CN100998330A - Compound insecticide containing fipronil and Etrofolan - Google Patents
Compound insecticide containing fipronil and Etrofolan Download PDFInfo
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Abstract
A composite insecticide instead of the high-poison organophosphorus insecticide for the rice borer, plant hopper, leafhopper, etc is composed of fipronil and isoprocarb in weight ratio of 1: (0.1-75).
Description
Technical field
The present invention relates to technical field of pesticide, the Pesticidal combination of particularly a kind of fluorine-containing worm nitrile and Mobucin, said composition has efficient, safe insecticidal activity, can be effectively applied to prevent and treat insects such as rice borer insects, plant hopper, leafhopper class.
Background technology
Along with the raising of the mankind to food and environmental requirement, the reduction of high malicious organophosphorus insecticide kind has become the key subjects of China's pesticide industry, and the great market space has been vacateed in eliminating of the contour drugs kind of picture acephatemet, and wishing has efficient, safe insecticide variety to act during a vacancy.Because China's initiative agricultural chemicals is at the early-stage, the new pesticides with independent intellectual property right can't be satisfied the demand, and therefore, it is the task of top priority that the composite kind of development of new is used to replace high malicious organic phosphor kind.
In the control rice grub,, be sought after researching and developing specific pesticide targetedly because migratory pest easily breaks out and causes disaster.Existing acephatemet uses existing quite long history as the paddy field insecticide of low price, has brought into play important function over a period to come.But along with China high-toxic pesticide kind is cut down the enforcement of plan, aspect the preventing and treating of paddy field insect, be badly in need of efficient, safety, valency low, with eco-friendly insecticide new varieties.
Fluorine worm nitrile (Chinese common name), chemical name: 5-amino-1-(2,6-dichlor-4-trifluoromethyl phenyl)-4-trifluoromethyl sulfinyl pyrazole-3-nitrile, English common name: fipronil is the Insecticidal pyrazolines of agriculture and garden field extensive use.Fluorine worm nitrile is a broad spectrum insecticide, rice borer insects (comprising striped rice borer, rice leaf roller, paddy stem borer, pink rice borer etc.), plant hopper (comprising small brown rice planthopper, brown planthopper, white-backed planthopper etc.) etc. all there is good preventive effect, but the use of single medicament can strengthen the medicament selection pressure, pest is developed immunity to drugs, the thing followed be exactly drug effect reduce or prevent and treat invalid.
Mobucin (Chinese common name), chemical name: the o-isopropyl phenyl methyl carbamate, English common name: isoprocarb belongs to carbamate insecticide.Mobucin has good preventive effect to rice fulgorid, leafhopper etc., and quick-acting is strong, and adult is had special efficacy, but rice fulgorid takes place the heavy time, and is single with the difficult effectively control of Mobucin harm.
Process has 26 relevant patents open, as table 1 to the Chinese invention patent retrieval (on 01 13rd, 2007) of the Pesticidal combination of fluorine-containing worm nitrile.
