CN101094697B - 用寻靶因子进行工程改造 - Google Patents

用寻靶因子进行工程改造 Download PDF

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Publication number
CN101094697B
CN101094697B CN2005800382236A CN200580038223A CN101094697B CN 101094697 B CN101094697 B CN 101094697B CN 2005800382236 A CN2005800382236 A CN 2005800382236A CN 200580038223 A CN200580038223 A CN 200580038223A CN 101094697 B CN101094697 B CN 101094697B
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China
Prior art keywords
fibrinogen
cell
ligand
region
factor
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Expired - Fee Related
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CN2005800382236A
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English (en)
Chinese (zh)
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CN101094697A (zh
Inventor
W·弗莱蒙
G·德菲瑟尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alpha Alpha A Joint Stock Ltd
Katholieke Universiteit Leuven
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Alpha Alpha A Joint Stock Ltd
Katholieke Universiteit Leuven
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Publication of CN101094697A publication Critical patent/CN101094697A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3625—Vascular tissue, e.g. heart valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645—Connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Vascular Medicine (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Prostheses (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Filters For Electric Vacuum Cleaners (AREA)
  • Fittings On The Vehicle Exterior For Carrying Loads, And Devices For Holding Or Mounting Articles (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Emergency Lowering Means (AREA)
  • Helmets And Other Head Coverings (AREA)
  • Ladders (AREA)
CN2005800382236A 2004-11-08 2005-11-08 用寻靶因子进行工程改造 Expired - Fee Related CN101094697B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0424560.1 2004-11-08
GB0424560A GB0424560D0 (en) 2004-11-08 2004-11-08 Heart valve tissue engineering
US66076605P 2005-03-11 2005-03-11
US60/660,766 2005-03-11
PCT/BE2005/000158 WO2006047841A2 (en) 2004-11-08 2005-11-08 Engineering with homing factors

Publications (2)

Publication Number Publication Date
CN101094697A CN101094697A (zh) 2007-12-26
CN101094697B true CN101094697B (zh) 2011-08-10

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN2005800382236A Expired - Fee Related CN101094697B (zh) 2004-11-08 2005-11-08 用寻靶因子进行工程改造

Country Status (12)

Country Link
US (1) US20070264306A1 (enExample)
EP (2) EP1812088B1 (enExample)
JP (1) JP4854670B2 (enExample)
CN (1) CN101094697B (enExample)
AT (2) ATE556728T1 (enExample)
AU (1) AU2005301111B2 (enExample)
CA (1) CA2582155A1 (enExample)
DK (2) DK2255834T3 (enExample)
ES (2) ES2385785T3 (enExample)
GB (1) GB0424560D0 (enExample)
PL (1) PL2255834T3 (enExample)
WO (1) WO2006047841A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007145844A (ja) * 2005-11-28 2007-06-14 Lifescan Inc 細胞移植のための血管形成環境を創出する組成物および方法
US11051733B2 (en) * 2008-01-18 2021-07-06 Wake Forest University Health Sciences Isolating and purifying cells for therapy
US20130245757A1 (en) * 2011-11-04 2013-09-19 Allergan, Inc. Method and device for improved soft tissue surgery
EP2440652B1 (en) * 2009-06-11 2019-11-27 Minerva Biotechnologies Corporation Methods for culturing stem and progenitor cells
WO2011022070A2 (en) * 2009-08-20 2011-02-24 The Regents Of The University Of California Perivascular stem cell composition for bone
WO2011085301A1 (en) * 2010-01-08 2011-07-14 Baxter International Inc. Biomatrices to attract and retain regenerative and reparative cells
JP6196163B2 (ja) 2011-03-17 2017-09-13 ミネルバ バイオテクノロジーズ コーポレーション 多能性幹細胞を作製する方法
AU2012282660B2 (en) * 2011-07-11 2017-07-27 The Children's Hospital Of Philadelphia Oxidation resistant bioprosthetic tissues and preparation thereof
WO2013101720A1 (en) * 2011-12-28 2013-07-04 The Regents Of The University Of California Implantable vascular devices and methods of use thereof
US11028502B2 (en) * 2017-11-02 2021-06-08 Wake Forest University Health Sciences Vascular constructs
CN108187141A (zh) * 2018-01-31 2018-06-22 广州沙艾生物科技有限公司 一种心脏肌球衍生细胞在生物材料中的应用
CN110898254B (zh) * 2019-12-17 2021-11-30 浙江大学 一种用于修复子宫内膜并提高生育力的生物活性支架
GB2619893A (en) * 2021-03-23 2023-12-20 Terumo Bct Inc Cell capture and expansion

