CN101137355B - 无纤维经皮治疗系统及其制备方法 - Google Patents
无纤维经皮治疗系统及其制备方法 Download PDFInfo
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- CN101137355B CN101137355B CN2006800072183A CN200680007218A CN101137355B CN 101137355 B CN101137355 B CN 101137355B CN 2006800072183 A CN2006800072183 A CN 2006800072183A CN 200680007218 A CN200680007218 A CN 200680007218A CN 101137355 B CN101137355 B CN 101137355B
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Classifications
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- A—HUMAN NECESSITIES
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
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- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
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- A—HUMAN NECESSITIES
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- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
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- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE200510010255 DE102005010255A1 (de) | 2005-03-07 | 2005-03-07 | Faserfreies transdermales therapeutisches System und Verfahren zu seiner Herstellung |
| DE102005010255.7 | 2005-03-07 | ||
| PCT/EP2006/001840 WO2006094681A1 (de) | 2005-03-07 | 2006-02-28 | Faserfreies transdermales therapeutisches system und verfahren zu seiner herstellung |
Publications (2)
| Publication Number | Publication Date |
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| CN101137355A CN101137355A (zh) | 2008-03-05 |
| CN101137355B true CN101137355B (zh) | 2012-10-10 |
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| CN2006800072183A Expired - Fee Related CN101137355B (zh) | 2005-03-07 | 2006-02-28 | 无纤维经皮治疗系统及其制备方法 |
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| US (2) | US11311495B2 (enExample) |
| EP (1) | EP1855660B2 (enExample) |
| JP (1) | JP5308149B2 (enExample) |
| KR (1) | KR20070110093A (enExample) |
| CN (1) | CN101137355B (enExample) |
| AT (1) | ATE517616T1 (enExample) |
| AU (1) | AU2006222242B2 (enExample) |
| BR (1) | BRPI0608067B1 (enExample) |
| CA (1) | CA2598353C (enExample) |
| DE (1) | DE102005010255A1 (enExample) |
| ES (1) | ES2368940T5 (enExample) |
| IL (1) | IL185686A (enExample) |
| MX (1) | MX2007010900A (enExample) |
| NZ (1) | NZ561219A (enExample) |
| RU (1) | RU2386435C2 (enExample) |
| WO (1) | WO2006094681A1 (enExample) |
| ZA (1) | ZA200706885B (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL177071A0 (en) * | 2005-08-01 | 2006-12-10 | Nitto Denko Corp | Method of preparing a nicotine transdermal preparation |
| DE102006054732B4 (de) | 2006-11-21 | 2010-12-30 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System mit Ionenpaar-Mikroreservoiren |
| AU2009298411B2 (en) | 2008-10-02 | 2013-06-06 | Mylan Inc. | Method of making a multilayer adhesive laminate |
| CN101956005B (zh) * | 2010-08-13 | 2012-07-25 | 司法部司法鉴定科学技术研究所 | 一种荧光标记的插入缺失遗传多态性位点复合扩增系统及其应用 |
| EP2457565A1 (de) * | 2010-11-29 | 2012-05-30 | Ratiopharm GmbH | Transdermales therapeutisches System enthaltend Rotigotin |
| WO2012074988A1 (en) * | 2010-12-02 | 2012-06-07 | Ratiopharm Gmbh | Rotigotine ionic liquid |
| WO2012158483A2 (en) | 2011-05-16 | 2012-11-22 | Avery Dennison Corporation | Adhesive containing microparticles |
| KR102242908B1 (ko) | 2013-02-07 | 2021-04-20 | 애버리 데니슨 코포레이션 | 개선된 특성을 지니는 항미생물 접착제 |
| WO2014151355A1 (en) | 2013-03-15 | 2014-09-25 | Avery Dennison Corporation | Transparent cover dressing application system and inclusion of label strip |
| KR101686987B1 (ko) * | 2013-05-30 | 2016-12-15 | 에스케이케미칼주식회사 | 로티고틴과 지방산 및 스티렌 점착제를 함유한 경피치료시스템 |
