CN100534457C - Chinese traditional medicine compound took orally for treating ankylosing spondylitis - Google Patents

Chinese traditional medicine compound took orally for treating ankylosing spondylitis Download PDF

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CN100534457C
CN100534457C CNB2007100154052A CN200710015405A CN100534457C CN 100534457 C CN100534457 C CN 100534457C CN B2007100154052 A CNB2007100154052 A CN B2007100154052A CN 200710015405 A CN200710015405 A CN 200710015405A CN 100534457 C CN100534457 C CN 100534457C
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ankylosing spondylitis
caulis
radix
took orally
treating ankylosing
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CNB2007100154052A
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CN101040908A (en
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徐恒雁
魏芸
戴振林
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Abstract

The invention disclesos an oral Chinese drug composite for treating rachitis, belonging to Chinese drug technique, formed by spatholobus stem, orientavine, Tripterygium wilfordii, barren wort, woodwardic, phrymaro, anoelica sinensis, or the like, which should be boiled and taken. The invention combines aforementioned drugs to obtain cooperation function, which can adjust immunity or the like, with significant treatment effect on rachitis.

Description

A kind of Chinese medicine composition of took orally for treating ankylosing spondylitis
Technical field
The present invention relates to a kind of Chinese medicine composition of took orally for treating ankylosing spondylitis, belong to the field of Chinese medicines.
Background technology
Ankylosing spondylitis is a kind of chronic, carrying out property, the arthropathy of axis joint involvement, and organize on the sacroiliac joint, joint of vertebral column and the vertebra side that mainly influence pelvis.Main morbidity is at the young man in 20-30 year, and morbidity is rare more than 40 years old.The women is ill to be male 1/10th only, and the state of an illness is lighter.
The pathogenic factor of ankylosing spondylitis is unclear, but with inherited genetic factors confidential relation is arranged.In the patients with ankylosing spondylitis, in the gene and only there be about 5% among the general population up to 90% the HLA-B27 positive rate.The infection of some specific part may be relevant with morbidity as prostatitis, ulcerative colitis.This sick onset is concealment, makes slow progress.Early symptom is waist stiff sense or stiff pain often, stands up at night, get up, or sitting, back, station symptom is particularly evident for a long time, and through after the activity, stiff pain can take a turn for the better.Except that the lumbosacral region joint is subjected to the class, disease can be involved thoracic vertebra and cervical vertebra, shows as stiff and pain in various degree.Big joint around the part, as: shoulder joint, knee joint, hip joint, minority involve foot, the little joint of hands, but arthritis mostly is few joint on every side, asymmetric morbidity.Except that the symptom of joint, can be with low grade fever, weak, loss of appetite, become thin, symptom such as anemia.Part patient lower limb position muscular soreness and numbness below knee occur because of lower limb peripheral nerve pathological changes.About 1/4th patients have the iris cyclitis, ophthalmalgia, photophobia occur and shed tears.More serious patient is with heart aortic valve disease and pulmonary fibrosis.Along with the development of the state of an illness, patient's lumbar vertebra, thoracic vertebra, cervical spondylosis can increase the weight of gradually, and it is anteflexion that cervical vertebra appears in part patient, and thoracic vertebra is straight, hip joint flexing deformity, thereby have a strong impact on patient's mobility.Lab testing can find that immunoglobulin and erythrocyte sedimentation rate obviously increase.The HLA-B27 site positive prompts for the high-risk group.The X line is taken the photograph the sheet inspection and is had diagnostic value, and the patient has distinctive sacroiliac joint to change and spinal column " ring sample " changes.
Medication medication such as the anti-inflammatory analgesic of conventional therapy ankylosing spondylitis, immune formulation, hormone are a lot of at present, but can not fundamentally treat mostly, and some side effect is arranged, and stomach, liver, kidney are also had very big infringement.
Summary of the invention
The present invention overcomes the Chinese medicine composition that has the deficiency for the treatment of now and a kind of took orally for treating ankylosing spondylitis is provided, and all selects natural Chinese medicinal herb for use, can effectively treat ankylosing spondylitis.
Technical scheme of the present invention is: the Chinese medicine composition of this kind took orally for treating ankylosing spondylitis, it is characterized in that, make the raw materials of effective components medicine and be: Caulis Spatholobi 9~30, Caulis Sinomenii 9~15, Radix Tripterygii Wilfordii 8~12, Herba Epimedii 6~12, Rhizoma Cibotii 6~12, Herba Lycopodii (Caulis Tinosporae) 5~10, Herba speranskiae tuberculatae 6~10, Radix Angelicae Sinensis 10~20, Radix Paeoniae Alba (parched) 6~12, Carapax Trionycis (processed) 5~10, Pheretima 5~10, Squama Manis 6~12 and Eupolyphaga Seu Steleophaga 5~10 by following weight portion.
