CN101180287B - 通过还原消除相应的4-卤素衍生物而制备2,5-取代的四氢吡喃衍生物的方法 - Google Patents

通过还原消除相应的4-卤素衍生物而制备2,5-取代的四氢吡喃衍生物的方法 Download PDF

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Publication number
CN101180287B
CN101180287B CN2006800179689A CN200680017968A CN101180287B CN 101180287 B CN101180287 B CN 101180287B CN 2006800179689 A CN2006800179689 A CN 2006800179689A CN 200680017968 A CN200680017968 A CN 200680017968A CN 101180287 B CN101180287 B CN 101180287B
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represent
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CN101180287A (zh
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E·珀奇
W·宾德尔
S·莱曼
D·本辛格
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Merck Patent GmbH
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Merck Patent GmbH
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D309/06—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CN2006800179689A 2005-05-25 2006-05-10 通过还原消除相应的4-卤素衍生物而制备2,5-取代的四氢吡喃衍生物的方法 Active CN101180287B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05011323 2005-05-25
EP05011323.2 2005-05-25
PCT/EP2006/004387 WO2006125526A1 (de) 2005-05-25 2006-05-10 Verfahren zur herstellung von 2,5-substituierten tetrahydropyran-derivaten durch reduktive eliminierung des entsprechenden 4-halogen-derivats

Publications (2)

Publication Number Publication Date
CN101180287A CN101180287A (zh) 2008-05-14
CN101180287B true CN101180287B (zh) 2011-10-19

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CN2006800179689A Active CN101180287B (zh) 2005-05-25 2006-05-10 通过还原消除相应的4-卤素衍生物而制备2,5-取代的四氢吡喃衍生物的方法

Country Status (5)

Country Link
JP (1) JP5260279B2 (ko)
KR (1) KR101393783B1 (ko)
CN (1) CN101180287B (ko)
DE (1) DE112006000984A5 (ko)
WO (1) WO2006125526A1 (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021156870A1 (en) * 2020-02-06 2021-08-12 Agan Aroma & Fine Chemicals Ltd. Mixture of 3-hexen-1-ol isomers and a process of preparing same

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101307666B1 (ko) * 2005-05-25 2013-09-16 메르크 파텐트 게엠베하 테트라하이드로피란 유도체의 제조방법
EP1908813B1 (de) * 2006-10-04 2010-11-03 Merck Patent GmbH Flüssigkristallines Medium
JP5444723B2 (ja) 2009-01-16 2014-03-19 Ｊｎｃ株式会社 液晶組成物および液晶表示素子
JP2012111717A (ja) * 2010-11-25 2012-06-14 Ne Chemcat Corp ジクロロメチル基を含有する化合物の製造方法
DE102011122559A1 (de) 2011-01-25 2012-07-26 Merck Patent Gmbh Flüssigkristalline Verbindungen und flüssigkristalline Medien
JP6627515B2 (ja) * 2015-02-06 2020-01-08 Jnc株式会社 ３，６−ジヒドロ−２ｈ−ピランを有する誘電率異方性が負の液晶性化合物、液晶組成物および液晶表示素子
JP6511975B2 (ja) * 2015-06-09 2019-05-15 Jnc株式会社 ジヒドロピラン化合物を含有する液晶組成物および液晶表示素子

Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
ATE374232T1 (de) * 2002-11-27 2007-10-15 Merck Patent Gmbh Flüssigkristalline verbindungen
DE10318420A1 (de) * 2003-04-24 2004-11-11 Merck Patent Gmbh Flüssigkristalline Verbindungen
ATE340836T1 (de) * 2003-05-27 2006-10-15 Merck Patent Gmbh Pyranderivate
EP1482021B1 (en) * 2003-05-27 2007-01-24 MERCK PATENT GmbH Pyrans as liquid crystals
US20050059632A1 (en) * 2003-06-30 2005-03-17 Richard Storer Synthesis of beta-L-2'-deoxy nucleosides
US7704566B2 (en) * 2003-08-04 2010-04-27 Merck Patent Gmbh Liquid crystalline medium
DE102004036068B4 (de) * 2003-08-18 2023-05-17 Merck Patent Gmbh Verfahren zur Hydrierung
WO2005019381A1 (en) * 2003-08-25 2005-03-03 Merck Patent Gmbh Liquid crystalline medium
KR101307666B1 (ko) * 2005-05-25 2013-09-16 메르크 파텐트 게엠베하 테트라하이드로피란 유도체의 제조방법

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HAnshke et al..Ernst Hanschke:zur kenntnis der prins schen reaktioin, III Mitteil: Uber die reaction von allylcarbinol mit aldehyden und ketonen.《Chmische Berichte》.1955,第88卷1053-1061. *
HAnshkeetal..ErnstHanschke:zurkenntnisderprinsschenreaktioin III Mitteil: Uber die reaction von allylcarbinol mit aldehyden und ketonen.《Chmische Berichte》.1955
Pedro O. Miranda et al..Iron(III)-catalyzed prins-type cyclization using homopropargylic alcohol: a method for the synthesis of 2-alkyl-4-halo-5,6-dihydro-2H-pyrans.《Organic Letters》.2003,第5卷(第11期),1979-1982. *
PedroO.Mirandaetal..Iron(III)-catalyzedprins-typecyclizationusinghomopropargylicalcohol:amethodforthesynthesisof2-alkyl-4-halo-5 6-dihydro-2H-pyrans.《Organic Letters》.2003

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021156870A1 (en) * 2020-02-06 2021-08-12 Agan Aroma & Fine Chemicals Ltd. Mixture of 3-hexen-1-ol isomers and a process of preparing same

Also Published As

Publication number Publication date
JP2008545667A (ja) 2008-12-18
WO2006125526A1 (de) 2006-11-30
DE112006000984A5 (de) 2008-04-10
CN101180287A (zh) 2008-05-14
KR20080019018A (ko) 2008-02-29
KR101393783B1 (ko) 2014-05-14
JP5260279B2 (ja) 2013-08-14

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