CN101249226A - Traditional Chinese medicine preparation for curing madness disease - Google Patents

Traditional Chinese medicine preparation for curing madness disease Download PDF

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Publication number
CN101249226A
CN101249226A CNA2008101037188A CN200810103718A CN101249226A CN 101249226 A CN101249226 A CN 101249226A CN A2008101037188 A CNA2008101037188 A CN A2008101037188A CN 200810103718 A CN200810103718 A CN 200810103718A CN 101249226 A CN101249226 A CN 101249226A
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chinese medicine
radix
traditional chinese
medicine preparation
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CNA2008101037188A
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王信锁
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BEIJING WANSHOUTONG PHARMACEUTICAL TECHNOLOGY CORP
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BEIJING WANSHOUTONG PHARMACEUTICAL TECHNOLOGY CORP
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Priority to CNA2008101037188A priority Critical patent/CN101249226A/en
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Abstract

The invention relates to a traditional Chinese medicine preparation used to cure epilepsy. The traditional Chinese medicine preparation takes more than 10 species of Chinese herb medicines as the raw materials, such as gentian, scutellaria, fructus gardenia, plantain seed, etc., and has the efficacies of clearing heat from liver and eliminating phlegm for resuscitation. The invention is formed by combining the latest achievements in scientific research with the traditional Chinese medicine syndrome differentiation and treatment. The invention aims to provide the traditional Chinese medicine preparation used to cure the epilepsy. The traditional Chinese medicine preparation used to cure the epilepsy has the advantages of obvious curative effect, convenient and safe usage, no side effects and low cost.

