CN101147584A - Health-care food capable of preventing and treating diabetes and preparation method thereof - Google Patents

Health-care food capable of preventing and treating diabetes and preparation method thereof Download PDF

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Publication number
CN101147584A
CN101147584A CNA2007101663026A CN200710166302A CN101147584A CN 101147584 A CN101147584 A CN 101147584A CN A2007101663026 A CNA2007101663026 A CN A2007101663026A CN 200710166302 A CN200710166302 A CN 200710166302A CN 101147584 A CN101147584 A CN 101147584A
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China
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parts
propolis
root
raw material
kudzu vine
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CNA2007101663026A
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CN101147584B (en
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聂承和
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Xiamen Shencaotang Investment and Development Co., Ltd.
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聂承和
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Abstract

The present invention discloses a health-care food for preventing or curing diabetes type II and its preparation method. It is made up by using ( by weight portion) 25-80 portions of ginseng, 21-82 portions of pueraria root, 19-72 portions of coptis root, 12-43 portions of Chinese yam, 9-15 portions of rehmannia root, 7-52 portions of fetid cassia seed, 5-46 portions of propolis and 5-15 portions of ganoderma polysaccharide through a certain preparation method. Said invention also provides the concrete steps of its preparation method.

Description

Health food of prevention and treatment diabetes and preparation method thereof
Technical field
The present invention relates to a kind of health food, relate in particular to the health food of a kind of prevention and treatment diabetes, the invention still further relates to the preparation method of this health food, belong to field of health care food.
Background technology
Diabetes (DM, Diabetes Mellitus) are a kind of metabolic diseases of multi-pathogenesis, and characteristics are chronic hyperglycemias, follow sugar, fat and protein metabolism disorder because of insulin (Insulin) is secreted and/or the effect defective causes.
Diabetes are the serious metabolic diseases in the whole world, and development rapidly, and wherein type ii diabetes accounts for more than 90% of diabetic.In the world, just there was 1 people to die from diabetes in per 10 seconds, in these 10 seconds, just has 2 people to suffer from diabetes simultaneously.The annual number of suffering from diabetes increases by 7,000,000, and the number of suffering from diabetes in global the same generation people will surpass 3.5 hundred million people, and majority concentrates on the Asia.Diabetes have become a very serious big disease with threatening human health.
By 2007, the whole world estimated that the medical expense of diabetes and complication thereof will reach 2,150 hundred million to 3,750 hundred million dollars.Prevention at present, treatment diabetes medicament and health products mostly are to be made with chemical substance and chemical industry method, its expense height, weak effect, recurrence rate height and great side effect is arranged.Nearly hundred kinds Chinese medicine preparation on the market, real medicable and few.
Summary of the invention
The present invention's technical problem at first to be solved is to overcome the deficiencies in the prior art, and a kind of health food that can effectively prevent or treat type ii diabetes is provided.
The present invention's technical problem at first to be solved is achieved through the following technical solutions:
A kind of health food that can effectively prevent or treat type ii diabetes is mainly made by each raw material of following weight portion: genseng 25-80 part, root of kudzu vine 21-82 part, coptis 19-72 part, Chinese yam 12-43 part, glutinous rehmannia 9-15 part, Fructus Corni 7-29 part, cassia seed 7-52 part, propolis 5-46 part and GL-B 5-15 part;
Preferably, the weight portion of each raw material is: genseng 30-60 part, root of kudzu vine 28-65 part, coptis 25-55 part, Chinese yam 18-35 part, glutinous rehmannia 12-15 part, Fructus Corni 15-20 part, cassia seed 15-35 part, propolis 10-30 part and GL-B 5-12 part;
Preferred, the weight portion of each raw material is: 10 parts of 40 parts of gensengs, 35 parts of the roots of kudzu vine, 28 parts of the coptiss, 20 parts of Chinese yams, 12 parts of glutinous rehmannia, 20 parts of Fructus Cornis, 15 parts of cassia seeds, propolis 15 and GL-Bs.
