CN105106406A - Traditional Chinese medicine composition for treating lumbar disc herniation and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating lumbar disc herniation and preparation method thereof Download PDF

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CN105106406A
CN105106406A CN201510587035.4A CN201510587035A CN105106406A CN 105106406 A CN105106406 A CN 105106406A CN 201510587035 A CN201510587035 A CN 201510587035A CN 105106406 A CN105106406 A CN 105106406A
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radix
chinese medicine
medicine composition
prolapse
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CN105106406B (en
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吴金洲
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Hunan Tianhua Medical Biological Technology Co.,Ltd.
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Abstract

The invention relates to a traditional Chinese medicine composition for treating lumbar disc herniation and a preparation method thereof and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition for treating the lumbar disc herniation is prepared from, by weight, 50-70 parts of angelica sinensis, 40-50 parts of white paeony roots, 55-65 parts of prepared rhizomes of rehmannia, 35-45 parts of roots of bidentate achyranthes, 45-55 parts of eucommia barks, 35-45 parts of radix astragali, 25-35 parts of roots of red-rooted salvia, 25-35 parts of desertliving cistanche, 20-30 parts of radix morindae officinalis and 25-35 parts of pseudo-ginsengs. The traditional Chinese medicine composition is convenient to take, can rapidly improve local blood circulation and clear and activate the channels and collaterals, can effectively treat the lumbar disc herniation and hyperostosis, eliminates the pain of patients and enables the patients to move freely, and the efficacy of the composition can be directly played at the focus position.

Description

A kind of Chinese medicine composition for the treatment of prolapse of lumbar intervertebral disc and preparation method thereof
Technical field
The invention belongs to technical field of Chinese medicine, be specifically related to a kind of Chinese medicine composition for the treatment of prolapse of lumbar intervertebral disc and preparation method thereof.
Background technology
Prolapse of lumbar intervertebral disc (1umbarnterevrtehradischerniation, LIDH) also known as " Annulus Fibrosus of Lumbar Intervertebral Discs break disease ", refer to Nucleus pulposus after Anular disruption, to stimulate and compressing lumbar root or cauda equina nerve cause lumbago and skelalgia, the numb clinical common disease of one.
Prolapse of lumbar intervertebral disc belongs to the category of Chinese medicine " arthromyodynia ", " lumbago ", " lumbago and skelalgia ", Ancient Times in China to have relevant understanding very early.As " the perverse lumbago section of Plain Questions ": " belt vessel makes us lumbago, cannot pitching, faces upward and then probably falls forward, weight lifting hinder waist.Weighing apparatus network is exhausted, and stagnant blood returns it "; " yangpu point makes us lumbago, cannot cough, and coughs then Jinsuo anxious ", has explicitly pointed out the related symptoms of lumbago.Prolapse of lumbar intervertebral disc is common clinical, high morbidity, and age of onset section is distributed more widely, and men and women, old and young all have a patient, are many with the middle aged body person of tiring out.
The pathogeny of prolapse of lumbar intervertebral disc is: the undue force of human body, overload, intercalated disc Anular disruption and Nucleus pulposus, or asthenia of suffering from a deficiency of the kidney after person in middle and old age, intercalated disc elasticity reduces degenerates and bulging, the portion extrusion spinal cord dural sac of described outstanding or bulging or nerve root, produce abnormal stimulation, make blood flow occur obstacle, cause tissue ischemia anoxia, metabolism alluvial swelling and falling ill.This disease can cause human body ailing, and numb, aching and tired, the symptoms such as walking disorder, even there will be crural paralysis, the serious consequences such as incontinence of urination and defecation.A lot of patient due to treatment not in time, thorough, cause paralysis bed, disability.
After this disease is named in the last hundred years, domestic and international medical circle is carrying out constantly exploration always, find and develop method and the medicine that can cure this disease, the Main Means that current treatment prolapse of lumbar intervertebral disc adopts is: draw and make anesthesia needle, these methods can only alleviate or respite ailing, can not efficient solution except the wind-cold damp pathogen of local and the swelling in affected part and pain due to blood stasis, pain relieving, analgesic effect are undesirable, patient suffering is large and the course for the treatment of is long, and easily recurs.Can also adopt the method for operation for the patient that said method is invalid, though operation instant effect has a big risk, the misery of patient is comparatively large, and costly, and sequela is more in operation.Therefore in sum, at present for prolapse of lumbar intervertebral disc, more preferably Therapeutic Method to be developed is had.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art and provide a kind of Chinese medicine composition for the treatment of prolapse of lumbar intervertebral disc and preparation method thereof, this medicine can effectively treat prolapse of lumbar intervertebral disc, hyperosteogeny, allows patient's eliminate pain, and activity freely.
