CN101011594A - Multifunctional nano composite plaster and method for preparing same - Google Patents

Multifunctional nano composite plaster and method for preparing same Download PDF

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Publication number
CN101011594A
CN101011594A CN 200710034293 CN200710034293A CN101011594A CN 101011594 A CN101011594 A CN 101011594A CN 200710034293 CN200710034293 CN 200710034293 CN 200710034293 A CN200710034293 A CN 200710034293A CN 101011594 A CN101011594 A CN 101011594A
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absorbed layer
medicine
nanometer silver
nano composite
woven fabrics
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张亚平
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Abstract

The invention relates to a multifunctional nanometer composite applicator, formed by base part, function part, and stripping protective layer. The base layer of base part can be one of non-woven cloth, porous PVC film or flexible fiber fabric; the function part is formed by an adsorption layer and drugs as one or the combination of haemostat, painkiller, or the like; the nanometer silver can be one of nanometer silver particles, nanometer silver gel or nanometer silver fiber fabric; the base part is adhered on the skin and flexibly fixed; the adsorption layer, drug and nanometer silver can heal the hurt organism, with promote blood circulation, anti-inflammation functions or the like. And the stripping protective layer can avoid contacting the fiber protein of organism effusion with the adsorption layer.

Description

Multifunctional nano composite plaster and preparation method
Technical field
The present invention relates to the multifunctional nano composite plaster that to treat multiple wound and infection of a kind of medical device, particularly a kind of external.
Technical background
Various wounds are in the market applied ointment or plaster; its structure is by basal layer; absorbed layer; peeling off protective layer forms; also have peeling off and establish the nanometer silver tissue layer between protective layer and the absorbed layer; change basal layer into non-woven fabrics or perforated films by medical proof fabric in addition; to improve permeability; its composition is basic identical; composition and manufacture method are single; action and function is single; the technical scheme that one nanometer silver tissue layer is set between absorbed layer and protection peel ply is disclosed as Chinese patent ZL:01259989.1; ZL:01259992.1 has announced same scheme; be respectively applied for the treatment of wound and ulcer; but but, need have (microcirculation improvement for the treatment of ulcer because of its nanometer silver anti-inflammation only; promote tissue regeneration; antiinflammatory; the acceleration ulcer healing) the medicine combined effect of multiple effect can enough make ulcer be healed.So common nanometer bandage only is fit to minor trauma and infection, and in following damage, as non-open traumatic injury, subcutaneous hemorrhage, ooze out, with red, swollen, hot, bitterly the time, need the process of alleviating pain and treatment; Open wound and for example, with hemorrhage, ooze out and dirty (sense) when dying the treatment process of needs hemostasis at once, alleviating pain and anti-inflammation; Be the Combination open wound that war wound or industrial and mineral and vehicle accident cause in addition, with fracture, hemorrhage, dirty (sense) dye, ooze out, when having an intense pain, urgent hemostasis, narcotic analgesic, shock, the wrapping of needs fixed, infection, etc. the emergency aid and treatment process; Above-mentioned all injuries are that in the market wound is applied ointment or plaster or contained nanometer silver and applies ointment or plaster and all can't satisfy the demands.Both all kinds of trauma plasters in the market only are the household supplies when handling daily microtrauma, and can not become the treatment articles for use of urgent wound, more on-the-spot emergency aid and treatment measure and medical device can not become complicated injuries in war wound, the accident time.
State key basic research development plan " 973 " project silicate-base silver nano pore composite material detects by mechanisms such as the Chinese Academy of Medical Sciences, Nat'l Pharmaceutical ﹠ Biological Products Control Institute, confirms comprising that multiple pathogenic microorganism such as antibacterial, fungus, virus, infusorian have very strong bacteriostasis and sterilization effect.Personnel introduce according to the study, and different with the antibiotic of present use, silver ion not only bactericidal effect is good, and does not have obvious drug resistance.
Summary of the invention
Purpose of the present invention just provides a kind of (series) multifunctional nano composite plaster, to satisfy the emergency aid and treatment demand of above-mentioned different occasions respectively.
