CN101248880B - Fatigue resistant sport drink and method of preparing the same - Google Patents

Fatigue resistant sport drink and method of preparing the same Download PDF

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CN101248880B
CN101248880B CN2008100905056A CN200810090505A CN101248880B CN 101248880 B CN101248880 B CN 101248880B CN 2008100905056 A CN2008100905056 A CN 2008100905056A CN 200810090505 A CN200810090505 A CN 200810090505A CN 101248880 B CN101248880 B CN 101248880B
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詹华强
董婷霞
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Hong Kong University of Science and Technology HKUST
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Abstract

The invention discloses a sports beverage with anti-fatigue effect, and a preparation method. The sports beverage is prepared from (by weight parts) astragalus membranaceus 1-30, angelica sinensis 1-30, rhodiola sacra 1-30, and water 400-1,000. The inventive sports beverage can supplement water, sugar and electrolyte consumed when a person is playing sports. Also, the results of cell and animal experiments show that the inventive sports beverage has the effects of resisting oxidation, protecting cells, resisting sports fatigue, and improving sports ability.

Description

A kind of fatigue resistant sport drink and preparation method thereof
Technical field
The present invention relates to a kind of sports drink, particularly a kind of sports drink of tool antifatigue effect.
Background technology
" exercise makes one strong ", the modern more and more payes attention to improving through sports the quality of health, also more and more pays close attention to the recovery of motion back physical function and the elimination of exercise induced fatigue simultaneously.The 5th boundary's international movement biochemistry meeting exercise induced fatigue is defined as " the physical function physiology course can not continue a certain specified level with (or) each organ can not keep a kind of state of its predetermined exercise intensity ".The reason that causes exercise induced fatigue mainly is consuming excessively of energy substance, the accumulation in vivo of tired material, acid-base balance, osmotic pressure balance, isorrheic imbalance in the body.At present on the market sports drink mainly be through keep the skin wet, sugar and electrolyte, add chemicals and reach the effect that improves locomitivity, eliminates fatigue with biological products.But the side effect of chemicals and biological products may cause certain harm to body, and some drugs also contains the excitant composition, therefore seeks the research focus that safe and effective antifatigue food and medicine have become the sports medical science research field.
Traditional Chinese medicine belongs to the category of " overstrain internal injury " to " exercise induced fatigue " as traditional medicine and culture of health preserving, and " element is asked and lifted the pain opinion " has cloud " overstrain may lead to decline of vital energy ", " the deficient beautiful letter outline of gold is collected literary composition " cloud " its essence and blood of Lao Zebilao also ".Overstrain is felt frustrated, and deficiency of vital energy fortune blood is weak and hematogenous blockage causes blood stasis, channels and collaterals discord, thereby symptoms such as DOMS, bone be weak occur.According to the legislation rules of treatment of " treatinging deficiency with tonification ", should set up " reinforcing method " to resist, thereby use Chinese medicine resisted motion fatigue often to start with at present from " subsidy yang-energy "; Hold concurrently with compensate qi and blood; Through the smart Tianjin of tonifying Qi and blood, regulate organs function, help the recovery of overstrain internal injury; Eliminate exercise induced fatigue rapidly, recover physical function.Many modern study results also show, help class Chinese medicine can promote exercise induced fatigue elimination, improve locomitivity.Developing traditional help class Chinese medicine has broad application prospects and huge market efficiency as sports tonica.
Summary of the invention
The object of the present invention is to provide the traditional traditional Chinese medical science principles of formulating prescriptions of foundation, have fatigue resistant sport drink that contains the Chinese medicine constituents of definite antifatigue effect and preparation method thereof.
Technical solution of the present invention is: a kind of fatigue resistant sport drink, it comprises the raw material components of following weight parts, 1~30 part of the Radix Astragali, 1~30 part of Radix Angelicae Sinensis, 1~30 part of rhodiola root, 400~1000 parts in water.
It also comprises the taurine of 0.1~1 weight portion.
Preferred ingredients is: the Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion, water 650 weight portions.
The above-mentioned raw materials composition can add materials such as flavor enhancement, electrolyte, vitamin, amino acid.
A kind of fatigue resistant sport drink preparation technology method of the present invention is: the Radix Astragali, Radix Angelicae Sinensis are added 8 times of water gaging heating and extracting 2 times, and each 1 hour, extract merged, and filtered, and filtrating is concentrated into 14 times that are equivalent to the medicinal material amount, and is subsequent use; Rhodiola root medicinal material steam distillation is collected the distillate that is equivalent to 3 times of medicinal material amounts, and is subsequent use; The dregs of a decoction add 8 times of water gagings and extract 2 times, and each 1 hour, extract merged, and filtered; Filtrating is concentrated into 2 times that are equivalent to the medicinal material amount, and it is 66% to containing the alcohol amount that concentrate adds ethanol, fully stirs the back hold over night, filters; Filtrating adds isopyknic aqueous solution that contains 1% gelatin, and fully stirs 20 minutes, filters; Filtrate recycling ethanol is concentrated into 2 times that are equivalent to the medicinal material amount, and is subsequent use; With the above-mentioned Radix Astragali, angelica extract, rhodiola root steam distillation liquid, rhodiola extract mixing, promptly get.
