CN101023994A - Medicinal liquor for treating rheumatism and rheumatoid diseases - Google Patents

Abstract

The present invention relates to a medicated white liquor for effectively curing rheumatic disease and rheumatoid diseases. It is made up by soaking 10 Chinese medicinal materials of multibanded krait, scorpion, prepared aconite main tuber, prepared wild aconite tuber, lonicera flower and others in white liquor. Its effective rate is 95% and its cure rate is 80%.

Description

A kind of treatment rheumatism, rheumatoid medicated wine

Technical field

The present invention relates to field of traditional Chinese, particularly relate to a kind of treatment rheumatism, rheumatoid medicated wine.

Background technology

Rheumatism, rheumatoid are a kind of common clinical, frequently-occurring disease, and the motherland tradition traditional Chinese medical science is referred to as " arthromyodynia ", are because exopathogen invasion and attack human body impatency meridians such as wind, cold, wet, heat, due to QI-blood circulation is smooth." element is asked: the numbness opinion " points out: " its migratory BI-syndrome caused mainly by pathogenic wind, BI-syndrome caused mainly by pathogenic cold being called painful BI, dampness victor for numbness also." common rheumatism has: rheumatism, rheumatoid arthritis, cold rheumatoid joint pain, gout, ankylosing spondylitis, osteoporosis, hyperosteogeny, proliferative arthritis, scapulohumeral periarthritis, lupus erythematosus, puerperal exposure to wind, intractable lumbago and skelalgia, sciatica, sjogren syndrome etc., with muscles and bones, muscle, joint ache, the disease of main performances such as numb, joint stuffiness or arthroncus.This disease sickness rate height, easily outbreak repeatedly, but obstinate disease cardiac trigger and other internal organs pathological changes.According to the health ministry investigation statistics, annual because of rheumatism, rheumatoid, osteopathia, directly or indirectly death toll reaches 1,500,000 people approximately.At present, doctor trained in Western medicine is suited the remedy to the case for adopt of the treatment of this disease more, medicine I based on antibiotic, hormone, analgesic, its short run effect still can, but be difficult for radical cure, can develop immunity to drugs but take for a long time not only, also can produce such as untoward reaction such as gastrointestinal function damage, osteoporosis, endocrine regulation, nervous system disorders and cortin hyperfunctioning.

Summary of the invention

The present invention is directed to the defective in the above-mentioned field, according to theory of Chinese medical science, provide a kind of treatment rheumatism, rheumatoid medicated wine, its curative effect is fast, and taking convenience is cheap.

A kind of treatment rheumatism, rheumatoid medicated wine, its crude drug is formed and weight portion is:

Bungarus Parvus 1-2 part, Scorpio 10-25 part, Radix Aconiti Preparata 10-20 part, Radix Aconiti Kusnezoffii Preparata 10-20 part, Radix Clematidis 10-20 part, Herba Asari 10-20 part, Rhizoma Cibotii 10-25 part, Flos Lonicerae 10-25 part, Flos Carthami 10-25 part, Ramulus Cinnamomi 10-20 part.

Preferred weight part is: 2 parts of Bungarus Parvus, 20 parts of Scorpios, 15 parts of Radix Aconiti Preparatas, 15 parts of Radix Aconiti Kusnezoffii Preparatas, 15 parts of Radix Clematidis, 15 parts of Herba Asari, 20 parts of Rhizoma Cibotii, 20 parts of Flos Loniceraes, 20 parts on Flos Carthami, 15 parts of Ramulus Cinnamomi.

Can also contain Fructus Chaenomelis 10-20 part, Fructus Lycii 10-20 part, Radix Cyathulae 10-20 part, dried Rhizoma Homalomenae 10-20 part, Rhizoma Et Radix Notopterygii 10-20 part, Radix Angelicae Pubescentis 10-20 part.

Preferred weight part is: 15 parts of Fructus Chaenomeliss, 15 parts of Fructus Lycii, 15 parts of Radix Cyathulaes, 15 parts of dried Rhizoma Homalomenae, 15 parts of Rhizoma Et Radix Notopterygiis, 15 parts of Radix Angelicae Pubescentiss.

Also be added with white sugar.

Described wine is 50 degree Chinese liquor, and the weight ratio of crude drug and 50 degree Chinese liquor is 1: 3-10, the weight ratio of white sugar and 50 degree Chinese liquor is 1: 2.

The present invention is according to the Chinese medicine and pharmacy principle, the method that adopts the collateral dredging that dries to invigorate blood circulation, and selected following a few flavor Chinese herbal medicine with the form of medicated wine, make treatment rheumatism, rheumatoid medicine.

1. Bungarus Parvus " decoction pieces is newly joined "

Have another name called: Agkistrodon, money Agkistrodon, Bungarus Parvus.

Base is former: for Agkistrodon halys section animal Agkistrodon or Elapidae animal Agkistrodon snakelet etc. is removed all of internal organs.

Composition: contain the thrombin-like material in the poisonous snake, esterase and 3 kinds of anticoagulative substances.The thrombin-like material is a kind of glycoprotein (containing 13% sugar), and molecular weight is about 3500.

Pharmacology: the thrombin-like material mainly is present in Viperidae (the comprising Agkistrodon) snake venom, these thrombin-like materials and thrombin are different, its procoagulant activity is not by effects of heparin, and it also is not quite similar with thrombin to fibrinogenic model of action, very unstable by the formed fibrin gel of thrombin-like material, easily dissolved, so that in human body, can cause hypofibrinogenemia, blood occurs and lose with fixed attention by the fibrinolysin in the blood.The anticoagulative substance effect: comprise antithromboplastic effect and fibrinolysis, agkistrodon halyx pallas venom, agkistrodon acutus venom have this two kinds of effects, also contain the material of antithromboplastic effect in the Ophiophagus hannah (Cantor)., thereby anticoagulant occurs.The two often exists coagulant and anticoagulant component simultaneously, sees Viperinae, Crotalinae, and some snake venom in the Elapidae as adder, all has these components in Agkistrodon and the king cobra venom.

Nature and flavor: sweet salty, temperature, poisonous.

Gui Jing: go into the liver spleen channel.

Function cures mainly:wind-damp dispelling, saturating muscles and bones Dings Jing .The dispelling the wind and dampness pathogens paralysis, arthralgia, leprosy, mange, a little less than infantile convulsion is jerked, tetanus, syphilitic skin lesion, scrofula malignant boil.

Compatibility and incompatibility of drugs: the interior-heat caused by deficiency of YIN person avoids clothes.

2. Scorpio: " another name for Sichuan Province book on Chinese herbal medicine "

Different name: a kind of scorpion's (" Book of Songs "), a kind of scorpion's tail worm (" saying literary composition "), Du's one hundred (" another name for Sichuan Province book on Chinese herbal medicine "), Scorpio (" Chinese medicine shape sex experience differential method "), Fu carries on the back worm (" Shanxi Chinese medicinal herbal ").

Base is former: be the dry Scorpio of Carnis Arca inflata scorpion section animal Carnis Arca inflata scorpion.

Composition: containing scorpion venom (Katsutoxin), is the Neurotoxic protein of a kind of similar snake venom.In addition, and contain trimethylamine, betanin, taurine, palmitic acid, stearic acid, cholesterol, lecithin and amine salt etc.

Pharmacology: 1. anticonvulsant action: the oral Zhijing San of mice, every day 1, gram serve on 1,3, to leptazol, the convulsions that strychnine and nicotine cause has antagonism after 9 days, and the effect that the antagonism strychnine is fainted from fear is the most remarkable, nicotine takes second place, and the leptazol effect is poorer, and cocaine does not then have.2. to the cardiovascular effect, intravenous injection Scorpio preserved material and decoct all can make rabbit, the momentary decline of dog blood pressure (minority can temporarily rise), but very fast recovery, persistent blood pressure drops then appears, keep more than 1-3 hour, decompression principle is for suppressing vasomotor center, blood vessel dilating, directly suppress heart and to adrenolytic boosting, clear-headed animal also there is obvious sedation, but animal is fallen asleep, also may be relevant with blood pressure lowering.Toxicity: scorpion venom (Buthotoxin, original name Katsutoxin) mainly act as and make respiratory paralysis, its minimum lethal dose is 0.07 milligram/kilogram to rabbit, and mice is 0.5 milligram/kilogram, the frog is 0.7 milligram/kilogram, the rabbit poisoning symptom is the orthocolosis spasm, sialorrhea, respiratory arrest, and increased blood pressure, the frog is extremity fibroid spasm then, and mice is extremity and respiratory paralysis after excitatory state then, and scorpion venom does not have blood coagulation and haemolysis.Isolated frog heart there is inhibitory action, frog hind leg blood vessel is had contraction, isolated rabbit intestinal and bladder are excitement.