The Chinese invention patent result for retrieval of the Pesticidal combination of the fluorine-containing worm nitrile of table 1
| Sequence number | Application number | Denomination of invention | The composition content |
| 1 | 02133827.2 | Fipronil-nimbin emulsion and preparation method thereof | Fluorine worm nitrile and nimbin |
| 2 | 200410033503.5 | Nimbin and fluorine worm nitrile mixed insecticide preparation | Fluorine worm nitrile and nimbin |
| 3 | 03139960.6 | Rotenone and fluorine worm nitrile suspending agent and preparation method thereof | Fluorine worm nitrile and rotenone |
| 4 | 01128417.X | Biochemical composite pesticide | Fluorine worm nitrile and bacillus thuringiensis,Bt |
| 5 | 99114204.7 | A kind of Recompounded pesticide | Fluorine worm nitrile and jinggangmycin |
| 6 | 03124407.6 | Efficiently, compound pesticide of low toxicity | Fluorine worm nitrile and orthene, Hostathion, dichlorvos |
| 7 | 98115768.8 | Firponil compounded pesticide | Fluorine worm nitrile and chlorophos, second first, cartap |
| 8 | 200410016947.8 | Firponil compounded pesticide | Fluorine worm nitrile and diazinon, phenthoate dimephenthoate cidial |
| 9 | 200410016946.3 | A kind of Firponil compounded pesticide | Fluorine worm nitrile and sumithion, ethion |
| 10 | 00112181.2 | Fluorine nitrile enemy's missible oil and production technology thereof | Fluorine worm nitrile and chlorophos |
| 11 | 00112280.0 | The insecticide of energy preventing and killing rice gall insect | Fluorine worm nitrile and chlopyrifos |
| 12 | 200310100529.2 | The insecticide of preventing and killing rice gall insect | Fluorine worm nitrile and chlopyrifos |
| 13 | 200610018141.1 | A kind of insecticides | Fluorine worm nitrile and chlopyrifos |
| 14 | 99114445.7 | Triazole fluorine nitrile cream pesticide and manufacture method thereof | Fluorine worm nitrile and Hostathion |
| 15 | 200510041409.9 | Fluorine worm nitrile and pyridaphethione Recompounded pesticide | Fluorine worm nitrile and pyridaphethione |
| 16 | 200610049126.3 | A kind of Firponil compounded pesticide | Fluorine worm nitrile and Profenofos |
| 17 | 200610049125.9 | Firponil compounded pesticide | Fluorine worm nitrile and malathion |
| 18 | 02130761.X | The Pesticidal combination that contains fluorine worm nitrile and dimehypo | Fluorine worm nitrile and dimehypo |
| 19 | 200510031365.1 | Double fipronil compound micellar emulsion insecticide | Fluorine worm nitrile and dimehypo |
| 20 | 03102807.1 | A kind of Firponil compounded pesticide | Fluorine worm nitrile and desinsection list |
| 21 | 200510060438.X | Fluorine worm nitrile and fenobucarb composite pesticide | Fluorine worm nitrile and Bassa |
| 22 | 200410014033.8 | Composition and the application aspect control agriculture and garden various pests thereof with insecticidal activity | Fluorine worm nitrile and furans worm hydrazides |
| 23 | 01138074.8 | A kind of dressing agent for rice of pest control | Fluorine worm nitrile and Imidacloprid |
| 24 | 00112689.X | The insecticide of control eliminating pests including rice stem maggot | Fluorine worm nitrile and Imidacloprid |
| 25 | 200510132849.5 | A kind of composition pesticide of killing the worm mite and preparation method thereof | Fluorine worm nitrile and Avermectins |
| 26 | 200510059055.0 | The complex insecticidal composition of fluorine-containing worm nitrile | Fluorine worm nitrile and gamma cyhalothrin, fenpropathrin, cycloprothrin, esfenvalerate, ether chrysanthemum ester and silafluofene, chlorpyrifos-methyl, Bassa, one of Acetamiprid and chlorine methamidophos |
Analyze the Pesticidal combination of above-mentioned fluorine-containing worm nitrile, do not see the Pesticidal combination of fluorine worm nitrile and Mobucin.
Because the paddy growth cycle is long; insects such as striped rice borer, rice leaf roller, rice fulgorid usually can be taken place the same period; and the agricultural chemicals of also often some being prevented and treated different objects in the agricultural production mixes use; be to have saved manually on the one hand; also too much medicament is spilt to the field but then, occur using with situations such as improper sometimes.Therefore, from environmental protection, safety, economic dispatch angle, the exploitation synergy is that the compounded combination of synergy is very necessary.
Summary of the invention
The invention provides the Pesticidal combination of a kind of fluorine-containing worm nitrile and Mobucin, its objective is and to cut down under the background of implementing plan in China's high-toxic pesticide kind, develop a kind of environment-friendly type of high malicious organic phosphor kind, high performance novel built insecticide of replacing, the compound drug of function admirable and safety is provided for important rice grubs such as control rice-stem borer, leaf-roller, rice fulgorids.
For achieving the above object, the technical solution used in the present invention is: the Pesticidal combination of a kind of fluorine-containing worm nitrile and Mobucin, and effective active components comprises:
A component chemical name: 5-amino-1-(2,6-dichlor-4-trifluoromethyl phenyl)-4-trifluoromethyl sulfinyl pyrazole-3-nitrile, Chinese common name: " fluorine worm nitrile ";
B component chemical name: o-isopropyl phenyl methyl carbamate, Chinese common name: " Mobucin ";
The weight proportion of A component and B component is 1: 0.1～75.
