CN100546577C - 水飞蓟宾或其盐的医药新用途 - Google Patents
水飞蓟宾或其盐的医药新用途 Download PDFInfo
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- CN100546577C CN100546577C CNB2004100363764A CN200410036376A CN100546577C CN 100546577 C CN100546577 C CN 100546577C CN B2004100363764 A CNB2004100363764 A CN B2004100363764A CN 200410036376 A CN200410036376 A CN 200410036376A CN 100546577 C CN100546577 C CN 100546577C
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- silibinin
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- endotoxin
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Application Number | Priority Date | Filing Date | Title |
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CNB2004100363764A CN100546577C (zh) | 2004-11-22 | 2004-11-22 | 水飞蓟宾或其盐的医药新用途 |
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CNB2004100363764A CN100546577C (zh) | 2004-11-22 | 2004-11-22 | 水飞蓟宾或其盐的医药新用途 |
Publications (2)
Publication Number | Publication Date |
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CN1778295A CN1778295A (zh) | 2006-05-31 |
CN100546577C true CN100546577C (zh) | 2009-10-07 |
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CNB2004100363764A Expired - Fee Related CN100546577C (zh) | 2004-11-22 | 2004-11-22 | 水飞蓟宾或其盐的医药新用途 |
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CN (1) | CN100546577C (zh) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ2008407A3 (cs) * | 2008-06-26 | 2009-08-26 | Agra Group, A. S. | Vodorozpustný prípravek na bázi flavanonol lignanu a zpusob jeho prípravy |
WO2011104667A1 (en) * | 2010-02-25 | 2011-09-01 | Anthem Biosciences Private Limited | Basic aminoacid salts of polyphenols |
CN102805866B (zh) * | 2012-08-23 | 2015-04-08 | 河南新正好生物工程有限公司 | 一种兽用药物制剂及其应用 |
CN114617872A (zh) * | 2022-03-04 | 2022-06-14 | 西北大学 | Sil用于制备抗败血症及其诱发的心肌损伤药物的应用 |
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2004
- 2004-11-22 CN CNB2004100363764A patent/CN100546577C/zh not_active Expired - Fee Related
Non-Patent Citations (7)
Title |
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Inhibition of inducible nitric oxide synthase andcyclooxygenase-2 expression by flavonoids in macrophageJ774A.1. Giuseppina Mattace Raso, et al.Life Sciences,Vol.68 . 2001 |
Inhibition of inducible nitric oxide synthase andcyclooxygenase-2 expression by flavonoids in macrophageJ774A.1. Giuseppina Mattace Raso, et al.Life Sciences,Vol.68. 2001 * |
Protection against lipopolysaccharide-induced sepsis andinhibition of interleukin-1β and prostaglandin E2 synthesis bysilymarin. Jong Soon Kang, et al.Biochemical Pharmacology,Vol.67 No.1. 2004 |
Protection against lipopolysaccharide-induced sepsis andinhibition of interleukin-1β and prostaglandin E2 synthesis bysilymarin. Jong Soon Kang, et al.Biochemical Pharmacology,Vol.67 No.1. 2004 * |
Selective inhibition of NF-kB activation by the flavonoidhepatoprotector silymarin in HepG2 Evidence for differentactivating pathways. Claude Saliou, et al.FEBS Letters,Vol.440 No.1. 1998 |
Selective inhibition of NF-kB activation by the flavonoidhepatoprotector silymarin in HepG2 Evidence for differentactivating pathways. Claude Saliou, et al.FEBS Letters,Vol.440 No.1. 1998 * |
水飞蓟宾对小鼠肝脏炎症损伤和肿瘤坏死因子的产生及活性的影响. 张俊平等.药学学报,第31卷第8期. 1996 |
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Publication number | Publication date |
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CN1778295A (zh) | 2006-05-31 |
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Effective date of registration: 20170608 Address after: 264670, No. 15, pioneering Road, hi tech Zone, Shandong, Yantai Patentee after: SHANDONG LUYE PHARMACEUTICAL Co.,Ltd. Address before: 264003 Laishan, Shandong Province Bao Road, No. 9 District, No. Patentee before: SHANDONG LUYE NATURAL DRUG RESEARCH AND DEVELOPMENT CO.,LTD. |
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Effective date of registration: 20191016 Address after: 264005, Qingquan Road, Laishan District, Shandong, Yantai, 30 Patentee after: Yantai University Address before: 264670, No. 15, pioneering Road, hi tech Zone, Shandong, Yantai Patentee before: SHANDONG LUYE PHARMACEUTICAL Co.,Ltd. |
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CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20091007 |