Nature and flavor: salty, suffering, flat, poisonous.

Gui Jing: " detailed outline " meridian of Foot-JUE YIN.

Function cures mainly: dispel the wind relieving convulsion, collateral dredging, detoxifcation.Control convulsion with spasms, epilepsy, apoplexy, hemiplegia, facial hemiparalysis, migraine, rheumatic arthralgia, tetanus, lymphoid tuberculosis, the rubella skin ulcer is swollen.

3. Radix Aconiti Preparata is the process of preparing Chinese medicine decoction pieces of Radix Aconiti.

Radix Aconiti: Radix Aconiti has another name called Radix Aconiti " Medical Treasures of the Golden Chamber "

Base is former: be ranunculaceae plant Aconitum carmichjaelii Debx. (tuber of cultivation product).

Composition: contain 6 kinds of alkaloids: hypaconitine, aconitine, mesaconitine, talaisamine, chuan-wu base A and chuan-wu base B.Other says and contains hypaconitine in the tuber, aconitine, and mesaconitine, Ka Michalin etc., chuan-wu base B are exactly Ka Michalin.

Pharmacology: 1. to action of the heart: aconitine is to exsomatizing and the frog heart on the throne, just makes decreased heart rate (Ah taking off's product capable of blocking it) immediately owing to highly stimulated cardiac muscle, heart rate quickening suddenly, heart contractility is strengthened, occur the heart rate disorder very soon, heart contractility weakens, and final heart beating stops.Its therapeutic dose can make decreased heart rate to the people, pulse soft and a little less than, blood pressure edges down; Toxic dose can make the dog tachycardia, and property Fibrillation in chamber is fluttered.It is to action of the heart, part is owing to vagal influence, and main is direct effect to cardiac muscle, and (1) causes the effect of quivering: aconitine is poisoned and is very easily produced ventricular fibrillation, aconitine cause the effect of quivering, many at present instruments as the anti-arrhythmia of research.(2) cardiac stimulant effect: itself there is no cardiotonic aconitine, and is extremely strong to cardiac toxicity; And its hydrolyzate---the toxicity of aconine only is the 1/2000-1/4000 of aconitine.Meaning tool cardiotonic is arranged, can resist the arrhythmia that aconitine causes at isolated frog heart; In recent years there is human to test in isolated heart (frog, Cavia porcellus), faint cardiotonic is only arranged through the aconitine solution of hydrolysis in 10 and a half hours.

2. to the influence of blood pressure blood vessel: aconitine can make blood pressure drops, and Chinese Aconitum carmichjaelii Debx. and river Radix Aconiti Lateralis Preparata (RADIX ACONITILATERALIS PREPARATA) decoct can cause rapid and of short duration blood pressure lowering to anesthetized dog or cat.This moment, heart there is no significant change, and blood pressure lowering can be eliminated by a large amount of atropine or diphenhydramine.Show that with the peripheral resistance determinator RADIX ACONITILATERALIS PREPARATA decoct can cause that lower limb vascular significantly expands, still can expand coronary vasodilator (irrelevant) in addition, meaning emergency treatment for reviving YANG soup (Radix Aconiti Lateralis Preparata, Camphora, Radix Ginseng, Moschus) is arranged, boosting is arranged the blood pressure heart rate.

3. antiinflammation and with adrenocortical relation: the RADIX ACONITILATERALIS PREPARATA decoct has a tangible antiinflammation through lumbar injection or oral PARA FORMALDEHYDE PRILLS(91,95) and Ovum Gallus domesticus album ankle joint are swollen.RADIX ACONITILATERALIS PREPARATA decoct oral no matter (0.2 gram/100 grams), subcutaneous or intramuscular injection all can significantly reduce content of ascorbic acid in the rat adrenal gland, and its effect is not blocked by pentobarbital sodium and chlorpromazine, but can part be blocked by cortisone.

4. to central nervous system's influence: aconitine 0.1-0.2 milligram/kilogram, can destroy rat point defense-motion pole-climbing trained reflex, unconditioned reflex also is subjected to light damage, and each ammonia content of brain all sharply descends; Inject the rabbit ventriculus quartus with 0.002 microgram/kilogram, can cause the anesthesia phenomenon.

5. other effects: aconitine can suppress respiratory center, makes breathing slack-off; Excited earlier to the Mucocutaneous sensory nerve ending in part, to scratch where it itches, burn feeling continues with paralysis, but unconsciousness and reflexive cause that salivation is hyperfunction, and heating and intact animal's body temperature are reduced.

Toxicity: Aconitum carmichjaelii Debx. toxicity is extremely strong; because of the kind acquisition time; concoct; differences such as decocting time; the toxicity difference is very big, and alkaloid can lose 81.3% in the concocting process, and different regions Radix Aconiti Lateralis Preparata toxicity test can differ 8 times more than; do not have parallel relation between its total alkaloid content and toxicity intensity, and bigger relation is arranged with acetyl content.Tired hungry, hemorrhage animal toxicity can weaken, and sympathetic nervous system superfunction person easily poison.

Toxic dose: Radix Aconiti 0.1-3 two, Radix Aconiti Lateralis Preparata 0.5-2 two, oral 0.2 milligram of aconitine.Poisoning symptom: sialorrhea, feel sick vomiting, diarrhoea, giddy, dim eyesight, dispute, extremity and whole body are numb, and pulse reduces, dyspnea, tetany, unconsciousness, gatism, blood pressure and body temperature descend, and premature ventricular beat is that premature ventricular beat or sinus rhythm accompany by the frequent premature ventricular beat of multi-source and antrum stops fighting.Zoopery proves that the ECG change when RADIX ACONITILATERALIS PREPARATA is poisoned is similar to aconitine, and a large amount of atropine are to the rabbit of RADIX ACONITILATERALIS PREPARATA poisoning, and the electrocardiogram of Cavia porcellus has the improvement effect, but can not prevent animal dead, but has report can reduce mortality rate to the mice of aconite poisoning.Lignocaine can significantly reduce the mortality rate of animal because of aconite poisoning.Rhizoma Zingiberis Radix Glycyrrhizae and RADIX ACONITILATERALIS PREPARATA can make latter's toxicity reduce greatly with boiling, Flos Lonicerae in addition, and Semen phaseoli radiati, Cornu rhinocerotis also can detoxify.Aconitine is at the caused Fibrillation of isolated atria, procaine, and antihistaminic, the quinine fourth, heart Dean all can suppress it.

Nature and flavor: hot, heat, poisonous.

Gui Jing: 1. " key medicine is divided agent ", go into spleen, the gate of vitality's two warps.2. herbal summary " the moon of fainting of starting with.Shaoyin channel.”

Function cures mainly: dispelling cold and dampness, the ailment said due to cold or exposure of loosing, wet warp, pain relieving.Control anemofrigid-damp arthralgia, severe and migratory arthralgia pain, spasm of the limbs, hemiplegia, wind syndrome of head headache, trusted subordinate's cold type of pain, carbuncle of yin nature toxic swelling.

Compatibility and incompatibility of drugs: the deficiency of YIN excess of YANG, heat symptom-complex pain and not being taken by pregnant women.

4. Radix Aconiti Kusnezoffii Preparata is the process of preparing Chinese medicine decoction pieces of Radix Aconiti Kusnezoffii.