Related content in the technique scheme is explained as follows:
1, about the characteristic analysis of fluorine worm nitrile, Mobucin
(1) fluorine worm nitrile
Fluorine worm nitrile has one of effective ingredient of Insecticidally-active composition as the present invention, have desinsection wide spectrum, efficient, and the mechanism of action uniqueness is to hinder the chloride metabolism of insect γ-An Jidingsuan control, belongs to GABA-chloride channel inhibitor.Fluorine worm nitrile have tag, stomach toxicity and moderate systemic action.Soil insect can be prevented and treated, insect on the ground can be prevented and treated again; Both can be used for cauline leaf and handled and soil treatment, can be used for seed treatment again.Be used to prevent and treat insects such as paddy rice, corn, cotton, banana, beet, potato, fields of peanut and other crops aphid, leafhopper, lepidopterous larvae, fly class and coleoptera.
In Rice Production practice, fluorine worm nitrile can be controlled the harm of snout moth's larva class pests such as rice-stem borer, rice leaf roller effectively, takes place when serious rice fulgorid, and the peasant also prevents and treats plant hopper with fluorine worm nitrile, and certain effect is also arranged.
(2) Mobucin
Mobucin has one of the effective ingredient of the composition of insecticidal activity as the present invention, have stomach toxicity, tag and fumigation action, in entering insect bodies after, can suppress cholinesterase activity, cause the insect paralysis to dead.Insects such as rice fulgorid, leafhopper class are had special efficacy, and the power of knocking down is strong, and drug effect is rapid but the lasting period is short, generally has only 3～5 days.
2, the synergy of fluorine worm nitrile and Mobucin is remarkable synergistic effect
(1) when the medicament of research screening control rice-stem borer, leaf-roller and brown planthopper, finds that fluorine worm nitrile all has good indoor activity to striped rice borer, leaf-roller, brown planthopper nymph and adult.The indoor virulence of rice seedling feeding method test to striped rice borer, LC are soaked in employing
50Be 0.0184mgL
-1, with Hostathion (LC
50Be 64.5857mgL
-1) being the contrast medicament, the relative virus force index of fluorine worm nitrile is 351000.09, exceeds 4 orders of magnitude than Hostathion, belongs to the super-high-efficient medicament, is applicable to field control striped rice borer, rice leaf roller.
(2) when the medicament of research screening control brown planthopper, employing rice seedling infusion process has been tested the indoor virulence to the nymph of brown planthopper respectively, and the result shows: with Imidacloprid (LC
50Be 0.9300mgL
-1) being the contrast medicament, fluorine worm nitrile and Mobucin are to the LC of nymph
50Be respectively 0.7418 and 47.0549mgL
-1, relative virus force index is respectively 125.50 and 1.98, and fluorine worm nitrile is to high 2 orders of magnitude of specific activity Mobucin of brown planthopper.Fluorine worm nitrile and Mobucin all can be used for preventing and treating brown planthopper in the actual production.Insecticide fluorine worm nitrile is better than activity to adult to the activity of nymph, and the lasting period is long.The insecticide Mobucin is better than activity to nymph to the activity of brown planthopper adult, and Mobucin has and knock down activity fast, and quick-acting is strong.Both are action compensating when the control plant hopper, and are suitable composite especially.
(3) when the synergy of research fluorine worm nitrile and Mobucin, fixedly fluorine worm nitrile is 1 part, the umber of Mobucin from 0.01 to 100 o'clock, and the synergistic effect value is 1.50～19.00, synergy performance addition or synergy.When the proportioning of fluorine worm nitrile and Mobucin is 1: 0.1～75, find that fluorine worm nitrile and Mobucin all have synergistic effect to brown planthopper, co-toxicity coefficient is 125.00～337.14, synergistic effect is remarkable.