Description

A kind of Chinese medicine preparation for the treatment of the epilepsy disease
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of the epilepsy disease, is that a kind of epilepsy disease for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
The epilepsy disease is by expectorant, fire, the stasis of blood, and congenital factors etc., and it is disorderly contrary to cause QI and blood, and clear key is hoodwinked and fallen ill, suddenly falling forward dusk, tonic seizure, when moving from waking up, the back characteristic of human nature's as usual that wakes up paroxysmal disease.Mainly refer to epilepsy, comprise constitutional and secondary epilepsy.The formation of primary disease, after how unusual, brain wound or his disease by incoordination of seven emotions, eating and drinking without temperance, natural endowment, zang-fu disharmony, the turbid retardance of expectorant, mechanism of qi is disorderly contrary, in the wind sun moving due to.And it is the most important to haunt with the expectorant heresy especially.The expectorant gather qi together is contrary, and wind-phlegm impatency then epilepsy is sent out; The expectorant sending down the abnormal ascending QI stops along then returning temporarily.Dialectical generally real from the beginning of how, how empty send out for a long time QI-insufficiency person positive, but normal apoplexy due to deficiency has reality.Treatment must this deficiency and excess of minute mark.Generally from the beginning of or frequent stage of attack, the domination of pathogen is main person, Ying Congbiao controls, with dissipating phlegm and regulating QI, it is main that endogenous wind stopping is had one's ideas straightened out, and eliminates the phlegm and focus on.Inclined to one side phlegm-fire person, suitable removing heat-phlegm; The real accumulation and obstruction of sputum person of body can tell down by expectorant; Former thereby companion's blood stasis person such as wound can cooperate the clots absorbing that reduces phlegm.Send out for a long time and cause void, positive QI-insufficiency, heart kidney two loses, and controls suitable invigorating heart and kidney, invigorating the spleen for dissipating phlegm, giving consideration to both the incidental and fundamental.Simultaneously, primary disease is also worked as pay attention to taking good care of oneself spirit, diet, is avoided work and rest immoderate.The traditional Chinese medical science divides syndrome of phlegm-fire disturbing mind, the pneumatic card of blood deficiency, wind-phlegm to close disease type Coryza Treated by Syndrome Differentiation such as key card, syndrome of blood stasis blocking brain, syndrome of deficiency of both heart and spleen, syndrome of yin deficiency of liver and kidney clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of the epilepsy disease.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by following raw materials by weight proportions:
0.1~2 part of 1.5~6 parts of Radix Scutellariae of 1.5~6 parts of Lapis Chloriti of Pumex
0.1~2 part of 1.0~4 parts of Radix Bupleuri of 1.0~4 parts of Radix Rehmanniae of Fructus Gardeniae (parched)
0.1~2 part of 1.0~4 portions of Rhizoma Coptidis of 1.0~4 parts of Radix Angelicae Sinensis of Rhizoma Alismatis
0.1~2 part of 0.1~2 part of Caulis Bambusae In Taenia of 0.1~2 portion of Semen Plantaginis of Radix Gentianae.
The weight proportion of each crude drug of optimization formula of the present invention is:
0.5~1.5 part of 2.5~3.5 parts of Radix Scutellariae of 2.5~3.5 parts of Lapis Chloriti of Pumex
0.5~1.5 part of 1.5~2.5 parts of Radix Bupleuri of 1.5~2.5 parts of Radix Rehmanniae of Fructus Gardeniae (parched)
0.5~1.5 part of 1.5~2.5 portions of Rhizoma Coptidis of 1.5~2.5 parts of Radix Angelicae Sinensis of Rhizoma Alismatis
0.5~1.5 part of 0.5~1.5 part of Caulis Bambusae In Taenia of 0.5~1.5 portion of Semen Plantaginis of Radix Gentianae.
The weight proportion of each crude drug of optimum formula of the present invention is:
1 part of 3 parts of Radix Scutellariae of 3 parts of Lapis Chloriti of Pumex
1 part of 2 parts of Radix Bupleuri of 2 parts of Radix Rehmanniae of Fructus Gardeniae (parched)
1 part of 2 portions of Rhizoma Coptidis of 2 parts of Radix Angelicae Sinensis of Rhizoma Alismatis
1 part of 1 part of Caulis Bambusae In Taenia of 1 portion of Semen Plantaginis of Radix Gentianae.
Drug action mechanism among the present invention is as follows:
The Pumex property of medicine is salty, and is cold.Return lung, kidney channel.Has removing heat from the lung and dissipating phlegm, relieving stranguria by diuresis, the effect of hard masses softening and resolving.Can treat phlegm-heat obstructing in the lung, the thick difficulty of cough with asthma expectorant is coughed up, the puckery pain of dribbling urination, goiter scrofula etc.(the 2763rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Lapis Chloriti nature and flavor are sweet, salty, and are flat.Return lung, the heart, Liver Channel.Has the expectorant of the bob therapeutic method to keep the adverse QI flowing downwards, the effect of checking hyperfunction of the liver for relieving convulsion.Can treat the pertinacious phlegm gluing, the cough with dyspnea dyspnea with rapid respiration, epilepsy is gone mad, and is irritated uncomfortable in chest, convulsion with spasms etc.(the 159th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Fructus Gardeniae (parched) property of medicine hardship, cold.GUIXIN, liver, lung, stomach, tri-jiao channel.Has the pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, the effect of removing pathogenic heat from blood and toxic substance from the body.It is vexed to treat calentura, the liver-fire conjunctival congestion, and headache, jaundice due to damp-heat, stranguria is spitted blood, epistaxis, dysentery, hematuria, aphtha of the mouth and tongue, sore swollen toxin is sprained and is swollen and ache etc.(the 2242nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea , mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Gentianae nature and flavor hardship, cold.Return liver, gallbladder meridian.Have eliminating pathogen in the liver gallbladder fire, the clear part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels is wet, relieving convulsion making eye bright, and the malaria protozoon is good for the stomach, the effect that protects the liver.Can treat that Liver Channel intenseness of heat, infantile convulsion are manic, encephalitis B, headache, conjunctival congestion, pharyngalgia, jaundice, hematodiarrhoea, the swollen skin infection of pain, scrotum swell and ache, pudendum pruritus due to damp pathogen, hypertension, dizziness and tinnitus, chest and hypochondrium, acute infectious hepatitis, cystitis, skin infection swell and ache etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 413rd page).
