ethanol, adds the water of equivalent, cold preservation 12 hours.Get supernatant, 60 ℃ of water-baths are condensed into the thick paste that relative density is 1.38-1.45, and cold drying is ground into fine powder, and is standby;
(3) aqueous solution and the medicinal residues after the distillation in the taking technique (1), mixed with Flos Chrysanthemi Indici 80g, Caulis Lonicerae 80g, Radix Rehmanniae Preparata 50g, Fructus Gardeniae 80g, Pericarpium Citri Reticulatae 80g in the side, add an amount of water again, decoct three times, decocted 1 hour at every turn, merge decocting liquid, filter.Filtrate water-bath solvent flashing is to an amount of, adds ethanol and makes and contain the alcohol amount and reach 60% (V/V), and liquid was left standstill in cold preservation.Get supernatant, reclaim under reduced pressure is to nothing alcohol flavor, and water-bath is concentrated into the thick paste that relative density is 1.31-1.38 (80 ℃), and cold drying is ground into fine powder, and is standby;
(4) with above-mentioned fine powder mixing, spray into volatile oil, mixing, airtight 2 hours, encapsulated, make capsule.
Embodiment 3: a kind of granule that is used for the treatment of anemofrigid cold
Adopt following prescription:
Herba Ephedrae 150g Flos Lonicerae 200g Radix Scutellariae 200g
Radix Bupleuri 150g Flos Chrysanthemi Indici 200g Caulis Lonicerae 200g
Radix Et Rhizoma Rhei 100g Radix Rehmanniae Preparata 100g Radix Glycyrrhizae 150g
Fructus Gardeniae 200g Pericarpium Citri Reticulatae 200g
Preparation technology:
(1) Flos Lonicerae 200g, Radix Bupleuri 150g in the side of getting add the water distillation, collect volatile oil, and aqueous solution and medicinal residues after the distillation are standby;
(2) side's of getting epheday intermedia 150g, Radix Scutellariae 200g, Radix Et Rhizoma Rhei 100g, Radix Glycyrrhizae 150g are ground into coarse powder, and be mixed, with 80% ethanol of 10 times of medical material amounts, heating and refluxing extraction 5 times, each 1 hour.Collect ethanol extract, gradation filters, and behind the decompression filtrate recycling ethanol, adds the water of equivalent, cold preservation 12 hours.Get supernatant, 60 ℃ of water-baths are condensed into the thick paste that relative density is 1.38-1.45, and cold drying is ground into fine powder, and is standby;
(3) aqueous solution and the medicinal residues after the distillation in the taking technique (1), mixed with Flos Chrysanthemi Indici 200g, Caulis Lonicerae 200g, Radix Rehmanniae Preparata 100g, Fructus Gardeniae 200g, Pericarpium Citri Reticulatae 200g in the side, add an amount of water again, decoct three times, decocted 1 hour at every turn, merge decocting liquid, filter.Filtrate water-bath solvent flashing is to an amount of, adds ethanol and makes and contain the alcohol amount and reach 60% (V/V), and liquid was left standstill in cold preservation.Get supernatant, reclaim under reduced pressure is to nothing alcohol flavor, and water-bath is concentrated into the thick paste that relative density is 1.31-1.38 (80 ℃), and cold drying is ground into fine powder, and is standby;
(4) with above-mentioned fine powder mixing, with 80% the alcohol granulation that contains 0.5% steviosin, drying sprays into volatile oil after cooling, abundant mixing, and the granulate that sieves makes granule.