Based on above-mentioned result of study, the inventor claims and protects the Pesticidal combination that contains fluorine worm nitrile and Mobucin.Said composition can be used to prevent and treat insects such as the snout moth's larva of rice, plant hopper, leafhopper class effectively.Fluorine-containing worm nitrile and Mobucin have an Insecticidally-active composition, total deal of each effective ingredient and certain amount of solvent or auxiliary agent or filler should be 100%, wherein, the preferable range of the weight proportion of A component fluorine worm nitrile and B component Mobucin is 1: 1～75.
3, the Pesticidal combination of fluorine-containing worm nitrile and Mobucin can be developed to environment-friendly type, high performance novel formulation
As research object striped rice borer and the rice fulgorid of pest of the present invention, all be that paddy field takes place by frequent and serious insect.Striped rice borer can be represented the snout moth's larva class pest, have to bore the moth property, to the requirement height of insecticide, medicament preferably have tag, stomach toxicity, interior suction and Penetration Signature.The rice fulgorid kind is many, comprises brown planthopper, white-backed planthopper, small brown rice planthopper etc., to the medicament of preventing and treating rice fulgorid long lasting effect must be arranged.Since fluorine worm nitrile have tag, stomach toxicity and moderate systemic action, and Mobucin has stomach toxicity, tags and fumigation action, is that preparation stability is qualified to the requirement of preparation, strong to the adhesion plate-out ability of plant or insect, the infiltration conductivity is good.In conjunction with the characteristics of fluorine worm nitrile and the former medicine of Mobucin, novel formulation can be made water dispersible granules or formulations such as suspending agent or aqueous emulsion or wetting powder or missible oil.
When adopting the present invention to have the preparation of compositions insecticide of insecticidal activity, can be with fluorine worm nitrile, Mobucin and appropriate carriers and additive, as mixing such as emulsifier, dispersant, stabilizing agent, bleeding agents, make water dispersion granule, suspending agent, aqueous emulsion, wetting powder or missible oil etc. by common method.Being adapted at the present invention, to have the carrier that uses in the composition of insecticidal activity can be any solid or the liquid-carrier that is generally used for the agriculture and garden medicament, as required, can use various surfactants, stabilizing agent and other auxiliary composition.In the preparation of commerce usefulness, composition of the present invention can also mix (for example various insecticides, miticide, bactericide, weed killer herbicide, plant growth regulator, synergist, fertilizer, aromatic) with other active ingredient, to expand its practicality.
4, the Pesticidal combination of fluorine-containing worm nitrile of the present invention and Mobucin can effectively be prevented and treated various pests such as rice-stem borer, rice leaf roller, paddy stem borer, pink rice borer, small brown rice planthopper, brown planthopper, white-backed planthopper, leafhopper, when control paddy rice migratory pest rice leaf roller, brown planthopper, be one of preferably efficient, quick-acting medicaments.In addition, Pesticidal combination of the present invention also can be prevented and treated rice thrips, Lissorhoptrus oryzophilus Kuschel, the rice gall midge of paddy rice aspect simultaneously; Thorny insect on the important agricultural crops such as control fruit tree, vegetables, tea tree, gardening eats into moth, lyonetid, bitter edible plant looper, fleahopper, leafhopper, thrips, various aphid, chrysomelid, aleyrodid etc. as beet armyworm, prodenia litura, tomato moth, imported cabbageworm, leaf roller, fruit.
Though the amount of application of Pesticidal combination of the present invention needs to adjust according to the kind of essential condition such as population density, core crop and cropping pattern, weather condition, method of application etc., but generally speaking, the total amount that per hectare is used is 0.1～1000g, preferably 1～500g.In practice, when Pesticidal combination of the present invention is water-dispersible granule, suspending agent, aqueous emulsion, wetting powder, missible oil etc., can impose on crop and the pest after the effective ingredient consumption dilution by correspondence.
Because the technique scheme utilization, the present invention has following advantage and effect:
1, the Pesticidal combination of fluorine-containing worm nitrile of the present invention and Mobucin is compared not only with single fluorine worm nitrile or Mobucin and is had significant synergies, and be a kind of environment-friendly type of high malicious organic phosphor kind, high performance novel built insecticide of replacing, the compound drug of function admirable and safety is provided for important rice grubs such as control rice-stem borer, leaf-roller, rice fulgorids.