Technical scheme of the present invention is achieved in that multifunctional nano composite plaster is made up of basilar part, function portion and stripping protective layer, and functional part is in the centre.It is characterized in that: basilar part is made of basal layer and not dried viscose glue, function portion is by absorbed layer, medicine and nanometer silver constitute, absorbed layer is that non-woven fabrics fabric or modification can absorb the azelon fabric, medicine (4) can comprise hemorrhage, analgesic, anesthetics, promoting blood flow and remove blood stasis drug, Percutaneous absorption enhancer, promote the ulcer healing medicine, the whole of blood vessel preparation etc. contract, several of a number class or an apoplexy due to endogenous wind or a kind of mutual compatibility, nanometer silver comprises the nanometer silver microgranule, nano silver gel, nano silver fibre fabric, stripping protective layer (6) are a kind of macromolecule thin film with holes.Function portion can be the class in above-mentioned nanometer silver and the medicine or the compatible combination of several classes; Peel off protective layer and be to preventing that damaging wound tissue exudate fibrin adheres to the porous membrane that is provided with to the adhesion of functional layer, its size is with flap coverage degree of being fully; Medicine and the interaction of nanometer silver can be used for the emergency aid and treatment of different wounds.
Owing to adopted multiple different medicine and nanometer silver fabric blending structure, make the present invention can be applicable to the demand of multiple wound respectively, the treatment of the complicated injuries that especially suitable open-air complicated injuries or industrial and mineral, vehicle accident cause.
Because the present invention has adopted the structure of directly laying viscose glue and medicine or nanometer silver on basal layer, make the present invention have and make simply, characteristics with low cost.
Because the present invention has adopted the method for laying function portion on the different base layer, make the present invention can be fit to the damage of multiple environment, be suitable for skin injury in the family as applying ointment or plaster of: nonwoven fabric base bottom, applying ointment or plaster of ventilative adhesive plaster or spandex fabric is fit to the damage of movable joint place; Applying ointment or plaster of PVC film basal layer with holes is fit to the hand wound of contact water, the emergency aid and treatment of suitable complicated injuries of spandex fabric basal layer such as industrial and mineral, vehicle accident, battlefield firearm injury.
Because with the application of laying of difference in functionality medicine, make it can be used for that the hemostasis, pain relieving, shock, anesthesia to wound, fixing, pressure dressing, absorption are oozed out, the treatment process of anti-inflammation.
Description of drawings
Fig. 1 is the basic structure sketch map of multifunctional nano composite plaster of the present invention;
Fig. 2 is the basic structure sketch map that multifunctional nano composite plaster of the present invention is used for microtrauma;
Fig. 3 is the basic structure sketch map that multifunctional nano composite plaster of the present invention is used for burn;
Fig. 4 is that multifunctional nano composite plaster of the present invention is used for the basic structure sketch map that non-opening is fallen, beats, damaged;
Fig. 5 is that multifunctional nano composite plaster of the present invention is used for the open basic structure sketch map that infects when oozing out that has than large tracts of land;
Fig. 6 is the basic structure sketch map that multifunctional nano composite plaster of the present invention is used for operative incision;
Fig. 7 is the basic structure sketch map that multifunctional nano composite plaster of the present invention is used for epidermal tissue's ulcer;
Fig. 8 is that multifunctional nano composite plaster of the present invention is used for the complicated basic structure sketch map of hindering of battlefield firearm injury, industrial and mineral and vehicle accident;
Specific embodiment
Below in conjunction with accompanying drawing specific embodiments of the invention are described in detail.
