CN102258715A - Honeysuckle wine - Google Patents

Honeysuckle wine Download PDF

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Publication number
CN102258715A
CN102258715A CN2011101946695A CN201110194669A CN102258715A CN 102258715 A CN102258715 A CN 102258715A CN 2011101946695 A CN2011101946695 A CN 2011101946695A CN 201110194669 A CN201110194669 A CN 201110194669A CN 102258715 A CN102258715 A CN 102258715A
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filtrate
honeysuckle
wine
semen coicis
honeysuckle wine
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范成连
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Abstract

The invention relates to health-care honeysuckle wine, which is prepared from white liquor, honeysuckle, medlar, liquoric root, coix seed and red date according to a certain ratio and by boiling, soaking, fermenting, distilling and filtering. Based on a principle of promotion and restriction of traditional Chinese medicine, the medicinal materials are effectively combined to produce a synergetic effect; these medicinal materials are soaked in white liquor to play effect under the action of the nature of the white liquor; and thus, the health-care honeysuckle wine has the health-care effects of stimulating appetite, tonifying the spleen, nourishing heart, liver, spleen and kidney, clearing heat, detoxifying, replenishing vital essence, improving eyesight, delaying aging, improving immunity and the like. Meanwhile, the preparation process is simple, the cost is low, and thus, the honeysuckle wine is easy to promote.

Description

Honeysuckle wine
Technical field
The present invention relates to a kind of honeysuckle wine, belong to the field of Chinese medicines with health care.
Background technology
Wine was continuous thousands of years at Chinese the earth as a kind of culture, and ancients also have saying of the health preserving of drinking.Just be loaded with " wine brewed in spring, with Jie's eyebrow longevity " for this reason, the verse of " claim that female rhinoceros an ancient wine vessel made of horn, all things is boundless " in " Book of Songs Bin wind ".Mean with wine to help length good, act an ancient wine vessel made of horn is toasted and is wished longevity, all fills a wine cup for and long-lived the contact together.Wine a great variety in the market is with grain or alcohol concocted Chinese liquor mostly, though have certain health preserving effect, effect is not good enough.Health care effect wine on the market is many to form with medical material infusions such as Radix Ginseng, Cornu Cervi Pantotrichums, expensive and the kind effect is single.And the raising of living standards of the people to the cognition raising of health idea, impels the rush of demand of health care wine.Given this, the applicant sums up for many years Chinese medicine conditioning experience, and the research Chinese herbal medicine is to improving the characteristic of immunity, excavates Chinese medicine and transfers and mend double executing and the marrow of determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, has invented a kind of honeysuckle wine of health-care effect.
Summary of the invention
Purpose of the present invention just provides a kind of honeysuckle wine that has heat-clearing and toxic substances removing, nourishing the liver and kidney, replenishing vital essence to improve eyesight and improve health-care effects such as immunity.
Honeysuckle wine of the present invention, it is to be made by following scheme by Chinese liquor, Flos Lonicerae, Fructus Lycii, Radix Glycyrrhizae, Semen Coicis, Fructus Jujubae:
(1) medicine each component consumption of the present invention is:
Flos Lonicerae 40~60, Fructus Lycii 20~35, Radix Glycyrrhizae 4~12, Semen Coicis 10~25, Fructus Jujubae 10~25.
