CN101102792A - 治疗多发性硬化 - Google Patents
治疗多发性硬化 Download PDFInfo
- Publication number
- CN101102792A CN101102792A CNA2005800468858A CN200580046885A CN101102792A CN 101102792 A CN101102792 A CN 101102792A CN A2005800468858 A CNA2005800468858 A CN A2005800468858A CN 200580046885 A CN200580046885 A CN 200580046885A CN 101102792 A CN101102792 A CN 101102792A
- Authority
- CN
- China
- Prior art keywords
- vla
- antibody
- experimenter
- reagent
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/215—IFN-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62970004P | 2004-11-19 | 2004-11-19 | |
| US60/629,700 | 2004-11-19 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2013100542015A Division CN103169965A (zh) | 2004-11-19 | 2005-11-18 | 治疗多发性硬化 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101102792A true CN101102792A (zh) | 2008-01-09 |
Family
ID=36407818
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2005800468858A Pending CN101102792A (zh) | 2004-11-19 | 2005-11-18 | 治疗多发性硬化 |
| CN2013100542015A Pending CN103169965A (zh) | 2004-11-19 | 2005-11-18 | 治疗多发性硬化 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2013100542015A Pending CN103169965A (zh) | 2004-11-19 | 2005-11-18 | 治疗多发性硬化 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20090202527A1 (enExample) |
| EP (2) | EP2808033A1 (enExample) |
| JP (4) | JP2008520717A (enExample) |
| CN (2) | CN101102792A (enExample) |
| AU (1) | AU2005306399B2 (enExample) |
| CA (1) | CA2587597A1 (enExample) |
| HK (1) | HK1203055A1 (enExample) |
| WO (1) | WO2006055871A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103038257A (zh) * | 2010-04-16 | 2013-04-10 | 比奥根艾迪克Ma公司 | 抗vla-4抗体 |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19853487A1 (de) | 1998-11-19 | 2000-05-25 | Fumapharm Ag Muri | Verwendung von Dialkylfumaraten |
| ATE380027T1 (de) | 2003-09-09 | 2007-12-15 | Fumapharm Ag | Verwendung von fumarsäure-derivaten zur behandlung von herzinsuffizienz und asthma |
| EP1833509A4 (en) * | 2004-12-03 | 2008-12-03 | Biogen Idec Inc | DELAYING OR PREVENTING THE APPEARANCE OF MULTIPLE SCLEROSIS |
| ES2916604T1 (es) | 2007-02-08 | 2022-07-04 | Biogen Ma Inc | Ensayos de detección de nrf2 y métodos y composiciones relacionados |
| BRPI0814252B8 (pt) * | 2007-06-14 | 2021-05-25 | Biogen Idec Inc | composição farmacêutica aquosa estável compreendendo natalizumabe, dose unitária, e seringa pré-cheia |
| AU2014285086A1 (en) * | 2013-07-05 | 2016-01-21 | Biogen Ma Inc. | Compositions and methods for treatment of stroke |
| CA2979397A1 (en) | 2015-03-12 | 2016-09-15 | Board Of Trustees Of Michigan State University | Compositions and methods for measuring c-peptide binding and diagnosing immune-mediated diseases |
| EP3411065B1 (en) | 2016-02-05 | 2021-03-31 | Orionis Biosciences BV | Clec9a binding agents |
| US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
| US12370233B2 (en) | 2016-08-31 | 2025-07-29 | Mapi Pharma Ltd. | Depot systems comprising glatiramer acetate |
| US10906985B2 (en) | 2017-02-06 | 2021-02-02 | Orionis Biosciences, Inc. | Targeted engineered interferon and uses thereof |
| EP3577133A1 (en) | 2017-02-06 | 2019-12-11 | Orionis Biosciences NV | Targeted chimeric proteins and uses thereof |
| WO2018178973A1 (en) | 2017-03-26 | 2018-10-04 | Mapi Pharma Ltd. | Glatiramer depot systems for treating progressive forms of multiple sclerosis |
| WO2019018688A1 (en) | 2017-07-20 | 2019-01-24 | The University Of Virginia Patent Foundation | METHODS OF TREATING OR PREVENTING A NEUROLOGICAL DISORDER OF THE IMMUNE SYSTEM |
| WO2019148089A1 (en) | 2018-01-26 | 2019-08-01 | Orionis Biosciences Inc. | Xcr1 binding agents and uses thereof |
| CN119080931A (zh) | 2018-06-04 | 2024-12-06 | 马萨诸塞州渤健公司 | 具有降低的效应功能的抗vla-4抗体 |
| US12410225B2 (en) | 2018-11-08 | 2025-09-09 | Orionis Biosciences, Inc | Modulation of dendritic cell lineages |