The technical solution used in the present invention is as follows:
Treat a Chinese medicine composition for prolapse of lumbar intervertebral disc, be made up of the raw material of following weight portion: Radix Angelicae Sinensis 50-70 part, Radix Paeoniae Alba 40-50 part, Radix Rehmanniae Preparata 55-65 part, Radix Achyranthis Bidentatae 35-45 part, Cortex Eucommiae 45-55 part, Radix Astragali 35-45 part, Radix Salviae Miltiorrhizae 25-35 part, Herba Cistanches 25-35 part, bar halberd 20-30 part, Radix Notoginseng 25-35 part.
Above-described a kind of Chinese medicine composition for the treatment of prolapse of lumbar intervertebral disc, is made up of the raw material of following weight portion: Radix Angelicae Sinensis 55-67 part, Radix Paeoniae Alba 43-48 part, Radix Rehmanniae Preparata 58-63 part, Radix Achyranthis Bidentatae 38-42 part, Cortex Eucommiae 47-53 part, Radix Astragali 38-43 part, Radix Salviae Miltiorrhizae 27-32 part, Herba Cistanches 28-32 part, bar halberd 23-27 part, Radix Notoginseng 28-33 part.
Above-described a kind of Chinese medicine composition for the treatment of prolapse of lumbar intervertebral disc, is made up of the raw material of following weight portion: Radix Angelicae Sinensis 58 parts, the Radix Paeoniae Alba 45 parts, 60 parts, Radix Rehmanniae Preparata, Radix Achyranthis Bidentatae 40 parts, the Cortex Eucommiae 51 parts, the Radix Astragali 40 parts, Radix Salviae Miltiorrhizae 29 parts, Herba Cistanches 31 parts, bar halberd 26 parts, Radix Notoginseng 29 parts.
Above-described a kind of Chinese medicine composition for the treatment of prolapse of lumbar intervertebral disc, is made up of the raw material of following weight portion: Radix Angelicae Sinensis 60 parts, the Radix Paeoniae Alba 46 parts, 58 parts, Radix Rehmanniae Preparata, Radix Achyranthis Bidentatae 42 parts, the Cortex Eucommiae 50 parts, the Radix Astragali 42 parts, Radix Salviae Miltiorrhizae 30 parts, Herba Cistanches 32 parts, bar halberd 25 parts, Radix Notoginseng 31 parts.
Above-described a kind of preparation method for the treatment of the Chinese medicine composition of prolapse of lumbar intervertebral disc, comprises the following steps:
(1) each raw medicinal material is taken according to weight portion;
(2) above-mentioned each raw medicinal material is dried, is ground into powder, fully mix in high-speed mixer;
(3) mixture in step (2) is sub-packed in sealing bag fast.
Further, in described step (2) by pulverizing medicinal materials to 150 order.
Further, the rotating speed of described step (2) high speed mixer is 200r/min.
Above-described a kind of preparation method for the treatment of the Chinese medicine composition of prolapse of lumbar intervertebral disc, is prepared into powder or ethanol extract.
Further, described in make ethanol extract for Chinese medicine composition being immersed in 2400 parts of Chinese liquor 15 days, wherein the alcoholic strength of Chinese liquor is 46 ° ~ 50 °.
The pharmacologically active of the Chinese crude drug that the present invention selects is as follows:
Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
The Radix Paeoniae Alba: have suppressing liver-YANG, nourishes blood and receives effect of the moon.Cure mainly feeling of fullness in the head, dizzy, tinnitus, irritable, menoxenia, dysmenorrhea, metrorrhagia, night sweat, costa sternales pain, carpopedal spasm pain.
Radix Rehmanniae Preparata: have YIN nourishing effect of enriching blood, can be used for the diseases such as blood deficiency and yellow complexion, dizzy, palpitation and insomnia, menoxenia, metrorrhagia, diseases such as also can be used for hectic fever hectic fever due to YIN-deficiency, the night sweat of deficiency of kidney yin, pass out semen, quench one's thirst.
Radix Achyranthis Bidentatae: invigorating the liver and kidney, bone and muscle strengthening, promoting blood circulation to restore menstrual flow, descending, inducing diuresis for treating stranguria syndrome of igniting.Cure mainly soreness of waist and knee joint, flaccidity and weakness of the lower limbs, amenorrhea due to stagnation of blood, dysmenorrhea, puerperal abdominal pain due to blood stasis, lump in the abdomen, retention of placenta, pyretic stranguria, stranguria with blood, traumatic injury, carbuncle malignant boil, laryngopharynx swelling and pain.
The Cortex Eucommiae: there is liver protecting and kidney invigorating, hypertension and hyperlipemia, enhancing immunity, relieving constipation diuresis, calm the nerves and support the effect such as dormancy.