Radix Aconiti Kusnezoffii (Radix Aconiti Kusnezoffii, Hou Ningji " medicine spectrum ")

Different name: violet (" village "), splendid achnatherum (" elegant "), Aconitum carmichjaelii Debx., black beak, why poison (" book on Chinese herbal medicine "), chicken poison (" Huainan "), gelsemium, eternal lasting, poison is public, fruit is negative, Geng Zi, Supreme Being's autumn (" WU Pu Bencao "), Radix Aconiti Kusnezoffii grass (" continuous Chinese book "), Odontobutis obscura (T. Et S.) (" Japan hanako materia medica "), Radix Aconiti Kusnezoffii (" Shengji Zonglu "), ring Aconitum carmichjaelii Debx., golden crow (" detailed outline "), Gelsemium elegans Benth. (" Xinjiang medical material ").

Base is former: be the tuber of ranunculaceae plant Aconitum carmichjaelii Debx. (wild species), Aconitum kusnezoffii Reichb or other multiple congeners.

Composition: Aconitum carmichjaelii Debx. Aconieum chinese each several part contains alkaloid, wherein is mainly aconitine (Aconitine), generates aconine (Aconine) acetic acid and benzoic acid after the aconitine hydrolysis.

Aconitum Karadkolicum Rap. contains aconitine, songorine, songoramine, karacoline, karacolidine, aconifine.Accurate Ge Er aconite root total alkaloids amount 1.5% is mainly aconitine, and songorine, aerial parts contain total alkaloids amount 0.7%, are mainly songorine.Aconitine contained alkaloid in Yadong is pseudo-aconitine.

Pharmacology: Radix Aconiti Kusnezoffii (kind is not identified) has stronger analgesic activity with woolfe-Macdonald method test, as with the Radix Gentianae Macrophyllae compatibility, its analgesia is renderd a service and can be strengthened mutually.Radix Aconiti Kusnezoffii is after Radix Glycyrrhizae, Semen sojae atricolor are concocted, and toxicity reduces and do not influence its analgesia and render a service.Radix Glycyrrhizae, Mel have Detoxication to Radix Aconiti Kusnezoffii.The effect of Radix Aconiti Kusnezoffii and Radix Aconiti is basic identical, the former alkaloid 0.425%, and the latter 0.599%.

The total alkali that proposes in the Aconitum Karadkolicum Rap., 10-20 milligram/kilogram is injected in anesthetized dog and rabbit, and visible heart beating irritability and conduction get muddled from the electrocardiogram.

The alkaloid that proposes in the autocollimatic Ge Er aconite root surpasses more than 30 kinds, songorine belongs to Atisine one class, with its 400mg/ kilogram subcutaneous injection, can make the white mice spontaneous activity reduce the tetanic property of hind leg contraction sometimes, rabbit there is weak sedation, and can prolong mice with the anesthesia duration that hypnotic causes, being used for rabbit has cooling effect, but the intravenous injection blood pressure lowering, heavy dose of can block nerves saving has the weak M-choline-like effect of separating.The tincture external can be used as analgesic, with the treatment neuralgia, and migraine etc., its analgesic effect mainly comes from aconitine, and toxicity is very big.

Nature and flavor: suffering, heat, poisonous.

Gui Jing: go into liver, spleen, lung meridian.

Function cures mainly: search wind prevailing over dampness, dispersing cold for relieving pain is opened expectorant, detumescence.Control anemofrigid-damp arthralgia, paralysis due to windstroke, tetanus, wind syndrome of head, coldness and pain in the epigastrium, accumulation of phlegm in the hypochondrium, air parcel, cold-dysentery, sore throat, furuncle, scrofula.

Compatibility and incompatibility of drugs: all empty people, anemia of pregnant woman, hyperactivity of fire caused by deficiency of YIN and heat syndrome pain person avoid clothes, the careful usefulness of survivor.

5. Radix Clematidis (wait peaceful collection " medicine spectrum ")

Different name: can disappear (" Kaibao Bencao "), hide Radix Clematidis (" Shen Liangfang of Soviet Union "), Wei Siberian cocklebur celestial being (" Margarita is assisted "), radix smilacis sieboldi's (" detailed outline "), Radix Clematidis (" medicine justice ", black foot Radix Clematidis (" the SHENGCAO property of medicine is wanted fully "), nine careless rank, windmill (" modern practical Chinese medicine ").

Base is former: be the root of ranunculaceae plant Radix Clematidis.Congener is done still having of Radix Clematidis use: 1. the mountain knotweed has another name called: narrow leaf Radix clematidis floridae, black common vetch.2. Herba Clematidis Lasiandrae, 3. post fruit Radix clematidis floridae has another name called: tiger teacher rattan, 4. meyer clematis, 5. henry clematis, 6. Caulis Clematidis Finetianae, 7. northeast clematis, 8. Rhizoma Dioscoreae Bulbiferae.

Composition: the root of Radix Clematidis contains Anemonin (Anemonin), anemonol (Anemonol), sterol, saccharide, Saponin, lactone, phenols, aminoacid.Leaf contains lactone, phenols, triterpene, aminoacid, organic acid.

[composition] 1. the root of Radix Clematidis contains Anemonin, anemonol, sterol, saccharide, Saponin, lactone, phenols, aminoacid.Leaf contains lactone, phenols, triterpene, aminoacid, organic acid.2. the leaf of mountain knotweed contains flavonoids such as Coumarins 0.82%, nimbecetin 0.23% and alkaloid, volatile oil, resin etc., do not contain Saponin, tannin or heart tonifying glycoside 3. the root of northeast clematis contain triterpenoid saponin: clematitol A, clematitol A ', clematitol B, clematitol C.4. the root of Rhizoma Dioscoreae Bulbiferae and mutation thereof contains Saponin, hederagenin.

Pharmacology: 1. to the effect of blood circulation: narrow leaf Radix clematidis floridae (being the mountain knotweed) 50% preserved material, can make the blood pressure drops of anesthetized dog, the stomach volume dwindles, and its decoct drug effect only reaches preserved material half.Stripped Bufo siccus heart is had the effect that suppresses the back excitement earlier, and seemingly than the big approximately 3-5 of decoct doubly, its hypotensive effect may be relevant with the inhibition of heart for the drug effect of its preserved material.2. to the influence of smooth muscle: narrow leaf Radix clematidis floridae decoct has tangible excitation to the mice intestine in vitro, may be the direct effect to smooth muscle, and the intestine in vitro of rat and rabbit is also had similar action.3. antidiuretic activity: narrow leaf Radix clematidis floridae preparation is to mice, and Cavia porcellus has tangible antidiuretic activity.This effect, preserved material and decoct are about equally.4. hypoglycemic activity: the Radix Clematidis preserved material has the effect (after promptly giving rat with a large amount of glucoses, the glucose in urine test is still negative) of obvious enhancing glucose assimilation to normal rat, so may have hypoglycemic activity.5. other effects: Radix Clematidis decoct 0.025 gram/10g (1/8 minimum lethal dose), lumbar injection can slightly improve mice pain valve (hot plate method), so have analgesia usefulness.

Nature and flavor: hot salty, temperature, poisonous.

Gui Jing: go into urinary bladder channel.

Function cures mainly: wind-damp dispelling, the meridian dredging, expectorant saliva, the hypochondriac lump of loosing.Control gout, insensitive impediment, chills and pain of the waist and kness, malaria ， lumps in the chest and abdomen, tetanus, tonsillitis, all a fishbone or other bone caught in the throat pharynxs.

Compatibility and incompatibility of drugs: a little less than the deficiency of vital energy blood, calm raw damp person avoids clothes.

6. Herba Asari " herbal classic "

Different name: Xiao Xin (" herbal classic "), Herba Ceratophylli Demeersi (" WU Pu Bencao "), few hot (" detailed outline "), Kingdonia uniflora, Jin Pencao (" the Chinese crude drug handbook), recluse join (Jiangsu).

Base is former: be the whole herb with root of aristolochiaceae plant Herba Asari or magnificent Herba Asari.

