CN108354995A - A kind of flu decoction and preparation method thereof - Google Patents

A kind of flu decoction and preparation method thereof Download PDF

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CN108354995A
CN108354995A CN201810520233.2A CN201810520233A CN108354995A CN 108354995 A CN108354995 A CN 108354995A CN 201810520233 A CN201810520233 A CN 201810520233A CN 108354995 A CN108354995 A CN 108354995A
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flu
decoction
preparation
safflower
medicinal powder
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陈雨薇
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Abstract

The invention discloses a kind of flu decoctions and preparation method thereof, and the invention belongs to field of medicaments, including following raw material:Mother chrysanthemum, safflower, cow-bezoar, sweet wormwood, bitter ground courage, honeysuckle, dried orange peel, Radix Glycyrrhizae and radix bupleuri; the invention also discloses preparation methods; this method prepares the operation of this six step including drying process, effective component extracting, medicinal powder making, pulverization process, sterilization treatment and decoction; the present invention in existing, for especially influenza therapeutic of catching a cold, ineffective, the longer technical problem of healing time is improved Western medicine; the decoction has the characteristics that good effect, repeatability are less; and this decoction preparation method is simple; medicinal material is easy to get, the stronger feature of universality.

Description

A kind of flu decoction and preparation method thereof
Technical field
The present invention relates to field of medicaments more particularly to a kind of flu decoction and preparation method thereof.
Background technology
Flu, is a kind of slight upper respiratory tract (nose and throat) viral infection.It includes common cold and popularity Flu, influenza is generally more serious than common cold, and additional symptom includes fever, ague and DOMS, systemic Symptom is more apparent.Common cold is also known as acute nasopharyngitis, referred to as catches a cold, is commonly called as " catching cold ", is acute upper respiratory viral infection In most common disease, be in self limiting, but incidence is high more, influence that crowd is wide, amount is big, economic loss is quite huge, and can cause Multiple complications.1~3 day incubation period of flu is differed, and different with virus, enterovirus is most short, adenovirus and respiratory syncystial disease Poison is longer.First there are nose and throat's burning heat sensation mostly, nasal obstruction, sneezing, runny nose, general malaise and DOMS then occurs.Disease Shape reaches peak (virus uncoating) in 48h, and acute nasopharyngitis does not generate heat usually or only low-heat, especially rhinovirus or coronavirus When infection.There can be conjunctival congestion, shed tears, photophobia, eyelid swelled, throat mucosa edema.Whether throat and tracheitis occur because People and Yin virus due to it is different.Virus other than purulent sputum or serious lower respiratory tract symptom prompt rhinovirus merges or secondary bacterial Infection.Its symptom is usually more more serious than being grown up when children's cold, often there is lower respiratory tract symptom and symptom of digestive tract (vomiting, abdomen It rushes down).Flu is more belonging to self limiting, such as without complication, the course of disease 4~10 days.The drug of existing treatment flu is mostly with Western medicine Based on, but Western medicine is often taken Endophytic bacteria can be made to generate certain drug resistance, for those constitutions, poor crowd is outstanding It is children population, and often therapeutic effect is bad for Western medicine, and the time that illness may continue is longer.
And treasure of the Chinese medicine as the Chinese nation, it is made that tremendous contribution for multiplying and being prosperous for the Chinese nation.Tradition The treatment concept of medicine is just gradually received by the world, and traditional medicine is more and more paid close attention to by international community, world wide The interior demand to traditional Chinese medicine is growing, this provides wide space for the development of traditional Chinese medicine.Folks of china traditional Chinese medicine is inclined The example that side, odd-numbered prescription successfully cure difficult and complicated cases is too numerous to enumerate.And Chinese medicine is for Western medicine substantially without any secondary work With not interfering with health, while human body other required elements can also be supplemented.Although Chinese patent (CN102716311A) Daily 1 dose of traditional Chinese herbal decoction for curing mainly anemopyretic cold is disclosed, but decoction treatment flu specific aim is not strong, therapeutic effect is unknown It is aobvious.
The present invention in existing, Western medicine for especially influenza therapeutic of catching a cold ineffective, healing time Longer technical problem is improved, and discloses a kind of effective flu decoction and preparation method thereof, the decoction have good effect, The less feature of repeatability, and this decoction preparation method is simple, and medicinal material is easy to get, and universality is stronger.