Preferred scheme is with the Radix Astragali, angelica extract, rhodiola root steam distillation liquid, rhodiola extract mixing, to add taurine; Add flavor enhancements such as sweetener, essence and acid, electrolyte and vitamins such as sodium, potassium, magnesium, calcium, amino acid; Add the water mixing, promptly get.
The rhodiola root medicinal material is used steam distillation, mainly extracts rhodiola root special delicate fragrance smell; Add isopyknic aqueous solution that contains 1% gelatin, be mainly the astringent taste composition tannin of removing in the rhodiola root medicinal material, make the mouthfeel of beverage better.
Sports drink prescription of the present invention adds compositions such as taurine and electrolyte, vitamin, flavor enhancement by the Radix Astragali, Radix Angelicae Sinensis, rhodiola root three flavor Chinese medicines.Wherein the Radix Astragali, Radix Angelicae Sinensis are the prescription flavour of a drug that gold dollar is cured the blood-enrich name side danggui buxue decoction that tame Lee east wall creates, and two medicines have the effect of benefiting qi for promoting production of blood with 5: 1 score composition of prescription, are used for controlling the overstrain internal injury, diseases such as asthenia of qi and blood more.Modern pharmacological research shows, by the Radix Astragali, when the danggui buxue decoction that is grouped into has enhance immunity, promotes hematopoiesis function, the protection cardiovascular and cerebrovascular, protect the liver, effect such as anti-oxidant.Rhodiola root has nourishing blood and tranquilization, effect such as promoting blood circulation and removing blood stasis, for deficiency of vital energy and physically weak, weak, the palpitation and insomnia of losing heart, dizzy disease such as dizzy better therapeutic effect is arranged.Big quantity research shows that rhodiola root has the keto consumpting speed of reduction, increases exercise tolerance, strengthens the glycogen deposit, improves the aerobic metabolism process of important organs such as heart and brain, and enhancing body is a kind of Chinese medicine sports tonica commonly used to the pharmacological actions such as tolerance of low-oxygen environment.Test cell line is the result show: danggui buxue decoction and gadol extract make up both Radixs Astragali with the ratio of (1: 3): Radix Angelicae Sinensis: rhodiola root medicinal material weight ratio is 5: 1: 3 o'clock, and it is anti-oxidant best with protective effect effect cell.Taurine is a kind of beta amino acids of sulfur-bearing, and it has BA widely as a kind of conditionity essential amino acid in the human body, is the important substance of regulating the body normal physiological function.Research shows, taurine because of its to the Radical Metabolism in the motion body, Ca 2+Transhipment etc. has good regulating action, thereby shows good anti-sports fatigue effect.More than four flavors, all have the material of anti-fatigue effect.Innovation part of the present invention is not only to have kept advantages such as general motion beverage supplementing water, electrolyte, sugar, vitamin; And based on further investigation to traditional traditional Chinese medical science principles of formulating prescriptions; In conjunction with the modern pharmacological research achievement; The material of choosing the Radix Astragali, Radix Angelicae Sinensis, rhodiola root, four kinds of definite anti-fatigue effects of tool of taurine is processed the sports drink of tool anti-fatigue effect as sports tonica through scientific composition.
For confirming the pharmacological action of sports drink of the present invention, we have designed H 2O 2Induce cell protection test, mouse swimming with a load attached to the body test, the power of damage exhaust the anti-anoxic experiment of mensuration, mouse rotating stick test, mouse normal pressure of serum urea nitrogen, lactic dehydrogenase and the hepatic glycogen of model mice, to a series of pharmacological testings such as influence of mouse content of hemoglobin, for beverage of the present invention is eliminated exercise induced fatigue, recovers physical function, improved pharmacological action such as locomitivity experimental basis is provided.
The raising of exercise tolerance is the performance that anti-fatigue ability is strengthened, and the length of swimming time can reflect the degree that animal movement is tired.The swimming time of fatigue resistant sport drink high dose successive administration ability significant prolongation animal, prompting has the effect that strengthens the anti-sports fatigue of animal.When muscle acutely shrinks,, must quicken glucolytic energy supply process because of the oxygen supply deficiency is depended merely on the requirement that aerobic oxidation can not be satisfied energy.Under the anaerobic situation, muscle has also produced a large amount of lactic acid when obtaining energy through glycolysis reaction, lactic acid dissociate that the hydrogen ion that generates accounts for that the muscle middle acid substance dissociates more than 85%.The increase of lactic acid makes hydrogen ion concentration rising in the muscle, and pH descends, and then causes a series of biochemical variations, is to cause tired major reason.So can reduce the material of blood lactic acid content, can play and reduce tired effect.The content of serum urea nitrogen is in linear relation with motion, its in vivo accumulate the lot of consumption with the human body energy material, be a major reason that causes exercise induced fatigue.Research shows that body serum urea nitrogen content increases with the increase of work and exercise load, and body is poor more to load performance, and the increase of serum urea nitrogen is just obvious more.Sero-enzyme LDH is one of important detection index of human body energy metabolism, can reflect the degree of injury of motion to the cells of organs film.Fatigue resistant sport drink can significantly reduce long-time swimming and the animal blood serum urea nitrogen that power exhausts and the level of lactic dehydrogenase occur, points out it to have the generation that suppresses exercise induced fatigue.Simultaneously, tired generation is relevant with the sugar (blood sugar and glycogen) of interior two types of body.Hepatic glycogen is exhausted during body strenuous exercise, and gluconeogenesis is suppressed, and blood sugar concentration reduces, and can make central nervous system generation interference and occur tired.The deposit of hepatic glycogen increases in the liver, blood sugar level in the time of can keeping motion, thus for providing more energy, body reaches the purpose of antifatigue.Sports drink of the present invention can strengthen the ability of animal antifatigue through the hepatic glycogen deposit that improvement power exhausts model.