| EP2946775A1 (de) | 2014-05-20 | 2015-11-25 | LTS LOHMANN Therapie-Systeme AG | Lavendelöl enthaltendes transdermales therapeutisches System |
| EP3789014A1 (en) | 2014-06-05 | 2021-03-10 | Avery Dennison Corporation | Articles with active agent concentrated at the substrate contacting surface and related methods |
| DE102015200705A1 (de) | 2015-01-19 | 2016-07-21 | Zf Friedrichshafen Ag | Hydropneumatische Federung mit passiv lastabhängiger Dämpfventilverstellung |
| CN105147642B (zh) * | 2015-07-31 | 2018-02-16 | 大连理工大学 | 一种含福莫特罗或其富马酸盐的透皮贴剂 |
| CN105505308A (zh) * | 2015-12-19 | 2016-04-20 | 仇颖超 | 一种纯天然热熔压敏胶的制备方法 |
| DE102017104026A1 (de) * | 2017-02-27 | 2018-08-30 | Lts Lohmann Therapie-Systeme Ag | Nicotin enthaltendes transparentes transdermales therapeutisches System |
| DE102017127433A1 (de) * | 2017-11-21 | 2019-05-23 | Lts Lohmann Therapie-Systeme Ag | TTS auf Basis von klebenden Weichmacher-Polymer-Matrices |
| DE102019117310A1 (de) * | 2019-06-27 | 2020-12-31 | Lts Lohmann Therapie-Systeme Ag | Verfahren zur Herstellung von Wirkstoffverabreichungssystemen mittels Tampondruckverfahren |
| US20220175812A1 (en) | 2020-12-03 | 2022-06-09 | Battelle Memorial Institute | Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery |
| JP2024516108A (ja) | 2021-04-07 | 2024-04-12 | バテル・メモリアル・インスティテュート | 非ウイルス性担体を同定および使用するための迅速な設計、構築、試験、および学習技術 |
| WO2025072751A1 (en) | 2023-09-29 | 2025-04-03 | Battelle Memorial Institute | Polymer nanoparticle compositions for in vivo expression of polypeptides |
| US12441996B2 (en) | 2023-12-08 | 2025-10-14 | Battelle Memorial Institute | Use of DNA origami nanostructures for molecular information based data storage systems |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5110599A (en) * | 1987-08-14 | 1992-05-05 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Process for producing an administration and/or dosage form for medicinal active substances by means of a printing process |
| CN1143314A (zh) * | 1994-03-07 | 1997-02-19 | 瑟拉技术有限公司 | 含药物的粘着复合的透皮给药药贴 |
| US5820876A (en) * | 1986-08-28 | 1998-10-13 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Transdermal therapeutic system |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US500461A (en) | 1893-06-27 | Clothes-pounder | ||
| DE3315272C2 (de) * | 1983-04-27 | 1986-03-27 | Lohmann Gmbh & Co Kg, 5450 Neuwied | Pharmazeutisches Produkt und Verfahren zu seiner Herstellung |
| JPS61251619A (ja) * | 1985-04-30 | 1986-11-08 | Nitto Electric Ind Co Ltd | ニコチン含有テ−プ製剤 |
| US6126963A (en) * | 1986-08-28 | 2000-10-03 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Transdermal therapeutic system, its use and production process |
| DE3629304A1 (de) * | 1986-08-28 | 1988-03-24 | Lohmann Gmbh & Co Kg | Transdermales therapeutisches system, seine verwendung und verfahren zu seiner herstellung |
| US5004610A (en) | 1988-06-14 | 1991-04-02 | Alza Corporation | Subsaturated nicotine transdermal therapeutic system |
| DE4400769C2 (de) | 1994-01-13 | 1996-07-18 | Lohmann Therapie Syst Lts | Verfahren und Vorrichtung zur Herstellung einer flächigen Darreichungsform mit einer Arzneimittelwirkstoffe enthaltenden Zubereitung |
| DE19826592A1 (de) | 1998-06-15 | 1999-12-16 | Lohmann Therapie Syst Lts | Verfahren zur Herstellung eines aus einzelnen Schichten bestehenden Laminats |
| DE69941629D1 (de) * | 1998-12-18 | 2009-12-17 | Alza Corp | Durchsichtige transdermale nicotinabgabevorrichtungen |
| DE19918106A1 (de) | 1999-04-22 | 2000-10-26 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit neutralisierten Acrylathaftklebern |