As shown in Figure 1, multifunctional nano composite plaster of the present invention is made up of basilar part, function portion, stripping protective layer; Basilar part is made of basal layer 1 and not dried viscose glue 2, and base layer material can be a kind of of non-woven fabrics, PVC film with holes or spandex fabric, and not dried viscose glue can be a kind of of pressure sensitive adhesive, thermosol, adhesive sticker; Function portion is made of jointly absorbed layer 3, curative drug 4 and nanometer silver 5, medicine 4 has: hemorrhage 4a, analgesic 4b, anesthetics 4c, activating blood circulation to dissipate blood stasis class medicine 4d, Percutaneous absorption enhancer 4e, promote ulcer healing medicine 4f, the blood vessel preparation 4g that contracts, but medicine 4 can be several all kinds of mutual compatibilities, also several or a kind of compatibility of wherein several classes or a class medicine use; Absorbed layer 3 can be that non-woven fabrics fabric or modification can absorb the azelon fabric; Hemorrhage 4a can be several mixing of medicines such as vitamin K3, etamsylate, 6-aminocaprolc acid, Radix Notoginseng, Clinopodium Polycephalum Herba Clinopodii (Herba Clinopodii Polycephali) grass, Radix Aconiti Kusnezoffii, YUNNAN BAIYAO, thrombin or wherein a kind of; Analgesic 4b can be the multiple mixing of medicines such as fentanyl, morphine, dolantin, Pericarpium Papaveris powder, Rhizoma Chuanxiong or wherein a kind of; Anesthetics 4c can be lignocaine, procaine, ovocaine, etc. the multiple mixing of medicine or wherein a kind of; Promoting blood flow and remove blood stasis drug 4d can be Oleum Terebinthinae, Flos Carthami, Flos Caryophylli, Sanguis Draxonis, JINGWANHONG cream, Flos Lonicerae, etc. the multiple mixing of medicine or wherein a kind of; Percutaneous absorption enhancer 4e can be several mixing of medicines such as dimethyl sulfoxide, 2-pyrrolidone, oleic acid, isopropyl alcohol, propylene glycol, cyclodextrin or wherein a kind of; Promote ulcer healing class medicine 4f to be: several of insulin like growth factor (IGF), growth hormone (GH), transforming growth factor (TGF), fibroblast growth factor medicines such as (FGF) or a kind of; Vasoconstriction preparation 4g can use epinephrine, ephedrine one; Nanometer silver 5 can be wherein a kind of of nanometer silver microgranule, nano silver fibre fabric, nano silver gel; Stripping protective layer 6 is a kind of macromolecule membranes with holes, adheres in order to prevent to organize in the transudate adhesion of fibrin and absorbed layer.
Specific embodiment one
As shown in Figure 2: on the basal layer 1 that constitutes by non-woven fabrics or PVC film with holes, adopt to spray or running roller basal layer 1 surface that will not dried viscose glue 2 evenly be laid in, adopt spray or methods such as high-pressure electrostatic with evenly the be laid in surface of not dried viscose glue 2 of nanometer silver 5.Also can be in advance with once injection or form after nanometer silver 5 and the not dried viscose glue 2 even blend with the running roller basal layer 1 that is laid in, lay one deck stripping protective layer 6 on its surface then.
The alternative nanometer adhesive bandage that exists in the market of the multifunctional nano composite plaster that present embodiment constitutes is applicable to family's microlesion.Have and make simply characteristics with low cost, easy to use.
Specific embodiment two
As shown in Figure 3: on the basal layer 1 that constitutes by non-woven fabrics or PVC film with holes, adopt to spray or will not dried viscose glue 2 evenly the be laid in surface of basal layer 1 of running roller method, the absorbed layer 3 that constitutes with adhesive-bonded fabric that will the be fit to the wound area size then center on not dried viscose glue 2 surfaces that is laid in is with evenly the be laid in surface of absorbed layer 3 of medicine 4 and nanometer silver 5; Also can lay one deck stripping protective layer 6 on its surface then in advance with viscose glue 2 surfaces that are laid in again after medicine 4 and nanometer silver microgranule solution 5 and the even blend infiltration of the absorbed layer 3 adhesive-bonded fabrics drying.As required, nanometer silver 5 optional nanometer silver microgranules, nano silver gel or nano silver fibre fabric are any in the present embodiment; Medicine 4 can be advocated use at the burn and scald initial stage: the water extract of Chinese medicines such as Rhizoma Polygoni Cuspidati, low elm, Cortex Ziziphi spinosae Radicis, the four seasons are clear, Radix Ilicis Pubescentis is coated on after concentrating in the absorbed layer 3 in (such Chinese medicine can reduce hinder face ooze out, promote to form a scab); There is not the burn treating that oozes out by the suitable dryness of applying ointment or plaster that nanometer silver microgranule or nanometer silver fabric are formed; Be fit to the moist treatment of scald that oozes out that has by applying ointment or plaster of forming of nano silver gel.