(2) with said medicine with radioactive element cobalt irradiation sterilization, it is stand-by to clean the roguing crushed after being dried respectively, except the Semen Coicis;
(3) the Semen Coicis roguing is ground into the end, crosses 20~40 mesh sieves, place 50~70 parts of 50~65 ° of high quality liquors to soak 25~50 days under the room temperature after, cross 80~120 order screens, filtrate is stored standby;
(4) go on foot described medicated powder Flos Lonicerae, Fructus Lycii, Radix Glycyrrhizae, Semen Coicis, Fructus Jujubae medicated powder with second, add 150~300 parts of water, 60~70 ℃ of maintenance 50~80min in cooker well by above-mentioned weight portion proportioning, reheat boils, 90~100 ℃ keep 10~30min, cease fire, temperature is filtered with 80~120 order screens in the time of 50 ℃, returns cool rear filtrate and stores; Filtering residue is after second extraction, and filtrate is fully mixed with extracting solution for the first time, stores standbyly, and filtering residue is discarded;
(5) (3) and (4) are made filtrate by 1: 1 mixed liquor, mixed liquor mixes with 50~65 ° of Chinese liquor (number of degrees of allotment are selected the suitable ratio of blending as required), insert storage tank, be sealed in fermented in the cellar 30~45 days after, distilled 100~140 order screens at boiler, get final product described honeysuckle wine;
Honeysuckle wine of the present invention, wherein the Flos Lonicerae sweet in the mouth is cold in nature, attaches to the lung and stomach meridians, and heat-clearing and toxic substances removing is arranged, and eliminating carbuncle looses swollen, eliminating pathogenic heat from blood to cure dysentery, clothes are prolonged life for a long time, have antibiotic, antiviral, raise immunity, antiinflammatory, refrigeration function.Antibacterial, virus, inflammation there is the obvious suppression effect.Can promote lymphocyte transformation, strengthen leukocytic phagocytic function, reduce cholesterol level in the blood plasma, and can obviously reduce vivotoxin content.The Fructus Lycii sweet in the mouth, property is flat, returns Liver Channel, kidney channel, lung meridian, treatment hepatic and renal YIN deficiency, soreness of the waist and knees, dizziness, forgetful, dizzy, many tears of blurred vision are arranged, quenches one's thirst, disease such as seminal emission.And the scalable body's immunity, can effectively suppress tumor growth and cell mutation, have slow down aging, anti-fatty liver, blood lipid regulation and blood glucose, the effect of aspect such as promotion hemopoietic function.Radix Glycyrrhizae property is flat, and sweet in the mouth is returned 12 warps, invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.Semen Coicis slightly sweet flavor, cold nature, nontoxic are gone into spleen, stomach, lung, large intestine channel, have that inducing diuresis to remove edema, spleen invigorating are dried, arthralgia relieving by relaxing muscles and tendons, clearing away heat and discharging pus face nourishing antidebilitation are waited for a long time effect.The Fructus Jujubae sweet in the mouth is warm in nature, returns spleen, stomach warp, contains protein, fat, sugar, calcium, phosphorus, ferrum, magnesium and abundant vitamin A, vitamin C, vitamin B1, vitamin B2, carotene etc. have the spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid, the lung moistening spleen invigorating transfers battalion to defend, and separates the effect of poison of drug; The principle that counteracts each other according to Chinese medicine, make each efficacy of drugs produce synergism the effective combination of these medicines, with soaking in Chinese liquor, borrow the property of wine, the performance drug effect, thereby reach appetite promoting and the spleen strengthening, the nourishing heart, liver,spleen,kidney, health-care effecies such as heat-clearing and toxic substances removing, replenishing vital essence to improve eyesight, slow down aging and raising immunity.Processing technology of the present invention is simple, with low cost simultaneously, is beneficial to popularization.
The specific embodiment
Embodiment one
Honeysuckle wine of the present invention, it is to be made by following scheme by Chinese liquor Flos Lonicerae, Fructus Lycii, Radix Glycyrrhizae, Semen Coicis, Fructus Jujubae:
(1) medicine each component consumption of the present invention is:
Flos Lonicerae 40, Fructus Lycii 20, Radix Glycyrrhizae 4, Semen Coicis 10, Fructus Jujubae 10.