Anoxic is a kind of pernicious stimulation to body, can influence the various metabolism of body, finally can cause the vitals anoxics such as heart and brain of body, and energy supply is not enough and death.Content of hemoglobin and exercise tolerance and anti-anoxic are in close relations.Erythremia has made things convenient for carrying of oxygen simultaneously, can satisfy the needs of body to oxygen, reduces accumulating of lactic acid, reduces organism fatigue.Sports drink of the present invention is to normal mouse normal pressure hypoxia-bearing capability and the normal mouse content of hemoglobin is not had obvious influence, but the high dose successive administration can significantly improve erythrocytic quantity.
Experiment strengthens the effect of mouse anti-reflecting fatigue from different aspect research fatigue resistant sport drinks; The results suggest fatigue resistant sport drink maybe be through biochemistry, the energetic supersession that improves animal; Increase approach such as erythrocyte number and strengthen the animal fatigue resistance, for it is used to eliminate exercise induced fatigue, recovers physical function, improves locomitivity experimental basis is provided.
Description of drawings
Accompanying drawing 1 is induced the protective effect effect contrast figure of the PC12 cell of damage for danggui buxue decoction (DBT) and rhodiola root to H2O2;
Accompanying drawing 2 strengthens danggui buxue decoction (DBT) for taurine and rhodiola root is induced the protective effect effect contrast figure of the PC12 cell of damage to H2O2.
The specific embodiment
The action effect of this sports drink antifatigue is described through concrete experimental example below:
Experimental example one: to H 2O 2Induce the protective effect of the PC12 cell of damage
1.1 material: the PC12 cell is purchased in the US mode bacterial classification and is collected center (ATCC);
NBCS, DMEM culture medium dry powder (U.S. Gibco company);
H 2O 2, MTT (U.S. Sigma company);
12 well culture plates (Denmark NUNC company);
NU2500E type CO2 incubator (Britain Forma Scientif company);
The Chinese medicine sample that is tried is provided by biology department of Hong Kong University of Science and Thchnology and development of Chinese herb products center.
1.2 method
(1), the cultivation of PC12 cell: culture medium is 37 ℃ of DMEM culture mediums that contain 10% hyclone, 100U/ml penicillin and 100 μ g/ml streptomysins, 50mL/L CO 2The conventional cultivation.Treat that cell covers with to blake bottle floor space 80%, add and tried the Chinese medicine sample, add H after the 2hr 2O 2, adding physiological saline is negative control, the positive contrast of Vitamin C
(2), the detection of PC12 cell survival rate: adopt violet staining (MTT) method to detect.
1.3 data processed result is all represented with mean ± standard deviation, and with the t check experimental data is carried out statistical analysis.
1.4 result of the test
Consult accompanying drawing 1, danggui buxue decoction (DBT) and rhodiola root are to H 2O 2Induce the protective effect effect comparison of the PC12 cell of damage, the antioxidation of the rhodiola root of this test main research danggui buxue decoction and different proportion, hydrogen peroxide (H 2O 2) can make the PC12 cell impaired, when anticipating the PC12 cell with different prescription Chinese medicine, the Chinese medicine with anti-oxidation efficacy can reduce hydrogen peroxide (H 2O 2) impaired to the PC12 cell.Wherein with the proportioning of danggui buxue decoction and rhodiola root (1: 3), anti-oxidant and the cytoprotection effect is best to PC12.
Consult Fig. 2; Taurine enhancing danggui buxue decoction (DBT) and rhodiola root are induced the protective effect effect comparison of the PC12 cell of damage to H2O2; As can be seen from the figure; When being aided with taurine, danggui buxue decoction, rhodiola root and taurine are with the proportioning of (1: 3: 0.3), and its cytoprotection effect effect to PC12 is best.
Experimental example two: mouse swimming with a load attached to the body test
2.1 test material
2.1.1 given the test agent: sports drink magma of the present invention (containing the Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion): 12.4g medicine/50ml is provided by biology department of Hong Kong University of Science and Thchnology and development of Chinese herb products center.
