CN101019960A - Medicine for treating femoral head necrosis - Google Patents
Medicine for treating femoral head necrosis Download PDFInfo
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- CN101019960A CN101019960A CN 200710055426 CN200710055426A CN101019960A CN 101019960 A CN101019960 A CN 101019960A CN 200710055426 CN200710055426 CN 200710055426 CN 200710055426 A CN200710055426 A CN 200710055426A CN 101019960 A CN101019960 A CN 101019960A
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Abstract
The present invention is one kind of Chinese medicine for treating femoral head necrosis, and belongs to the field of Chinese medicine technology. The Chinese medicine is prepared with over ten kinds of Chinese medicinal materials, including prepared rhizome of rehmannia, angelica, corydalis tuber, achyranthes root, red sage, etc. It has the functions of promoting blood circulation, regulating qi, dispelling cold, removing dampness, warming meridian, etc. and possesses high curative effect, less toxic side effect and other advantages.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of femur head necrosis, belong to the field of Chinese medicines.
Background technology
Femur head necrosis is the difficult disease that world's orthopaedics is generally acknowledged, its serious harm human beings'health gently then makes the people disable, and is heavy then the people is paralysed, and forfeiture is worked and self care ability.The cause of disease that generally believes femur head necrosis mainly contains: wound, hormone, excessive drinking or osteoporosis etc.Main clinic symptoms is pain and hip joint movable function obstacle.For this disease, mainly take conservative treatment, late period then to adopt artificial replacement's art early stage.Though have the medicine of multiple treatment femur head necrosis to occur at present, exist shortcomings such as prescription is numerous and diverse, cost is high, the course of treatment is long, side effect is big, curative effect is undesirable in various degree.
Summary of the invention
The objective of the invention is at above-mentioned deficiency, the medicine of a kind of prescription uniqueness, cost treatment femur head necrosis low, safe and reliable, evident in efficacy is provided.
Drug main of the present invention will be selected ten multi-flavor natural Chinese medicinal herb such as Radix Rehmanniae Preparata, Radix Angelicae Sinensis, Rhizoma Corydalis, Radix Achyranthis Bidentatae, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Radix Salviae Miltiorrhizae, Radix Dipsaci, Rhizoma Drynariae, the Radix Aucklandiae, Rhizoma Chuanxiong, Herba Taxilli for use, through scientific and reasonable compatibility, make the effect of each medicine produce synergism, thereby reach the purpose of effective treatment femur head necrosis.
Monarch drug: Radix Rehmanniae Preparata, Radix Angelicae Sinensis mediator body immunity function, antianaphylaxis, increase bone marrow, longue meat, promoting generation of vital essence and blood, tonifying five ZANG-organs internal injury deficiency at liver and kidney tonifying.The Radix Salviae Miltiorrhizae promoting blood circulation to restore menstrual flow improves the anoxia enduring power of human body, and coronary artery dilator improves myocardial contraction, promotes the reparation and the regeneration of tissue, activates fibrinolytic anticoagulant, and is calm and adjust in the body immunologic function etc.But the Rhizoma Chuanxiong blood-activating and qi-promoting, treating swelling and pain by traumatic injury, rheumatic arthralgia, and blood vessel dilating is arranged, and coronary blood flow increasing and myocardium shrinkage function improve blood circulation, and anticoagulant reduces thrombosis etc.Radix Achyranthis Bidentatae energy liver and kidney tonifying, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, caused by liver and kidney deficiency, soreness of waist and knee joint etc.
Ministerial drug: Herba Taxilli, Rhizoma Corydalis, the energy liver and kidney tonifying removes rheumatism, and bone and muscle strengthening also has blood pressure lowering, coronary artery dilator effect.The Rhizoma Corydalis blood circulation promoting regulates qi, pain relieving, functions such as diuresis and traumatic injury.
Left side medicine: Rhizoma Drynariae, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), invigorating kidney, promoting blood circulation is used for occlusive syndrome, thrombophlebitis and blood capillary microcirculation disturbance.
Messenger drug: the Radix Dipsaci invigorating the liver and kidney, the promoting the circulation of blood arteries and veins, reuniting the fractured tendons and bones, pain relieving, granulation promoting meat is mended five kinds of strain and seven kinds of impairment, helps gas.The hot temperature of the Radix Aucklandiae, regulating QI to relieve pain.
The objective of the invention is to be achieved through the following technical solutions.