The Semen Plantaginis property of medicine is sweet, light, is slightly cold.Return lung, liver, kidney, urinary bladder channel.Have heat clearing away, diuresis makes eye bright, the expectorant effect.Can treat urinary obstruction, stranguria with turbid discharge, leukorrhagia, edema, the heat-damp in summer dysentery, conjunctival congestion is hidden from view, and the expectorant heat syndrome cough is breathed heavily etc.(the 539th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Scutellariae property of medicine hardship, cold.Return lung, the heart, liver, gallbladder, large intestine channel.Has clearing away heat-fire, dampness detoxifcation, hemostasis, antiabortive effect.Can treat the cough due to lung-heat, the calentura unconsciousness due to high fever, the liver-fire headache, conjunctival congestion and swelling pain, jaundice due to damp-heat, dysentery, pyretic stranguria is told nosebleed, metrorrhagia, excessive fetal movement due to heat in pregnancy, carbuncle furuncle etc.(the 2808th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Bupleuri nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Effect with reconciling superficies and interior, soothing the liver, yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).
Rhizoma Coptidis nature and flavor hardship, cold.GUIXIN, liver, stomach, large intestine channel.Has clearing away heat-fire, dampness, antidotal effect.Can treat the calentura heresy and go into the hyperpyrexia of heart channel, agitation, delirium or the absurd row of intenseness of heat forcing blood tell nosebleed, the damp and hot feeling of stuffiness in chest is had loose bowels, dysentery, the vexed insomnia of hyperactivity of heart-fire, gastropyretic vomiting, rapid digestion of food and polyorexia, liver-fire conjunctival congestion and swelling pain, and pathopyretic ulcer, the furunculosis septicemia, gingival swelling and pain, aphtha of the mouth and tongue, hemorrhoidal bleeding, eczema is scalded etc.(the 2818th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Caulis Bambusae In Taenia property of medicine is sweet, is slightly cold.Return spleen, stomach, gallbladder meridian.Have removing heat-phlegm, relieve restlessness and prevent vomiting, the effect of antiabortive removing heat from blood.Can treat the cough due to lung-heat, the dysphoria with smothery sensation palpitation with fear, gastric heat is vomitted oh, pregnancy reactions, frequent fetal movement is spitted blood epistaxis, hematuria, metrorrhagia etc.(the 1244th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Pumex, Lapis Chloriti and Radix Gentianae; With Radix Scutellariae, Fructus Gardeniae (parched), Radix Rehmanniae, Rhizoma Alismatis, Radix Angelicae Sinensis and Rhizoma Coptidis is ministerial drug; With Semen Plantaginis, Radix Bupleuri and Caulis Bambusae In Taenia is adjuvant.All medicines are harmonious, and are total to the tool purging liver-fire, the effect of waking up the patient from unconsciousness by dissipating phlegm.Treatment epilepsy disease has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged;
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment epilepsy disease of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat the epilepsy disease, and the prevention of epilepsy disease is also had good effect, and treatment epilepsy disease has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to treatment epilepsy disease; Treatment epilepsy patient 44 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.34 examples of fully recovering account for 77.27%, and 8 examples that take a turn for the better account for 18.18%, and more 2 examples do not account for 4.55%, and total effective rate reaches 95.45%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
Embodiment 1 decoction is pressed following weight weighting raw materials:
1 part of 3 parts of Radix Scutellariae of 3 parts of Lapis Chloriti of Pumex
1 part of 2 parts of Radix Bupleuri of 2 parts of Radix Rehmanniae of Fructus Gardeniae (parched)
1 part of 2 portions of Rhizoma Coptidis of 2 parts of Radix Angelicae Sinensis of Rhizoma Alismatis
1 part of 1 part of Caulis Bambusae In Taenia of 1 portion of Semen Plantaginis of Radix Gentianae.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment epilepsy disease that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.
Embodiment 2 capsules are pressed following weight weighting raw materials:
1 part of 3 parts of Radix Scutellariae of 3 parts of Lapis Chloriti of Pumex
1 part of 2 parts of Radix Bupleuri of 2 parts of Radix Rehmanniae of Fructus Gardeniae (parched)
1 part of 2 portions of Rhizoma Coptidis of 2 parts of Radix Angelicae Sinensis of Rhizoma Alismatis
1 part of 1 part of Caulis Bambusae In Taenia of 1 portion of Semen Plantaginis of Radix Gentianae.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, decoct with water twice, 1.5~2 hours for the first time, 0.5~1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree~85 when spending, the clear paste of relative density 1.08~1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when 50 degree~55 are spent, be concentrated into the clear paste of relative density 1.30~1.32, drying, be ground into fine powder, incapsulate.Adorn 0.3 gram for every, usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2~10, two 2 to three times on the one, three months is a course of treatment.