Invention content
It is an object of the invention to overcome the deficiencies of the prior art and provide a kind of flu decoction and preparation method thereof, with Solve it is existing in, western medicine treatment effect it is bad, treatment specific aim it is not strong, the technical problems such as preparation method complexity are improved, The present invention has the characteristics that healing flu effect is good, uneasy to recur.
The invention discloses following technical schemes;
The invention discloses a kind of flu decoctions, including following raw material:Mother chrysanthemum, safflower, cow-bezoar, sweet wormwood, bitter ground courage, gold and silver Flower, dried orange peel, Radix Glycyrrhizae and radix bupleuri.
Pharmacology analysis:
Mother chrysanthemum bitter, pungent, cool, clearing heat and detoxicating, wind-dispelling heat-dissipating dissipate the stasis of blood, improving eyesight, blood pressure lowering.Prevent influenza, sense It emits, treatment hypertension, hepatitis, dysentery, carbuncle furuncle treatment sore have positive effect;
Safflower is warm-natured, acrid flavour, invigorate blood circulation, removing blood stasis and analgesics, is conducive to prevent from having a stuffy nose obstructed;
Cow-bezoar is clearing heat and detoxicating, cures mainly abscess of throat, aphthae, ulcer serious case of furuncle;
Sweet wormwood bitter, it is pungent, it trembles with fear, the conversion ratio of lymphocyte can be improved, promote the immunization of body cell, leaching can be improved Bar transformation rate, promotes the immunization of body cell;
Bitter ground courage cool blood, heat-clearing, dehumidifying, Li Shui, removing toxic substances.Have effects that anti-inflammatory, only tears;
Honeysuckle contains the pharmacological components such as chlorogenic acid, cyanidenon glycosides, to hemolytic streptococcus, Staphylococcus aureus Etc. various pathogens and infection of the upper respiratory tract Causative virus etc. have stronger restraint, in addition can also strengthen immunity, Robust speaker feature, Protect liver, antitumor, anti-inflammatory, antipyretic, hemostasis (blood coagulation), inhibition intestinal absorption cholesterol etc.;
Dried orange peel is warm-natured, acrid flavour, bitter;With regulating qi-flowing for strengthening spleen, in tune, eliminating dampness, resolving sputum.Cure mainly the abdominal fullness and distention of the taste stagnation of the circulation of vital energy Or pain, indigestion.Abdominal distension uncomfortable in chest, indigestion and loss of appetite loose stool in wet turbid resistance.The cough and asthma of phlegm obstructing lung.For chest gastral cavity turgor, Deficiency of food is vomited and diarrhoea, coughing with a lot of sputum;
Radix Glycyrrhizae has anti-inflammatory, anti-allergic effects, can protect the throat and tunica mucosa tracheae of inflammation;
Radix bupleuri cold nature, bitter, pungent, return liver warp, gallbladder channel, tool soothing liver-gallbladder, thin gas solution is strongly fragrant, dissipates effect of fire.
Further, in order to preferably play the drug effect of various medicaments, the components by weight percent of the above raw material is:
The technical program also discloses a kind of preparation method of flu decoction, including following preparation process:
Step 1: being dried
Raw material mother chrysanthemum, safflower, cow-bezoar, sweet wormwood, bitter ground courage, honeysuckle, dried orange peel, Radix Glycyrrhizae and radix bupleuri are dried and are removed water Point;Screen out the non-medicinal dirt such as soil;
Step 2: effective component extracting
The mother chrysanthemum after drying, safflower and honeysuckle are weighed, is put into pot after grinding and is boiled with clear water, filters, takes filter Liquid;Then filter residue is carried out repeating to boil 2~3 times, merging filtrate obtains extracting solution A after concentration;
Cow-bezoar, dried orange peel and Radix Glycyrrhizae are pulverized with pulverizer respectively, in mass ratio 1:1:1 carries out proportioning mixing, obtains Mixed powder B;
It is put into the three-necked flask for being contained with ethanol solution after sweet wormwood, bitter ground courage and radix bupleuri are crushed, is heated to reflux stirring, After filtering, retains filtrate, obtain alcohol extract C;
Step 3: medicinal powder makes
After mixing by extracting solution A obtained, mixed powder B and alcohol extract C, be put into baking oven volatilize it is molten Agent obtains muffin D;
Step 4: pulverization process
The muffin D for evaporating solvent is poured into pulverizer and is crushed again, after crossing 250 mesh screens, flu medicinal powder is made;
Step 5: sterilization treatment
Flu medicinal powder obtained is carried out sterilization treatment after irradiating 24 hours under constant temperature with ultra violet lamp to be sealed Pouch-packaged;
Step 6: prepared by decoction
Parcel flu medicinal powder after sealing pouch-packaged is brewed with warm water, waits for that the flu medicinal powder fully dissolves Afterwards, you can take.This decoction is brewed by warm fire by carrying out a variety of Chinese herbal medicines, can carry out the active ingredient in herbal medicine abundant Dissolving, release can also evacuate internal cold air during warm is oral.