The medicine of this treatment femur head necrosis, make by following raw medicaments in portion by weight:
Radix Rehmanniae Preparata 20-2 part, Radix Angelicae Sinensis 20-10 part, Rhizoma Corydalis 15-5 part, Radix Achyranthis Bidentatae 16-10 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 20-10 part, Radix Salviae Miltiorrhizae 20-7 part, Radix Dipsaci 20-10 part, Rhizoma Drynariae 20-10 part, Radix Aucklandiae 4-2.5 part, Rhizoma Chuanxiong 15-5 part, Herba Taxilli 16-10 part.
Each amounts of components all has better curative effect in the following weight parts scope:
Radix Rehmanniae Preparata 18-13 part, Radix Angelicae Sinensis 16-12.5 part, Rhizoma Corydalis 14.5-11 part, Radix Achyranthis Bidentatae 15-11.5 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 17-13.8 part, Radix Salviae Miltiorrhizae 18-10.5 part, Radix Dipsaci 19-12 part, Rhizoma Drynariae 18.5-13 part, Radix Aucklandiae 3.7-2.8 part, Rhizoma Chuanxiong 14-8.8 part, Herba Taxilli 14-11.2 part.
Be preferably:
17 parts of Radix Rehmanniae Preparata, 14 parts of Radix Angelicae Sinensis, 13 parts of Rhizoma Corydalis, 12 parts of Radix Achyranthis Bidentataes, 14.5 parts of Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.)s, 16 parts of Radix Salviae Miltiorrhizaes, 16 parts of Radix Dipsacis, 15 parts of Rhizoma Drynariae, 3.2 parts of the Radix Aucklandiae, 12 parts of Rhizoma Chuanxiongs, 12 parts of Herba Taxillis.
In order further to improve curative effect, the medicine of treatment femur head necrosis of the present invention can also add following raw medicaments in portion by weight and make:
Radix Notoginseng 16-10 part, Borneolum Syntheticum 10-5 part, Caulis Spatholobi 20-2 part.
Be preferably:
13 parts of Radix Notoginseng, 6 parts of Borneolum Syntheticums, 15 parts of Caulis Spatholobis.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation, and required various conventional adjuvant was prepared into any conventional oral preparations when the active component of medicine of the present invention was added the preparation different dosage form.For example these crude drug pulverize mix homogeneously can be made powder, pill or made capsule, tablet; Can or extract active component and make oral liquid these crude drug decoctings, condensed water decocting liquid, also can make powder, capsule etc. pulverizing behind the extracting solution concentrate drying.But these can not be used to limit protection scope of the present invention.
Medicament composing prescription uniqueness of the present invention, each component drug synergism complements each other, blood circulation promoting regulates qi, dispelling cold and removing dampness, promoting the flow of QI-blood by warming the meridian, bone and muscle strengthening, the liver and the kidney tonifying, tissue regeneration promoting pain relieving, replenishing QI and blood, sharp heart and brain, the warming the meridian arteries and veins, necrosis has better curative effect to caput femoris aseptic ischemic.Have that preparation technology is simple, cost is low, dosage is little, the efficacy of a drug is big, taking convenience, safe and reliable, characteristics such as therapeutic effect is remarkable, side effect is little, total effective rate reaches 98.1%.
The specific embodiment
Below by embodiment the present invention is further described.But the present invention is not limited to embodiment, and those of ordinary skills do some modification, all in protection domain of the present invention.
Embodiment 1-5: the preparation of the pill of medicine of the present invention
(the unit: kilogram) see Table 1 of the consumption of each crude drug among each embodiment.
Table 1
| Embodiment number | 1 | 2 | 3 | 4 | 5 |
| Radix Rehmanniae Preparata | 20 | 18 | 17 | 13 | 2 |
| Radix Angelicae Sinensis | 20 | 16 | 14 | 12.5 | 10 |
| Rhizoma Corydalis | 15 | 14.5 | 13 | 11 | 5 |
| Radix Achyranthis Bidentatae | 16 | 15 | 12 | 11.5 | 10 |
| Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) | 20 | 17 | 14.5 | 13.8 | 10 |
| Radix Salviae Miltiorrhizae | 20 | 18 | 16 | 10.5 | 7 |
| Radix Dipsaci | 20 | 19 | 16 | 12 | 10 |
| Radix Notoginseng | 16 | 14 | 13 | 11 | 10 |
| Rhizoma Drynariae | 20 | 18.5 | 15 | 13 | 10 |
| The Radix Aucklandiae | 4 | 3.7 | 3.2 | 2.8 | 2.5 |
| Rhizoma Chuanxiong | 15 | 14 | 12 | 8.8 | 5 |
| Borneolum Syntheticum | 10 | 8 | 6 | 5.8 | 5 |
| Herba Taxilli | 16 | 14 | 12 | 11.2 | 10 |
| Caulis Spatholobi | 20 | 17 | 15 | 8.6 | 2 |
Preparation method: after described materials of weight proportions medicine screened purified treatment respectively by different pharmacological properties, after soaking, decoct its effective ingredient of extraction according to a conventional method, concentrate the honeyed pill of two kinds of medicines of the present invention making every ball 7.5 grams (No. 1, bone) and 0.9 gram (No. 2, bone).