By the multifunctional nano composite plaster that present embodiment constitutes, can replace in the market the nanometer burn that exists and paste, simple in structure because of it, effect is single, the demand that can not satisfy multiple burn.
Specific embodiment three
As shown in Figure 4: on the basal layer 1 that constitutes by non-woven fabrics or PVC film with holes or spandex fabric, adopt and spray or will not dried viscose glue 2 evenly the be laid in surface of basal layer 1 of running roller method, the be laid in surface of viscose glue 2 of the absorbed layer 3 that adhesive-bonded fabric is constituted, the surface of the absorbed layer 3 that then medicine 4 and nanometer silver microgranule 5 evenly is laid in.Also can make medicine 4 and nanometer silver 5 microgranules attached in the non-woven fabrics fiber in advance with medicine 4 and nanometer silver microgranule 5 and the even blend of absorbed layer 3 adhesive-bonded fabrics, one deck stripping protective layer 6 be laid on its surface then in viscose glue 2 surfaces that are laid in again.In the present embodiment, different needs according to damage location, basal layer 1 can adopt a kind of of non-woven fabrics, PVC film with holes or spandex fabric, several of medicine 4 optional activating blood circulation to dissipate blood stasis class medicine 4d and pain relieving class medicine 4b two classes or a kind of mutual compatibility, and add Percutaneous absorption enhancer 4e is arranged; Concrete medicine can be referring to Fig. 1 illustrative examples; The multifunctional nano composite plaster that is made of non-woven fabrics or PVC film with holes in the present embodiment is suitable for non-joint traumatic injury treatment; By the multifunctional nano composite plaster that spandex fabric constitutes, be suitable for the traumatic injury treatment of joint.
The multifunctional nano composite plaster of present embodiment, filled up that the nanometer trauma plaster that exists in the market can not treat that the function of traumatic injury lacks as.Its alternative oral drugs absorb without stomach, intestinal tissue, and percutaneous directly absorbs, and has the advantages that effect is rapid, expense is cheap, can make things convenient for use in any environment.
Specific embodiment four
As shown in Figure 5, be to be simple pollution-free fracture, the blood vessel, neural of not accompanying from open injury disconnected and the internal organs damage---neither combined injury, as: the nano composite plaster that sharp device scuffing, pricking wound etc. use.On the basal layer 1 that constitutes by PVC with holes or spandex fabric, adopt to spray or will not dried viscose glue 2 evenly the be laid in surface of basal layer 1 of running roller method, to be laid in by the absorbed layer 3 that adhesive-bonded fabric constitutes the then surface of viscose glue 2 is evenly the be laid in surface of absorbed layer 3 of medicine 4 and nanometer silver microgranule 5.Also can be in advance with medicine 4, nanometer silver microgranule 5 and the even blend of absorbed layer 3 adhesive-bonded fabrics, make medicine 4 and nanometer silver microgranule 5 attached to after in the non-woven fabrics absorbed layer 3, be laid in the again surface of viscose glue 2, and then lay one deck stripping protective layer 6 on the surface of absorbed layer 3.In the present embodiment, according to open wound position difference, basal layer can adopt a kind of of PVC film with holes or spandex fabric; Among medicine 4 optional haemostatic medicament 4a, the analgesic drug product 4b several or wherein a kind of and nanometer silver 5 mutual compatibilities, concrete medicine can be referring to Fig. 1 illustrative examples; The multifunctional nano composite plaster that PVC film basal layer with holes constitutes is suitable for the common open tissue injury of non-joint; The multifunctional nano composite plaster that the spandex fabric basal layer constitutes is suitable for the simple open tissue injury of joint.