Composition: Herba Asari contains that volatile oil is about 3%, and main component of essential oil is a methyleugenol, and other has safrole nopinene, Eucarvone, phenolic substance etc.China's Herba Asari contains volatile oil 2.75%.Main Ingredients and Appearance is methyleugenol (accounting for 50%) in the volatile oil, also has saishinone, pinene, Eucarvone, safrole, 1,8-cineole (accounting for 0.2%) etc.The mutation A.sicboldii var.seoulensis Nakai of China's Herba Asari is similar with magnificent Herba Asari with A.sieboldii var cineoliferum volatile oil composition.

Pharmacology: 1. local anesthesia effect: magnificent Herba Asari water logging agent or pure preserved material (20-100%) can be blocked the sciatic conduction of impulse of the frog, in the test of Cavia porcellus skin mound, have infiltration anesthesia to render a service, but decoct are invalid.Herba Asari volatile oil still has topical anesthesia (rabbit corneal reflection) effect, and 50% Herba Asari tincture is made an appointment with half a minute after being applied to people's tongue, and the tip of the tongue promptly has hot creeping chill, after 1 minute feeling of numbness is arranged, later pain sensation complete obiteration, and the beginning recovers gradually through about 1 hour.Local action is contained that volatile oil is relevant with it, but stronger zest is arranged, and still discomfort is done the topical anesthesia agent.Report is arranged, and Herba Asari and other Chinese medicine share, and smear anesthesia with exodontia, obtain better effects.

2. analgesic, analgesic activity: that milliliter/kilogram gives rabbit to the arabic gum Emulsion 0.2-1.0 of Herba Asari volatile oil is oral, and the fervescence that normal and Wen Cifa are caused all has the reduction effect.To the heating that tetrahydro-beta-naphthyl-amine or typhoid fever, paratyphoid fever mixed vaccine cause, 0.5 milliliter/kilogram of oral volatile oil is some inhibitory action also.Same dosage has analgesic activity to rabbit (electricity irritation tooth marrow method), and intensity is similar to anodynine.

3. bacteriostasis: preliminary in vitro tests, Herba Asari be to Hemolytic streptococcus, dysentery bacterium, Bacillus typhi, so tubercule bacillus some inhibitory action is arranged, remain further research.

4. to the effect of blood pressure: magnificent Herba Asari leachate (0.125-0.25 gram/kilogram) intravenous injection, can reduce the blood pressure of anesthetized dog.Further analyze and point out; Basin grass Herba Asari volatile oil can make the anesthetized animal blood pressure drops, and decoct then makes increased blood pressure, and calls magnificent Herba Asari instant embrane and blood pressure are all had the effect of epinephrine sample.

5. toxicity and other effects: magnificent Herba Asari volatile oil is to the frog, mice, rabbit etc., just be excited phenomenon, then sink into palsy, voluntary movement and respiratory movement are gone down, the while areflexia, dead with respiratory paralysis eventually, breathing stops prior to heart beating, and myocardium smooth muscle is had direct repression.Alcohol extract on one's body rabbit, can antagonism the respiration inhibition that causes of morphine.To mouse stomach and intravenous injection, its median lethal dose(LD 50) is respectively 123.75 milligrams and 7.78 milligrams/10 grams.The toxicity of kakuol leachate is greater than water decoction.

Nature and flavor: hot, warm.

Function cures mainly: dispels the wind, and cold expelling, row water is had one's ideas straightened out.Control the cold wind headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatism paralysis.Compatibility and incompatibility of drugs: deficiency of vital energy hyperhidrosis, the blood deficiency headache, clothes are avoided in coughs due to yin deficiency etc.

7. Rhizoma Cibotii (" herbal classic ")

Different name: Rhizoma Cibotii (" herbal classic "), Canis familiaris L. green grass or young crops, strong backbone (" WU Pu Bencao ") is held up lid, holds up muscle (" not record "), just ridge (Collective Notes to the Canon of Materia medica).

Base is former: be Dicksoniaceae plant all woolen Canis familiaris L. rhizome.

Composition: Rhizoma Cibotii rhizome starch-containing about 30%.The Rhizoma Osmundae rhizome is starch-containing up to 48%, and contains the tannin class.

Nature and flavor: bitter sweet, temperature.

Gui Jing: go into liver, kidney channel.

Function cures mainly: invigorating the liver and kidney, remove rheumatism, strong waist foot, sharp joint.Control the back ache, the gonalgia flaccidity of the lower limbs, cold-damp general arthralgia loses and drowns, frequent micturition, seminal emission, leucorrhea.

Compatibility and incompatibility of drugs: the deficiency of YIN has heat, the careful clothes of dysuria person.

8. Flos Lonicerae: (" carrying out the rock book on Chinese herbal medicine ")

Different name: Flos Lonicerae (Tang Materia Medica), Flos Lonicerae (" Wenbing Tiaobian, Detailed Analysis of Epidemic Warm Diseases ") Flos Lonicerae (" the Chinese crude drug handbook), Flos Lonicerae (" Shaanxi Chinese medicinal herbal ").

Base is former: be the caprifoliaceae plant alabastrum of Radix Ophiopogonis.

Composition: contain luteolin, inositol about 1% and Saponin, tannin etc.

Pharmacology: 1. antibacterial action: external to various bacteria (Bacillus typhi, Salmonella paratyphi, escherichia coli, Bacillus proteus, bacillus pyocyaneus, bordetella pertussis, vibrio cholera and staphylococcus, streptococcus, Diplococcus pneumoniae, meningococcus etc.) inhibitory action all arranged.Flos Lonicerae has some inhibitory action external to the Bacillus tuberculosis.2. other effects: obey a large amount of cholesterol for the fasting rat, as obeying Flos Lonicerae 2.5 gram/kilograms simultaneously, then the blood cholesterol level is low than matched group, so Flos Lonicerae can reduce intestinal to cholesteric absorption.

Nature and flavor: sweet, cold.

Gui Jing: go into lung, the stomach warp.

Function cures mainly: heat clearing away, detoxifcation.Control the epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, scrofula, anal fistula.

Compatibility and incompatibility of drugs: Deficiency and coldness of spleen and stomach and deficiency of vital energy skin infection pus-serum person avoid clothes.

9. Flos Carthami (" Bencao Tujing ")

Different name: red blue flower (" Medical Treasures of the Golden Chamber "), thorn Flos Carthami (" Sichuan Chinese medicinal herbal "), Flos Carthami (" Shaanxi Chinese medicinal herbal ").

Base is former: be the flower of feverfew Flos Carthami.

Composition: Flos Carthami contains Carthamus yellow (safflor yellow) and carthamin (carthamin).Carthamin gets glucose and Flos Carthami element through hydrochloric acid hydrolysis.Also contain 15 α, 20 beta-dihydroxies-Δ ⁴-pregnene-3-ketone.Still fatty in addition oil claims safflower oil, is Palmic acid, stearic acid, and arachidic acid, oleic acid, linoleic acid, linolenic acid etc. get glycerolipid.

Pharmacology: 1. to the effect in uterus: decoct is to mice, Cavia porcellus, and rabbit, dog, cat is exsomatizes, uterus on the throne and rabbit fistula of uterus all have excitation, but is weaker than the Stigma Croci decoct.2. to the effect of blood circulation: decoct is similar to the Stigma Croci decoct, and anesthetized animal is had blood pressure lowering, suppresses effects such as heart.On the isolated rabbit ear preparation, pressor effect is arranged.3. other effects: to the rabbit of hypercholesterolemia, oral safflower oil 1 gram/kilogram/day can reduce total cholesterol in the serum, total fat, the level of glyceryl trinitrate and non-esterified fatty acid.

Nature and flavor: suffering, temperature.

Gui Jing: go into the heart, Liver Channel.

Function cures mainly: promoting blood circulation to restore menstrual flow, go the pain relieving of becoming silted up.Control amenorrhea ， mass in the abdomen, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis is had a pain, carbuncle, traumatic injury.

Compatibility and incompatibility of drugs: be not taken by pregnant women.

10. Ramulus Cinnamomi (Tang Materia Medica)

Different name: Liu Gui (" book on Chinese herbal medicine is not mentionleted alone ")

Base is former: be the twig of canella Cortex Cinnamomi cinnamomum cassia presl.