The Radix Astragali: there is enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.Can not only coronary artery dilator, improve blood supply of cardiac muscle, improve immunologic function, and can the process of delaying cell aging.
Radix Salviae Miltiorrhizae: have blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, effect of removing heat from blood eliminating carbuncle.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, abdominal mass abdominal mass is gathered, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, and dysmenorrhea amenorrhea, skin infection swells and ache.
Herba Cistanches: kidney-replenishing, benefiting essence-blood, intestine moistening road.Cure mainly kidney yang deficiency, the sexual impotence of asthenia of essence and blood, seminal emission, nebulousurine, the frequent micturition heeltap, lumbago flaccidity of the lower limbs, tinnitus order is spent, phase, infertility, dryness of the intestine constipation are spread out in menstruation.
Ba Ji: kidney-replenishing, bone and muscle strengthening, wind-damp dispelling., menoxenia infertile for impotence and seminal emission, cold womb, few abdomen cold type of pain, rheumatic arthralgia, muscles and bones flaccidity are soft.Radix Morindae Officinalis Radix Morindae Officinalis can kidney-replenishing, benefiting essence-blood, bone and muscle strengthening, wind-damp dispelling.
Radix Notoginseng: dissipating blood stasis stops blooding, subduing swelling and relieving pain.For spitting of blood, haematemesis, epistaxis, have blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.
Beneficial effect of the present invention: Chinese medicine composition taking convenience of the present invention, the efficacy of a drug can be gone directly disease place, can improve local blood circulation rapidly, tendons relaxing and meridians dredging; Can effectively treat prolapse of lumbar intervertebral disc, hyperosteogeny, allow patient's eliminate pain, activity freely.Patient without the need to standing the pain of performing the operation and high cost, concerning Gospel especially middle-aged and elderly people.
Detailed description of the invention
Below by detailed description of the invention, the present invention is further elaborated, but should not be construed as limitation of the present invention.
Embodiment 1
Treat a Chinese medicine composition for prolapse of lumbar intervertebral disc, be made up of the raw material of following weight portion: Radix Angelicae Sinensis 58 parts, the Radix Paeoniae Alba 45 parts, 60 parts, Radix Rehmanniae Preparata, Radix Achyranthis Bidentatae 40 parts, the Cortex Eucommiae 51 parts, the Radix Astragali 40 parts, Radix Salviae Miltiorrhizae 29 parts, Herba Cistanches 31 parts, bar halberd 26 parts, Radix Notoginseng 29 parts.
Preparation method: (1) takes each raw medicinal material according to weight portion; (2) above-mentioned each raw medicinal material is dried, is ground into powder, fully mix in high-speed mixer; (3) step (2) gained mixture is sub-packed in sealing bag fast.Wherein, in described step (2) by pulverizing medicinal materials to 150 order; The rotating speed of high-speed mixer is 200r/min.
Embodiment 2
Treat a Chinese medicine composition for prolapse of lumbar intervertebral disc, be made up of the raw material of following weight portion: Radix Angelicae Sinensis 60 parts, the Radix Paeoniae Alba 46 parts, 58 parts, Radix Rehmanniae Preparata, Radix Achyranthis Bidentatae 42 parts, the Cortex Eucommiae 50 parts, the Radix Astragali 42 parts, Radix Salviae Miltiorrhizae 30 parts, Herba Cistanches 32 parts, bar halberd 25 parts, Radix Notoginseng 31 parts.
Preparation method: (1) takes each raw medicinal material according to weight portion; (2) above-mentioned each raw medicinal material is dried, is ground into powder, fully mix in high-speed mixer; (3) step (2) gained mixture is sub-packed in sealing bag fast.Wherein, in described step (2) by pulverizing medicinal materials to 150 order; The rotating speed of high-speed mixer is 200r/min.
Embodiment 3
Treat a Chinese medicine composition for prolapse of lumbar intervertebral disc, be made up of the raw material of following weight portion: Radix Angelicae Sinensis 55 parts, the Radix Paeoniae Alba 43 parts, 58 parts, Radix Rehmanniae Preparata, Radix Achyranthis Bidentatae 38 parts, the Cortex Eucommiae 47 parts, the Radix Astragali 38 parts, Radix Salviae Miltiorrhizae 27 parts, Herba Cistanches 28 parts, bar halberd 23 parts, Radix Notoginseng 28 parts.
Preparation method: (1) takes each raw medicinal material according to weight portion; (2) above-mentioned each raw medicinal material is dried, is ground into powder, fully mix in high-speed mixer; (3) step (2) gained mixture is sub-packed in sealing bag fast.Wherein, in described step (2) by pulverizing medicinal materials to 150 order; The rotating speed of high-speed mixer is 200r/min.