Genseng: higher nervous activity excitement and process of inhibition are all had humidification.Have antifatigue, reduce blood sugar, promote the biosynthesis of protein RNA, DNA, regulate cholesterol metabolic, promote the hemopoietic system function, alleviate the effects such as infringement of radiation hemopoietic system.
The root of kudzu vine: the Puerarin that is contained in the kudzu root extract can have hypoglycemic ability to adrenolytic blood glucose increasing effect.
The coptis: by suppressing gluconeogenesis or promoting that glycolysis can reduce euglycemia.
Chinese yam: contain a large amount of mucus proteins, and mucus protein has the effect of good reduction blood sugar.
Glutinous rehmannia: the hyperglycaemia that can reduce euglycemia and cause by adrenaline, ammonium chloride.
Fructus Corni: diuresis, hypotensive effect are arranged, shigella dysenteriae, golden yellow coccus and violet trichophyta etc. are had inhibitory action in various degree.
Cassia seed: nature and flavor sweetness and bitterness is slightly cold, be tcm clinical practice commonly used clear liver and improve vision, the good medicine of sharp water defaecation.
GL-B: can replace insulin and suppress disengaging of aliphatic acid, can improve symptoms such as blood sugar, glucose in urine, can alleviate the occurring degree of Non-Insulin Dependent Diabetes Mellitus.
Propolis:, kept the biologically active and the effective ingredient of each raw material to greatest extent in the present invention as antistaling agent.
Used various raw materials all can be bought from market and obtain among the present invention, and its specification is that pharmaceutical grade or food-grade all can.
Another technical problem to be solved by this invention provides a kind of method for preparing above-mentioned health food.
Another technical problem to be solved by this invention is achieved through the following technical solutions:
A kind of method for preparing above-mentioned health food comprises:
(1) takes by weighing each raw material by following weight portion: genseng 25-80 part, root of kudzu vine 21-82 part, coptis 19-72 part, Chinese yam 12-43 part, glutinous rehmannia 9-15 part, Fructus Corni 7-29 part, cassia seed 7-52 part, propolis 5-46 part and GL-B 5-15 part;
(2) genseng, the root of kudzu vine, the coptis, Chinese yam, glutinous rehmannia, Fructus Corni, cassia seed being carried out the ultra micro broken wall respectively pulverizes; The ultra micro broken wall is pulverized resulting each material carry out CO respectively 2Supercritical extract fully mixes back cryogenic freezing under-10 ℃~-30 ℃ temperature with each effective ingredient that extracts;
(3) add GL-B in the material after cryogenic freezing, carry out sonic oscillation and mix, stir; Carry out low temperature drying at-7 ℃~-15 ℃, add propolis afterwards, mixing, oven dry, granulation, promptly.
Among the above-mentioned preparation method, the ultra micro broken wall described in the step (2) is pulverized and preferably carried out in following condition: pulverize temperature and be controlled at-5 ℃~15 ℃, the medium particle diameter of pulverizing each raw material is controlled at below the 10 μ m, and the breaking-wall cell rate is more than or equal to 95%.
Cryogenic freezing described in the step (2) is preferably freezing 4 hours.
The preparation method of pharmaceutical composition of the present invention or health food adopts ultra micro broken wall crushing technology and supercritical extraction technique to combine, with genseng, the root of kudzu vine, the coptis is main material, with Chinese yam, glutinous rehmannia, Fructus Corni, cassia seed is auxiliary material, with the development of biotechnology and new material structures technology new material---GL-B is a synergistic carriers, be prepared from as antistaling agent with propolis, has reduction blood sugar, promote effects such as beta Cell of islet reparation, edible safety is reliable, without any side effects, can effectively prevent or treat type ii diabetes.
The usage of health food of the present invention and consumption: every day 3 times, each oral 0.3g can be according to three blood sugar level suitably adjustment regularly before the meal.
The specific embodiment
Further describe the present invention below in conjunction with specific embodiment, advantage of the present invention and characteristics will be more clear along with description.But these embodiment only are exemplary, scope of the present invention are not constituted any restriction.It will be understood by those skilled in the art that and down can make amendment or replace without departing from the spirit and scope of the present invention, but these modifications and replacing all fall within the scope of protection of the present invention the details of technical solution of the present invention and form.
The preparation of embodiment 1 health food of the present invention