Specific embodiment five
As shown in Figure 6, be to sew up the composite plaster that use the back for operative incision.On the basal layer 1 that constitutes by non-woven fabrics or PVC thin film with holes, adopt to spray or will not dried viscose glue 2 evenly the be laid in surface of basal layer 1 of running roller method, to be laid in by the absorbed layer 3 that adhesive-bonded fabric constitutes the then surface of viscose glue 2 is evenly the be laid in surface of absorbed layer 3 of medicine 4 and nanometer silver microgranule 5.Also can be in advance make medicine 4 and nanometer silver microgranule 5 attached to after in the non-woven fabrics absorbed layer 3 medicine 4 and nanometer silver microgranule 5 and the even blend of absorbed layer 3 adhesive-bonded fabrics, be laid in the again surface of viscose glue 2, and then lay one deck stripping protective layer 6 on the surface of absorbed layer 3.In the present embodiment, according to the different parts of operative incision, basal layer 1 can adopt a kind of of PVC film with holes or spandex fabric; Two kinds or the wherein a kind of and nanometer silver 5 mutual compatibilities of medicine 4 optional analgesic 4b, transdermal absorption accelerator 4e; The multifunctional nano composite plaster that PVC film basal layer with holes constitutes is suitable for the bandaging method for treating of non-joint operative incision; The multifunctional nano composite plaster that the spandex fabric basal layer constitutes is suitable for the bandaging method for treating of the operative incision of joint.
Specific embodiment six
As shown in Figure 7, be to aim at the composite plaster that treatment epidermal tissue ulcer is used.On the basal layer 1 that constitutes by non-woven fabrics or PVC thin film with holes, adopt to spray or will not dried viscose glue 2 evenly the be laid in surface of basal layer 1 of running roller, to be laid in by the absorbed layer 3 that adhesive-bonded fabric constitutes the then surface of viscose glue 2 is evenly the be laid in surface of absorbed layer 3 of medicine 4 and nanometer silver microgranule 5.Also can be in advance make medicine 4 and nanometer silver microgranule 5 attached to after in the non-woven fabrics absorbed layer 3 medicine 4 and nanometer silver microgranule 5 and the even blend of absorbed layer 3 adhesive-bonded fabrics, be laid in the again surface of viscose glue 2, and then lay one deck stripping protective layer 6 on the surface of absorbed layer 3.In the present embodiment, according to the difference of ulcer happening part, basal layer 1 can adopt a kind of of non-woven fabrics or PVC film with holes; The medicine of medicine 4 optional promotion ulcer healings such as insulin 4f; Nanometer silver 5 can be selected a kind of of nanometer silver microgranule and nano silver gel, and the multifunctional nano composite plaster that is made of PVC film basal layer 1 with holes is suitable for the treatment of non-joint ulcer, and waterproof; The multifunctional nano composite plaster that is made of spandex fabric basal layer 1 is suitable for the treatment of movable joint place ulcer.
Specific embodiment seven
As shown in Figure 8, be the multifunctional nano composite plaster that aims at the complicated injuries design that battlefield firearm injury, industrial and mineral and vehicle accident cause.Adopt to spray or will not dried viscose glue 2 evenly the be laid in surface of the basal layer 1 that constitutes by spandex fabric of running roller method, to be laid in by the absorbed layer 3 that adhesive-bonded fabric constitutes the then surface center of viscose glue 2 is evenly the be laid in surface of absorbed layer 3 of medicine 4 and nanometer silver 5.Also can be in advance make medicine 4 and nanometer silver 5 attached to after in the non-woven fabrics absorbed layer 3 medicine 4 and nanometer silver 5 and the even blend of absorbed layer 3 adhesive-bonded fabrics, be applied to the surface of viscose glue 2 again, and then lay one deck stripping protective layer 6 on the surface of absorbed layer 3.In the present embodiment, difference according to the complicated injuries position, medicine 4 can be selected each and nanometer silver 5 mutual compatibilities of whole among hemorrhage 4a, analgesic 4b, anesthetics 4c, vasoconstrictor 4g, the Percutaneous absorption enhancer 4e or number classes for use, and specifically medicine can be referring to Fig. 1 illustrative examples; Nanometer silver 5 can be nanometer silver microgranule or nano silver gel; The basal layer 1 of spandex fabric wants enough big, can cover whole wound site, and spacious and comfortable spandex fabric 1 is arranged as the wrapping fixing tape.