Further, the active ingredient in herbal medicine is volatilized in order to prevent, and moisture removal is dried to raw material in step 1 It is dried in vacuum drying chamber, the temperature in vacuum drying chamber is controlled at 55~60 DEG C.
Further, boiling time is long in order to prevent, the oxidation of oily matter in herbal medicine, by mother chrysanthemum, red in step 2 Flower and honeysuckle are put into after grinding in pot is boiled with clear water, stops heating, natural cooling after 5~10min of clear water boiling To room temperature.
Further, in order to more effectively extract the organic substance in drug, ethanol solution is mass concentration in step 2 For 75% ethanol solution, the temperature for being heated to reflux stirring is controlled at 85 DEG C.
Further, in order to preferably patient be facilitated to take according to quantity, the cold drug silty of pouch-packaged is sealed in step 5 Amount is 15~20 grams/bag.
The invention discloses a kind of flu decoction and preparation method thereof, the present invention in existing, Western medicine is for flu Especially influenza therapeutic is ineffective, the longer technical problem of healing time is improved, the decoction have good effect, The less feature of repeatability, and this decoction preparation method is simple, and medicinal material is easy to get, and universality is stronger.
Specific implementation mode
It elaborates below to the embodiment of the present invention, the present embodiment is carried out lower based on the technical solution of the present invention Implement, gives detailed embodiment and specific operating process, but protection scope of the present invention is not limited to following implementation Example.
Embodiment 1
Embodiment 1 discloses a kind of flu decoction, including following raw material:Mother chrysanthemum, safflower, cow-bezoar, sweet wormwood, bitter ground courage, gold Honeysuckle flower, dried orange peel, Radix Glycyrrhizae and radix bupleuri.Wherein, the components by weight percent of raw material is:7 parts of mother chrysanthemum, 15 parts of safflower, 9 parts of cow-bezoar, 3 parts of sweet wormwood, 18 parts of the courage in bitter ground, 15 parts of honeysuckle, 9 parts of dried orange peel, 9 parts of Radix Glycyrrhizae, 25 parts of radix bupleuri.
The present embodiment further includes following preparation process:
Step 1: being dried
Raw material mother chrysanthemum, safflower, cow-bezoar, sweet wormwood, bitter ground courage, honeysuckle, dried orange peel, Radix Glycyrrhizae and radix bupleuri are respectively put into vacuum and done Moisture removal is dried in dry case;Temperature in vacuum drying chamber is controlled at 55 DEG C.
Step 2: effective component extracting
The mother chrysanthemum after drying, safflower and honeysuckle are weighed, is put into pot after grinding and is boiled with clear water, filters, takes filter Liquid;Then filter residue is carried out repeating to boil 2 times, merging filtrate obtains extracting solution A after concentration;After each clear water boiling 10min i.e. Stop heating, is merged again after cooled to room temperature;
Cow-bezoar, dried orange peel and Radix Glycyrrhizae are pulverized with pulverizer respectively, in mass ratio 1:1:1 carries out proportioning mixing, obtains Mixed powder B;
It is put into and is contained in the ethanol solution that mass concentration is 75% after sweet wormwood, bitter ground courage and radix bupleuri are crushed, heated back The temperature of stream stirring is controlled at 85 DEG C, after filtering, is retained filtrate, is obtained alcohol extract C;
Step 3: medicinal powder makes
After mixing by extracting solution A obtained, mixed powder B and alcohol extract C, be put into baking oven volatilize it is molten Agent obtains muffin D;
Step 4: pulverization process
The muffin D for evaporating solvent is poured into pulverizer and is crushed again, after crossing 250 mesh screens, flu medicinal powder is made;
Step 5: sterilization treatment
Flu medicinal powder obtained is carried out sterilization treatment after irradiating 24 hours under constant temperature with ultra violet lamp to be sealed Pouch-packaged;The cold drug silty amount for sealing pouch-packaged is 15 grams/bag.