2, research and develop a pesticide species and need the cycle in 8～10 years with good market value, and the economic life cycle of a good kind should be not less than 10 years, and the medication of Chinese farmers custom is: not at all easy medicine that found, just found and do not put, do not considered the drug-fast problem that fully utilizes.Because the use of single medicament can strengthen the medicament selection pressure, pest is developed immunity to drugs, the thing followed be exactly drug effect reduce or prevent and treat invalid.Therefore, from the angle of this outstanding kind of protection fluorine worm nitrile, the complex preparation of exploitation fluorine worm nitrile has science, helps protecting the economic life of fluorine worm nitrile kind, reduces single agent consumption, alleviates the medicament selection pressure, suspension of pesticide resistance generation or development.
3, owing to rice leaf folder, rice fulgorid all are migratory pests, to prevent and treat quick-acting in order promoting, in time to force down the radix of causing harm in the phase that flies into, the harm of controlling migratory pest fast is crucial.Because Mobucin has the wholesomeness of knocking down fast to the plant hopper adult, be suitable so select fluorine worm nitrile and Mobucin composite.
4, the present invention can reach the double purpose of controlling when causing harm the same periods such as snout moth's larva class, plant hopper, leafhopper class, saves labour turnover; Use with simple the edge of a field simultaneously and compare, reduced dosing, reduced agricultural basis.
5, in the past in agricultural production practice, prevent and treat insects such as the snout moth's larva of rice, plant hopper, leafhopper with the contour malicious organic phosphor of acephatemet, although it is cost is low, dangerous.Along with the forbidding of country to the malicious organic phosphor of height, the demand that environmentally friendly type new varieties are prevented and treated rice grub is very big, realizes very big space is provided for the market of complex preparation of the present invention, has good market prospects.
6, the compounded combination of fluorine-containing worm nitrile of the present invention and Mobucin is compared with fluorine worm nitrile in application facet, has the farming of reduction originally, improves the advantage of preventive effect; Compare with Mobucin, have the expansion insecticidal spectrum, strengthen the advantage of lasting effect.In addition,, therefore, totally reduced the effective dose of medicament, improved the medicament service efficiency because the present invention has the synergy effect.
7, the present invention is environment-friendly type, high-performance insecticidal preparation, along with country will more meet industrial policy to the forbidding of the malicious organic phosphor of height, more meets the agricultural production needs.
Embodiment
Below in conjunction with embodiment the present invention is further described:
In the following embodiments, Pesticidal combination of the present invention is further described, but its active ingredient and proportioning thereof, auxiliary composition and addition thereof etc. all are not limited to following examples.In addition, all umber is all by weight among the embodiment.
Embodiment about preparation
The preparation processing mode is carried out routinely, and its composition and parts by weight are as follows:
Example of formulations 1:78% water dispersible granules
| The composition title | Umber |
| Fluorine worm nitrile | 3 parts |
| Mobucin | 75 parts |
| Wetting agent (fatty alcohol ether 2+ alkyl sulfate 2) | 4 parts |
| Composite dispersing agent | 6 parts |
| Mineral salt | Supply 100 parts |
| Example of formulations 2:35% suspending agent | |
| The composition title | Umber |
| Fluorine worm nitrile | 5 parts |
| Mobucin | 30 parts |
| Ethylene glycol | 10 parts |
| Neopelex | 5 parts |
| Xanthans | 1 part |
| Stabilizing agent | 4 parts |
| Water | Supply 100 parts |
| Example of formulations 3:50% aqueous emulsion | |
| The composition title | Umber |
| Fluorine worm nitrile | 1 part |
| Mobucin | 49 parts |
| Solvent | 5 parts |
| Emulsifier | 15 parts |
| Defoamer | 1 part |
| Water | Supply 100 parts |
| Example of formulations 4:22% wetting powder | |
| The composition title | Umber |
| Fluorine worm nitrile | 2 parts |
| Mobucin | 20 parts |
| Stabilizing agent | 8 parts |
| Sldium lauryl sulfate | 10 parts |
| Lignosite | 10 parts |
| Kaolin | 50 parts |
| Example of formulations 5:10% missible oil | |
| The composition title | Umber |
| Fluorine worm nitrile | 5 parts |
| Mobucin | 5 parts |
| Tween 80 | 12 parts |
| N, dinethylformamide | 5 parts |
| Dimethylbenzene | Supply 100 parts |
Enumerating concrete experimental example has the composition of insecticidal activity to the present invention application and feasibility below describes.