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6082364A (en) * 1997-12-15 2000-07-04 Musculoskeletal Development Enterprises, Llc Pluripotential bone marrow cell line and methods of using the same
CN1688607A (zh) * 2002-08-14 2005-10-26 阿维迪斯公司 包含支架,佐剂和抗原的异源多聚体化合物及其用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2153097T3 (es) 1995-04-07 2001-02-16 Mogens Havsteen Jakobsen Procedimiento de inmovilizacion fotoquimica de ligandos usando quinonas.
AU746325B2 (en) 1997-06-25 2002-04-18 Innogenetics N.V. Methods for covalent immobilisation of biomolecules to a carrier by means of a His-tag
DE19881727D2 (de) 1997-11-24 2001-01-04 Herbert P Jennissen Verfahren zur Immobilisierung von Mediatormolekülen auf anorganischen und metallischen Implantatmaterialien
AU2669599A (en) * 1998-02-12 1999-08-30 Regents Of The University Of California, The Compositions for receptor/liposome mediated transfection and methods of using same
JP2002527191A (ja) * 1998-10-20 2002-08-27 ティーイーアイ バイオサイエンシス インク 移植用心臓血管部品及びその製造方法
DE19904975A1 (de) 1999-02-06 2000-09-14 Impella Cardiotech Ag Vorrichtung zur intravasalen Herzklappenoperation
WO2001059455A2 (en) 2000-02-08 2001-08-16 Acspurt B.V. Immobilization of bioactive species
US6652583B2 (en) * 2000-04-07 2003-11-25 Rhode Island Hospital Cardiac valve replacement
US7524513B2 (en) * 2001-06-15 2009-04-28 Mao Hai-Quan Biofunctional fibers
AU2003286425A1 (en) * 2002-12-05 2004-06-23 Cardio Incorporated Layered bioresorbable implant
US20040126405A1 (en) * 2002-12-30 2004-07-01 Scimed Life Systems, Inc. Engineered scaffolds for promoting growth of cells
EP1611233B1 (en) * 2003-04-08 2016-01-06 Yeda Research And Development Co., Ltd. Stem cells having increased sensitivity to sdf-1 and methods of generating and using same
WO2005065079A2 (en) * 2003-11-10 2005-07-21 Angiotech International Ag Medical implants and fibrosis-inducing agents

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6082364A (en) * 1997-12-15 2000-07-04 Musculoskeletal Development Enterprises, Llc Pluripotential bone marrow cell line and methods of using the same
CN1688607A (zh) * 2002-08-14 2005-10-26 阿维迪斯公司 包含支架,佐剂和抗原的异源多聚体化合物及其用途

Also Published As

Publication number Publication date
JP4854670B2 (ja) 2012-01-18
DK2255834T3 (da) 2012-06-18
ATE471169T1 (de) 2010-07-15
ATE556728T1 (de) 2012-05-15
AU2005301111A1 (en) 2006-05-11
EP1812088A2 (en) 2007-08-01
GB0424560D0 (en) 2004-12-08
CA2582155A1 (en) 2006-05-11
JP2008518606A (ja) 2008-06-05
CN101094697A (zh) 2007-12-26
WO2006047841A3 (en) 2006-08-24
EP2255834A1 (en) 2010-12-01
PL2255834T3 (pl) 2012-09-28
DK1812088T3 (da) 2010-09-20
ES2347339T3 (es) 2010-10-28
ES2385785T3 (es) 2012-07-31
EP1812088B1 (en) 2010-06-16
EP2255834B1 (en) 2012-05-09
US20070264306A1 (en) 2007-11-15
AU2005301111B2 (en) 2011-11-17
WO2006047841A2 (en) 2006-05-11

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