(4) with said medicine with radioactive element cobalt irradiation sterilization, it is stand-by to clean the roguing crushed after being dried respectively, except the Semen Coicis;
(5) the Semen Coicis roguing is ground into the end, crosses 20~40 mesh sieves, place 50 parts of 50 ° of high quality liquors to soak after 25 days under the room temperature, cross 80~120 order screens, filtrate is stored standby;
(4) go on foot described medicated powder Flos Lonicerae, Fructus Lycii, Radix Glycyrrhizae, Semen Coicis, Fructus Jujubae medicated powder with second, add 150 parts of water, 60 ℃ of maintenance 50min in cooker well by above-mentioned weight portion proportioning, reheat boils, 90 ℃ keep 10min, cease fire, temperature is filtered with 80~120 order screens in the time of 50 ℃, returns cool rear filtrate and stores; Filtering residue is after second extraction, and filtrate is fully mixed with extracting solution for the first time, stores standbyly, and filtering residue is discarded;
(5) (3) and (4) are made filtrate by 1: 1 mixed liquor, mixed liquor and 50 ° of Chinese liquor (number of degrees of allotment are selected the suitable ratio of blending as required) mix, insert storage tank, be sealed in fermented 30 days in the cellar after, distilled 100~140 order screens at boiler, get final product institute's honeysuckle wine;
Embodiment two
(1) medicine each component consumption of the present invention is:
Flos Lonicerae 50, Fructus Lycii 27, Radix Glycyrrhizae 8, Semen Coicis 27, Fructus Jujubae 28.
(6) with said medicine with radioactive element cobalt irradiation sterilization, it is stand-by to clean the roguing crushed after being dried respectively, except the Semen Coicis;
(7) the Semen Coicis roguing is ground into the end, crosses 20~40 mesh sieves, place 60 parts of 60 ° of high quality liquors to soak after 40 days under the room temperature, cross 80~120 order screens, filtrate is stored standby;
(4) go on foot described medicated powder Flos Lonicerae, Fructus Lycii, Radix Glycyrrhizae, Semen Coicis, Fructus Jujubae medicated powder with second, add 200 parts of water, 65 ℃ of maintenance 70min in cooker well by above-mentioned weight portion proportioning, reheat boils, 95 ℃ keep 20min, cease fire, temperature is filtered with 80~120 order screens in the time of 50 ℃, returns cool rear filtrate and stores; Filtering residue is after second extraction, and filtrate is fully mixed with extracting solution for the first time, stores standbyly, and filtering residue is discarded;
(5) (3) and (4) are made filtrate by 1: 1 mixed liquor, mixed liquor and 60 ° of Chinese liquor (number of degrees of allotment are selected the suitable ratio of blending as required) mix, insert storage tank, be sealed in fermented 40 days in the cellar after, distilled 100~140 order screens at boiler, get final product institute's honeysuckle wine;
Embodiment three
(1) medicine each component consumption of the present invention is:
Flos Lonicerae 60, Fructus Lycii 35, Radix Glycyrrhizae 12, Semen Coicis 25, Fructus Jujubae 25.
(8) with said medicine with radioactive element cobalt irradiation sterilization, it is stand-by to clean the roguing crushed after being dried respectively, except the Semen Coicis;
(9) the Semen Coicis roguing is ground into the end, crosses 20~40 mesh sieves, place 70 parts of 65 ° of high quality liquors to soak after 50 days under the room temperature, cross 80~120 order screens, filtrate is stored standby;
(4) go on foot described medicated powder Flos Lonicerae, Fructus Lycii, Radix Glycyrrhizae, Semen Coicis, Fructus Jujubae medicated powder with second, add 300 parts of water, 70 ℃ of maintenance 80min in cooker well by above-mentioned weight portion proportioning, reheat boils, 100 ℃ keep 30min, cease fire, temperature is filtered with 80~120 order screens in the time of 50 ℃, returns cool rear filtrate and stores; Filtering residue is after second extraction, and filtrate is fully mixed with extracting solution for the first time, stores standbyly, and filtering residue is discarded;
(5) (3) and (4) are made filtrate by 1: 1 mixed liquor, mixed liquor and 65 ° of Chinese liquor (number of degrees of allotment are selected the suitable ratio of blending as required) mix, insert storage tank, be sealed in fermented 45 days in the cellar after, distilled 100~140 order screens at boiler, get final product institute's honeysuckle wine;
Clinical trial
In order to verify the good effect of honeysuckle wine of the present invention, the inventor has carried out a large amount of animals and clinical experiment, and existing selection portion separating tests is reported as follows.
Test example 1 honeysuckle wine of the present invention is to the influence of Rats Organs and Tissues coefficient
One, physical data
1, laboratory animal source: buy 120 of SD rats from Zhengzhou University's medical college Experimental Animal Center, body weight 60~80g is divided into four groups at random, and 30 every group, male and female half and half, single cage is raised.