2.1.2 positive control drug: QINGCHUN BAO antiageing tablet (primary raw material is red ginseng, radix rehmanniae recen, asparagus fern, the tuber of dwarf lilyturf, the root bark of Chinese wolf-berry, Poria cocos): the 0.3g/ grain, the honest youth is protected pharmaceutcal corporation, Ltd's (lot number: 0610001)
2.1.3 test dose: sports drink prescription is 12.4g crude drug/1000ml beverage, and the adult drinks 500ml at every turn, i.e. 6.2g crude drug/people/inferior, and to become body weight for humans 60kg, i.e. 0.1g crude drug/kg/ time.Basic, normal, high three dose groups of this test mice; Be made as 1,2 respectively, 4g crude drug/kg; Be equivalent to 4,8,16ml concentrate/kg, for the adult drinks 10,20,40 times (according to the weight) of dosage, medication---get concentrate 2,4,8ml respectively; Thin up is irritated stomach after becoming 10ml, and irritating the stomach amount is the 0.2ml/10g body weight.Positive control drug QINGCHUN BAO antiageing tablet is the 0.1g/kg body weight, is 10 times of clinical medicine dose.
2.1.4 animal: NIH mouse (Guangdong Province's Experimental Animal Center provides), the quality certification number: SCXK (Guangdong) 2003-0002.
2.2 method and result:
Get 60 of NIH mouse, male and female half and half, body weight 18-22g is divided into 5 groups, i.e. blank (H at random 2O) group, QINGCHUN BAO antiageing tablet positive controls, the basic, normal, high dosed administration group of sports drink, 12 every group.Press dosage gastric infusion every day 1 time of table 1, blank control group waits the distilled water of capacity, continuous 7 days; After the last administration 1 hour; At iron hoop that is equivalent to mouse body weight 10% of mouse tail bundle, mouse is put into depth of water 23cm respectively, in the pond that water temperature is 20 ± 1 ℃; The time of record mouse from beginning to swim and exhaust to muscle power can not the person of emerging serve as that muscle power is exhausted with mouse head submerged 10s.The difference of mouse swimming time is respectively organized in the t check.The result sees table 1.
Table 1 crude drug is to the influence of mouse swimming endurance
Figure S2008100905056D00062
Annotate: compare * P<0.05, * * P<0.01 with blank control group.
Medicine is to the influence of mouse swimming endurance: compare with the blank group, the continuous gastric infusion of sports drink high dose can obviously prolong the mouse swimming time and promptly significantly improve the mouse fatigue proof ability of swimming, and significant difference (P<0.05) is arranged.QINGCHUN BAO antiageing tablet, the low middle dosed administration of sports drink all have the mouse swimming time of prolongation but no difference of science of statistics (P>0.05).The heavy dose of administration of results suggest sports drink can improve the fatigue proof degree of animal, and effect is superior to the QINGCHUN BAO antiageing tablet.
Experimental example three: power exhausts the mensuration of serum urea nitrogen, lactic dehydrogenase and the hepatic glycogen of model mice
3.1 test material:
3.1.1 laboratory apparatus: 7200 type You Nike ultraviolet specrophotometers.
3.1.2 kit: urea nitrogen (BUN), lactic dehydrogenase (LDH) kit are provided by the middle north control bio tech ltd of giving birth to.
Surplus with experimental example 1
3.2 method and result:
Get 72 of mouse, male and female half and half, body weight 18-22g is divided into 6 groups at random, i.e. blank group (only irritate clothes equal-volume distilled water, the power of not making exhausts model), model group, QINGCHUN BAO antiageing tablet positive controls, the basic, normal, high administration group of sports drink, 12 every group.Each organizes gastric infusion dosage with 2.1, blank control group and model group to etc. the distilled water of capacity, successive administration 7 days, the last administration is after 1 hour, except that blank control group, all the other 5 groups of mouse are put into depth of water 23cm, 90min swims in the pond that water temperature is 25 ± 1 ℃.Take out mouse, eye socket is got blood, and separation of serum is surveyed serum urea nitrogen (BUN), serum lactic dehydrogenase (SLDH) (LDH) content.Dissect mouse, get part liver tissue homogenate, survey liver glycogen content.Add up and respectively organize the difference of mice serum urea nitrogen, blood lactic acid, liver glycogen content.The result sees table 2.
Table 2 crude drug to power exhaust model mice serum urea nitrogen, lactic dehydrogenase enzyme level and hepatic glycogen content influence
Figure S2008100905056D00071
Figure S2008100905056D00072
Annotate: model group and blank control group group be * P<0.05 relatively, * * P<0.01; Administration group and model group compare, #P<0.05, ##P<0.01.