Take by weighing each raw material (unit: g): genseng 25, the root of kudzu vine 21, the coptis 19, Chinese yam 12, glutinous rehmannia 9, Fructus Corni 7, cassia seed 7, propolis 5, GL-B 5 by following weight;
Genseng, the root of kudzu vine, the coptis, Chinese yam, glutinous rehmannia, Fructus Corni, cassia seed are carried out the ultra micro broken wall respectively pulverize, pulverize temperature and be controlled at-5 ℃~15 ℃, the pulverizing medium particle diameter of each raw material is controlled at below the 10 μ m, and the breaking-wall cell rate is more than or equal to 95%; The ultra micro broken wall is pulverized resulting each material carry out CO respectively 2Supercritical extract fully mixes the back-10 ℃~-30 ℃ following cryogenic freezings 4 hours with the effective ingredient that extracts; Add GL-B, carry out sonic oscillation and mix, stir; Carry out low temperature drying at-7 ℃~-15 ℃, add propolis afterwards, mixing, oven dry, granulation incapsulate, promptly.
The preparation of embodiment 2 health foods of the present invention
Take by weighing each raw material (unit: g): genseng 80, the root of kudzu vine 82, the coptis 72, Chinese yam 43, glutinous rehmannia 15, Fructus Corni 29, cassia seed 52, propolis 46, GL-B 15 by following weight;
Genseng, the root of kudzu vine, the coptis, Chinese yam, glutinous rehmannia, Fructus Corni, cassia seed are carried out the ultra micro broken wall respectively pulverize, pulverize temperature and be controlled at-5 ℃~15 ℃, the pulverizing medium particle diameter of each raw material is controlled at below the 10 μ m, and the breaking-wall cell rate is more than or equal to 95%; The ultra micro broken wall is pulverized resulting each material carry out CO respectively 2Supercritical extract fully mixes the back-10 ℃~-30 ℃ following cryogenic freezings 5 hours with the effective ingredient that extracts; Add GL-B, carry out sonic oscillation and mix, stir; Carry out low temperature drying at-7 ℃~-15 ℃, add propolis afterwards, mixing, oven dry, granulation, promptly.
The preparation of embodiment 3 health foods of the present invention
Take by weighing each raw material (unit: g): genseng 40, the root of kudzu vine 35, the coptis 28, Chinese yam 20, glutinous rehmannia 12, Fructus Corni 20, cassia seed 15, propolis 15, GL-B 10 by following weight;
Genseng, the root of kudzu vine, the coptis, Chinese yam, glutinous rehmannia, Fructus Corni, cassia seed are carried out the ultra micro broken wall respectively pulverize, pulverize temperature and be controlled at-5 ℃~15 ℃, the pulverizing medium particle diameter of each raw material is controlled at below the 10 μ m, and the breaking-wall cell rate is more than or equal to 95%; The ultra micro broken wall is pulverized resulting material carry out CO respectively 2Supercritical extract fully mixes the back-10 ℃~-30 ℃ following cryogenic freezings 4 hours with the effective ingredient that extracts; Add GL-B, carry out sonic oscillation and mix, stir; Carry out low temperature drying at-7 ℃~-15 ℃, add propolis afterwards, mixing, oven dry, granulation, promptly.
The health-care efficacy viewing test of test example 1 health food of the present invention
One, the object of observation: 60 routine patients are the type ii diabetes patient who makes a definite diagnosis, wherein, and male 31 examples, women 29 examples, 61 years old mean age, all voluntary participation test-meal tests.
Two, the prepared health products of eating method and consumption: embodiment of the invention 1-3, every day 3 times, each oral 0.3g took three months, can be according to three blood sugar level suitably adjustment regularly before the meal.
Three, model case
The patient: open * *, the woman, medical history 10 years, symptom: biped is sent out cool sense and companion fiber crops pain.Diagnosis: diabetes type II.Diabetic peripheral neuropathy (late period).Take health food of the present invention, every day 3 times, each 0.3g, taking three months is three courses of treatment.Symptom after edible: biped sends out cool sense and companion fiber crops pain disappears.
Four, observed result
Take health product for treating 60 routine type ii diabetes patients of the present invention, after taking three months, treatment back fasting blood-glucose is 117.19 ± 25.98mg/dl, preceding 208.65 ± the 51.68mg/dl of treatment obviously descend (P<0.01), patient's clinical symptoms disappears substantially, serum insulin level rises significantly (P<0.01), and total effective rate is 90%.The normal person's blood sugar level of blood sugar there is not obvious influence.
Follow up a case by regular visits to 17 examples, the curative effect when 11 examples are kept treatment.Obvious blood sugar decreasing effect is also arranged in experimental study, the repair of the beta Cell of islet of promotion is arranged.