Embodiment about test
Experimental example 1: the medicament screening of snout moth's larva class pests such as control striped rice borer
Test objective: the snout moth's larva class pest comprises striped rice borer, paddy stem borer, rice leaf roller, pink rice borer etc., the present invention adopts the striped rice borer of laboratory artificial feeding, screening fluorine worm nitriles etc. are to the indoor virulence of striped rice borer, estimate the status of fluorine worm nitrile in control snout moth's larva class medicament, for the research and development of fluorine worm nitrile provide foundation.
Method: soak the rice seedling feeding method.Operating procedure is as follows:
Rice seedling is cultivated and chosen: adopt the rice seedling of raising striped rice borer, height is about 100mm.The soup preparation: dilute behind the former medicinal acetone solution, the Tween 80 aqueous solution with 0.05% is diluted to soup, and preparation directly dilutes with running water.Chemicals treatment: rice seedling is flooded 10s in soup, take out and place on the blotting paper disposable the moulding in the cup of packing into after drying naturally.Connect worm: every treatment dosage connects 30 of worms.To there be the medicine rice seedling to pack in the cup, insert larva, 10 every glass, repeat 3 times.Breeding observing and inspection as a result: preserve moisture and illumination cultivation, check borer population anyway in the time of the 5th day, calculate LC
50
Result and analysis:
Medicaments such as table 2 fluorine worm nitrile are to the Toxicity Determination of striped rice borer
| Reagent agent | Y＝a+bx | Virulence LC 50(mgL -1) 95% fiducial limit | Relative virus force index |
| Fluorine worm nitrile | Y＝9.8527+2.7969x | 0.0184(0.0148～0.0229) | 351000.09 |
| First dimension salt | Y＝7.5316+1.2262x | 0.0194(0.014 3～0.0264) | 332915.98 |
| Furans worm hydrazides | Y＝3.5481+1.2269x | 38.4914(30.9160～47.9224) | 167.79 |
| Hostathion | Y＝1.2343+2.0803x | 64.5857(51.3928～81.1653) | 100 |
From the analysis of table 2 relative virus force index, fluorine worm nitrile is effectively, is the contrast medicament with the Hostathion, and the relative virus force index of fluorine worm nitrile is 351000.09, exceeds 4 orders of magnitude than Hostathion, belongs to the super-high-efficient medicament.
Experimental example 2: the composition of fluorine-containing worm nitrile and Mobucin is to the indoor screening active ingredients of brown planthopper
Test objective: the plant hopper insect comprises brown planthopper, small brown rice planthopper, white-backed planthopper etc., the present invention adopts the brown planthopper of laboratory artificial feeding, the synergy characteristics of research fluorine worm nitrile and Mobucin, the compound synergic of screening fluorine worm nitrile and Mobucin makes up, for the research and development of fluorine worm nitrile and Mobucin complex preparation provide foundation.
Method: rice seedling infusion process.Operating procedure is as follows:
Rice seedling is cultivated and chosen: adopt (hybrid rice) rice seedling of raising brown planthopper, height is about 100mm.The soup preparation: dilute behind the former medicinal acetone solution, the Tween 80 aqueous solution with 0.05% is diluted to soup, and preparation directly dilutes with running water.Chemicals treatment: rice seedling is flooded 10s in soup, take out and place on the blotting paper disposable the moulding in the cup of packing into after drying naturally.Connect worm: every treatment dosage connects 45 of worms (nymph/adult).To there be the medicine rice seedling to pack in the cup, insert the examination worm, 15 every glass, repeat 3 times.Breeding observing and inspection as a result: preserve moisture and illumination cultivation, check borer population anyway in the time of the 3rd day, calculate LC
50
Synergistic effect=actual-theoretical lethality, synergistic effect value are greater than 5, and expression has synergy trend, and between-5～5, expression has summation action, and less than-5, expression has antagonism.
