CN101111246A - 芳基吡咯烷酮的合成 - Google Patents

芳基吡咯烷酮的合成 Download PDF

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Publication number
CN101111246A
CN101111246A CNA2006800035536A CN200680003553A CN101111246A CN 101111246 A CN101111246 A CN 101111246A CN A2006800035536 A CNA2006800035536 A CN A2006800035536A CN 200680003553 A CN200680003553 A CN 200680003553A CN 101111246 A CN101111246 A CN 101111246A
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CN
China
Prior art keywords
substituted
unsubstituted
group
heteroaryl
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2006800035536A
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English (en)
Chinese (zh)
Inventor
贺耘
D·伍德曼西
崔夏洵
王志成
吴报根
T·源
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IRM LLC
Original Assignee
IRM LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IRM LLC filed Critical IRM LLC
Publication of CN101111246A publication Critical patent/CN101111246A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CNA2006800035536A 2005-01-28 2006-01-30 芳基吡咯烷酮的合成 Pending CN101111246A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64803905P 2005-01-28 2005-01-28
US60/648,039 2005-01-28
PCT/US2006/003240 WO2006081562A2 (en) 2005-01-28 2006-01-30 Synthesis of aryl pyrrolidones

Publications (1)

Publication Number Publication Date
CN101111246A true CN101111246A (zh) 2008-01-23

Family

ID=36741151

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2006800035536A Pending CN101111246A (zh) 2005-01-28 2006-01-30 芳基吡咯烷酮的合成

Country Status (10)

Country Link
EP (1) EP1841424A4 (https=)
JP (1) JP2008528625A (https=)
KR (1) KR100890696B1 (https=)
CN (1) CN101111246A (https=)
AU (1) AU2006209241B2 (https=)
BR (1) BRPI0607294A2 (https=)
CA (1) CA2593816A1 (https=)
MX (1) MX2007008974A (https=)
RU (1) RU2007132260A (https=)
WO (1) WO2006081562A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101979378A (zh) * 2010-10-13 2011-02-23 中国科学院上海有机化学研究所 一种手性γ-内酰胺化合物的合成方法

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* Cited by examiner, † Cited by third party
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CA2799154A1 (en) 2010-05-12 2011-11-17 Abbvie Inc. Indazole inhibitors of kinase
RU2485100C1 (ru) * 2012-02-07 2013-06-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Пермский государственный национальный исследовательский университет" 1-арил-4-бензоил-3-гидрокси-5-метоксикарбонил-2,5-дигидро-1н-пиррол-2-оны, проявляющие анальгетическую активность, и способ их получения
US11589583B2 (en) 2013-12-03 2023-02-28 Fmc Corporation Pyrrolidinones herbicides
CA2931961C (en) 2013-12-03 2023-10-31 Andrew Duncan Satterfield Pyrrolidinones as herbicides
SG11201610720VA (en) 2014-07-02 2017-01-27 Du Pont Piperidinone herbicides
CN107001260B (zh) 2014-12-08 2020-11-10 Fmc公司 3-氧基-3-(芳氨基)丙酸酯、其制备方法、以及其在制备吡咯烷酮中的用途
EP3280709B1 (en) 2015-04-10 2021-05-26 FMC Corporation Substituted cyclic amides as herbicides
BR112017020094B1 (pt) 2015-04-27 2022-01-11 Fmc Corporation Composto, composições herbicidas, mistura de herbicida e método para controlar o crescimento de vegetação indesejada
JP7000160B2 (ja) 2015-05-12 2022-01-19 エフ エム シー コーポレーション 除草剤としてのアリール置換二環式化合物
JP6869192B2 (ja) 2015-05-29 2021-05-12 エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ 除草剤としての置換環状アミド
CN107709310B (zh) 2015-06-02 2021-09-24 Fmc公司 取代的环酰胺及其作为除草剂的用途
JP6937290B2 (ja) 2015-07-31 2021-09-22 エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ 除草剤として有用な環状ｎ−カルボキサミド化合物
RU2019122791A (ru) 2016-12-21 2021-01-25 Фмк Корпорейшн Гербициды на основе нитрона
CN110740646B (zh) 2017-03-21 2022-05-10 Fmc公司 除草剂混合物、组合物和方法
MX2019010969A (es) 2017-03-21 2019-12-02 Fmc Corp Pirrolidinonas y proceso para prepararlas.
AR111839A1 (es) 2017-05-30 2019-08-21 Fmc Corp Lactamas 3-sustituidas herbicidas
AR111967A1 (es) 2017-05-30 2019-09-04 Fmc Corp Amidas herbicidas
CN116782894A (zh) * 2020-10-06 2023-09-19 D.E.肖研究有限责任公司 作为Kv1.3钾Shaker通道阻断剂的内酰胺化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3058986A (en) * 1962-10-16 N-ammoalkyl-x-phenyl-x-lower alkyl-z-
US3956314A (en) * 1970-07-24 1976-05-11 U.C.B., Societe Anonyme Derivatives of 2-pyrrolidinone
US3956914A (en) * 1974-11-14 1976-05-18 The Marison Company Spin lathe
JP2002363160A (ja) * 2001-06-05 2002-12-18 Sumitomo Chem Co Ltd 光学活性４−アリール−２−ピペリジノン類の製造方法
US7495016B2 (en) * 2002-10-21 2009-02-24 Irm Llc Pyrrolidones with anti-HIV activity
JP4351859B2 (ja) * 2003-04-14 2009-10-28 三菱レイヨン株式会社 光学活性β−アリ−ル化合物の製造法
WO2006081554A2 (en) * 2005-01-28 2006-08-03 Irm Llc Phenyl-substituted pyrrolidones

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101979378A (zh) * 2010-10-13 2011-02-23 中国科学院上海有机化学研究所 一种手性γ-内酰胺化合物的合成方法

Also Published As

Publication number Publication date
WO2006081562A3 (en) 2006-10-19
EP1841424A2 (en) 2007-10-10
KR20070097555A (ko) 2007-10-04
JP2008528625A (ja) 2008-07-31
CA2593816A1 (en) 2006-08-03
BRPI0607294A2 (pt) 2009-08-25
AU2006209241A1 (en) 2006-08-03
EP1841424A4 (en) 2010-01-27
WO2006081562A2 (en) 2006-08-03
AU2006209241B2 (en) 2009-10-22
RU2007132260A (ru) 2009-03-10
KR100890696B1 (ko) 2009-03-26
MX2007008974A (es) 2007-09-18

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Open date: 20080123