CN101001652A - 生产皮肤替代物的交联胶原基质 - Google Patents

生产皮肤替代物的交联胶原基质 Download PDF

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Publication number
CN101001652A
CN101001652A CNA2005800273347A CN200580027334A CN101001652A CN 101001652 A CN101001652 A CN 101001652A CN A2005800273347 A CNA2005800273347 A CN A2005800273347A CN 200580027334 A CN200580027334 A CN 200580027334A CN 101001652 A CN101001652 A CN 101001652A
Authority
CN
China
Prior art keywords
collagen
matrix
skin
substitute
fibroblasts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2005800273347A
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English (en)
Chinese (zh)
Inventor
奥古斯特·贝恩德
沃尔夫冈·弗里斯
卡斯滕·鲁迪格·梅韦斯
马丁纳·劳斯
亨利埃特·本茨
斯特凡·基彭伯格
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phenion GmbH and Co KG
Original Assignee
Phenion GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phenion GmbH and Co KG filed Critical Phenion GmbH and Co KG
Publication of CN101001652A publication Critical patent/CN101001652A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cosmetics (AREA)
CNA2005800273347A 2004-08-13 2005-08-05 生产皮肤替代物的交联胶原基质 Pending CN101001652A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004039537.3 2004-08-13
DE102004039537A DE102004039537A1 (de) 2004-08-13 2004-08-13 Vernetzte Kollagenmatrix zur Herstellung eines Hautäquivalentes

Publications (1)

Publication Number Publication Date
CN101001652A true CN101001652A (zh) 2007-07-18

Family

ID=35677672

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2005800273347A Pending CN101001652A (zh) 2004-08-13 2005-08-05 生产皮肤替代物的交联胶原基质

Country Status (7)

Country Link
US (1) US20070269792A1 (enExample)
EP (1) EP1778307B1 (enExample)
JP (1) JP2008508968A (enExample)
CN (1) CN101001652A (enExample)
AT (1) ATE460950T1 (enExample)
DE (2) DE102004039537A1 (enExample)
WO (1) WO2006018147A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114258428A (zh) * 2019-09-17 2022-03-29 凸版印刷株式会社 细胞结构体及其制造方法

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006006461A1 (de) * 2006-02-10 2007-08-23 Phenion Gmbh & Co. Kg Hautmodell mit dendritischen Zellen
US8709081B2 (en) 2006-10-23 2014-04-29 Stemedica Cell Technologies, Inc. Cellular scaffold
US8105380B2 (en) 2006-10-23 2012-01-31 Stemedica Cell Technologies, Inc. Cellular scaffold
DE102007044093A1 (de) 2007-09-14 2009-03-19 Phenion Gmbh & Co. Kg Nukleinsäurehaltige kosmetische und/oder pharmazeutische Zubereitungen zur Induktion antimikrobieller Peptide in epithelialen Deckgeweben
FR2957089A1 (fr) * 2010-03-05 2011-09-09 Immunosearch Methode d'evaluation du potentiel sensibilisant d'un compose test
JP5595164B2 (ja) * 2010-07-30 2014-09-24 株式会社 資生堂 真皮黄色化の評価モデル
US8722854B2 (en) 2010-12-23 2014-05-13 Medskin Solutions Dr. Suwelack Ag Degradation-stabilised, biocompatible collagen matrices
DE102012223061A1 (de) 2012-12-13 2014-06-18 Henkel Ag & Co. Kgaa Altershautmodell
WO2015166455A1 (en) 2014-04-30 2015-11-05 Fondazione Istituto Italiano Di Tecnologia Method for producing a totally endogenous bioengineered tissue and tissue obtained thereby
JP6654323B2 (ja) * 2014-11-04 2020-02-26 昌和 栗田 重層上皮組織形成能を有する細胞、及びその製造方法
CN105087381A (zh) * 2015-08-28 2015-11-25 深圳爱生再生医学科技有限公司 3d免疫细胞培养支架及其制备方法
KR20170055791A (ko) * 2015-11-12 2017-05-22 한국과학기술연구원 인 비트로 3ｄ 피부 진피 모델 및 그를 사용하여 약물을 스크리닝하는 방법
JP2017112998A (ja) * 2015-12-18 2017-06-29 富士フイルム株式会社 細胞積層体、生体移植材料、表皮の分化状態の評価方法及び細胞積層体の製造方法、並びにインスリン様成長因子−１産生促進剤
DE102016206862A1 (de) 2016-04-22 2017-10-26 Henkel Ag & Co. Kgaa In-vitro Vollhautmodell, enthaltend dreidimensionale Zellkulturmodelle der Schweißdrüse
US20220016321A1 (en) * 2018-12-13 2022-01-20 Ohio State Innovation Foundation Dermal substitutes and engineered skin with rete ridges
DE102019135193B4 (de) * 2019-12-19 2022-02-03 Henkel Ag & Co. Kgaa Gewebetechnologisch unterstützte Rekonstruktion einer ekkrinen Schweißdrüse
WO2022056131A2 (en) * 2020-09-11 2022-03-17 The Trustees Of Columbia University In The City Of New York Wearable engineered human skin and systems and methods for making the same
CN113201481B (zh) * 2021-04-19 2023-10-13 清华大学深圳国际研究生院 皮肤微球及其制备方法和应用

