CN101073594A - Method for producing platycodon Root lozenge in treatment of chronic pharyngitis - Google Patents
Method for producing platycodon Root lozenge in treatment of chronic pharyngitis Download PDFInfo
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- CN101073594A CN101073594A CN 200610080742 CN200610080742A CN101073594A CN 101073594 A CN101073594 A CN 101073594A CN 200610080742 CN200610080742 CN 200610080742 CN 200610080742 A CN200610080742 A CN 200610080742A CN 101073594 A CN101073594 A CN 101073594A
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- radix platycodonis
- buccal tablet
- radix
- active substance
- acid
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Abstract
The invention is concerned with a kind of Chinese traditional medicine for curing chronic pharyngolaryngitis, belonging to Chinese traditional medicine technology field, and producing it into oral tablet. Radix platycodonis and liquorice is Chinese traditional medicine playing the same roles. Produce tablet of radix platycodonis and clear away the heat-evil and expel superficial evils to relieve sore throat with acesodyne effect. It has good preventment and cure effect. Make the radix platycodonis soup into oral tablet with small dosage through modern technology to afford the active effect to cure patient. This invention has innovative signification in the Chinese traditional medicine field with wide future.
Description
1, technical field
The invention belongs to technical field of Chinese medicines, particularly relate to a kind of a kind of Chinese medicine for the treatment of chronic pharyngolaryngitis, and be made into oral buccal tablet.
2, background technology
Throat is one of vitals of human body, is diet and the intersection of breathing important channel, is first barrier of human body opposing pathogenic bacteria, virus.Throat disease can not get radical cure for a long time, easily causes tens of kinds of diseases that serious threat is healthy such as heart disease, pleuritis, nephritis, arthritis, bronchitis, laryngocarcinoma.
Along with The development in society and economy, the quickening of rhythm of life, the going from bad to worse of ecological environment, as industrial pollution, air pollution, chemical contamination etc., the pharyngitis sickness rate is with annual 1.7% speed increase.The sickness rate of China's pharyngitis is up to 87%.In the face of pharyngitis patient cumulative year after year and the serious harm that brings, and pharyngitis does not have efficient medicine in decades, this urgent day by day present situation, countries in the world government and WHO pay much attention to, successively drop into the seek treatment excellent medicine of throat disease of a large amount of manpowers and fund.The Chinese government also includes the treatment of throat disease in the medical research key subjects in 20th century, and posts hope new breakthrough is arranged in national medicine.
Radix Platycodonis, Radix Glycyrrhizae are integration of edible and medicinal herbs (Chinese medicine that can be used for keeping healthy) class Chinese crude drug, and Radix Platycodonis and Radix Glycyrrhizae are with using famous prescription---the Radix Platycodonis decoction that is in the Zhang Zhongjing " Treatise on Febrile and Miscellaneous Disease ".Through our discovering, Radix Platycodonis decoction is made buccal tablet, have tangible heat-clearing and toxic substances removing, the relieving sore throat and pain effect.The all cards of SHAO YIN syndrome pharyngalgia had good preventing and therapeutic effect.
Therefore, Radix Platycodonis decoction is studied by modern crafts, is made into to be buccal tablet, makes its taking dose little, easy to carry, and more can give full play to pharmaceutically active, thereby reaches the clinical treatment effect to patient.Therefore, the present invention has uniqueness and innovative significance in the Chinese medicine research field.Its application prospect is very wide.
3, summary of the invention
The Radix Platycodonis buccal tablet is to be found and invention through experimental study for many years by the scientific research personnel of China Academy Of Traditional Chinese Medicine Traditional Chinese Medicine Research Institute.Mainly consist of Radix Platycodonis, Radix Glycyrrhizae in the Radix Platycodonis buccal tablet, by relevant bibliographical information and we animal experiment of active component in the two flavor medicines is studied, and produced as a trial proof in repeatedly, the Radix Platycodonis buccal tablet has tangible reducing swelling and alleviating pain effect.
Main active substances in the Radix Platycodonis buccal tablet has: mainly contain multiple triterpenoid compound, flavone compound, Angelica Polysaccharide, aminoacid and trace element or the like.As glycyrrhizic acid, enoxolone, glycyrrhizin (Glycyrrhizin), Glycyrrhiza uralensis Fisch. saponin first, liquirtin (Liquiritin), Neoliquiritin (Neolliquiritin), glycyrrhizin (Liquiritigenin), platycodin A, B, C (platycodinA, B, C), platycodigenin (Platycodigenin), platycogenic acid A, B, C (Platycogenic acid, A, B, C), Polygalacic acid (Polygalacic acid), betulinol (Betulin), the bessisterol glucoside, aspartic acid, lysine or the like.