Claims (3)

1. Chinese medicine preparation for the treatment of the epilepsy disease is characterized in that it is made by following raw materials by weight proportions:
0.1~2 part of 1.5~6 parts of Radix Scutellariae of 1.5~6 parts of Lapis Chloriti of Pumex
0.1~2 part of 1.0~4 parts of Radix Bupleuri of 1.0~4 parts of Radix Rehmanniae of Fructus Gardeniae (parched)
0.1~2 part of 1.0~4 portions of Rhizoma Coptidis of 1.0~4 parts of Radix Angelicae Sinensis of Rhizoma Alismatis
0.1~2 part of 0.1~2 part of Caulis Bambusae In Taenia of 0.1~2 portion of Semen Plantaginis of Radix Gentianae.
2. a kind of Chinese medicine preparation for the treatment of the epilepsy disease according to claim 1, wherein the weight proportion of each crude drug is:
0.5~1.5 part of 2.5~3.5 parts of Radix Scutellariae of 2.5~3.5 parts of Lapis Chloriti of Pumex
0.5~1.5 part of 1.5~2.5 parts of Radix Bupleuri of 1.5~2.5 parts of Radix Rehmanniae of Fructus Gardeniae (parched)
0.5~1.5 part of 1.5~2.5 portions of Rhizoma Coptidis of 1.5~2.5 parts of Radix Angelicae Sinensis of Rhizoma Alismatis
0.5~1.5 part of 0.5~1.5 part of Caulis Bambusae In Taenia of 0.5~1.5 portion of Semen Plantaginis of Radix Gentianae.
3. a kind of Chinese medicine preparation for the treatment of the epilepsy disease according to claim 1, wherein the weight proportion of each crude drug is:
1 part of 3 parts of Radix Scutellariae of 3 parts of Lapis Chloriti of Pumex
1 part of 2 parts of Radix Bupleuri of 2 parts of Radix Rehmanniae of Fructus Gardeniae (parched)
1 part of 2 portions of Rhizoma Coptidis of 2 parts of Radix Angelicae Sinensis of Rhizoma Alismatis
1 part of 1 part of Caulis Bambusae In Taenia of 1 portion of Semen Plantaginis of Radix Gentianae.
CNA2008101037188A 2008-04-10 2008-04-10 Traditional Chinese medicine preparation for curing madness disease Pending CN101249226A (en)

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Application Number Priority Date Filing Date Title
CNA2008101037188A CN101249226A (en) 2008-04-10 2008-04-10 Traditional Chinese medicine preparation for curing madness disease

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CN101249226A true CN101249226A (en) 2008-08-27

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CNA2008101037188A Pending CN101249226A (en) 2008-04-10 2008-04-10 Traditional Chinese medicine preparation for curing madness disease

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106729098A (en) * 2017-01-03 2017-05-31 张先军 A kind of Chinese medicine composition for treating epilepsy

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106729098A (en) * 2017-01-03 2017-05-31 张先军 A kind of Chinese medicine composition for treating epilepsy

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Open date: 20080827