Pharmacology: 1. antibacterial action: the Ramulus Cinnamomi alcohol extract can suppress escherichia coli external, bacillus subtilis and staphylococcus aureus, and valid density is 25 mg/ml or following; To Staphylococcus albus, dysentery bacterium, typhoid fever and paratyphoid fever bacillus, streptococcus pneumoniae, aerobacteria, Bacillus proteus, anthrax bacillus, vibrio cholera etc. also have inhibitory action.2. antivirus action: cultivate with human embryo kidney (HEK) monolayer upper strata of former generation cell tissue, Ramulus Cinnamomi decoct (1: 20) has inhibitory action to the first type capital 68-1 of section strain of influenza Asia and Orphan virus.3. diuresis: give the anesthetized dog intravenous injection with the WULING SAN 0.25 gram/kilogram that contains Ramulus Cinnamomi, dog urine amount is increased, singly annotate (0.029 gram/kilogram) diuresis with the Ramulus Cinnamomi vein and use remarkable than other four prescriptions.

Nature and flavor: Xin Gan, temperature.

Gui Jing: go into bladder, the heart, lung meridian.

Function cures mainly: diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation.Control exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention, amenorrhea and mass in the abdomen.

Compatibility and incompatibility of drugs: the card of the epidemic febrile disease and the deficiency of YIN excess of YANG, blood disorder is not taken by pregnant women.

11. Fructus Chaenomelis (" Thunder God big gun moxibustion opinion ")

Different name: Fructus Chaenomelis real (" not Lu "), iron pin pear (" clear different record ")

Base is former: be the fruit of rosaceous plant chaenomeles lagenaria.

Composition: contain Saponin, malic acid, tartaric acid, citric acid, vitamin C, flavonoid, tannin.

Nature and flavor: acid, temperature.

Gui Jing: go into liver, spleen channel.

Function cures mainly: suppressing the hyperactive liver and easing the stomach, Shujin dries.Control the convulsion of vomiting and diarrhoea, arthralgia chiefly caused by damp pathogen, beriberi, edema, dysentery.

12. Fructus Lycii (" not Lu ")

Different name: Gou Qizi (Collective Notes to the Canon of Materia medica), FRUCTUS LYCII (" Hebei medical material "), Fructus Lycii (" hiding mansion medicine formula revisal ")

Base is former: be the mature fruit of matrimony vine of solanaceae plant or lycium barbarum.

Composition: contain 3.39 milligrams of % of carotene in the Fructus Lycii, 0.23 milligram of % of thiamine; 0.33 milligram of % of riboflavin, 1.7 milligrams of % of Yan acid, 3 milligrams of % of ascorbic acid.

Pharmacology: 1. lipotropy: the infusion (20% of Lycium barbarum L., 8ml/ days), to mice by the carbon tetrachloride infringement, there is slight inhibition fat in hepatocyte, to deposit, promote hepatocyte new life's effect, the lipotropic effect of water extract also shows, prevents the liver dysfunction that carbon tetrachloride causes.2. intend the choline-like effect: the intravenous injection of Fructus Lycii water extract, can cause that rabbits blood pressure reduces, breathe excited; Atropine or cut-out vagus nerve can suppress this reaction.

Nature and flavor: sweet, flat.

Gui Jing: go into liver, kidney channel.

Function cures mainly: nourishing kidney; Lung moistening, tonifying liver makes eye bright.The treating the liver kidney yin is lost, and soreness of the waist and knees is had a dizzy spell, the many tears of blurred vision, and cough due to consumptive disease is quenched one's thirst, seminal emission.

Compatibility and incompatibility of drugs: the exopathogen excess-heat, insufficiency of the spleen have wet and the person of having loose bowels avoids clothes.

13. Radix Cyathulae (" medical material compilation of data ")

Base is former: be the root of amaranthaceous plant Radix Cyathulae or headdress flower anthracene grass.

Composition: root contains alkaloid, also isolates multiple C29 insectean metamorphosis steroidal in the root; Cyasterone, capitasterone, amaransterone A, amaransterone B, sengosteron, precyaterone, isocysterone.Isolate a kind of C21 steroidal poststerone in addition.

Nature and flavor: (" Sichuan Chinese medicinal herbal "): " property is flat, and sweet and slightly bitter taste is nontoxic.”

Gui Jing: (" Sichuan Chinese medicinal herbal "): " going into sweet kidney " two warps.

Function cures mainly: dispel the wind, dampness removing stimulates the menstrual flow, and invigorates blood circulation.The dispelling the wind and dampness pathogens lumbocrural pain, foot flaccidity clonic spasm of the muscle, stranguria with blood hematuria, women's blood Bi ， mass in the abdomen.

Compatibility and incompatibility of drugs: (" Sichuan Chinese medicinal herbal "): " women's menorrhagia, gestation, the emission person avoids clothes.”

14. Rhizoma Homalomenae (" detailed outline is picked up any lost article from the road ")

Different name: Rhizoma Homalomenae (" Chinese medicinal herbal "), Rhizoma Homalomenae (" medical material compilation of data ")

Base is former: be aroid Rhizoma Homalomenae rhizome.

Composition: contain armaticity volatilization wet goods.

Nature and flavor: suffering, temperature.

Gui Jing: go into liver, kidney, lung meridian.

Function cures mainly: wind-damp dispelling, strengthening bone and muscle, pain relieving, detumescence.The dispelling the wind and dampness pathogens arthralgia pain, podomere is ached, and the muscles and bones flaccidity is soft, stomachache, the carbuncle skin ulcer is swollen.

Compatibility and incompatibility of drugs: avoid Radix Raphani.

15. Rhizoma Et Radix Notopterygii (" herbal classic ")

Different name: Qiang green grass or young crops, protect the envoy of Qiang (" herbal classic "), Hu king envoy's (" WU Pu Bencao "), wind envoy (" pharmacologys of traditional Chinese medicines ") moves back in Qiang's sliding (" book on Chinese herbal medicine covers bamboo fish trap ")

Base is former: be umbrella section plant Rhizoma Et Radix Notopterygii, the root and rhizome of Radix et Rhizoma Notopterygii or angelica.

Composition: Radix et Rhizoma Notopterygii contains the volatilization wet goods.

Nature and flavor: hot, bitter, warm.

Gui Jing: go into kidney, urinary bladder channel.

Function cures mainly: the exterior cold of loosing, wind-damp dispelling, sharp joint.The wind and cold that cures cold, it is lossless to have a headache, anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema, skin sore.

Compatibility and incompatibility of drugs: the blood deficiency arthralgia pain is avoided clothes.

16. Radix Angelicae Pubescentis (" herbal classic ")

Different name: solely shake grass (" not Lu ") Sempervivum tectorum (" detailed outline ")

Base is former: be the heavy peristome Radix Angelicae Sinensis of samphire, Angelica pubescens, Xingan's Radix Angelicae Dahuricae, purple stem Radix Angelicae Pubescentis, Radix Heraclei hemsleyani, the root and rhizome of fur Radix Angelicae Pubescentis and Araliaceae Shi Yong Cortex araliae chinensis etc.

Composition: Angelica pubescens contains angelol, angelicin, bergapton, osthole, umbelliferone, scopoletin, angelic acid .beta.-methylacrylic acid, Palmic acid, stearic acid, oleic acid, linolenic acid, plant sterol, glucose and a small amount of volatile oil.Fur Radix Angelicae Pubescentis root contains Radix Angelicae Dahuricae element, bergenin, bergapton, xanthotoxin, sphondin, multiple furoeoumarin class such as isopimpinellin.

Pharmacology: 1. calm, hypnosis, analgesia, antiinflammatory action: rat given by Radix Angelicae Pubescentis decoct or fluid extract or mice is oral or lumbar injection, all can produce calmness and cause syngignoscism, even can prevent the convulsions effect of strychnine to the frog, but can not make it avoid death.Prove that with the mice hot plate method it has analgesic activity.Radix Angelicae Pubescentis et Herba Taxilli Decoction has calmness equally, and the hypnoanalgesia effect has antiinflammatory action to rat formaldehyde " arthritis ".