Be decocted in water for oral dose 1 dose of every day, divide clothes 2 times.15 days is a course of treatment.
Further technical scheme of the present invention is: the Chinese medicine composition of this kind took orally for treating ankylosing spondylitis, it is characterized in that, make the raw materials of effective components medicine and be: Caulis Spatholobi 20, Caulis Sinomenii 12, Radix Tripterygii Wilfordii 10, Herba Epimedii 10, Rhizoma Cibotii 10, Herba Lycopodii (Caulis Tinosporae) 8, Herba speranskiae tuberculatae 8, Radix Angelicae Sinensis 15, Radix Paeoniae Alba (parched) 10, Carapax Trionycis (processed) 8, Pheretima 8, Squama Manis 8 and Eupolyphaga Seu Steleophaga 8 by following weight portion.
Be decocted in water for oral dose 1 dose of every day, divide clothes 2 times.15 days is a course of treatment.
Pharmacological action:
Caulis Spatholobi: bitter, sweet, temperature.Return liver, kidney channel.Function cures mainly: enrich blood, invigorate blood circulation, collateral dredging.Be used for menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.
Caulis Sinomenii: bitter, suffering is returned liver, spleen channel, wind-damp dispelling, the meridian dredging, diuresis.Be used for rheumatic arthralgia, arthroncus, paralysis pruritus.
Radix Tripterygii Wilfordii: bitter, hot, cold.Big poison.Return liver, spleen, lung meridian.Anticancer, damp eliminating eliminating stagnation relieves internal heat.
Herba Epimedii: kidney invigorating and YANG supporting, expelling wind and removing dampness.Control the sexual impotence erectile problem, dribbling urination, the muscles and bones contraction is anxious, hemiplegia, weakness of the waist and knees, rheumatism carbuncle pain, extremity are meciless.
Rhizoma Cibotii: bitter, sweet, temperature.Return liver, kidney channel.Invigorating the liver and kidney, strong spinal column, wind-damp dispelling.Be used for soreness of the waist and knees, weakness of the lower extremities, rheumatic arthralgia.
Herba Lycopodii (Caulis Tinosporae): little hardship, cold.Relaxing muscles and tendons and activating QI and blood in the collateral, wind-expelling pain-stopping.Be used for rheumatic arthralgia, sciatica, lumbar muscle strain, traumatic injury.
Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Radix Paeoniae Alba (parched): nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.
Carapax Trionycis (processed): salty, be slightly cold.Return liver, kidney channel.Nourishing YIN for suppressing the hyperactive YANG, hard masses softening and resolving is brought down a fever to remove and is steamed.Be used for fever due to yin deficiency, consumptive fever hectic fever due to YIN-deficiency, stirring-up of pathogenic wind in the interior resulting from deficiency, amenorrhea , mass in the abdomen, chronic malaria malaria with splenomegaly.
Herba speranskiae tuberculatae: hot, bitter, temperature.Slightly poisonous.Return liver, kidney channel.Expelling wind and removing dampness, the detoxifcation pain relieving.Be used for rheumatic arthritis;
Pheretima: salty-cold.Heat clearing away, spasmolytic, diuresis, detoxifcation.Control calentura mania and irritation, infantile convulsion, cough with asthma, headache conjunctival congestion, laryngopharynx swelling and pain, urinary obstruction, Fengshi Guanjie pain, diseases such as hemiplegia.
Squama Manis: it is swollen to control the carbuncle skin ulcer, anemofrigid-damp arthralgia, and amenorrhea, galactostasis is had blood in stool.
Eupolyphaga Seu Steleophaga: cold in nature, little poison is arranged.Having silt hemostasis, reducing swelling and alleviating pain, the collateral dredging reason is hindered, and connects effects such as muscle symplectic bone.
The present invention is with after the said medicine combination, and its drug effect has synergism, and the Chinese medicine composition of this kind took orally for treating ankylosing spondylitis can kidney tonifying, arthralgia aggravated by cold is superintended and directed, invigorated blood circulation to temperature, detoxifcation, chemical fibre, adjusting autoimmune mechanism.Through a large amount of clinical observations, the good curing effect is arranged at the ankylosing spondylitis lesions position.
Model case:
Example one: Feng, the woman 29 years old, suffers from ankylosing spondylitis surplus hunchback in 3 years, the rigid back pain, stiff, limitation of activity, the two lower limb disorders of companion, once treatment ined all sorts of ways over 5 years, the state of an illness not only not slowly, increases the weight of on the contrary gradually, and is agonizing, through the traditional Chinese medicine composition for treating of this kind took orally for treating ankylosing spondylitis after January, symptom is obviously improved, and treats after three months, and symptom disappears substantially, after again after after treatment half a year, but back stretches and left-right rotation, and curved stretching freely followed up a case by regular visits to so far and do not seen repeatedly.
