CN101199719A - 强肾颗粒生产工艺 - Google Patents
强肾颗粒生产工艺 Download PDFInfo
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Abstract
本发明涉及一种中药制剂，具体涉及一种以中草药为原料，治疗肾虚水肿、腰痛、遗精、阳痿、早泄等症。亦可用于属于肾虚症的慢性肾炎和久治不愈的肾盂肾炎。本发明的特征在于它是由下述组分的中草药组成的配方：鹿茸20.8g，山药208.3g，山茱萸104.2g，熟地黄208.3g，枸杞子104.2g，丹参208.3g，补骨脂104.2g，牡丹皮104.2g，桑椹104.2g，益母草208.3g，茯苓208.3g，泽泻104.2g，杜仲(炙)104.2g，人参茎叶总皂苷6.3g。
Description
技术领域：
本发明涉及一种中药制剂，具体涉及一种以中草药为原料，治疗肾虚水肿、腰痛、遗精、阳痿、早泄等症。亦可用于属于肾虚症的慢性肾炎和久治不愈的肾盂肾炎。
发明内容：
本发明的技术问题是通过下面的技术方案解决的。其特征在于它是由下述组分的中草药组成的配方：鹿茸20.8g山药208.3g 山茱萸104.2g熟地黄208.3g枸杞子104.2g丹参208.3g补骨脂104.2g 牡丹皮104.2g桑椹104.2g益母草208.3g茯苓208.3g泽泻104.2g杜仲(炙)104.2g人参茎叶总皂苷6.3g。
鹿茸：甘、咸，温。归肾、肝经。壮肾阳，益精血，强筋骨，调冲任，托疮毒。用于阳痿滑精，宫冷不孕，羸瘦，神疲，畏寒，眩晕耳鸣耳聋，腰脊冷痛，筋骨痿软，崩漏带下，阴疽不敛。
山药：甘，平。归脾、肺、肾经。补脾养胃，生津益肺，补肾涩精。用于脾虚食少，久泻不止，肺虚喘咳，肾虚遗精，带下，尿频，虚热消渴。麸炒山药补脾健胃。用于脾虚食少，泄泻便溏，白带过多。
山茱萸：酸、涩，微温。归肝、肾经。补益肝肾，涩精固脱。用于眩晕耳鸣，腰膝酸痛，阳痿遗精，遗尿尿频，崩漏带下，大汗虚脱。内热消渴。
熟地黄：甘，微温。归肝、肾经。滋阴补血，益精填髓。用于肝肾阴虚，腰膝酸软，骨蒸潮热，盗汗遗精，内热消渴，血虚萎黄，心悸怔忡，月经不调，崩漏下血，眩晕，耳鸣，须发早白。
枸杞子：甘，平。归肝、肾经。滋补肝肾，益精明目。用于虚劳精亏，腰膝酸痛，眩晕耳鸣，内热消渴，血虚萎黄，目昏不明。
丹参：苦，微寒。归心、肝经。祛瘀止痛，活血通经，清心除烦。用于月经不调，经闭痛经，癥瘕积聚，胸腹刺痛，热痹疼痛，疮疡肿痛，心烦不眠；肝脾肿大，心绞痛。
补骨脂：辛、苦、温。归肾、脾经。温肾助阳，纳气，止泻。用于阳萎遗精，遗尿尿频，腰膝冷痛，肾虚作喘，五更泄泻；外用治白癜风，斑秃。
牡丹皮：苦、辛，微寒。归心、肝、肾经。清热凉血，活血化瘀。用于温毒发斑，吐血衄血，夜热早凉，无汗骨蒸，经闭痛经，痈肿疮毒，跌扑伤痛。
桑椹：归心、肝、肾经。补血滋阴，生津润燥。用于眩晕耳鸣，心悸失眠，须发早白，津伤口渴，内热消渴，血虚便秘。
益母草：肝、心包经。活血调经，利尿消肿。用于月经不调，痛经，经闭，恶露不尽，水肿尿少；急性肾炎水肿。
茯苓：平。归心、肺、脾、肾经。利水渗湿，健脾宁心。用于水肿尿少，痰饮眩悸，脾虚食少，便溏泄泻，心神不安，惊悸失眠。
泽泻：归肾，膀胱经。利小便，清湿热。用于小便不利，水肿胀满，泄泻尿少，痰饮眩晕，热淋涩痛；高血脂。
杜仲：归肝、肾经。补肝肾，强筋骨，安胎。用于肾虚腰痛，筋骨无力，妊娠漏血，胎动不安和高血压症。
以上十四味，除人参茎叶总皂苷外，将鹿茸、牡丹皮及山药104.2g，干燥，粉碎成细粉备用。取丹参粉碎成粗粉，照流浸膏剂与浸膏剂项下的渗漉法，用75％乙醇浸渍后进行渗漉，收集漉液回收乙醇，减压浓缩至稠膏状。剩下的山药及其余9味，加水煎煮二次，第一次加水10倍量，浸泡30分钟，煎煮2小时，滤过，第二次加水8倍量，煎煮1.5小时，过滤，合并滤液，浓缩至相对密度为1.30(40℃)，加入乙醇使含醇量达70％，静置12小时(必要时冷藏)。取上清液备用，将沉淀物再用70％乙醇洗涤，将洗液与上清液合并，回收乙醇减压浓缩至相对密度为1.30(40℃)的稠膏。将以上两种稠膏与人参茎叶总皂苷、鹿茸等细粉混匀，在60-70℃干燥，干膏粉碎，过筛(4-5号)，用75％-80％乙醇制软材，制成颗粒，于60-70℃干燥，制成1000g，即得。。