| EP3911363A1 (en) * | 2019-01-14 | 2021-11-24 | University of Virginia Patent Foundation | Use of integrin inhibitors for treatment or prevention of a neurological immunity disorder and/or nervous system injury |
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| WO1995019790A1 (en) * | 1994-01-25 | 1995-07-27 | Athena Neurosciences, Inc. | Humanized antibodies against leukocyte adhesion molecule vla-4 |
| US20040009169A1 (en) * | 2002-02-25 | 2004-01-15 | Julie Taylor | Administration of agents for the treatment of inflammation |
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| US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4475196A (en) | 1981-03-06 | 1984-10-02 | Zor Clair G | Instrument for locating faults in aircraft passenger reading light and attendant call control system |
| US4447233A (en) | 1981-04-10 | 1984-05-08 | Parker-Hannifin Corporation | Medication infusion pump |
| US4439196A (en) | 1982-03-18 | 1984-03-27 | Merck & Co., Inc. | Osmotic drug delivery system |
| US4447224A (en) | 1982-09-20 | 1984-05-08 | Infusaid Corporation | Variable flow implantable infusion apparatus |
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-
2005
- 2005-11-18 CN CNA2005800468858A patent/CN101102792A/zh active Pending
- 2005-11-18 JP JP2007543322A patent/JP2008520717A/ja active Pending
- 2005-11-18 EP EP14174866.5A patent/EP2808033A1/en not_active Withdrawn
- 2005-11-18 EP EP05824954A patent/EP1827491A4/en not_active Ceased
- 2005-11-18 CN CN2013100542015A patent/CN103169965A/zh active Pending
- 2005-11-18 US US11/719,660 patent/US20090202527A1/en not_active Abandoned
- 2005-11-18 WO PCT/US2005/042052 patent/WO2006055871A2/en not_active Ceased
- 2005-11-18 AU AU2005306399A patent/AU2005306399B2/en not_active Ceased
- 2005-11-18 CA CA002587597A patent/CA2587597A1/en not_active Abandoned
-
2008
- 2008-11-18 JP JP2008294839A patent/JP2009091360A/ja active Pending
-
2012
- 2012-08-29 JP JP2012188532A patent/JP2012233009A/ja active Pending
-
2014
- 2014-12-08 JP JP2014247885A patent/JP2015044873A/ja active Pending
-
2015
- 2015-04-13 HK HK15103598.3A patent/HK1203055A1/en unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995019790A1 (en) * | 1994-01-25 | 1995-07-27 | Athena Neurosciences, Inc. | Humanized antibodies against leukocyte adhesion molecule vla-4 |
| US20040009169A1 (en) * | 2002-02-25 | 2004-01-15 | Julie Taylor | Administration of agents for the treatment of inflammation |
Non-Patent Citations (1)
| Title |
|---|
| SANDBORN WILLIAM J ET AL: "Efficacy assessment of natalizumab in patients with Crohn′s disease and prior history of anti-TNF therapy: Results from ENACT-1", 《DATABASE BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA,PA,US,DATABASE ACCESSION NO. PREV200600083374》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103038257A (zh) * | 2010-04-16 | 2013-04-10 | 比奥根艾迪克Ma公司 | 抗vla-4抗体 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103169965A (zh) | 2013-06-26 |
| JP2008520717A (ja) | 2008-06-19 |
| JP2009091360A (ja) | 2009-04-30 |
| AU2005306399B2 (en) | 2012-02-09 |
| EP1827491A4 (en) | 2010-07-14 |
| HK1203055A1 (en) | 2015-10-16 |
| US20090202527A1 (en) | 2009-08-13 |
| JP2015044873A (ja) | 2015-03-12 |
| AU2005306399A1 (en) | 2006-05-26 |
| WO2006055871A2 (en) | 2006-05-26 |
| WO2006055871A3 (en) | 2006-08-03 |
| CA2587597A1 (en) | 2006-05-26 |
| JP2012233009A (ja) | 2012-11-29 |
| EP2808033A1 (en) | 2014-12-03 |
| EP1827491A2 (en) | 2007-09-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C53 | Correction of patent of invention or patent application | ||
| CB02 | Change of applicant information |
Address after: Massachusetts, USA Applicant after: Than Ao Gen MA company Address before: Massachusetts, USA Applicant before: Biogen Idec MA Inc. |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: APPLICANT; FROM: BIOGEN IDEC MA TO: BIOGEN MA INC. Free format text: CORRECT: ADDRESS; FROM: |
|
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20080109 |