On-the-spot emergency aid and treatment when the multifunctional nano composite plaster of present embodiment is suitable for complicated injuries, as: emergency aid and treatment processes such as the hemostasis of fracture fixation, site of injury, pain relieving, anesthesia, shock, infection.It filled up domestic in the complicated injuries disposal process the insufficient phenomenon of equipment, the solution because of the emergency aid and treatment of field first aid article and first-aid equipment scarcity also is provided in above-mentioned complicated injures and deaths, accident.
Owing to adopted the basal layer of multiple gas permeable material, make multifunctional nano composite plaster of the present invention can be used for the different parts or the joint of body, and have ventilative, waterproof, do not influence the characteristics of joint motions.
Owing to adopted the mutual compatibility of multiple medicine and nanometer silver to use, make multifunctional nano composite plaster of the present invention can be used for multiplely multi-form falling, beat, decrease, when dampening with subcutaneous hemorrhage ooze out, the wound emergency aid and treatment of red, swollen, hot, bitterly complicated occasions such as simple sexual trauma, open wound, operation stitching otch, epidermal tissue's ulcer, burn and fracture fixation.Become in multiple wound environment the emergency aid and treatment measure and the equipment of the very first time first-selection during open-air the injury.Have use simple and direct, reliable for effect, powerful, can be and save the wounded's life from damage, further implement after the institute treatment and striven for the time and create conditions.

Claims (8)

1, a kind of multifunctional nano composite plaster, by basilar part, function portion and stripping protective layer are formed jointly, it is characterized in that: basilar part is made of basal layer (1) and not dried viscose glue (2), function portion is by absorbed layer (3), medicine (4) and nanometer silver (5) constitute, absorbed layer (3) can absorb the azelon fabric for non-woven fabrics fabric or modification, medicine (4) can comprise hemorrhage (4a), analgesic (4b), anesthetics (4c), promoting blood flow and remove blood stasis drug (4d), Percutaneous absorption enhancer (4e), promote ulcer healing medicine (4f), the whole of blood vessel preparation (4g) etc. contract, several of a number class or an apoplexy due to endogenous wind or a kind of mutual compatibility, nanometer silver (5) comprises the nanometer silver microgranule, nano silver gel, the nano silver fibre fabric.
2, multifunctional nano composite plaster according to claim 1 is characterized in that: basal layer (1) but non-woven fabrics, PVC thin film with holes or spandex fabric a kind of.
3, multifunctional nano composite plaster according to claim 1, it is characterized in that: the hemorrhage (4a) in the medicine (4): vitamin K3, etamsylate, 6-aminocaprolc acid, Radix Notoginseng, Clinopodium Polycephalum Herba Clinopodii (Herba Clinopodii Polycephali) grass, Radix Aconiti Kusnezoffii, YUNNAN BAIYAO, several of thrombin or a kind of, analgesic (4b) is: fentanyl, morphine, dolantin, the Pericarpium Papaveris powder, several of Rhizoma Chuanxiong etc. or a kind of, anesthetics (4c) is: lignocaine, procaine, several of ovocaine or a kind of, promoting blood flow and remove blood stasis drug (4d) but Oleum Terebinthinae, Flos Carthami, Flos Caryophylli, Sanguis Draxonis, JINGWANHONG cream, several of Flos Lonicerae or a kind of, Percutaneous absorption enhancer (4e) is: dimethyl sulfoxide, the 2-pyrrolidone, oleic acid, isopropyl alcohol, propylene glycol, several of cyclodextrin or a kind of, promote ulcer healing class medicine 4f: insulin like growth factor (IGF), growth hormone (GH), transforming growth factor (TGF), several of fibroblast growth factor (FGF) or a kind of, vasoconstriction preparation (4g) but epinephrine or ephedrine a kind of.
4, multifunctional nano composite plaster according to claim 1, it is characterized in that: medicine (4) can be in advance absorbed layer (3) mixed together of different pharmaceutical (4) solution and non-woven fabrics formation to be soaked into kneading with combining of absorbed layer (3), dehydrate is made then, also different medicines (4) solution is painted on absorbed layer (3) surface that non-woven fabrics constitutes, drying is made then.
5, multifunctional nano composite plaster according to claim 1 is characterized in that: nanometer silver (5) can be the wherein a kind of of nanometer silver microgranule, nano silver fibre fabric or nano silver gel.