The honeyed pill of medicine of the present invention, treat each option share bone aseptic ischemic necrosis, its usage and dosage:
After morning every day, the supper: 1 ball, 7.5 gram big honeyed pills (No. 1, bone) are obeyed at each eliminating cold for resuscitation mouth of a river; 1 ball, 0.9 gram small honey pill (No. 2, bone) is obeyed in the eliminating cold for resuscitation mouth of a river half an hour again in the clothes back.Every day is p.prand: 1 ball, 0.9 gram small honey pill (No. 2, bone) is obeyed at each eliminating cold for resuscitation mouth of a river.
General just, mid-term the patient take and get final product disease controlling 1-2 the course of treatment (3 months each courses of treatment), throw away crutch, dried light muscular labor; Can fully recover 2-4 the course of treatment, various transference cures.
Period in a medicine is noted: quit smoking, wine, peppery food; Few sexual life; Liver, renal insufficiency, the careful usefulness of hyperpietic; After having taken 1 month medicine, but rest 10-15 days, obey medication next month again, the rest may be inferred, if any discomfort drug withdrawal at once.
Show through clinical trial for many years, medicine of the present invention promptly has the liver and kidney tonifying medicine, there is strong bone to mend the marrow medicine again, the QI regulating medicine of promptly enriching blood, also has blood circulation and stasis-eliminating medicine, not sad, brain, liver,kidney,spleen, stomach, lung are a kind of good medicine for the treatment of the caput femoris aseptic ischemic necrosis, do not need to have an injection in addition, lean on turn, auxiliary therapy such as traction.Have that dosage is little, the efficacy of a drug is big, good absorbing, taking convenience, conditioning comprehensively, advantage such as safe and reliable.Medicine of the present invention also has certain therapeutical effect to diseases such as cervical vertebra, lumbar vertebra, hyperosteogenys.
Criterion of therapeutical effect: judge and rattan justice and criterion of therapeutical effect with reference to X-P in the 108th page " femur head necrosis therapeutic evaluation " in " integrative therapy femur head necrosis " (Guo Yongchang, Deng like the democracy volume, and publishing house of Henan Medical Univ. publishes) book.
(1) outstanding: pain disappears, and joint motion is normal, and X-P judges the image that reparation is arranged.
(2) good: pain obviously alleviates or disappearance substantially, and hip joint is movable obviously to be improved, and takes care of oneself, and abandons and turns walking, and X-P judges that the part sclerotin has the existing picture of reparation.
(3) can: pain relief, funtion part recover, and life still can be taken care of oneself, and X-P judges that sclerotin repairs existing picture to some extent.
(4) poor: pain does not subtract, walk lamely obviously, and the difficulty of squatting down, life inconvenience, X-P judges that bone destruction is serious.
Treated case with medicine of the present invention and reached 110 many cases, determined curative effect, that wherein cures (outstanding, good) fully accounts for 60.0%, the basic healing (can) account for 29.1%, total effective rate reaches 89.1%.
Following selection portion is divided the curative effect of healing case history with explanation medicine of the present invention.
Case history 1: Zhao Zhongli, the man, 47 years old, nineteen eighty-three was because of the non-specific encephalitis hormone of 2 wheat harvesting periods, after the nineteen ninety right hip joint wound, right lower extremity, the right hip arthralgia appear, in JIUYUE, 1992 X-radiodiagnosis x has the femoral head crackle, and that the outer place of femoral head has is cracked, subside, and walking limping pain increases the weight of by the sky, can't take care of oneself, it is early stage to be diagnosed as the right lateral thigh head necrosis.Successively arrive ground such as Changchun, Shenyang, Beijing, Shanghai, Guangzhou, all ineffective through a lot of hospitalizes, the state of an illness is serious day by day.Rise May nineteen ninety-five, takes medicine of the present invention after 4 months, and the sick lower limb that atrophy such as bavin walking are walked lamely recovers normal, walk freely, and cracked, the disappearance of subsiding of X-radiodiagnosis x femoral head, the little Beam of bone arranges fine and close, cures fully.Visit not recurrence in 10 years.The second hospital radiological department X-ray examination report of December in 2006 Jilin on the 26th shows: " right lateral thigh bone contour line is continuous and clear and smooth, and the joint space is high-visible.The outer bone density of femoral head increases, the little Beam of bone as seen, the frog position formula is observed joint motion and is reached functional position." therapeutic evaluation is: the right lateral thigh head necrosis, the reparation phase, X-P is judged to be outstanding.