Medicine exhausts the influence of model mice biochemical metabolism to power: compare with blank control group; The level of model group animal blood serum urea nitrogen, lactic dehydrogenase significantly raises and hepatic glycogen content descends (P<0.05 or P<0.01); The long-time swimming of prompting back animal metabolism product increases, and the muscle power consume is serious; Compare with model group, the level of QINGCHUN BAO antiageing tablet positive controls animal blood serum urea nitrogen, lactic dehydrogenase is lower than model group, and hepatic glycogen content is higher than model group, but equal no difference of science of statistics (P>0.05); The content that sports drink low dosage administration treated animal serum urea nitrogen level is lower than model group, hepatic glycogen is higher than model group, but also no difference of science of statistics (P>0.05); Dosed administration treated animal serum urea nitrogen, lactic dehydrogenase also have reduction in the sports drink, but no difference of science of statistics (P>0.05) has significant difference (P<0.05) and hepatic glycogen content is higher than model group; Sports drink high dose administration treated animal serum lactic dehydrogenase (SLDH) level is lower than model group, no difference of science of statistics (P>0.05), and urea nitrogen levels significantly is lower than model group (P<0.05), the hepatic glycogen content utmost point is significantly higher than model group (P<0.01).Results suggest: sports drink can reduction power exhaust the rising of model mice serum urea nitrogen, lactic dehydrogenase enzyme level and the reduction of hepatic glycogen content, and the fatigue proof effect of the big more raising of dosage mouse is obvious more within the specific limits.
Experimental example four: mouse rotating stick test
4.1 test material:
4.1.1 instrument: the tired appearance of XZC-4B type mouse transfer rod formula, Shandong Academy of Medical Sciences equipment station provides.
Surplus with experimental example 1
4.2 method and result:
Get 60 of NIH mouse, male and female half and half, body weight 18-22g is divided into 5 groups at random, i.e. blank group, QINGCHUN BAO antiageing tablet positive controls, the basic, normal, high administration group of sports drink.With 2.1, continuous 7 days, the last administration was after 1 hour by each group gastric infusion, and (rotating speed 12 commentaries on classics/min) respectively organize the number of times that mouse falls from rod in the mensuration 10min, the Kruskal-Wallis method is respectively organized data difference by rotating rods method.The result sees table 3.
Table 3 crude drug is to the influence
Figure S2008100905056D00081
of mouse transfer rod drop number
Figure S2008100905056D00082
Annotate: compare * P<0.05, * * P<0.01 with the blank group.
Medicine is to the influence of mouse drop number: QINGCHUN BAO antiageing tablet, each dose groups mouse transfer rod drop number of sports drink no difference of science of statistics (P>0.05) of comparing with the blank group, but low dosage administration group mouse drop number has the trend of minimizing.
Experimental example five: the anti-anoxic experiment of mouse normal pressure
5.1 test material: with experimental example 1
5.2 method and result:
Get 60 of NIH mouse, male and female half and half, body weight 18-22g is divided into 5 groups at random, i.e. blank group, QINGCHUN BAO antiageing tablet positive controls, the basic, normal, high administration group of sports drink, 12 every group.Each organizes gastric infusion with 2.1, and continuous 7 days, the last administration was after 1 hour; With the single 200ml glass infuser that 20 gram soda limes are housed of putting into of mouse; The plug jam-pack is used at the two ends of glass infuser, and to guarantee sealing, the record anoxia in mice death time, also relatively there was indifference each treated animal death time.The result sees table 4.
Table 4 crude drug is to the influence
Figure S2008100905056D00091
of mouse normal pressure hypoxia-bearing capability
Annotate: compare * P<0.05, * * P<0.01 with the blank group.
Medicine is to the influence of the anti-anoxic of mouse: compare with the blank group, QINGCHUN BAO antiageing tablet, the continuous gastric infusion of each dosage of sports drink promptly improve mouse hypoxia-bearing capability no difference of science of statistics (P>0.05) to prolonging mouse diing time.
Experimental example six: to the influence of mouse content of hemoglobin
6.1 test material: with experimental example 1
6.2 method and result:
Get 60 of NIH mouse, male and female half and half are divided into 3 groups at random, and body weight 18-22g is divided into 5 groups at random, i.e. blank group, QINGCHUN BAO antiageing tablet positive controls, the basic, normal, high administration group of sports drink.Each organizes gastric infusion with 2.1, continuous 10d, and 1h after last is irritated stomach, each is organized mouse and plucks the eyeball blood sampling, measures every mouse content of hemoglobin and RBC number with cellanalyzer.The result sees table 5.
Table 5 crude drug is to the influence
Figure S2008100905056D00101
of mouse content of hemoglobin
Figure S2008100905056D00102
Annotate: compare * P<0.05, * * P<0.01 with the blank group.
Medicine influences mouse content of hemoglobin and RBC number purpose: behind QINGCHUN BAO antiageing tablet, the continuous gastric infusion of sports drink, the mouse content of hemoglobin compares no difference of science of statistics (P>0.05) with the blank group; High dose administration group blood plasma red blood cell number is significantly higher than blank group (P<0.01).
Content of the present invention explains detailedly through following examples, but not limit by those embodiment.