6, multifunctional nano composite plaster according to claim 1, it is characterized in that: nanometer silver (5) can be in advance nanometer silver (5) to be soaked into kneading with absorbed layer (3) mixed together that non-woven fabrics constitutes with combining of absorbed layer (3), oven dry comb is whole then makes, and also the surperficial drying of absorbed layer (3) that nanometer silver (5) solution is painted on the non-woven fabrics formation is made.
7, multifunctional nano composite plaster according to claim 1, it is characterized in that: Percutaneous absorption enhancer (4e) can be in advance the same absorbed layer of Percutaneous absorption enhancer (4e) (3) mixed together to be soaked into kneading with combining of absorbed layer (3), oven dry comb is whole then makes, and also the surperficial drying of absorbed layer (3) that Percutaneous absorption enhancer (4e) solution is painted on the non-woven fabrics formation is made.
8, multifunctional nano composite plaster according to claim 1, it is characterized in that: promote that ulcer healing medicine (4f) and combining of absorbed layer (3) can be in advance promoting ulcer healing medicine (4f) to soak into kneading with absorbed layer (3) mixed together that non-woven fabrics constitutes, whole making is combed in oven dry then, also the surperficial drying of absorbed layer (3) that promotes ulcer healing medicine (4f) solution to be painted on the non-woven fabrics formation is made.
CN 200710034293 2007-01-23 2007-01-23 Multifunctional nano composite plaster and method for preparing same Pending CN101011594A (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101804218A (en) * 2010-04-13 2010-08-18 王艳 Human-body absorbable trauma dressing containing Yunnan white drug powder or Yunnan white drug powder extractive
CN101584877B (en) * 2009-06-15 2012-11-21 于向英 Packed medicament plaster for laparoscopic surgery
CN103006699A (en) * 2012-01-29 2013-04-03 中国人民解放军第四军医大学 Compound medicament with double effects of alleviating pain and inhibiting bacteria
CN104107108A (en) * 2014-06-23 2014-10-22 江美珍 Adhesive bandage capable of achieving sterilization function by means of calamint
CN104587515A (en) * 2013-11-01 2015-05-06 上海交通大学医学院附属第九人民医院 Medical wound dressing with anti-infection function
CN109529022A (en) * 2019-01-05 2019-03-29 江苏美德愈医疗科技有限公司 A kind of diabetic foot wound externally applied drug and its application method
CN111455557A (en) * 2019-01-20 2020-07-28 泽塔纳米科技(苏州)有限公司 Antibacterial nanofiber membrane and preparation method thereof
CN111481733A (en) * 2020-04-22 2020-08-04 卢丽菊 Biological medicine wound surface dressing

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101584877B (en) * 2009-06-15 2012-11-21 于向英 Packed medicament plaster for laparoscopic surgery
CN101804218A (en) * 2010-04-13 2010-08-18 王艳 Human-body absorbable trauma dressing containing Yunnan white drug powder or Yunnan white drug powder extractive
CN103006699A (en) * 2012-01-29 2013-04-03 中国人民解放军第四军医大学 Compound medicament with double effects of alleviating pain and inhibiting bacteria
CN104587515A (en) * 2013-11-01 2015-05-06 上海交通大学医学院附属第九人民医院 Medical wound dressing with anti-infection function
CN104107108A (en) * 2014-06-23 2014-10-22 江美珍 Adhesive bandage capable of achieving sterilization function by means of calamint
CN104107108B (en) * 2014-06-23 2016-06-08 江美珍 A kind of bandage utilizing Manyhead Clinopodium Herb sterilization
CN109529022A (en) * 2019-01-05 2019-03-29 江苏美德愈医疗科技有限公司 A kind of diabetic foot wound externally applied drug and its application method
CN111455557A (en) * 2019-01-20 2020-07-28 泽塔纳米科技(苏州)有限公司 Antibacterial nanofiber membrane and preparation method thereof
CN111481733A (en) * 2020-04-22 2020-08-04 卢丽菊 Biological medicine wound surface dressing
CN111481733B (en) * 2020-04-22 2022-04-26 欣乐加生物科技温州有限公司 Biological medicine wound surface dressing

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