Step 6: prepared by decoction
Parcel flu medicinal powder after sealing pouch-packaged is brewed with warm water, waits for that the flu medicinal powder fully dissolves Afterwards, you can take.
Embodiment 2
Embodiment 2 discloses a kind of flu decoction, including following raw material:Mother chrysanthemum, safflower, cow-bezoar, sweet wormwood, bitter ground courage, gold Honeysuckle flower, dried orange peel, Radix Glycyrrhizae and radix bupleuri.Wherein, the components by weight percent of raw material is:10 parts of mother chrysanthemum, 18 parts of safflower, 8 parts of cow-bezoar, 8 parts of sweet wormwood, 22 parts of the courage in bitter ground, 18 parts of honeysuckle, 8 parts of dried orange peel, 8 parts of Radix Glycyrrhizae, 28 parts of radix bupleuri.
The present embodiment further includes following preparation process:
Step 1: being dried
Raw material mother chrysanthemum, safflower, cow-bezoar, sweet wormwood, bitter ground courage, honeysuckle, dried orange peel, Radix Glycyrrhizae and radix bupleuri are respectively put into vacuum and done Moisture removal is dried in dry case;Temperature in vacuum drying chamber is controlled at 60 DEG C.
Step 2: effective component extracting
The mother chrysanthemum after drying, safflower and honeysuckle are weighed, is put into pot after grinding and is boiled with clear water, filters, takes filter Liquid;Then filter residue is carried out repeating to boil 2 times, merging filtrate obtains extracting solution A after concentration;After each clear water boiling 5min i.e. Stop heating, is merged again after cooled to room temperature;
Cow-bezoar, dried orange peel and Radix Glycyrrhizae are pulverized with pulverizer respectively, in mass ratio 1:1:1 carries out proportioning mixing, obtains Mixed powder B;
It is put into and is contained in the ethanol solution that mass concentration is 75% after sweet wormwood, bitter ground courage and radix bupleuri are crushed, heated back The temperature of stream stirring is controlled at 85 DEG C, after filtering, is retained filtrate, is obtained alcohol extract C;
Step 3: medicinal powder makes
After mixing by extracting solution A obtained, mixed powder B and alcohol extract C, be put into baking oven volatilize it is molten Agent obtains muffin D;
Step 4: pulverization process
The muffin D for evaporating solvent is poured into pulverizer and is crushed again, after crossing 250 mesh screens, flu medicinal powder is made;
Step 5: sterilization treatment
Flu medicinal powder obtained is carried out sterilization treatment after irradiating 24 hours under constant temperature with ultra violet lamp to be sealed Pouch-packaged;The cold drug silty amount for sealing pouch-packaged is 20 grams/bag.
Step 6: prepared by decoction
Parcel flu medicinal powder after sealing pouch-packaged is brewed with warm water, waits for that the flu medicinal powder fully dissolves Afterwards, you can take.
Embodiment 3
Embodiment 3 discloses a kind of flu decoction, including following raw material:Mother chrysanthemum, safflower, cow-bezoar, sweet wormwood, bitter ground courage, gold Honeysuckle flower, dried orange peel, Radix Glycyrrhizae and radix bupleuri.Wherein, the components by weight percent of raw material is:11 parts of mother chrysanthemum, 18 parts of safflower, 6 parts of cow-bezoar, 8 parts of sweet wormwood, 26 parts of the courage in bitter ground, 20 parts of honeysuckle, 6 parts of dried orange peel, 6 parts of Radix Glycyrrhizae, 26 parts of radix bupleuri.