Two, test method
Animal subject is established three dosage groups (2.5ml/kg body weight, 5ml/kg body weight, 10ml/kg body weight) and a matched group (distilled water filling stomach), irritates stomach, continuous 30 days for respectively each dosage group animal subject honeysuckle wine.The equal feed normal feedstuff of each treated animal of duration of test, and ad lib, drinking-water.Experiment finishes the back and puts to death rat, and liver,kidney,spleen etc. is carried out histopathologic examination's (paraffin section).
Three, result of the test
The dirty body ratio of each treated animal of table 1 result (%)
Figure BSA00000536190500051
As can be seen from Table 1, all animal liver,kidney,spleens etc. there is no obvious pathological change, illustrate honeysuckle wine to have no side effect, safe and reliable.
Test example 2 honeysuckle wines of the present invention are to immunoregulatory effect
One, physical data
1, laboratory animal source: buy 88 of the female Kunming mouses of cleaning level from Zhengzhou University's medical college Experimental Animal Center, body weight 18~22g is divided into 8 groups at random, and 11 every group, single cage is raised.
Two, dosage is selected
Honeysuckle wine human body recommended amounts is 60ml/ days/people (concentrated solution is 6ml/ days/people) for the human body recommended amounts, the dose,equivalent of mice is equivalent to 10 times of human body recommended amounts, be that to take the 1ml/kg body weight every day be low dosage, respectively establish a dosage group by low 2 times and 3 times of measuring again, i.e. 2ml/ days/kg body weight (middle dosage) and 3ml/ days/kg body weight (high dose).Matched group is given distilled water, and equal-volume is irritated stomach and tried mice after 30 days continuously, measures every index.
Three, experimental apparatus and reagent
Slide gauge (precision 0.02mm), sheep red blood cell (SRBC) (SRBC), microsyringe (50ul).
CO2 gas incubator, water bath with thermostatic control, centrifuge, operating theater instruments, slide frame, 200 eye mesh screens, guinea pig serum (complement), Hanks liquid, SA buffer, agarose.
756MC ultraviolet-uisible spectrophotometer, timer, hematochrome suction pipe, india ink, sodium carbonate.
Four, test method:
1. internal organs/weight ratio pH-value determination pH:
2. delayed allergy (DTH) (the sufficient sole of the foot thickens method)
After mouse peritoneal injection 2% (v/v) SRBC0.2ml sensitization 4 days, measure left back sufficient sole of the foot thickness, then measuring point subcutaneous injection 20% (v/v) SRBC (the every Mus of 20ul/), left back sufficient sole of the foot portion thickness was measured in injection back in 24 hours, same position is measured three times, averages.The degree of representing DTH with the difference (swelling degree of the paw) of sufficient sole of the foot thickness before and after attacking.
3. the spleen antibody-producting cell detects (Jerne improves slide method)
Get Sanguis caprae seu ovis, with normal saline washing three times, every Mus is through lumbar injection 2% (v/v) SRBC0.2ml.The mice of SRBC immunity after 5 days put to death, get spleen, make cell suspension.After the culture medium heating for dissolving of top layer, mix with the double HanKs liquid of equivalent, the packing small test tube, every pipe 0.5ml, in pipe, add 50ul10%SRBC (v/v again, with SA liquid preparation), the 10ul splenocyte suspension, rapidly behind the mixing, be poured on the slide of brushing the agarose thin layer, treat that agar solidifies after, the slide level buckled be placed on the horse, put into the CO2 gas incubator incubation 1.5 hours, put in the slide frame groove with the complement (1: 10) of SA buffer dilution then, continue incubation after 1.5 hours, counting hemolysis plaque number.
4. mice carbon clearance test
The india ink of mouse tail vein injection dilution in 1: 3 treats that prepared Chinese ink injects timing immediately.After injecting prepared Chinese ink, 1,10min, get blood 20ul from the angular vein clump respectively, and it is added to 2mlNa 2CO 3In the solution.With the 756MC ultraviolet-uisible spectrophotometer at 600nm wavelength place's photometry density value (OD), with Na 2CO 3Solution is made blank.Mice is put to death, get liver and spleen is weighed.Calculate phagocytic index a.