Claims (6)

1. a health food that prevents or treat type ii diabetes is mainly made by each raw material of following weight portion: genseng 25-80 part, root of kudzu vine 21-82 part, coptis 19-72 part, Chinese yam 12-43 part, glutinous rehmannia 9-15 part, Fructus Corni 7-29 part, cassia seed 7-52 part, propolis 5-46 part and GL-B 5-15 part.
2. according to the health food of claim 1, it is characterized in that the weight portion of each raw material is: genseng 30-60 part, root of kudzu vine 28-65 part, coptis 25-55 part, Chinese yam 18-35 part, glutinous rehmannia 12-15 part, Fructus Corni 15-20 part, cassia seed 15-35 part, propolis 10-30 part and GL-B 5-12 part.
3. according to the health food of claim 2, it is characterized in that the weight portion of each raw material is: 10 parts of 40 parts of gensengs, 35 parts of the roots of kudzu vine, 28 parts of the coptiss, 20 parts of Chinese yams, 12 parts of glutinous rehmannia, 20 parts of Fructus Cornis, 15 parts of cassia seeds, propolis 15 and GL-Bs.
4. method for preparing the described health food of claim 1 comprises:
(1) takes by weighing each raw material by following weight portion: genseng 25-80 part, root of kudzu vine 21-82 part, coptis 19-72 part, Chinese yam 12-43 part, glutinous rehmannia 9-15 part, Fructus Corni 7-29 part, cassia seed 7-52 part, propolis 5-46 part and GL-B 5-15 part;
(2) genseng, the root of kudzu vine, the coptis, Chinese yam, glutinous rehmannia, Fructus Corni, cassia seed being carried out the ultra micro broken wall respectively pulverizes; The ultra micro broken wall is pulverized resulting each material carry out CO respectively 2Supercritical extract, each effective ingredient that extraction is obtained fully mixes back cryogenic freezing under-10 ℃~-30 ℃ temperature;
(3) in through the material after the cryogenic freezing, add GL-B, carry out sonic oscillation and mix, stir; Under-7 ℃~-15 ℃ temperature, carry out low temperature drying, add propolis, mixing, oven dry, granulation, promptly.
5. according to the described method of claim 4, it is characterized in that, it is to carry out in following condition that ultra micro broken wall described in the step (2) is pulverized: the ultra micro broken wall is pulverized temperature and is controlled at-5 ℃~15 ℃, and the medium particle diameter of pulverizing each raw material is controlled at below the 10 μ m, and the breaking-wall cell rate is more than or equal to 95%.
6. according to the described method of claim 4, it is characterized in that the time of the cryogenic freezing described in the step (2) is 4 hours.
CN2007101663026A 2007-11-05 2007-11-05 Health-care food capable of preventing and treating diabetes and preparation method thereof Expired - Fee Related CN101147584B (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102113529A (en) * 2010-12-31 2011-07-06 王钢柱 Flour with function of treating diabetes and preparation method thereof
CN102423077A (en) * 2011-11-28 2012-04-25 李忠义 Diabetes functional beverage gamma balance liquid
CN101695376B (en) * 2009-10-14 2012-05-30 寇开勤 Health-care food for preventing diabetes
CN103637281A (en) * 2013-11-21 2014-03-19 威海五谷怡健食品有限公司 Functional food for postpartum lactogenesis and lactation promotion and preparation method thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1306830A (en) * 2000-02-01 2001-08-08 谷越秀 Medicine for treating Type-11 diabetes
CN1263488C (en) * 2004-12-29 2006-07-12 王四旺 Capsule of dual gen-sengs and preparing technique

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101695376B (en) * 2009-10-14 2012-05-30 寇开勤 Health-care food for preventing diabetes
CN102113529A (en) * 2010-12-31 2011-07-06 王钢柱 Flour with function of treating diabetes and preparation method thereof
CN102113529B (en) * 2010-12-31 2014-02-12 王钢柱 Flour with function of treating diabetes and preparation method thereof
CN102423077A (en) * 2011-11-28 2012-04-25 李忠义 Diabetes functional beverage gamma balance liquid
CN102423077B (en) * 2011-11-28 2013-07-03 李忠义 Diabetes functional beverage
CN103637281A (en) * 2013-11-21 2014-03-19 威海五谷怡健食品有限公司 Functional food for postpartum lactogenesis and lactation promotion and preparation method thereof

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