The present embodiment further includes following preparation process:
Step 1: being dried
Raw material mother chrysanthemum, safflower, cow-bezoar, sweet wormwood, bitter ground courage, honeysuckle, dried orange peel, Radix Glycyrrhizae and radix bupleuri are respectively put into vacuum and done Moisture removal is dried in dry case;Temperature in vacuum drying chamber is controlled at 55~60 DEG C.
Step 2: effective component extracting
The mother chrysanthemum after drying, safflower and honeysuckle are weighed, is put into pot after grinding and is boiled with clear water, filters, takes filter Liquid;Then filter residue is carried out repeating to boil 2~3 times, merging filtrate obtains extracting solution A after concentration;Each clear water boiling 5~ Stop heating after 10min, is merged again after cooled to room temperature;
Cow-bezoar, dried orange peel and Radix Glycyrrhizae are pulverized with pulverizer respectively, in mass ratio 1:1:1 carries out proportioning mixing, obtains Mixed powder B;
It is put into and is contained in the ethanol solution that mass concentration is 75% after sweet wormwood, bitter ground courage and radix bupleuri are crushed, heated back The temperature of stream stirring is controlled at 85 DEG C, after filtering, is retained filtrate, is obtained alcohol extract C;
Step 3: medicinal powder makes
After mixing by extracting solution A obtained, mixed powder B and alcohol extract C, be put into baking oven volatilize it is molten Agent obtains muffin D;
Step 4: pulverization process
The muffin D for evaporating solvent is poured into pulverizer and is crushed again, after crossing 250 mesh screens, flu medicinal powder is made;
Step 5: sterilization treatment
Flu medicinal powder obtained is carried out sterilization treatment after irradiating 24 hours under constant temperature with ultra violet lamp to be sealed Pouch-packaged;The cold drug silty amount for sealing pouch-packaged is 15~20 grams/bag.
Step 6: prepared by decoction
Parcel flu medicinal powder after sealing pouch-packaged is brewed with warm water, waits for that the flu medicinal powder fully dissolves Afterwards, you can take.
Typical case:
X is opened, women, 35 years old, Anhui Province Fuyang City people, government functionary usually seldom took exercise, regular cat fever, it The preceding usual oral western medicine pellet of flu, mostly flu will continue improve for 5-8 days;After taking this Chinese medicine flu decoction, two It can fully recover, and taking dose uses one day parcel, and boiling water brews oral.After taking, catch a cold without recurrent within two months Occur.
Mrs Li, people from Wuhu County 42 years old, do nurse's work, Influenza flu season, the flu state of an illness is heavier, is purchased to pharmacy in urban district Cold medicine is bought, is not felt any better slowly, also with low fever, after taking this decoction, is restored within 3 days normal.It wraps within one day one, boiling water punching Bubble, the same day can feel that nasal obstruction mitigates.
Guo, man, machinery plant worker, 29 years old, stature was sturdy, seldom fever flu, and Influenza flu season, flu is serious, takes Radix Isatidis granules without positive effect, after take Fufang Anfenwanan capsules and take after a week, flu improves, and after three days, flu is again Recurrence takes this decoction through friend recommendation, and early, evening respectively rushes one, and two days later, flu fully recovers, without fever in nearly two months Cold symptoms occur.
King XX, 13 years old, student, Influenza flu season was caught a cold illness by fever, is gone hospital's flu of having an intravenous drip to take a favorable turn, has been failed Full rehabilitation, occasionally there is clear nasal discharge, and after taking this flu decoction, boiling water brews decoction of catching a cold simply just before going to bed at night, restores just after three days Often.
This flu decoction is well-established by neighbouring group at present, and especially Influenza flu season, this decoction have been considered as house In standing medicine, the just gustation of this decoction is bitter, and a little honey can be added when brewing and take together, this decoction treat flu especially at present It is that have special effect, cure rate be more than ninety percent or more to influenza, absolutely effective, often takes few rebound phenomenons Occur.This drug carries out cooperation by production, study and research with Wannan Medical College at present, this is probed into come specific by the resources for research of colleges and universities In pharmaceutical formulation the effect of each drug.

Claims (7)

1. a kind of flu decoction, which is characterized in that including following raw material:Mother chrysanthemum, safflower, cow-bezoar, sweet wormwood, bitter ground courage, honeysuckle, Dried orange peel, Radix Glycyrrhizae and radix bupleuri.