5. experimental data is added up with the t check.
Five, result of the test
1. honeysuckle wine is to the influence of mice body weight
Table 2 is respectively organized the initial body weight of mice
Figure BSA00000536190500071
Table 3 is respectively organized the end body weight of mice
Figure BSA00000536190500072
Table 2~3 results show that per os gave the honeysuckle wine of mice doses after 30 days, and its body weight and matched group be there was no significant difference (immune two groups middle and high dosage treated animal respectively has in the unexpected death in mid-term) relatively.
2. honeysuckle wine is to the influence (seeing Table 4) of mice internal organs/body weight ratio
Table 4 honeysuckle wine is to the influence of mice internal organs/body weight ratio
Figure BSA00000536190500081
By table 4 as seen, per os gives the honeysuckle wine 30 days of mice various dose, the organ coefficient of each treated animal and matched group relatively there are no significant difference.
3. honeysuckle wine is to the influence of mice delayed allergy (DTH)
Table 5 honeysuckle wine is to the influence of mice delayed allergy (DTH)
Figure BSA00000536190500082
By table 5 as seen, per os gives the honeysuckle wine 30 days of mice various dose, and the swelling degree of the paw of middle dosage group and matched group relatively have significant difference (P<0.05).
4. honeysuckle wine is to the influence of mouse spleen antibody-producting cell number
Table 6 honeysuckle wine is to the influence of mouse spleen antibody-producting cell number
By table 6 as seen, per os gives the honeysuckle wine 30 days of mice various dose, wherein, the antibody-producting cell number and the matched group of high dose group relatively have significant difference.
5. honeysuckle wine is to the influence of mouse monokaryon-macrophage carbon clearance function
Table 7 honeysuckle wine is to the influence of mouse monokaryon-macrophage carbon clearance function
Figure BSA00000536190500091
By table 7 as seen, per os gives the honeysuckle wine 30 days of mice various dose, and the monokaryon of its high dose group-macrophage phagocytic index and matched group relatively have significant difference.
Six, brief summary
Per os gives the honeysuckle wine 30 days of mice various dose, can obviously improve spleen antibody-producting cell number, mice swelling degree of the paw and the monokaryon-macrophage phagocytic function of mice.According to the regulation of " the health food function assessment assessment process and the method for inspection ", the decidable honeysuckle wine has immunoregulation effect.
The 3 honeysuckle wine health-care effect clinical experiments of test example
One, physical data
1. the experiment crowd originates: recruit 100 routine healthy male alcohol users, do not have long-term history of drinking history, 26~58 years old age.
2. dosage: the quantity of drinking is 200~300ml, and the ethanol number of degrees are 46~52 °.
Two, experimental technique:
Earlier the drink common white spirit is drunk honeysuckle wine again after 1 month, continues drink honeysuckle wine January, and the back 48h that drinks compares according to inspect by instrument results such as clinical symptoms and electrocardiogram, X line, laboratory, esophagoscope, electronic gastroscope, colonoscopes with interior.
Three, diagnostic criteria
The complication such as the caused arrhythmia in back, acute corrosive esophagitis, acute corrosive gastritis, acute gastroenteritis of drinking all meet the diagnostic criteria of " clinical disease diagnosis is according to curing the improvement standard ".
The clinical experiment of table 8 honeysuckle wine health-care effect
Annotate: compare P<0.05 with matched group
By table 8 as seen, through drinking honeysuckle wine 30 days, it and common white spirit are far different, significant difference is relatively arranged not only to not infringement of human body, and the drink back have good protecting function to internal organs such as heart, esophagus, gastrointestinal, livers.
Conclusion
Show through animal and clinical test results; this kind honeysuckle wine has significant curative effect to the protection heart, liver,spleen,kidney, esophagus, gastrointestinal, slow down aging and raising immunity etc.; taking convenience, and in the test testing process, do not find obvious adverse reaction and toxic and side effects.