2. to the effect of cardiovascular system: the Radix Angelicae Pubescentis crude preparation by using gives anesthetized dog or cat intravenous injection, and hypotensive effect is arranged, but not lasting.The tincture effect is greater than decoct.Isolated frog heart there is inhibitory action.When decoct pours at frog lower limb, pressor effect is arranged.3. other effects: Radix Angelicae Pubescentis can make the frog rectus abdominis m. that exsomatizes shrink.Decoct in vitro (1: 100) has some antibacterial action to the Bacillus tuberculosis.

Nature and flavor: arduous, temperature.

Gui Jing: go into kidney, urinary bladder channel.

Function cures mainly: dispel the wind, win and wet, cold expelling, pain relieving.Control anemofrigid-damp arthralgia, soreness of waist and knee joint, trick spasm and pain, chronic tracheitis, headache, toothache.

Compatibility and incompatibility of drugs: the careful clothes of the dry person of deficiency of YIN blood.

Bungarus Parvus is a principal agent in the medicated wine in the medicated wine prescription of the present invention, its property sweet-salty, and temperature is poisonous, has wind-damp dispelling, and the effect of saturating muscles and bones is the good medicine of traditional treatment rheumatic arthralgia.As (" beautiful autumn medicine the is separated ") joint of being open to the custom, let out wet wind dispelling.Its main component of modern pharmacological research is a snake venom, has the effect of blood vessel dilating and pain relieving.Scorpio has and dispels the wind in the side, relieving convulsion, and collateral dredging, the merit of detoxifcation, as the Zhang Shouyi cloud: " scorpion is the poisonous insect acrid in the mouth.It can make wind person, lid to be good at walking to scurry so, then wind is excessive dispels, and arthralgia chiefly caused by damp pathogen can be sharp." modern pharmacological research shows that it mainly contains scorpion venom, is the Neurotoxic protein of a kind of similar snake venom, arthromyodynia is not only had analgesic effect, and feeling of numbness is also had therapeutical effect, the snakes and scorpions compatibility has increased treatment pain disease effect.Radix Aconiti Preparata is hot poisonous, and dispelling cold and dampness is arranged, the ailment said due to cold or exposure of loosing, and the effect of antalgic is controlled anemofrigid-damp arthralgia, the severe and migratory arthralgia pain; Radix Aconiti Kusnezoffii is hot poisonous, cures mainly to search wind prevailing over dampness the cold expelling reducing swelling and alleviating pain, control anemofrigid-damp arthralgia, the pain relieving of the collaborative reinforcement of Sichuan Cordyceps two crows expelling wind and cold, modern pharmacological research proves: Radix Aconiti and Radix Aconiti Kusnezoffii effect are basic identical, and it is anti-inflammatory analgesic that Radix Aconiti contains 6 kinds of alkaloid main pharmacological.Aconitine makes the adrenocortical hormone excitation.The Radix Clematidis wind-damp dispelling, the dysmenorrhea network, stopping numbness pain is walked 12 warps; Herba Asari has the capable water of expelling wind and cold and opens the effect of stealing, and " Herba Asari, the wind medicine also for cloud as " book on Chinese herbal medicine is dredged warp "." the wind liter, rise then uply, suffering is then horizontal to be walked, and Wen Ze disperses.So treating as above, wind and cold wets disease also.Join Rhizoma Cibotii with the strong waist of the kidney invigorating; 5 Flos Carthamis are followed the ancient medical knowledge of the traditional Chinese medical science " control wind and control blood earlier, the blood sector-style is from going out " with phlegm reduction of blood circulation promoting.Ramulus Cinnamomi is with the diaphoresis expelling pathogenic factors from muscles, and warming the meridian is network bitterly, and modern pharmacological research shows to have antiinflammatory action.Fructus Chaenomelis is with the Shujin that dries; The Radix Cyathulae conducting blood to flow downwards, the promoting blood circulation by removing wind dampness removing; Join the Rhizoma Homalomenae strengthening bone and muscle as " book on Chinese herbal medicine justice " cloud: " Rhizoma Homalomenae, modern perseverance is used for ventilation meridian, dispels the wind by numbness, has wide experience.The lid abnormal smells from the patient is all thick, and the effect that also hot temperature is walked to scurry also." " detailed outline is picked up any lost article from the road " " strengthening bone and muscle infusing drugs in wine; End stomachache, wine mill clothes." the wet sharp joint of notopterygium wind dispelling is as " product converge smart wanting ": " main all joints being painful all over, flesh table eight winds coming from eight orientations harmful climatic factors is except that new and old rheumatism." principal agent of Radix Angelicae Pubescentis expelling wind and dampness collateral dredging.Fructus Lycii nourishing kidney tonifying liver makes eye bright.Kidney governing bones, liver governing tendons." eating the Liao Dynasty's book on Chinese herbal medicine ": " hard muscle is anti-old, removes wind, tonification muscles and bones, and the beneficial people of energy goes empty old." " book on Chinese herbal medicine converges and says " cloud: " and-----wet dissipation must be with grey, and Piao dispels the wind and must use Qiang, and solely, Radix Saposhnikoviae hardly realizes that Fructus Lycii can make gas fill, and blood can be mended, Yang Kesheng, and the moon can be grown, and fire can fall, and rheumatism can be gone, and perfect magical effect is arranged here." Flos Lonicerae can alleviate toxic and side effects, compatibility white sugar had both been regulated the taste of medicated wine, and benefiting vital QI and blood is arranged, the effect of reinforcing body resistance, and Chinese liquor has all medicines of reinforcement, the effect that thin muscle is invigorated blood circulation.

Toxicity research, this bone strengthening blood-activating wine that dispels the wind belongs to oral medicinal liquor, is made up of above medicine, though the minority medicine is poisonous, as Liquor infusion, dose is again little, adds Flos Lonicerae with detoxifcation, Fructus Lycii, white sugar benefiting vital QI and blood, so reinforcing body resistance is no obvious toxic-side effects.And the wine effect of invigorating blood circulation cooperates said medicine promptly to control anemofrigid-damp arthralgia, can eliminate one day fatigue again.Be not suitable for the alcohol user and avoid clothes.

Get pure dried medical material, pour in the 50 degree Chinese liquor, be encapsulated in the altar after 10 days, it is oral to open altar, oral 2 times of every day, each 5-20ml.Oral every night 1 time of the lighter, each 5ml.The present invention has wind-damp dispelling, strengthening bone and muscle, and the meridian dredging, the tired effect that disappears cures mainly by the wet rheumatalgia that causes of wind and cold, arthralgia, sciatica is overworked, diseases such as neck-shoulder pain, lumbago and leg pain.Medicated wine with 1 kilogram of preparation of Chinese liquor consumption is a material medicated wine, and whenever taking 3 material is a course of treatment.Take medicated wine of the present invention, promptly produce effect after the course of treatment.

The characteristics of medicine of the present invention are that curative effect is quick, cheap, making is simple, taking convenience.Maximum defective is a gastropathy, and the patient that gives up alcohol such as hepatopathy prohibits clothes.

Drug effect: chase after the wind dispelling cold and dehumidification, bone and muscle strengthening collateral dredging, promoting blood circulation, removing blood stasis and relieving pain.Eliminate physical fatigue.Cure mainly: by the wet rheumatalgia that causes of wind and cold, arthralgia, neuralgia, pain of neck, shoulder, waist and leg, the functional rehabilitation of overworking etc.Medication 1 material promptly has remarkable result, and clinical cure rate reaches 80%, effective percentage 95%.

The specific embodiment

The present invention is described in further detail below in conjunction with embodiment.