Example two: Cao, the man 37 years old, suffered from tetanic spondylitis 6 years.When the patient just fell ill, with right arthroncus of knee joints pain, companion's lumbago was persistence.X-ray sheet demonstration on 2003 days: two sacroiliac joint faces are crude.Gap turn narrow is irregular, and the right side is heavy, right knee joint-effusion, and synovial membrane thickens, and is not good enough through how tame hospitalize.In the Chinese medicine composition of this kind of clothes took orally for treating ankylosing spondylitis in 2004, the disappearance of swelling and ache, functional rehabilitation.In December, 2005 X-ray examination: articular surface is crude, and the worm-eaten sample changes.Existing arthralgia disappears, life, working properly.
Example three: high certain, man 33 years old suffered from ankylosing spondylitis more than 10 year, lumbago and backache is accompanied left hip joint twinge, left hip joint early-fixed, no movable function, the joint space narrows down, because of the patient is afraid of to operate on, the expense height, damage is big, is illustrated in through the ward mate, by the traditional Chinese medicine composition for treating of oral this kind took orally for treating ankylosing spondylitis, after three months, left side hip joint can flexible motion, pain relief, after again after after treatment three courses of treatment, painful complete obiteration, the back activity freely, the motion of left hip joint has discomfort freely slightly after the work, die away after the rest, follow up a case by regular visits to so far and do not see repeatedly.
Example four: Tang, the man, 17 years old, the stiff pain of waist sacrum and right hip 4 years can not be walked and squat down, and suspends schooling more than 2 years.Check to find to refer to 32 centimetres of distances, " 4 " word left sides (+), right (++ ++) singly turned 20 meters of walkings 42 seconds, right hip is tetanic at 150 degree, function total loss.AS merges the right lateral thigh head necrosis III phase.Pelycogram: (97.10.13) two sacroiliac jointes merge, only 0.5 millimeter of right hip narrow gaps, and acetabular bone and femoral head have big folliculus destruction, and bone trabecula is seriously sparse.After the traditional Chinese medicine composition for treating of this kind took orally for treating ankylosing spondylitis, refer to 0 centimetre of distance, went to turn 20 meters of walkings 14 seconds, walk, jump, run, squat down, go up all normal downstairs.The check pelycogram: (98.10.14) right hip gap is widened 3 millimeters, the whole complete obiterations of the original capsule destruction of right limbus of acetabulum and right femoral head, and the area of new bone girder is arranged in order, and bone density increases normal.
The specific embodiment
Example one: a kind of Chinese medicine composition of took orally for treating ankylosing spondylitis, make the raw materials of effective components medicine and be: Caulis Spatholobi 9, Caulis Sinomenii 9, Radix Tripterygii Wilfordii 8, Herba Epimedii 6, Rhizoma Cibotii 6, Herba Lycopodii (Caulis Tinosporae) 5, Herba speranskiae tuberculatae 6, Radix Angelicae Sinensis 10, Radix Paeoniae Alba (parched) 6, Carapax Trionycis (processed) 5, Pheretima 5, Squama Manis 6 and Eupolyphaga Seu Steleophaga 5 by following weight portion.
Be decocted in water for oral dose 1 dose of every day, divide clothes 2 times.15 days is a course of treatment.
Example two: a kind of Chinese medicine composition of took orally for treating ankylosing spondylitis, make the raw materials of effective components medicine and be: Caulis Spatholobi 30, Caulis Sinomenii 15, Radix Tripterygii Wilfordii 12, Herba Epimedii 12, Rhizoma Cibotii 12, Herba Lycopodii (Caulis Tinosporae) 10, Herba speranskiae tuberculatae 10, Radix Angelicae Sinensis 20, Radix Paeoniae Alba (parched) 12, Carapax Trionycis (processed) 10, Pheretima 10, Squama Manis 12 and Eupolyphaga Seu Steleophaga 10 by following weight portion.
Be decocted in water for oral dose 1 dose of every day, divide clothes 2 times.15 days is a course of treatment.
Example three: a kind of Chinese medicine composition of took orally for treating ankylosing spondylitis, make the raw materials of effective components medicine and be: Caulis Spatholobi 15, Caulis Sinomenii 12, Radix Tripterygii Wilfordii 9, Herba Epimedii 10, Rhizoma Cibotii 8, Herba Lycopodii (Caulis Tinosporae) 7, Herba speranskiae tuberculatae 9, Radix Angelicae Sinensis 16, Radix Paeoniae Alba (parched) 11, Carapax Trionycis (processed) 6, Pheretima 8, Squama Manis 7 and Eupolyphaga Seu Steleophaga 6 by following weight portion.
Be decocted in water for oral dose 1 dose of every day, divide clothes 2 times.15 days is a course of treatment.
Example four: a kind of Chinese medicine composition of took orally for treating ankylosing spondylitis, make the raw materials of effective components medicine and be: Caulis Spatholobi 20, Caulis Sinomenii 12, Radix Tripterygii Wilfordii 10, Herba Epimedii 10, Rhizoma Cibotii 10, Herba Lycopodii (Caulis Tinosporae) 8, Herba speranskiae tuberculatae 8, Radix Angelicae Sinensis 15, Radix Paeoniae Alba (parched) 10, Carapax Trionycis (processed) 8, Pheretima 8, Squama Manis 8 and Eupolyphaga Seu Steleophaga 8 by following weight portion.
Be decocted in water for oral dose 1 dose of every day, divide clothes 2 times.15 days is a course of treatment.