Embodiment 1: a kind of fatigue resistant sport drink, its preparation technology's method is: get the Radix Astragali 30 weight portions, Radix Angelicae Sinensis 30 weight portions, add 8 times of water gaging heating and extracting 2 times, each 1 hour, extract merged, and filtered, and filtrating is concentrated into 14 times that are equivalent to the medicinal material amount, and is subsequent use.Rhodiola root 30 weight portion medicinal materials are used steam distillation, collect the distillate that is equivalent to 3 times of medicinal material amounts, and are subsequent use; The dregs of a decoction add 8 times of water gagings and extract 2 times, and each 1 hour, extract merged, and filtered; Filtrating is concentrated into 2 times that are equivalent to the medicinal material amount, and it is 66% to containing the alcohol amount that concentrate adds ethanol, leaves standstill after fully stirring, and filters; Filtrating adds isopyknic aqueous solution that contains 1% gelatin, and fully stirs 20 minutes, filters; Filtrate recycling ethanol is concentrated into 2 times that are equivalent to the medicinal material amount, and is subsequent use.With the above-mentioned Radix Astragali, angelica extract, rhodiola root steam distillation liquid, rhodiola extract mixing, obtain magma, promptly get after adding water 1000 weight portion mixings.
Embodiment 2, a kind of fatigue resistant sport drink, and its preparation technology's method is: get the Radix Astragali 5 weight portions, Radix Angelicae Sinensis 5 weight portions, add 8 times of water gaging heating and extracting 2 times, each 1 hour, extract merged, and filtered, and filtrating is concentrated into 14 times that are equivalent to the medicinal material amount, and is subsequent use.Rhodiola root 5 weight portion medicinal materials are used steam distillation, collect the distillate that is equivalent to 3 times of medicinal material amounts, and are subsequent use; The dregs of a decoction add 8 times of water gagings and extract 2 times, and each 1 hour, extract merged, and filtered; Filtrating is concentrated into 2 times that are equivalent to the medicinal material amount, and it is 66% to containing the alcohol amount that concentrate adds ethanol, leaves standstill after fully stirring, and filters; Filtrating adds isopyknic aqueous solution that contains 1% gelatin, and fully stirs 20 minutes, filters; Filtrate recycling ethanol is concentrated into 2 times that are equivalent to the medicinal material amount, and is subsequent use.With the above-mentioned Radix Astragali, angelica extract, rhodiola root steam distillation liquid, rhodiola extract mixing; Obtain magma; Add taurine 1 weight portion; Add flavor enhancements such as an amount of sweetener, essence and acid, electrolyte and vitamins such as sodium, potassium, magnesium, calcium promptly get after adding water 400 weight portion mixings.
Embodiment 3: the prescription 1 of sports drink of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion, glucose 25 weight portions, citric acid 0.27 weight portion, sodium chloride 0.01 weight portion, potassium dihydrogen phosphate 0.01 weight portion, water 650 weight portions.
Embodiment 4: the high energy prescription 1 of sports drink of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion, HFCS 61.5 weight portions; Sodium chloride, 0.01 weight portion, stevioside 0.08 weight portion, potassium citrate 0.08 weight portion; Citric acid 0.75 weight portion, ironic citrate 0.01 weight portion, lemon oil 0.45 weight portion, potassium dihydrogen phosphate 0.04 weight portion; VitaminB10 .01 weight portion, vitamin B2 0.005 weight portion, ascorbic acid 0.1 weight portion, water 600 weight portions.
Embodiment 5: the high energy prescription 2 of sports drink of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion; Glucose 23 weight portions, magnesium carbonate 0.1 weight portion, calcium lactate 0.12 weight portion, honey 45 weight portions; Ascorbic acid 0.45 weight portion, sodium chloride 0.6 weight portion, citric acid 1 weight portion, orange essence 0.6 weight portion; Potassium chloride 0.3 weight portion, natrium citricum 0.55 weight portion, grape essence 0.6 weight portion, water 580 weight portions.
Embodiment 6: the prescription 1 that quenches the thirst fast of sports drink of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion; Glucose 30 weight portions, potassium hydroxide 0.54 weight portion, citric acid 1.5 weight portions, L-arginine 0.077 weight portion; Phytic acid 1.5 weight portions, sorbierite 2.1 weight portions, sodium chloride 0.08 weight portion; L-ascorbic acid 0.15 weight portion, caffeine 0.008 weight portion, water 650 weight portions.
Embodiment 7: the prescription 2 that quenches the thirst fast of sports drink of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion; Glucose 33 weight portions, potassium hydroxide 0.56 weight portion, citric acid 1.5 weight portions; L-arginine 0.085 weight portion, phytic acid 1.65 weight portions, magnesium chloride 0.2 weight portion; Sodium chloride 0.8 weight portion, L-ascorbic acid 0.17 weight portion, water 650 weight portions.
Embodiment 8: the prescription 3 that quenches the thirst fast of sports drink of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion; Glucose 32 weight portions, potassium hydroxide 0.35 weight portion, citric acid 3 weight portions; L-arginine-L-glutamate 0.1 weight portion, phytic acid 0.8 weight portion, essence 0.46 weight portion; NaOH 0.47 weight portion, L-ascorbic acid 0.08 weight portion, water 650 weight portions.