Embodiment 1 the present invention treats the clinical observation of lumbar muscle strain

1.1 lumbar muscle strain diagnosis and symptom: lumbar muscle strain is meant waist muscle, fascia and ligament tissue chronic injury, pathogenic factor can reduce three: first, the long-term work posture is bad as bend over, lift weight pickaback or habitual posture is bad with a side, make psoas muscle be in the drawing-off state for a long time, cause cumulative bad strain degeneration soft tissue fatigue then to produce aching pain in waist and back.The second, the congenital or posteriority deformity of lumbar vertebra, or lower limb cripetura deformity, or after the waist wound, long-term bed, back flesh length fatigue etc.The 3rd, lumbar soft tissue acute injury malpractice, or damage can not be fully repaired tissue repeatedly, produces fibrosis or cicatrization, also is the reason of chronic abdominal pain.The traditional Chinese medical science then think " impairment of blood by looking for a long time, the excessive rest on bed impairing QI prolonged sitting injuring the muscles, the prolonged standing injuring bones prolonged walking injuring tendons, be the meaning five wounds ".It is improper to have illustrated work and rest, and the movable imbalance of QI and blood muscles and bones has caused the tissue strain.

Primary disease is sent out in the adult well, waist or waist and sacrum pain, outbreak repeatedly, pain can change with climate change or tired degree, the time heavy when light, touchingly do not heal.Waist can have far-ranging pressure sick, and how no abnormal the vertebra activity is, and various symptoms all obviously increase the weight of during acute attack, and well can have muscle spasm, scoliosis, and the physiology prolapse changes.Indivedual diversionary pain of lower limb, but do not have string pain and numbness of the skin sense.The character of pain mostly is dull pain, can limit to a position, also spreadable entire back, but do not have certain pressure pain point.Psoas muscle does not have obvious spasm.

1.2 use medicinal liquor prescription:

Bungarus Parvus 2g, Scorpio 10g, Radix Aconiti Preparata 20g, Radix Aconiti Kusnezoffii Preparata 10g, Radix Clematidis 10g, Herba Asari 20g, Rhizoma Cibotii 25g, Flos Lonicerae 10g, Flos Carthami 10g, Ramulus Cinnamomi 10g, 50 degree Chinese liquor 1000g.

1.3 clinical statistics is observed:

Accept patient's 660 examples for medical treatment, cure 580 examples in the course of treatment, improve 72 examples, effective percentage 98.8%.

Embodiment 2 sciatica

2.1 diagnosis and symptom: sciatica is made up of waist 4～sacrum 3 nerve rooies, enters behind the pelvis process before sacro-iliac joints, passes piriformis from greater sciatic formaen and reaches buttocks, 1/3 to punish be tibial nerve and common peroneal nerve down to burst back along burst portion back.Tibial nerve comes downwards to the vola along facies cruralis posterior, common peroneal nerve along anterolateral crural to the instep.Sciatica means the pain syndrome of sciatic nerve path and areal area thereof, and its cause of disease can be divided into constitutional and Secondary cases two big classes.The primary sciatica cause of disease is not clear and definite as yet, and more rare; The Secondary cases sciatica then is more common in pathological changes and intervertebral disc in the canalis spinalis, vertebral disease (causing sciatica of nerve roots), or pelvic cavity and pelvis illness (causing the dryness osteoneuralgia).

Diagnostic point: one, a side waist, pain of buttock and be sidelong to thigh rear side, the shank outside and instep and penetrate.Two, feel to go down in the shank outside and instep.Three, suffer from the limb hypomyotonia, obvious with shank especially, course of disease elder often has the slight atrophy of Calf muscle.Four, the Achilles jerk lowers or disappears.Five, along sciatic nerve-trunk tenderness is arranged, Lasegue levies the positive, and (patient lies on the back, and lower limb stretch, and the examiner will suffer from limb and raise, and brings out in 70 degree or aggravates lumbago and skelalgia.

2.2 use medicinal liquor prescription:

Bungarus Parvus 1g, Scorpio 25g, Radix Aconiti Preparata 10g, Radix Aconiti Kusnezoffii Preparata 20g, Radix Clematidis 20g, Herba Asari 10g, Rhizoma Cibotii 10g, Flos Lonicerae 25g, Flos Carthami 25g, Ramulus Cinnamomi 20g, Fructus Chaenomelis 10g, Fructus Lycii 10g, Radix Cyathulae 20g, dried Rhizoma Homalomenae 20g, Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Pubescentis 20g, 50 degree Chinese liquor 1000g.

2.3 clinical statistics is observed:

Accept patient's 430 examples for medical treatment, cure 402 examples in the course of treatment, improve 20 examples, effective percentage 98.1%.

Embodiment 3 cervical spondylosiss

3.1 diagnosis and symptom: cervical spondylosis is meant that degeneration of cervical intervertebral disc, hyperosteogeny of cervical vertebra and neck injury etc. cause cervical part of esophagus spinal column internal and external equilibrium imbalance, stimulates or compressing cervical region nerve, blood vessel and produce a series of symptoms.Mainly show as neck and shoulder pain, dizziness headache, upper limb numbness, amyotrophy, the two lower limb spasm of severe patient, difficulty in walking, even quadriplegia, hemiplegia appears in the defecation obstacle.Primary disease claims cervical vertebra syndrome or cervical-shoulder syndrome again.Multiple at middle-aged and elderly people, male's sickness rate is higher than the women.

3.2 use medicinal liquor prescription

Bungarus Parvus 1g, Scorpio 15g, Radix Aconiti Preparata 12g, Radix Aconiti Kusnezoffii Preparata 18g, Radix Clematidis 16g, Herba Asari 12g, Rhizoma Cibotii 20g, Flos Lonicerae 15g, Flos Carthami 15g, Ramulus Cinnamomi 20g, white sugar 500g, 50 degree Chinese liquor 1000g.

3.3 clinical statistics is observed

Accept patient's 520 examples for medical treatment, cure 480 examples in the course of treatment, improve 25 examples, effective percentage 97.1%.

Embodiment 4 rheumatic arthritis

4.1 diagnosis and symptom: the pathogenic factor of primary disease be it is generally acknowledged with the caused allergy of pharyngeal streptococcal infection substantial connection.Because the antibody that produces in streptococcal antigen material and the body forms immune complex, be deposited on easily on the collagen protein that synovium of joint etc. locates, or certain component of organization at these positions is similar to antigenic structure, the result has excited intravital systemic immune response and has caused that the local inflammation that is involved the position damages, and makes joint and surrounding structure thereof produce a series of pathological changes.

There is the streptococcal infection history in patient's premorbid 1-4 weeks more than half, as acute tonsillitis, angina etc.Then occur that joint symptom or other are double sees disease.

1. joint symptom.Onset is anxious, and the big joint of extremity (wrist, shoulder, ankle, knee joint, hip) occurs red, swollen, hot, bitterly, or swelling distortion and movable function are limited.Wherein see so that knee joint, ankle joint more.Clinical have multiple, migration, symmetry, easy characteristics such as outbreak repeatedly.The minority case can be involved the little joint of neck, temporo, lower jaw or hands.

2. doublely see disease.Part patient can generate heat with light or moderate, but how irregular.Erythema appears in a few patients skin, is distributed in trunk and extremity inboard more, and it is very fast to disappear; Or visible subcutaneous nodule, shape such as Semen Pisi sativi, matter is slightly hard, does not have and touches a tender spot, and is distributed in behind elbow, knee joint, the pillow etc. to locate more.If pathological changes is involved heart, then performance such as had palpitation, pareordia discomfort, cardiac insufficiency (seeing rheumatic heart disease) appears in severe patient.

4.2 use medicinal liquor prescription

Bungarus Parvus 2g, Scorpio 20g, Radix Aconiti Preparata 15g, Radix Aconiti Kusnezoffii Preparata 15g, Radix Clematidis 15g, Herba Asari 15g, Rhizoma Cibotii 20g, Flos Lonicerae 20g, Flos Carthami 20g, Ramulus Cinnamomi 15g, Fructus Chaenomelis 15g, Fructus Lycii 15g, Radix Cyathulae 15g, dried Rhizoma Homalomenae 15g, Rhizoma Et Radix Notopterygii 15g, Radix Angelicae Pubescentis 15g, white sugar 500g, 50 degree Chinese liquor 1000g.

4.3 clinical statistics is observed

Accept patient's 500 examples for medical treatment, cure 450 examples in the course of treatment, improve 46 examples, effective percentage 99.2%.

