CN101052867B - 用于流式细胞计数的多波长光的频率复用检测 - Google Patents

用于流式细胞计数的多波长光的频率复用检测 Download PDF

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Publication number
CN101052867B
CN101052867B CN2005800366981A CN200580036698A CN101052867B CN 101052867 B CN101052867 B CN 101052867B CN 2005800366981 A CN2005800366981 A CN 2005800366981A CN 200580036698 A CN200580036698 A CN 200580036698A CN 101052867 B CN101052867 B CN 101052867B
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light
detector array
wavelength
frequency
array
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Chinese (zh)
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CN101052867A (zh
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J·A·科克斯
D·J·祖克
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Honeywell International Inc
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Honeywell International Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/1438—Using two lasers in succession
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1477—Multiparameters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1486—Counting the particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/069—Supply of sources
    • G01N2201/0691—Modulated (not pulsed supply)

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  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN2005800366981A 2004-09-01 2005-09-01 用于流式细胞计数的多波长光的频率复用检测 Expired - Fee Related CN101052867B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/931,686 2004-09-01
US10/931,686 US7612871B2 (en) 2004-09-01 2004-09-01 Frequency-multiplexed detection of multiple wavelength light for flow cytometry
PCT/US2005/031493 WO2006026766A2 (en) 2004-09-01 2005-09-01 Frequency-multiplexed detection of multiple wavelength light for flow cytometry

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CN101052867A CN101052867A (zh) 2007-10-10
CN101052867B true CN101052867B (zh) 2012-05-02

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Country Link
US (1) US7612871B2 (enExample)
EP (1) EP1784630B1 (enExample)
JP (2) JP2008511843A (enExample)
CN (1) CN101052867B (enExample)
WO (1) WO2006026766A2 (enExample)

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CN101099082B (zh) 2004-12-03 2013-03-27 塞通诺米/St有限责任公司 用于粒子处理的整体式盒
US9260693B2 (en) 2004-12-03 2016-02-16 Cytonome/St, Llc Actuation of parallel microfluidic arrays
WO2012036794A2 (en) * 2010-08-01 2012-03-22 Array Optronix, Inc. Photodetectors with light incident surface and contact surface and applications thereof
CN102288531B (zh) * 2011-04-21 2012-12-19 西北工业大学 过滤染色计数细胞的方法及装置
ES2778148T3 (es) * 2018-01-31 2020-08-07 Sick Engineering Gmbh Aparato de análisis para la determinación de polvo fino
EP3933376A1 (en) * 2020-07-02 2022-01-05 Deutsches Rheuma-Forschungszentrum Berlin Method and system for characterizing particles using an angular detection in a flow cytometer
CN114152559A (zh) * 2021-12-13 2022-03-08 常州必达科生物科技有限公司 一种光斑的检测方法及检测装置
CN114324205A (zh) * 2021-12-16 2022-04-12 赛默飞世尔（上海）仪器有限公司 对样品进行光谱测定的方法、系统以及流式细胞仪
WO2023146623A1 (en) * 2022-01-28 2023-08-03 Becton, Dickinson And Company Methods for array binning flow cytometry data and systems for same
WO2024157903A1 (ja) * 2023-01-25 2024-08-02 シンクサイト株式会社 フローサイトメータ

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Publication number Publication date
WO2006026766A2 (en) 2006-03-09
US7612871B2 (en) 2009-11-03
EP1784630B1 (en) 2018-05-30
CN101052867A (zh) 2007-10-10
US20060051096A1 (en) 2006-03-09
WO2006026766A3 (en) 2006-06-01
JP5762720B2 (ja) 2015-08-12
EP1784630A2 (en) 2007-05-16
JP2008511843A (ja) 2008-04-17
JP2011059127A (ja) 2011-03-24

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