Embodiment 9: the prescription 4 that quenches the thirst fast of sports drink of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions; Taurine 0.3 weight portion, glucose 32 weight portions, citric acid 1.7 weight portions; L-ascorbic acid 0.08 weight portion, NaOH 1.5 weight portions, potash 0.6 weight portion; L-arginine-L-glutamate 0.08 weight portion, essence 0.48 weight portion, water 650 weight portions.
Embodiment 10: the electrolyte beverage prescription 1 of sports drink of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion; Glucose 15 weight portions, sodium chloride 2.2 weight portions, natrium citricum 1.85 weight portions, ascorbic acid 0.32 weight portion; Granulated sugar 15.3 weight portions, potassium chloride 0.67 weight portion, Sucralose 0.5 weight portion, vitamin B2 0.0077 weight portion; Citric acid 7.5 weight portions, essence 1 weight portion, potassium dihydrogen phosphate 2.8 weight portions, water 650 weight portions.
Embodiment 11: the electrolyte beverage prescription 2 of sports drink of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion; Glucose 12.3 weight portions, sodium chloride 0.27 weight portion, natrium citricum 0.46 weight portion, PN-P 0.1 weight portion; Granulated sugar 18.5 weight portions, potassium chloride 1.15 weight portions, citric acid 1.7 weight portions, magnesium sulfate 0.54 weight portion; Sodium acid phosphate 0.43 weight portion, lemon extract 0.9 weight portion, sodium dihydrogen phosphate 1.9 weight portions, water 650 weight portions.
The electrolyte beverage prescription 3 of embodiment 12. sports drinks of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion; Glucose 28 weight portions, citric acid 1.4 weight portions, saccharin sodium 0.077 weight portion; Sodium chloride 0.75 weight portion fruity flavor 0.15 weight portion, potassium dihydrogen phosphate 0.23 weight portion, sodium dihydrogen phosphate 0.3 weight portion; Ascorbic acid 0.23 weight portion, Sodium Benzoate 0.077 weight portion, water 650 weight portions.
Embodiment 13: the electrolyte beverage prescription 4 of sports drink of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion; Glucose 27 weight portions, granulated sugar 7 weight portions, sodium chloride 0.42 weight portion, citric acid 1.85 weight portions; Potassium citrate 0.23 weight portion, calcium citrate 0.7 weight portion, ascorbic acid 0.15 weight portion; Sodium Benzoate 0.08 weight portion, essence 0.15 weight portion, water 650 weight portions.
The electrolyte beverage prescription 5 of embodiment 14. sports drinks of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion; Glucose 7.7 weight portions, granulated sugar 7.7 weight portions, citric acid 2 weight portions, natrium citricum 0.6 weight portion; Saccharin sodium 0.077 weight portion, orange essence 0.6 weight portion, sodium chloride 0.85 weight portion, potassium chloride 0.38 weight portion; Ascorbic acid 0.72 weight portion, vitamin B2 0.001 weight portion, carmine 0.015 weight portion, water 670 weight portions.
The electrolyte beverage prescription 6 of embodiment 15. sports drinks of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion, glucose 12.3 weight portions; Granulated sugar 18.5 weight portions, sodium acid carbonate 1.85 weight portions, natrium citricum 0.46 weight portion, sodium acid phosphate 0.38 weight portion; Vitamin B6 0.92 weight portion, potassium chloride 1.1 weight portions, sodium chloride 0.35 weight portion, magnesium sulfate 0.54 weight portion; Citric acid 1.6 weight portions, lemon extract 0.77 weight portion, ascorbic acid 0.46 weight portion, water 650 weight portions.
Embodiment 16: the electrolyte beverage prescription 7 of sports drink of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion; Glucose 15.4 weight portions, granulated sugar 34.6 weight portions, sodium chloride 0.54 weight portion, potassium chloride 0.26 weight portion; Calcium chloride 0.35 weight portion, citric acid 0.85 weight portion, natrium citricum 0.6 weight portion, ascorbic acid 0.46 weight portion; Orange essence 0.7 weight portion, Sodium Benzoate 0.08 weight portion, water 640 weight portions.
Embodiment 17: the electrolyte beverage prescription 8 of sports drink of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion; Glucose 38.5 weight portions, saccharin sodium 0.23 weight portion, citric acid 0.23 weight portion, sodium acid carbonate 0.12 weight portion; Lemon juice 3 weight portions, potassium chloride 0.08 weight portion, sodium chloride 0.65 weight portion, sodium hydrogen phosphate 0.38 weight portion; Potassium dihydrogen phosphate 0.12 weight portion, limewash 0.15 weight portion, water 640 weight portions.
Embodiment 18: drink formula 1 in the motion way of sports drink of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion, glucose 38.5 weight portions, sodium chloride 2.7 weight portions, granulated sugar 15 weight portions, citric acid 0.8 weight portion, orange juice 77 weight portions, water 550 weight portions.
Embodiment 19: drink formula 2 in the motion way of sports drink of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion, glucose 30 weight portions, sodium chloride 2.3 weight portions, granulated sugar 23 weight portions, ascorbic acid 2.3 weight portions, sodium phosphate 4.6 weight portions, fruit juice 154 weight portions, water 400 weight portions.