Embodiment 5 rheumatoid arthritiss

5.1 diagnosis and symptom: Americanism damp disease association in 1987 propose the criteria for classification of rheumatoid arthritis.4 persons in following 7 are arranged, and diagnosable is rheumatoid arthritis:

1. morning, deadlock continued 1 hour at least.

2. joint swelling simultaneously more than 3 or 3 arranged or hydrops is arranged.These joints comprise that (bilateral proximal interphalangeal joint and metacarpophalangeal joints is impaired and DIPJ is not often got involved is one of feature of rheumatoid arthritis for bilateral proximal interphalangeal joint, metacarpophalangeal joints, carpal joint, elbow joint, knee joint, ankle joint and metatarsophalangeal joints.About 80% rheumatoid arthritis patients has the many gaps of wrist to get involved, and the swelling of processus styloideus ulnae place also has tenderness and dorsal part extensor stndon sheath that tenosynovitis is arranged, and these all are the early stage signs of rheumatoid arthritis.The foot joint of rheumatoid arthritis patients is also often got involved.Metatarsophalangeal joints often is inflamed, and the far-end interphalangeal joint is seldom got involved.Head of metatarsal bone can form the deformity that toes stick up when the subluxation of vola).

3. have 1 arthroncus in metacarpophalangeal joints, proximal interphalangeal joint or the carpal joint at least or hydrops is arranged.

4. in 2 cited joints, the joint of symmetrical swelling or hydrops appears simultaneously.

5. subcutaneous rheumatoid nodules.

6. the rheumatoid factor positive (the RF titre that titre＞1: 32, the method therefor positive rate in normal population is no more than 5%, 90% RA patient is 1: 256, and high titre RF is more special relatively concerning RA).

7. to show bone erosion narrow or clear and definite osteoporosis arranged for the postero-anterior position X skiagram of hands and wrist.

5.2 use medicinal liquor prescription

Bungarus Parvus 1g, Scorpio 15g, Radix Aconiti Preparata 12g, Radix Aconiti Kusnezoffii Preparata 18g, Radix Clematidis 12g, Herba Asari 18g, Rhizoma Cibotii 15g, Flos Lonicerae 15g, Flos Carthami 15g, Ramulus Cinnamomi 12g, Fructus Chaenomelis 20g, Fructus Lycii 20g, Radix Cyathulae 10g, dried Rhizoma Homalomenae 10g, Rhizoma Et Radix Notopterygii 20g, Radix Angelicae Pubescentis 10g, white sugar 500g, 50 degree Chinese liquor 1000g.

5.3 clinical statistics is observed

Accept patient's 260 examples for medical treatment, cure 180 examples in the course of treatment, improve 70 examples, effective percentage 96.2%.

Embodiment 6 tired transition

6.1 diagnosis and symptom: the fatigue of outbreak lastingly or repeatedly continues more than 6 months; According to medical history, sign or lab testing result, can get rid of the various organic diseases that cause confirmed fatigue.Low grade fever, 37.5 ℃～38 ℃ of oral temperatures; Can touch cervical lymph node enlargement or tenderness less than 2 centimetres; Pharyngeal congestion, but do not have clear and definite tonsil inflammation; Do not find that other cause tired disease sign.

Symptom: the 1. overweight fatigue of be difficult for removing that causes of muscle power or mental workload; 2. the muscle weakness that does not have clear and definite reason; 3. insomnia ubiquity, dreaminess or early awakening; Head rise, dizzy or headache; 5. difficult concentrating, hypomnesis; 6. inappetence; 7. shoulder back discomfort, chest have constriction, or the myalgia and the arthralgia of lumbago and backache, delocalization are arranged, no clear and definite rheumatism or trauma history; 8. feel depressed, anxiety or anxiety, fear; 9. interest goes down or loses; 10. sexual hypofunction; 11. low grade fever; 12. there are constriction in dry pharynx, pharyngalgia or throat.

6.2 use medicinal liquor prescription

Bungarus Parvus 1g, Scorpio 15g, Radix Aconiti Preparata 16g, Radix Aconiti Kusnezoffii Preparata 12g, Radix Clematidis 18g, Herba Asari 18g, Rhizoma Cibotii 20g, Flos Lonicerae 20g, Flos Carthami 15g, Ramulus Cinnamomi 15g, 50 degree Chinese liquor 1000g.

6.3 clinical statistics is observed

Accept patient's 800 examples for medical treatment, cure 780 examples in the course of treatment, improve 15 examples, effective percentage 99.4%.

Embodiment 7 hyperosteogenys

7.1 diagnosis and symptom: bone matrix hyperplasia is called hyperplastic osteoarthritis, osteoarthritis (OA), degenerated arthrosis, senile arthritis, hypertrophiarthritis again, be because soft tissue degeneration, degenerations such as the cartilage in formation joint, intervertebral disc, ligaments, the edge, joint forms bony spur, variations such as synovial membrane plumpness, and osteoclasia appears, cause insecondary hyperosteogeny, cause joint deformity, when being subjected to abnormal load, cause arthralgia, a kind of disease of symptoms such as limitation of activity.Divide two kinds of constitutional and Secondary cases.

7.2 use medicinal liquor prescription

Bungarus Parvus 1g, Scorpio 10g, Radix Aconiti Preparata 15g, Radix Aconiti Kusnezoffii Preparata 20g, Radix Clematidis 10g, Herba Asari 16g, Rhizoma Cibotii 18g, Flos Lonicerae 16g, Flos Carthami 20g, Ramulus Cinnamomi 10g, Fructus Chaenomelis 20g, Fructus Lycii 10g, Radix Cyathulae 12g, dried Rhizoma Homalomenae 16g, Rhizoma Et Radix Notopterygii 12g, Radix Angelicae Pubescentis 12g, white sugar 500g, 50 degree Chinese liquor 1000g.

7.3 clinical statistics is observed

Accept patient's 250 examples for medical treatment, cure 180 examples in the course of treatment, improve 58 examples, effective percentage 95.2%.

Claims (6)

1. treat rheumatism, rheumatoid medicated wine for one kind, its crude drug is formed and weight portion is: Bungarus Parvus 1-2 part, Scorpio 10-25 part, Radix Aconiti Preparata 10-20 part, Radix Aconiti Kusnezoffii Preparata 10-20 part, Radix Clematidis 10-20 part, Herba Asari 10-20 part, Rhizoma Cibotii 10-25 part, Flos Lonicerae 10-25 part, Flos Carthami 10-25 part, Ramulus Cinnamomi 10-20 part.

2. according to claim 1 treatment rheumatism, rheumatoid medicated wine, described crude drug is formed and weight portion is: 2 parts of Bungarus Parvus, 20 parts of Scorpios, 15 parts of Radix Aconiti Preparatas, 15 parts of Radix Aconiti Kusnezoffii Preparatas, 15 parts of Radix Clematidis, 15 parts of Herba Asari, 20 parts of Rhizoma Cibotii, 20 parts of Flos Loniceraes, 20 parts on Flos Carthami, 15 parts of Ramulus Cinnamomi.

3. according to claim 2 treatment rheumatism, rheumatoid medicated wine, also contain Fructus Chaenomelis 10-20 part in its crude drug, Fructus Lycii 10-20 part, Radix Cyathulae 10-20 part, dried Rhizoma Homalomenae 10-20 part, Rhizoma Et Radix Notopterygii 10-20 part, Radix Angelicae Pubescentis 10-20 part.

4. treatment rheumatism according to claim 3, rheumatoid medicated wine, 15 parts of described Fructus Chaenomeliss, 15 parts of Fructus Lycii, 15 parts of Radix Cyathulaes, 15 parts of dried Rhizoma Homalomenae, 15 parts of Rhizoma Et Radix Notopterygiis, 15 parts of Radix Angelicae Pubescentiss.

5. treatment rheumatism according to claim 4, rheumatoid medicated wine also contain white sugar.

6. treatment rheumatism according to claim 5, rheumatoid medicated wine, described wine are 50 degree Chinese liquor, and the weight ratio of crude drug and 50 degree Chinese liquor is 1: 3-10, the weight ratio of white sugar and 50 degree Chinese liquor is 1: 2.