Case history 2: Zhang Changyu, the man, 55 years old, caused left side femoral head cracked, subside interior place distortion because of wound and hormone in June, 2000.Suffer from limb and serious hindrance occurs, lean on crutches.Take medicine of the present invention after 1 course of treatment, cure substantially, throw away crutches in JIUYUE, 2000; Cure fully after taking 2 courses of treatment again, activity freely.X-P is judged to be outstanding.
Case history 3: Tang Xiujuan, the woman, 51 years old, because of other diseases cause the necrosis of fl head with hormone, other hospitalizes 3 years, femoral head became flat at that time, distortion, the gap increases, and the thigh atrophy is walked limping, pain unbearably, and defecation inconvenience be can't take care of oneself.Take medicine of the present invention restore funcitons gradually after 1 course of treatment, pain alleviates greatly, and defecation is normal substantially, after take 1 course of treatment again, it is normal that all functions are recovered.X-P is judged to be outstanding.
Case history 4: Shi Yucai, the man 65 years old,, was on the rise earlier after how tame hospitalize be not only invalid because of hormone causes the necrosis of fl head aseptic ischemic in 1999 on the contrary.The femoral head crown subsides, and sequestrum is arranged, and bone density increases, but the transmittance inequality, walking disorder is walked lamely, and stool is inconvenient.Take 2 courses of treatment of medicine of the present invention, the basic healing.The new osteogenesis of X-radiodiagnosis x, sequestrum is absorbed gradually, and bone density is even, and articular surface is smooth and continuous comparatively.X-P is judged to be well.
Case history 5: Li Yulong, the man, 45 years old, hormone and wound caused right femur head necrosis, earlier after how tame hospitalize do not feel any better.Take 2 courses of treatment of medicine of the present invention (6 months), little Beam is high-visible for X-radiodiagnosis x bone, the articular surface smooth and continuous, and the gap is normal substantially, and activity is freely.X-P is judged to be well.
Claims (5)
1, a kind of medicine for the treatment of femur head necrosis is characterized in that being made by following bulk drugs:
Radix Rehmanniae Preparata 20-2 part, Radix Angelicae Sinensis 20-10 part, Rhizoma Corydalis 15-5 part, Radix Achyranthis Bidentatae 16-10 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 20-10 part, Radix Salviae Miltiorrhizae 20-7 part, Radix Dipsaci 20-10 part, Rhizoma Drynariae 20-10 part, Radix Aucklandiae 4-2.5 part, Rhizoma Chuanxiong 15-5 part, Herba Taxilli 16-10 part.
2, the medicine of treatment femur head necrosis according to claim 1 is characterized in that being made by following bulk drugs:
Radix Rehmanniae Preparata 18-13 part, Radix Angelicae Sinensis 16-12.5 part, Rhizoma Corydalis 14.5-11 part, Radix Achyranthis Bidentatae 15-11.5 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 17-13.8 part, Radix Salviae Miltiorrhizae 18-10.5 part, Radix Dipsaci 19-12 part, Rhizoma Drynariae 18.5-13 part, Radix Aucklandiae 3.7-2.8 part, Rhizoma Chuanxiong 14-8.8 part, Herba Taxilli 14-11.2 part.
3, the medicine of treatment femur head necrosis according to claim 1 is characterized in that being made by following bulk drugs:
17 parts of Radix Rehmanniae Preparata, 14 parts of Radix Angelicae Sinensis, 13 parts of Rhizoma Corydalis, 12 parts of Radix Achyranthis Bidentataes, 14.5 parts of Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.)s, 16 parts of Radix Salviae Miltiorrhizaes, 16 parts of Radix Dipsacis, 15 parts of Rhizoma Drynariae, 3.2 parts of the Radix Aucklandiae, 12 parts of Rhizoma Chuanxiongs, 12 parts of Herba Taxillis.