Theoretical lethality P
A+B=1-(1-P
A) (1-P
B)
Co-toxicity coefficient adopts the abundant method of Sun Yun to calculate.The toxicity index that co-toxicity coefficient CTC=100 * actual toxicity index/theory of using with is used with.When co-toxicity coefficient obviously greater than 120, showing has synergistic effect, big must be many more, synergy is remarkable more; When co-toxicity coefficient is 80～120, represent to have summation action; When co-toxicity coefficient less than 80, showing has antagonism.
Result and analysis:
To 3 age nymph test result such as table 3.With the Imidacloprid is the contrast medicament, and the relative virus force index of fluorine worm nitrile, Mobucin is respectively 125.50,1.98.
Fluorine worm nitrile and Mobucin compounded combination are to test result such as the table 4 of nymph.
Table 3 fluorine worm nitrile, Mobucin are to the toxicity test result of brown planthopper nymph
| Reagent agent | The worm attitude | Y＝a+bx | Virulence LC 50(mgL -1) 95% fiducial limit | Relative virus force index |
| Fluorine worm nitrile | Nymph | Y＝5.3684+2.8309x | 0.7418(0.5884～0.9351) | 125.50 |
| Mobucin | Nymph | Y＝2.1879+1.6812x | 47.0549(35.1067～63.0696) | 1.98 |
| Imidacloprid | Nymph | Y＝5.0329+1.0433x | 0.9300(0.6595～1.3114) | 100 |
Table 4 fluorine worm nitrile and Mobucin synergy test result
| Reagent agent | First group of proof load (mgL -1) | First group of synergistic effect | Second group of proof load (mgL -1) | Second group of synergistic effect |
| Fluorine worm nitrile+Mobucin 100+1 | 1+0.01 | 0.50 | 0.5+0.005 | 1.50 |
| Fluorine worm nitrile+Mobucin 40+1 | 1+0.025 | 4.00 | 0.5+0.0125 | 3.50 |
| Fluorine worm nitrile+Mobucin 10+1 | 1+0.1 | 5.50 | 0.5+0.05 | 5.00 |
| Fluorine worm nitrile+Mobucin 4+1 | 1+0.25 | 6.00 | 0.5+0.125 | 7.50 |
| Fluorine worm nitrile+Mobucin 1+1 | 1+1 | 8.50 | 0.5+0.5 | 8.50 |
| Fluorine worm nitrile+Mobucin 1+4 | 1+4 | 22.00 | 0.5+2 | 19.00 |
| Fluorine worm nitrile+Mobucin 1+10 | 1+10 | 18.33 | 0.5+5 | 16.67 |
| Fluorine worm nitrile+Mobucin 1+40 | 1+40 | 15.18 | 0.5+20 | 13.33 |
| Fluorine worm nitrile+Mobucin 1+100 | 1+100 | 5.40 | 0.5+50 | 6.00 |
As can be seen from Table 4, the synergy general trend of two groups of proof loads is consistent, all presents addition or synergy.When proportioning synergy trend in this scope of 10+1 to 1+40 obvious.
Experimental example 3: the synergy ratio optimization screening of fluorine worm nitrile and Mobucin
Can analyze from experimental example 2, fluorine worm nitrile and Mobucin have remarkable synergy trend in 1: 0.1～40 scopes, therefore, design relative ratio range and carried out ratio optimization, filter out the stronger combination of practicality, method is with experimental example 2, result such as table 5.Co-toxicity coefficient is 125.00～337.14.In fact, when the weight proportion of fluorine worm nitrile and Mobucin in the composition was 1: 1～75, synergistic effect was all remarkable.According to this indoor measurement result, compare with conventional dose or single agent, when control plant hopper insect, be very effective.