Embodiment 20: drink formula 3 in the motion way of sports drink of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion, glucose 61.5 weight portions, sodium chloride 2.3 weight portions, orange juice 192 weight portions, water 400 weight portions.
Embodiment 21: drink formula 4 in the motion way of sports drink of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion, glucose 53.8 weight portions, potassium chloride 0.7 weight portion, sodium chloride 2.3 weight portions, citric acid 0.7 weight portion ascorbic acid 2.3 weight portions, water 650 weight portions.
Embodiment 22: drink formula 5 in the motion way of sports drink of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion; Granulated sugar 7.7 weight portions, citric acid 0.6 weight portion, compound sugar 23 weight portions; Potassium dihydrogen phosphate 0.08 weight portion, potassium chloride 0.08 weight portion, sodium dihydrogen phosphate 0.08 weight portion; Sodium chloride 0.6 weight portion, lemon extract 0.77 weight portion, water 660 weight portions.
Embodiment 23: drink formula 6 in the motion way of sports drink of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion; Glucose 54 weight portions, citric acid 2.5 weight portions, granulated sugar 11.5 weight portions; Sodium chloride 1.23 weight portions, potassium dihydrogen phosphate 0.37 weight portion, ascorbic acid 0.38 weight portion; Sodium dihydrogen phosphate 0.43 weight portion, essence 0.15 weight portion, water 630 weight portions.
Embodiment 24: the raising muscle function prescription of sports drink of the present invention
The Radix Astragali 5 weight portions, Radix Angelicae Sinensis 1 weight portion, rhodiola root 3 weight portions, taurine 0.3 weight portion, leucine 2.3 weight portions, granulated sugar 15.4 weight portions, isoleucine 2.3 weight portions, fructose 15.4 weight portions, proline 1.5 weight portions, water 660 weight portions.

Claims (2)

1. the preparation method of a fatigue resistant sport drink, its preparation technology's method is: get the Radix Astragali 30 weight portions, Radix Angelicae Sinensis 30 weight portions, add 8 times of water gaging heating and extracting 2 times; Each 1 hour, extract merged, and filtered; Filtrating is concentrated into 14 times that are equivalent to the medicinal material amount, and is subsequent use; Rhodiola root 30 weight portion medicinal materials are used steam distillation, collect the distillate that is equivalent to 3 times of medicinal material amounts, and are subsequent use; The dregs of a decoction add 8 times of water gagings and extract 2 times, and each 1 hour, extract merged, and filtered; Filtrating is concentrated into 2 times that are equivalent to the medicinal material amount, and it is 66% to containing the alcohol amount that concentrate adds ethanol, leaves standstill after fully stirring, and filters; Filtrating adds isopyknic aqueous solution that contains 1% gelatin, and fully stirs 20 minutes, filters; Filtrate recycling ethanol is concentrated into 2 times that are equivalent to the medicinal material amount, and is subsequent use; With the above-mentioned Radix Astragali, angelica extract, rhodiola root steam distillation liquid, rhodiola extract mixing, obtain magma, promptly get after adding water 1000 weight portion mixings.
2. the preparation method of a kind of fatigue resistant sport drink according to claim 1; It is characterized in that: the Radix Astragali and Radix Angelicae Sinensis are fried in shallow oil extract, rhodiola root steam distillation liquid, rhodiola extract mixing altogether; Add taurine, add the water mixing behind adding flavor enhancement, electrolyte, vitamin and the amino acid.
CN2008100905056A 2008-03-25 2008-03-25 Fatigue resistant sport drink and method of preparing the same Expired - Fee Related CN101248880B (en)

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CN103054934A (en) * 2012-12-26 2013-04-24 李发 Rhodiola traditional Chinese medicine life-lengthening pill and preparation method thereof
CN103750143B (en) * 2014-01-21 2015-08-12 中国人民解放军第三军医大学 Resist oxygen lack type antifatigue energy composition and application thereof
CN105767329A (en) * 2016-04-13 2016-07-20 严绍章 Anti-fatigue functional beverage and preparing method thereof
CN105942060A (en) * 2016-05-16 2016-09-21 安庆市江岸品香食品有限责任公司 Anti-fatigue functional drink and preparation method thereof
CN105995354A (en) * 2016-06-23 2016-10-12 甘肃赫博陇药科技有限责任公司 Functional astragaluspolysaccharide drink with functions of immunity enhancement and fatigue resistance and preparation technology of functional astragalus polysaccharide drink
CN106721779A (en) * 2016-11-15 2017-05-31 昆山国元生物科技有限公司 Taurine sports drink containing soybean peptide
CN108991307A (en) * 2018-06-08 2018-12-14 山西大学 A kind of Radix Astragali compound fatigue-resistant beverage and preparation method thereof
CN115777826A (en) * 2022-11-14 2023-03-14 上海市杨浦区青少年科技站 An antifatigue chewing gum containing radix Angelicae sinensis and radix astragali extract

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CN1813868A (en) * 2005-12-23 2006-08-09 张晶 Composition for treating and improving chronic fatigue syndrome and its preparing method
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