4, the medicine of treatment femur head necrosis according to claim 1 is characterized in that being made by following bulk drugs:
Radix Rehmanniae Preparata 20-2 part, Radix Angelicae Sinensis 20-10 part, Rhizoma Corydalis 15-5 part, Radix Achyranthis Bidentatae 16-10 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 20-10 part, Radix Salviae Miltiorrhizae 20-7 part, Radix Dipsaci 20-10 part, Rhizoma Drynariae 20-10 part, Radix Aucklandiae 4-2.5 part, Rhizoma Chuanxiong 15-5 part, Herba Taxilli 16-10 part, Radix Notoginseng 16-10 part, Borneolum Syntheticum 10-5 part, Caulis Spatholobi 20-2 part.
5,, it is characterized in that making by following bulk drugs according to the medicine of claim 1 or 4 described treatment femur head necrosiss:
17 parts of Radix Rehmanniae Preparata, 14 parts of Radix Angelicae Sinensis, 13 parts of Rhizoma Corydalis, 12 parts of Radix Achyranthis Bidentataes, 14.5 parts of Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.)s, 16 parts of Radix Salviae Miltiorrhizaes, 16 parts of Radix Dipsacis, 15 parts of Rhizoma Drynariae, 3.2 parts of the Radix Aucklandiae, 12 parts of Rhizoma Chuanxiongs, 12 parts of Herba Taxillis, 13 parts of Radix Notoginseng, 6 parts of Borneolum Syntheticums, 15 parts of Caulis Spatholobis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007100554267A CN100528194C (en) | 2007-03-11 | 2007-03-11 | Medicine for treating femoral head necrosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007100554267A CN100528194C (en) | 2007-03-11 | 2007-03-11 | Medicine for treating femoral head necrosis |
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| CN101019960A true CN101019960A (en) | 2007-08-22 |
| CN100528194C CN100528194C (en) | 2009-08-19 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB2007100554267A Expired - Fee Related CN100528194C (en) | 2007-03-11 | 2007-03-11 | Medicine for treating femoral head necrosis |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104857311A (en) * | 2015-06-12 | 2015-08-26 | 陈亚娟 | Traditional Chinese medicine for treating ischemic necrosis of femoral head |
| CN105395608A (en) * | 2015-12-30 | 2016-03-16 | 周金峰 | Traditional Chinese medicine composition for treating bone fractures and preparing method thereof |
| CN105687786A (en) * | 2016-01-22 | 2016-06-22 | 杜光辉 | Thighbone recovery soup and preparation method thereof |
| CN105983090A (en) * | 2015-05-15 | 2016-10-05 | 宋兆普 | Pills for treating femoral head necrosis |
| CN107158126A (en) * | 2017-06-14 | 2017-09-15 | 上海市普陀区人民医院 | A kind of anti-inflammatory analgetic composition |
| CN108014271A (en) * | 2017-12-11 | 2018-05-11 | 卿安华 | A kind of Chinese medicine for blood-activating and qi-promoting |
-
2007
- 2007-03-11 CN CNB2007100554267A patent/CN100528194C/en not_active Expired - Fee Related
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105983090A (en) * | 2015-05-15 | 2016-10-05 | 宋兆普 | Pills for treating femoral head necrosis |
| CN104857311A (en) * | 2015-06-12 | 2015-08-26 | 陈亚娟 | Traditional Chinese medicine for treating ischemic necrosis of femoral head |
| CN105395608A (en) * | 2015-12-30 | 2016-03-16 | 周金峰 | Traditional Chinese medicine composition for treating bone fractures and preparing method thereof |
| CN105687786A (en) * | 2016-01-22 | 2016-06-22 | 杜光辉 | Thighbone recovery soup and preparation method thereof |
| CN107158126A (en) * | 2017-06-14 | 2017-09-15 | 上海市普陀区人民医院 | A kind of anti-inflammatory analgetic composition |
| CN107158126B (en) * | 2017-06-14 | 2020-10-16 | 上海市普陀区人民医院 | Anti-inflammatory and analgesic composition |
| CN108014271A (en) * | 2017-12-11 | 2018-05-11 | 卿安华 | A kind of Chinese medicine for blood-activating and qi-promoting |
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| Publication number | Publication date |
|---|---|
| CN100528194C (en) | 2009-08-19 |
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Address after: No. 4, building 7, building 64, power transmission and distribution area, Fengman District, Jilin, Jilin Patentee after: Zhao Zhongli Address before: No. 4, building 7, building 46, power transmission and distribution area, Fengman District, Jilin, Jilin Patentee before: Zhao Zhongli |
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Granted publication date: 20090819 Termination date: 20120311 |