2. flu decoction as described in claim 1, which is characterized in that the components by weight percent of the raw material is:
3. a kind of preparation method of flu decoction as claimed in claim 1 or 2, which is characterized in that including following preparation process:
Step 1: being dried
Processing is dried in raw material mother chrysanthemum, safflower, cow-bezoar, sweet wormwood, bitter ground courage, honeysuckle, dried orange peel, Radix Glycyrrhizae and radix bupleuri, is removed Moisture;
Step 2: effective component extracting
The mother chrysanthemum after drying, safflower and honeysuckle are weighed, is put into pot after grinding and is boiled with clear water, filters, takes filtrate;So Afterwards filter residue is carried out repeating to boil 2~3 times, merging filtrate obtains extracting solution A after concentration;
Cow-bezoar, dried orange peel and Radix Glycyrrhizae are pulverized with pulverizer respectively, in mass ratio 1:1:1 carries out proportioning mixing, is mixed Powder B;
It is put into the three-necked flask for being contained with ethanol solution after sweet wormwood, bitter ground courage and radix bupleuri are crushed, is heated to reflux stirring, filtered Afterwards, retain filtrate, obtain alcohol extract C;
Step 3: medicinal powder makes
After mixing by extracting solution A obtained, mixed powder B and alcohol extract C, it is put into baking oven and carries out solvent flashing, obtain To muffin D;
Step 4: pulverization process
The muffin D for evaporating solvent is poured into pulverizer and is crushed again, after crossing 250 mesh screens, flu medicinal powder is made;
Step 5: sterilization treatment
Flu medicinal powder obtained is subjected to sterilization treatment after being irradiated 24 hours under constant temperature with ultra violet lamp and is sealed pouch Packaging;
Step 6: prepared by decoction
Parcel flu medicinal powder after sealing pouch-packaged is brewed with warm water, after the flu medicinal powder fully dissolves, i.e., It can take.
4. the preparation method of flu decoction as claimed in claim 3, which is characterized in that done to the raw material in step 1 Dry that moisture removal is gone to be dried in vacuum drying chamber, the temperature in the vacuum drying chamber is controlled at 55~60 DEG C.
5. the preparation method of flu decoction as claimed in claim 3, which is characterized in that by mother chrysanthemum, safflower and gold in step 2 Honeysuckle flower is put into after grinding in pot to be boiled with clear water, stops heating, cooled to room temperature after 5~10min of clear water boiling.
6. the preparation method of flu decoction as claimed in claim 3, which is characterized in that ethanol solution described in step 2 is matter The ethanol solution for measuring a concentration of 75%, the temperature for being heated to reflux stirring are controlled at 85 DEG C.
7. the preparation method of flu decoction as claimed in claim 3, which is characterized in that seal pouch-packaged described in step 5 Cold drug silty amount be 15~20 grams/bag.
CN201810520233.2A 2018-05-28 2018-05-28 A kind of flu decoction and preparation method thereof Withdrawn CN108354995A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030027133A (en) * 2001-09-12 2003-04-07 최달정 The Method of Production an Natural Health Food or a Medicine for preventing and curing of Influenza Virus infection as to use Black Elderberry
CN101264162A (en) * 2008-04-10 2008-09-17 北京中泰天和科技有限公司 Proprietary Chinese medicine for treating wind-cold common cold and preparation technique
CN104274537A (en) * 2013-07-02 2015-01-14 天津药物研究院 Traditional Chinese medicine composition, and preparation method and application thereof
CN105497132A (en) * 2014-10-16 2016-04-20 宋淑芹 Chinese patent medicine for treating cold and preparation method of Chinese patent medicine

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030027133A (en) * 2001-09-12 2003-04-07 최달정 The Method of Production an Natural Health Food or a Medicine for preventing and curing of Influenza Virus infection as to use Black Elderberry
CN101264162A (en) * 2008-04-10 2008-09-17 北京中泰天和科技有限公司 Proprietary Chinese medicine for treating wind-cold common cold and preparation technique
CN104274537A (en) * 2013-07-02 2015-01-14 天津药物研究院 Traditional Chinese medicine composition, and preparation method and application thereof
CN105497132A (en) * 2014-10-16 2016-04-20 宋淑芹 Chinese patent medicine for treating cold and preparation method of Chinese patent medicine

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