The structural formula of active substance:
Glycyrrhizic acid (Glycyrrhizic acid) enoxolone (Glycyrrhetinic acid)
Glycyrrhizin (Liquiritigenin) liquirtin (Liquiritin)
R
1 R
2
Betulinol (Betulin) platycodin A (platycodin A) H H
Platycodin B, (platycodin B) COOH H
Platycodoside C (platycodin C) H COCH
3
Polygalacic acid (Polygalacic acid)
4, description of drawings
5, the specific embodiment
The full presciption medicine material is pulverized mixing, adds 10 times of water gagings, and reflux 45 minutes is filtered.The medical material residue adds the water of 8 times of amounts again, and reflux 45 minutes is filtered.Merging filtrate is concentrated into small size, and drying under reduced pressure becomes powder.Add adjuvant, mixing.Compacting in flakes.
Claims (7)
1, the preparation technology of Radix Platycodonis buccal tablet is characterized in that existing in the buccal tablet active substance that extracts by a certain percentage with Radix Platycodonis, Radix Glycyrrhizae to add the oral buccal tablet agent that adjuvant is made, and this buccal tablet has the health-care effect to laryngopharynx swelling and pain.
2, it is 1: 0.5～1: 5 by claim 1 described use medical material Radix Platycodonis, Radix Glycyrrhizae usage ratio
3, be as extraction solvent with water or ethanol by the active substance of claim 1 described extraction.
4, the consumption by claim 3 described extraction solvent (water, ethanol) is 5～15 times.
5, the adjuvant ratio with adding in Radix Platycodonis, Radix Glycyrrhizae extraction active substance in the claim 1 described Radix Platycodonis buccal tablet is: 1: 1～1: 20.
6, Radix Platycodonis, the active substance that Radix Glycyrrhizae is extracted comprises: triterpenoid compound, flavone compound, Angelica Polysaccharide, aminoacid and trace element, as glycyrrhizic acid, enoxolone, glycyrrhizin (Glycyrrhizin), liquirtin (Liquiritin), Neoliquiritin (Neolliquiritin), glycyrrhizin (Liquiritigenin), platycodin A, B, C (platycodinA, B, C), platycodigenin (Platycodigenin), platycogenic acid A, B, C (Platycogenic acid, A, B, C), the bessisterol glucoside, aspartic acid, lysine.
7, has health-care effect by claim 1 described Radix Platycodonis buccal tablet to laryngopharynx swelling and pain.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610080742 CN101073594A (en) | 2006-05-16 | 2006-05-16 | Method for producing platycodon Root lozenge in treatment of chronic pharyngitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610080742 CN101073594A (en) | 2006-05-16 | 2006-05-16 | Method for producing platycodon Root lozenge in treatment of chronic pharyngitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101073594A true CN101073594A (en) | 2007-11-21 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200610080742 Pending CN101073594A (en) | 2006-05-16 | 2006-05-16 | Method for producing platycodon Root lozenge in treatment of chronic pharyngitis |
Country Status (1)
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| CN (1) | CN101073594A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103735894A (en) * | 2013-12-23 | 2014-04-23 | 广西博科药业有限公司 | Pharynx-clearing throat-refreshing lozenges and preparation method thereof |
| CN104666413A (en) * | 2015-03-11 | 2015-06-03 | 黄振忠 | Medicine for treating swollen sore throat |
| CN105943513A (en) * | 2016-06-20 | 2016-09-21 | 常熟求是科技有限公司 | Radix platycodonis throat lozenge and preparing method thereof |
| CN109106747A (en) * | 2018-07-02 | 2019-01-01 | 宁夏医科大学 | A kind of pharynx-clearing throat-benefiting buccal tablet and preparation method thereof |
| CN113521122A (en) * | 2021-06-29 | 2021-10-22 | 完美（广东）日用品有限公司 | Method for preparing solubilizing composition |
| CN114344404A (en) * | 2021-12-16 | 2022-04-15 | 江中食疗科技有限公司 | A composition with throat moistening effect and its preparation method |
| WO2023125798A1 (en) * | 2021-12-29 | 2023-07-06 | 湖南湘源美东医药科技有限公司 | Traditional chinese medicine composition and preparation method and application thereof |
-
2006
- 2006-05-16 CN CN 200610080742 patent/CN101073594A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103735894A (en) * | 2013-12-23 | 2014-04-23 | 广西博科药业有限公司 | Pharynx-clearing throat-refreshing lozenges and preparation method thereof |
| CN104666413A (en) * | 2015-03-11 | 2015-06-03 | 黄振忠 | Medicine for treating swollen sore throat |
| CN105943513A (en) * | 2016-06-20 | 2016-09-21 | 常熟求是科技有限公司 | Radix platycodonis throat lozenge and preparing method thereof |
| CN109106747A (en) * | 2018-07-02 | 2019-01-01 | 宁夏医科大学 | A kind of pharynx-clearing throat-benefiting buccal tablet and preparation method thereof |
| CN113521122A (en) * | 2021-06-29 | 2021-10-22 | 完美（广东）日用品有限公司 | Method for preparing solubilizing composition |
| CN114344404A (en) * | 2021-12-16 | 2022-04-15 | 江中食疗科技有限公司 | A composition with throat moistening effect and its preparation method |
| WO2023125798A1 (en) * | 2021-12-29 | 2023-07-06 | 湖南湘源美东医药科技有限公司 | Traditional chinese medicine composition and preparation method and application thereof |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20071121 |