Table 5 fluorine worm nitrile and Mobucin ratio optimization filler test
| Reagent agent | Virulence LC 50(mgL -1) | Co-toxicity coefficient CTC |
| Fluorine worm nitrile+Mobucin 1+1 | 0.9258 | 157.76 |
| Fluorine worm nitrile+Mobucin 1+2 | 1.1647 | 185.23 |
| Fluorine worm nitrile+Mobucin 1+4 | 1.0349 | 337.14 |
| Fluorine worm nitrile+Mobucin 1+10 | 2.6106 | 270.00 |
| Fluorine worm nitrile+Mobucin 1+15 | 4.3604 | 220.14 |
| Fluorine worm nitrile+Mobucin 1+20 | 6.1749 | 191.81 |
| Fluorine worm nitrile+Mobucin 1+40 | 12.4672 | 149.61 |
| Fluorine worm nitrile+Mobucin 1+50 | 15.0573 | 140.50 |
| Fluorine worm nitrile+Mobucin 1+75 | 20.6670 | 125.00 |
| Fluorine worm nitrile | 0.7418 | |
| Mobucin | 47.0549 |
The foregoing description only is explanation technical conceive of the present invention and characteristics, and its purpose is to allow the personage who is familiar with this technology can understand content of the present invention and enforcement according to this, can not limit protection scope of the present invention with this.All equivalences that spirit essence is done according to the present invention change or modify, and all should be encompassed within protection scope of the present invention.
Claims (3)
1, the Pesticidal combination of a kind of fluorine-containing worm nitrile and Mobucin, it is characterized in that: effective active components comprises:
A component: 5-amino-1-(2,6-dichlor-4-trifluoromethyl phenyl)-4-trifluoromethyl sulfinyl pyrazole-3-nitrile;
B component: o-isopropyl phenyl methyl carbamate;
The weight proportion of A component and B component is 1: 0.1～75.
2, Pesticidal combination according to claim 1 is characterized in that: the weight proportion of described A component and B component is 1: 1～75.
3, Pesticidal combination according to claim 1 and 2 is characterized in that: described composition is water dispersible granules or formulations such as suspending agent or aqueous emulsion or wetting powder or missible oil.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007100195739A CN100433979C (en) | 2007-01-18 | 2007-01-18 | Compound insecticide containing fipronil and Etrofolan |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007100195739A CN100433979C (en) | 2007-01-18 | 2007-01-18 | Compound insecticide containing fipronil and Etrofolan |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN100998330A true CN100998330A (en) | 2007-07-18 |
| CN100433979C CN100433979C (en) | 2008-11-19 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2007100195739A Expired - Fee Related CN100433979C (en) | 2007-01-18 | 2007-01-18 | Compound insecticide containing fipronil and Etrofolan |
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| Country | Link |
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| CN (1) | CN100433979C (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104855402A (en) * | 2015-05-15 | 2015-08-26 | 江苏徐淮地区淮阴农业科学研究所 | Butene-fipronil and isoprocarb combined pesticide |
| CN105941437A (en) * | 2016-06-24 | 2016-09-21 | 江苏省绿盾植保农药实验有限公司 | Compound insecticide containing afidopyropen and fipronil and application thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1187300A (en) * | 1997-01-09 | 1998-07-15 | 湖南省东永农药厂 | Pesticide imidacloprid composition series |
| FR2798822B1 (en) * | 1999-09-28 | 2006-08-04 | Aventis Cropscience Sa | CARBAMATE-ASSOCIATED INSECTICIDE COMPOSITIONS WITH PYRAZOLE, PYRROLE OR PHENYLIMIDAZOLE GROUP INSECTICIDE |
| CN1129358C (en) * | 1999-12-15 | 2003-12-03 | 江苏省新沂中凯农用化工有限公司 | Pesticide composition containing fipronil |
| CN1903029A (en) * | 2005-07-27 | 2007-01-31 | 拜尔农作物科学有限公司 | Microemulsion |
| CN1317951C (en) * | 2005-08-19 | 2007-05-30 | 张光来 | Fipronil and fenobucarb composite pesticide |
-
2007
- 2007-01-18 CN CNB2007100195739A patent/CN100433979C/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104855402A (en) * | 2015-05-15 | 2015-08-26 | 江苏徐淮地区淮阴农业科学研究所 | Butene-fipronil and isoprocarb combined pesticide |
| CN105941437A (en) * | 2016-06-24 | 2016-09-21 | 江苏省绿盾植保农药实验有限公司 | Compound insecticide containing afidopyropen and fipronil and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100433979C (en) | 2008-11-19 |
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