Claims (2)

1, a kind of Chinese medicine composition of took orally for treating ankylosing spondylitis, it is characterized in that, make the raw materials of effective components medicine and be: Caulis Spatholobi 9~30, Caulis Sinomenii 9~15, Radix Tripterygii Wilfordii 8~12, Herba Epimedii 6~12, Rhizoma Cibotii 6~12, Caulis Tinosporae 5~10, Herba speranskiae tuberculatae 6~10, Radix Angelicae Sinensis 10~20, Radix Paeoniae Alba (parched) 6~12, Carapax Trionycis (processed) 5~10, Pheretima 5~10, Squama Manis 6~12 and Eupolyphaga Seu Steleophaga 5~10 by following weight portion.
2, according to the Chinese medicine composition of claim 1 described a kind of took orally for treating ankylosing spondylitis, it is characterized in that, make the raw materials of effective components medicine and be: Caulis Spatholobi 20, Caulis Sinomenii 12, Radix Tripterygii Wilfordii 10, Herba Epimedii 10, Rhizoma Cibotii 10, Caulis Tinosporae 8, Herba speranskiae tuberculatae 8, Radix Angelicae Sinensis 15, Radix Paeoniae Alba (parched) 10, Carapax Trionycis (processed) 8, Pheretima 8, Squama Manis 8 and Eupolyphaga Seu Steleophaga 8 by following weight portion.
CNB2007100154052A 2007-04-20 2007-04-20 Chinese traditional medicine compound took orally for treating ankylosing spondylitis Expired - Fee Related CN100534457C (en)

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102091137B (en) * 2011-01-09 2012-07-04 王殿玲 Chinese herbal preparation for treating ankylosing spondylitis
CN102784328B (en) * 2012-08-26 2014-06-04 孙超 Medicament for treating ankylosing spondylitis and preparation method of medicament

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
强直通痹汤治疗强直性脊柱炎30例. 陈忠跃,周恩庆.陕西中医,第26卷第4期. 2005
强直通痹汤治疗强直性脊柱炎30例. 陈忠跃,周恩庆.陕西中医,第26卷第4期. 2005 *

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