Claims (2)
1.强肾颗粒，其特征在于它是由下述组分的中药材组成的配方：
鹿茸20.8g 山药208.3g 山茱萸104.2g 熟地黄208.3g 枸杞子104.2g丹参208.3g 补骨脂104.2g 牡丹皮104.2g 桑椹104.2g 益母草208.3g茯苓208.3g 泽泻104.2g 杜仲(炙)104.2g 人参茎叶总皂苷6.3g。
2.强肾颗粒制备方法，其特征在于它包括下述步骤：
(1).鹿茸、牡丹皮及山药104.2g，干燥，粉碎成细粉备用。
(2).取丹参粉碎成粗粉，照流浸膏剂与浸膏剂项下的渗漉法，用75％乙醇浸渍后进行渗漉，收集漉液回收乙醇，减压浓缩至稠膏状。
(3).剩下的山药及其余9味(除人参茎叶总皂苷)，加水煎煮二次，第一次加水10倍量，浸泡30分钟，煎煮2小时，滤过，第二次加水8倍量，煎煮1.5小时，过滤，合并滤液，浓缩至相对密度为1.30(40℃)，加入乙醇使含醇量达70％，静置12小时(必要时冷藏)。
(4).取上清液备用，将沉淀物再用70％7醇洗涤，将洗液与上清液合并，回收乙醇减压浓缩至相对密度为1.30(40℃)的稠膏。
(5).将以上两种稠膏与人参茎叶总皂苷、鹿茸等细粉混匀，在60-70℃干燥，干膏粉碎，过筛(4-5号)，用75％-80％乙醇制软材，制成颗粒，于60-70℃干燥，制成1000g，即得。
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101912541A (zh) * | 2010-09-02 | 2010-12-15 | 冯学安 | 用于治疗阳痿、早泄的中药胶囊 |
| CN103191260A (zh) * | 2013-04-08 | 2013-07-10 | 高蓉 | 通过补肾壮阳治疗阳痿早泄的中药制剂 |
| CN103211952A (zh) * | 2013-05-20 | 2013-07-24 | 广州市云桥生物科技有限公司 | 一种用于治疗水肿的中药组合物 |
| CN106039098A (zh) * | 2016-08-18 | 2016-10-26 | 赵志坚 | 一种治疗肾虚腰痛的中药及其制备方法 |
| CN113116999A (zh) * | 2019-12-30 | 2021-07-16 | 辽宁上药好护士药业（集团）有限公司 | 一种鲜鹿茸制备强肾片的方法 |
-
2006
- 2006-12-14 CN CNA2006101347594A patent/CN101199719A/zh active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101912541A (zh) * | 2010-09-02 | 2010-12-15 | 冯学安 | 用于治疗阳痿、早泄的中药胶囊 |
| CN103191260A (zh) * | 2013-04-08 | 2013-07-10 | 高蓉 | 通过补肾壮阳治疗阳痿早泄的中药制剂 |
| CN103191260B (zh) * | 2013-04-08 | 2014-04-16 | 高蓉 | 通过补肾壮阳治疗阳痿早泄的中药制剂 |
| CN103211952A (zh) * | 2013-05-20 | 2013-07-24 | 广州市云桥生物科技有限公司 | 一种用于治疗水肿的中药组合物 |
| CN106039098A (zh) * | 2016-08-18 | 2016-10-26 | 赵志坚 | 一种治疗肾虚腰痛的中药及其制备方法 |
| CN113116999A (zh) * | 2019-12-30 | 2021-07-16 | 辽宁上药好护士药业（集团）有限公司 | 一种鲜鹿茸制备强肾片的方法 |
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