| DE10018834A1 (de) | 2000-04-15 | 2001-10-25 | Lohmann Therapie Syst Lts | Transdermale oder transmucosale Darreichungsformen mit einer nicotinhaltigen Wirkstoffkombination zur Raucherentwöhnung |
| DE10053375C1 (de) | 2000-10-27 | 2002-01-24 | Lohmann Therapie Syst Lts | Transdermale therapeutische Systeme mit lichtempfindlichen Wirkstoffen |
| DE10110391A1 (de) * | 2001-03-03 | 2002-09-26 | Lohmann Therapie Syst Lts | Hochflexibles Nikotin transdermales therapeutisches System mit Nikotin als Wirkstoff |
| DE10317692A1 (de) * | 2003-04-17 | 2004-11-11 | Lts Lohmann Therapie-Systeme Ag | Medizinische Wirkstoffpflaster mit veringerter optischer Auffälligkeit auf der Haut |
-
2005
- 2005-03-07 DE DE200510010255 patent/DE102005010255A1/de not_active Withdrawn
-
2006
- 2006-02-28 EP EP06723143.1A patent/EP1855660B2/de not_active Not-in-force
- 2006-02-28 RU RU2007135599A patent/RU2386435C2/ru active
- 2006-02-28 AU AU2006222242A patent/AU2006222242B2/en not_active Ceased
- 2006-02-28 WO PCT/EP2006/001840 patent/WO2006094681A1/de not_active Ceased
- 2006-02-28 ES ES06723143T patent/ES2368940T5/es active Active
- 2006-02-28 KR KR20077021601A patent/KR20070110093A/ko not_active Ceased
- 2006-02-28 NZ NZ561219A patent/NZ561219A/en not_active IP Right Cessation
- 2006-02-28 BR BRPI0608067-7A patent/BRPI0608067B1/pt not_active IP Right Cessation
- 2006-02-28 CA CA 2598353 patent/CA2598353C/en active Active
- 2006-02-28 US US11/885,716 patent/US11311495B2/en active Active
- 2006-02-28 MX MX2007010900A patent/MX2007010900A/es active IP Right Grant
- 2006-02-28 AT AT06723143T patent/ATE517616T1/de active
- 2006-02-28 CN CN2006800072183A patent/CN101137355B/zh not_active Expired - Fee Related
- 2006-02-28 JP JP2008500087A patent/JP5308149B2/ja not_active Expired - Fee Related
-
2007
- 2007-08-17 ZA ZA200706885A patent/ZA200706885B/xx unknown
- 2007-09-03 IL IL185686A patent/IL185686A/en not_active IP Right Cessation
-
2019
- 2019-09-20 US US16/577,473 patent/US11478434B2/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5820876A (en) * | 1986-08-28 | 1998-10-13 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Transdermal therapeutic system |
| US5110599A (en) * | 1987-08-14 | 1992-05-05 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Process for producing an administration and/or dosage form for medicinal active substances by means of a printing process |
| CN1143314A (zh) * | 1994-03-07 | 1997-02-19 | 瑟拉技术有限公司 | 含药物的粘着复合的透皮给药药贴 |
Also Published As
| Publication number | Publication date |
|---|---|
| NZ561219A (en) | 2010-09-30 |
| WO2006094681A1 (de) | 2006-09-14 |
| ZA200706885B (en) | 2008-06-25 |
| EP1855660B2 (de) | 2019-10-16 |
| CN101137355A (zh) | 2008-03-05 |
| JP5308149B2 (ja) | 2013-10-09 |
| JP2008531742A (ja) | 2008-08-14 |
| CA2598353A1 (en) | 2006-09-14 |
| BRPI0608067A2 (pt) | 2010-11-09 |
| IL185686A0 (en) | 2008-01-06 |
| EP1855660B1 (de) | 2011-07-27 |
| US20080233177A1 (en) | 2008-09-25 |
| CA2598353C (en) | 2013-07-09 |
| US20200009073A1 (en) | 2020-01-09 |
| ES2368940T3 (es) | 2011-11-23 |
| AU2006222242B2 (en) | 2011-03-31 |
| US11478434B2 (en) | 2022-10-25 |
| US11311495B2 (en) | 2022-04-26 |
| IL185686A (en) | 2012-02-29 |
| ES2368940T5 (es) | 2020-04-20 |
| ATE517616T1 (de) | 2011-08-15 |
| MX2007010900A (es) | 2007-12-06 |
| HK1105368A1 (en) | 2008-02-15 |
| RU2386435C2 (ru) | 2010-04-20 |
| EP1855660A1 (de) | 2007-11-21 |
| KR20070110093A (ko) | 2007-11-15 |
| RU2007135599A (ru) | 2009-04-10 |
| DE102005010255A1 (de) | 2006-09-14 |
| BRPI0608067B1 (pt) | 2022-05-10 |
| AU2006222242A1 (en) | 2006-09-14 |
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