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Publication number Priority date Publication date Assignee Title
US4925924A (en) * 1984-03-27 1990-05-15 University Of Medicine And Dentistry Of New Jersey Biocompatible synthetic and collagen compositions having a dual-type porosity for treatment of wounds and pressure ulcers and therapeutic methods thereof
ATE161408T1 (de) * 1990-04-24 1998-01-15 Mark Eisenberg Zusammengesetztes äquivalent der lebenden haut
CA2119064A1 (en) * 1993-03-17 1994-09-18 Richard A. Berg Dermal-epidermal in vitro test system
JP2858087B2 (ja) * 1994-09-19 1999-02-17 グンゼ株式会社 組織培養用基材及び組織培養法
US5658190A (en) * 1995-12-15 1997-08-19 Micron Technology, Inc. Apparatus for separating wafers from polishing pads used in chemical-mechanical planarization of semiconductor wafers
FR2743817B1 (fr) * 1996-01-23 1998-03-13 Oreal Equivalent de peau comprenant des cellules de langerhans
US5963489A (en) * 1998-03-24 1999-10-05 International Business Machines Corporation Method and apparatus for redundancy word line replacement in a repairable semiconductor memory device
JP2000125855A (ja) * 1998-10-21 2000-05-09 Gunze Ltd 人工皮膚
FR2809313B1 (fr) * 2000-05-26 2005-11-18 Coletica Procedes de preparation de nouveaux supports a base de collagene pour l'ingenieurie tissulaire et biomateriaux obtenus
CA2410956C (en) * 2000-05-31 2012-12-04 Michaela Noll Three-dimensional skin model
US6974697B2 (en) * 2001-03-02 2005-12-13 Stratech Corporation Skin substitutes with improved barrier function
US7741116B2 (en) * 2002-03-06 2010-06-22 University Of Cincinnati Surgical device for skin therapy or testing

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114258428A (zh) * 2019-09-17 2022-03-29 凸版印刷株式会社 细胞结构体及其制造方法

Also Published As

Publication number Publication date
DE502005009240D1 (de) 2010-04-29
WO2006018147A2 (de) 2006-02-23
DE102004039537A1 (de) 2006-02-23
ATE460950T1 (de) 2010-04-15
US20070269792A1 (en) 2007-11-22
EP1778307A2 (de) 2007-05-02
JP2008508968A (ja) 2008-03-27
EP1778307B1 (de) 2010-03-17
WO2006018147A3 (de) 2006-06-15

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