Claims (3)

1. honeysuckle wine, it is characterized in that it is to be made by following scheme by Chinese liquor, Flos Lonicerae, Fructus Lycii, Radix Glycyrrhizae, Semen Coicis, Fructus Jujubae: medicine each component consumption of the present invention is: Flos Lonicerae 40~60, Fructus Lycii 20~35, Radix Glycyrrhizae 4~12, Semen Coicis 10~25, Fructus Jujubae 10~25.
2. honeysuckle wine according to claim 1, its preparation scheme is as follows:
A) take by weighing Flos Lonicerae, Fructus Lycii, Radix Glycyrrhizae, Semen Coicis, Fructus Jujubae with the sterilization of radioactive element cobalt irradiation by each component, it is stand-by to clean the roguing crushed after being dried respectively, except the Semen Coicis;
B) the Semen Coicis roguing is ground into the end, crosses 20~40 mesh sieves, place 50~70 parts of 50~65 ° of high quality liquors to soak 25~50 days under the room temperature after, cross 80~120 order screens, filtrate 1 is stored standby;
C) with medicated powder Flos Lonicerae, Fructus Lycii, Radix Glycyrrhizae, Semen Coicis, the Fructus Jujubae medicated powder of described weight proportion, add 150~300 parts of water, 60~70 ℃ of maintenance 50~80min in cooker, reheat boils, 90~100 ℃ keep 10~30min, cease fire, temperature is filtered with 80~120 order screens in the time of 50 ℃, returns cool rear filtrate and stores; Filtering residue is after second extraction, and filtrate is fully mixed with extracting solution for the first time, filtrate 2, stores standbyly, filtering residue is discarded;
D) by fully mixing filtrate 1, filtrate 2 at 1: 1, promptly getting honeysuckle wine main component filtrate 3;
E) filtrate 3 and 50~65 ° of Chinese liquor (number of degrees of allotment are selected the suitable ratio of blending as required) are mixed, insert storage tank, be sealed in fermented in the cellar 30~45 days after, distilled 100~140 order screens at boiler, get final product described honeysuckle wine.
3. according to claim 1 and 2 described honeysuckle wines, drink 60ml/ people and be advisable every day.
CN2011101946695A 2011-07-13 2011-07-13 Honeysuckle wine Pending CN102258715A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103571727A (en) * 2013-11-28 2014-02-12 覃祖仁 Honeysuckle wine and preparation method thereof
CN103740554A (en) * 2013-12-13 2014-04-23 闭美娥 Honeysuckle flower wine
CN104232409A (en) * 2014-09-25 2014-12-24 眉山市黄牛泥窖酒业有限公司 White spirit and brewing method thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1110312A (en) * 1994-12-06 1995-10-18 吴栋材 Honeysuckle wine
CN1156004A (en) * 1995-12-09 1997-08-06 史雄飞 Drink and producing method
CN1544603A (en) * 2003-11-12 2004-11-10 张路明 Honeysuckle wine making method
CN1563331A (en) * 2004-03-22 2005-01-12 卜国钦 Homeysuckle flower wine
CN101153256A (en) * 2007-09-28 2008-04-02 范成连 Honeysuckle wine

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1110312A (en) * 1994-12-06 1995-10-18 吴栋材 Honeysuckle wine
CN1156004A (en) * 1995-12-09 1997-08-06 史雄飞 Drink and producing method
CN1544603A (en) * 2003-11-12 2004-11-10 张路明 Honeysuckle wine making method
CN1563331A (en) * 2004-03-22 2005-01-12 卜国钦 Homeysuckle flower wine
CN101153256A (en) * 2007-09-28 2008-04-02 范成连 Honeysuckle wine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
赵洪静等: "中国保健(功能)饮料分析", 《中国食品学报》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103571727A (en) * 2013-11-28 2014-02-12 覃祖仁 Honeysuckle wine and preparation method thereof
CN103740554A (en) * 2013-12-13 2014-04-23 闭美娥 Honeysuckle flower wine
CN104232409A (en) * 2014-09-25 2014-12-24 眉山市黄牛泥窖酒业有限公司 White spirit and brewing method thereof

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Application publication date: 20111130