Claims (5)
1, a kind of Chinese patent medicine that is used for the treatment of anemofrigid cold is characterized in that what it was made by following parts by weight of Chinese traditional medicine:
Herba Ephedrae 60～150 weight portion Flos Loniceraes 80～200 weight portion Radix Scutellariaes 80～200 weight portions
Radix Bupleuri 60～150 weight portion Flos Chrysanthemi Indicis 80～200 weight portion Caulis Loniceraes 80～200 weight portions
Radix Et Rhizoma Rhei 50～100 weight portion Radix Rehmanniae Preparata 50～100 weight portion Radix Glycyrrhizaes 60～150 weight portions
Fructus Gardeniae 80～200 weight portion Pericarpium Citri Reticulataes 80～200 weight portions
2, a kind of Chinese patent medicine that is used for the treatment of anemofrigid cold as claimed in claim 1 is characterized in that the weight portion proportioning of each Chinese medicine is:
Herba Ephedrae 120 weight portion Flos Loniceraes 160 weight portion Radix Scutellariaes 160 weight portions
Radix Bupleuri 120 weight portion Flos Chrysanthemi Indicis 160 weight portion Caulis Loniceraes 160 weight portions
Radix Et Rhizoma Rhei 80 weight portion Radix Rehmanniae Preparata 80 weight portion Radix Glycyrrhizaes 120 weight portions
Fructus Gardeniae 160 weight portion Pericarpium Citri Reticulataes 160 weight portions
3, as the described a kind of Chinese patent medicine that is used for the treatment of anemofrigid cold of claim 1-2, it is characterized in that the preparation technology of this Chinese patent medicine is:
(1) Flos Lonicerae, Radix Bupleuri in the side of getting add the water distillation, collect volatile oil, and aqueous solution and medicinal residues after the distillation are standby;
(2) side's of getting epheday intermedia, Radix Scutellariae, Radix Et Rhizoma Rhei, Radix Glycyrrhizae are ground into coarse powder, and be mixed, with 60～85% ethanol of 6～10 times of medical material amounts, heating and refluxing extraction 3～5 times, each 1 hour.Collect ethanol extract, gradation filters, and behind the decompression filtrate recycling ethanol, adds the water of equivalent, cold preservation 12 hours.Get supernatant, 60 ℃ of water-baths are condensed into the thick paste that relative density is 1.38-1.45, and cold drying is ground into fine powder, and is standby;
(3) aqueous solution and the medicinal residues after the distillation in the taking technique (1), mixed with Flos Chrysanthemi Indici, Caulis Lonicerae, Radix Rehmanniae Preparata, Fructus Gardeniae, Pericarpium Citri Reticulatae in the side, add an amount of water again, decoct three times, decocted 1 hour at every turn, merge decocting liquid, filter.Filtrate water-bath solvent flashing is to an amount of, adds ethanol and makes and contain the alcohol amount and reach 60% (V/V), and liquid was left standstill in cold preservation.Get supernatant, reclaim under reduced pressure is to nothing alcohol flavor, and water-bath is concentrated into the thick paste that relative density is 1.31-1.38 (80 ℃), and cold drying is ground into fine powder, and is standby;
(4) with above-mentioned fine powder mixing, add an amount of medicine correctives or/and drug excipient sprays into volatile oil, making can be for the oral formulations of clinical practice.
4, a kind of Chinese patent medicine that is used for the treatment of anemofrigid cold as claimed in claim 3 is characterized in that, the medicine correctives that is used for said preparation comprises: the spice of steviosin, sucrose, simple syrup, syrupus citri and synthetic etc.; Drug excipient comprises: dextrin, starch, starch-dextrin mixture, magnesium stearate, Pulvis Talci and the low-substituted hydroxypropyl cellulose etc. under different proportion.
5, a kind of Chinese patent medicine that is used for the treatment of anemofrigid cold as claimed in claim 3 is characterized in that this oral formulations comprises granule, powder, capsule, tablet, pill, but is not limited thereto.
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| Application Number | Priority Date | Filing Date | Title |
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| CN 200810103753 CN101264162A (en) | 2008-04-10 | 2008-04-10 | Proprietary Chinese medicine for treating wind-cold common cold and preparation technique |
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| CN 200810103753 CN101264162A (en) | 2008-04-10 | 2008-04-10 | Proprietary Chinese medicine for treating wind-cold common cold and preparation technique |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102258620A (en) * | 2011-07-21 | 2011-11-30 | 赵志敏 | Chinese medicinal injection for treating mixed infection of swine streptococcus and swine fever and preparation method thereof |
| CN104056093A (en) * | 2014-06-18 | 2014-09-24 | 合肥瑾翔医药科技有限公司 | Traditional Chinese medicinal composition for treating upper respiratory infection |
| CN108354995A (en) * | 2018-05-28 | 2018-08-03 | 陈雨薇 | A kind of flu decoction and preparation method thereof |
-
2008
- 2008-04-10 CN CN 200810103753 patent/CN101264162A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102258620A (en) * | 2011-07-21 | 2011-11-30 | 赵志敏 | Chinese medicinal injection for treating mixed infection of swine streptococcus and swine fever and preparation method thereof |
| CN102258620B (en) * | 2011-07-21 | 2013-01-23 | 赵志敏 | Chinese medicinal injection for treating mixed infection of swine streptococcus and swine fever and preparation method thereof |
| CN104056093A (en) * | 2014-06-18 | 2014-09-24 | 合肥瑾翔医药科技有限公司 | Traditional Chinese medicinal composition for treating upper respiratory infection |
| CN108354995A (en) * | 2018-05-28 | 2018-08-03 | 陈雨薇 | A kind of flu decoction and preparation method thereof |
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Open date: 20080917 |