Embodiment 4
Treat a Chinese medicine composition for prolapse of lumbar intervertebral disc, be made up of the raw material of following weight portion: Radix Angelicae Sinensis 67 parts, the Radix Paeoniae Alba 48 parts, 63 parts, Radix Rehmanniae Preparata, Radix Achyranthis Bidentatae 42 parts, the Cortex Eucommiae 53 parts, the Radix Astragali 43 parts, Radix Salviae Miltiorrhizae 32 parts, Herba Cistanches 32 parts, bar halberd 27 parts, Radix Notoginseng 33 parts.
Preparation method: (1) takes each raw medicinal material according to weight portion; (2) above-mentioned each raw medicinal material is dried, is ground into powder, fully mix in high-speed mixer; (3) step (2) gained mixture is sub-packed in sealing bag fast.Wherein, in described step (2) by pulverizing medicinal materials to 150 order; The rotating speed of high-speed mixer is 200r/min.
Embodiment 5
Treat a Chinese medicine composition for prolapse of lumbar intervertebral disc, be made up of the raw material of following weight portion: Radix Angelicae Sinensis 67 parts, the Radix Paeoniae Alba 48 parts, 63 parts, Radix Rehmanniae Preparata, Radix Achyranthis Bidentatae 42 parts, the Cortex Eucommiae 53 parts, the Radix Astragali 43 parts, Radix Salviae Miltiorrhizae 32 parts, Herba Cistanches 32 parts, bar halberd 27 parts, Radix Notoginseng 33 parts.
Preparation method: Chinese medicine composition being immersed in 2400 parts of alcoholic strengths is in the Chinese liquor of 46 ° 15 days.
Embodiment 6
Treat a Chinese medicine composition for prolapse of lumbar intervertebral disc, be made up of the raw material of following weight portion: Radix Angelicae Sinensis 55 parts, the Radix Paeoniae Alba 43 parts, 58 parts, Radix Rehmanniae Preparata, Radix Achyranthis Bidentatae 38 parts, the Cortex Eucommiae 47 parts, the Radix Astragali 38 parts, Radix Salviae Miltiorrhizae 27 parts, Herba Cistanches 28 parts, bar halberd 23 parts, Radix Notoginseng 28 parts.
Preparation method: Chinese medicine composition being immersed in 2400 parts of alcoholic strengths is in the Chinese liquor of 50 ° 15 days.
Clinical practice example
Choose 300 routine prolapse of lumbar intervertebral disc patients, wherein female patient 138 example, male patient 162 example; 200 routine hyperosteogeny patients, wherein female patient 85 example, male patient 115 example, takes the Chinese medicine composition of embodiment 1, carries out statistical result.
Clinical symptoms and sign: prolapse of lumbar intervertebral disc patient main manifestations is flank pain, its pain dimensions is mainly at waist and lumbosacral region, the most common with persistent dull pain, and during horizontal position, pain can alleviate, and when erect position and seat, this pain can increase the weight of; Hyperosteogeny patient main manifestations is pain, swelling, limbs disturbance.
Using method: every day is early, middle and late respectively once, and each 10 grams, with mixing in water for oral taking, one month is a course for the treatment of; Heart disease, hyperpietic and anemia of pregnant woman's forbidding.
The standard of curative effect evaluation:
Recovery from illness: lumbago and skelalgia disappears, leg raising straight more than 70 degree, can recover normal work;
Take a turn for the better: lumbago and skelalgia alleviates, waist movable function improves;
Do not heal: symptom and sign is without improvement.
After taking three courses for the treatment of of Chinese medicine composition of embodiment 1, in 300 routine prolapse of lumbar intervertebral disc patients, recovery from illness 224 example, 71 examples that take a turn for the better, more 5 examples, total effective rate 98.3%; In 200 routine hyperosteogeny patients, recovery from illness 139 is routine, improvement 55 is routine, do not heal 6 examples, total effective rate 97%, as following table:
Disease Gross sample number Recovery from illness Take a turn for the better Do not heal Total effective rate
Prolapse of lumbar intervertebral disc 300 examples 224 examples 71 examples 5 examples 98.3%
Hyperosteogeny 200 examples 139 examples 55 examples 6 examples 97%
Visible, Chinese medicine composition of the present invention can effectively treat prolapse of lumbar intervertebral disc, hyperosteogeny, allows patient's eliminate pain, and activity freely.
Below model case of the present invention:
Mr. Wu, 52 years old, people from Chengdu, suffer from prolapse of lumbar intervertebral disc, hyperosteogeny 5 years, pressuring nerve, recurrence after operation, fully recovered after half a year of taking medicine, and whole body is without pain, and now existing 2 years, nothing recurred.
Mr. Ma, 60 years old, people from Chongqing, suffer from prolapse of lumbar intervertebral disc 10 years, dynamic two operations still rebounded, and take medicine and start after two months to leave the bed, after half a year, activity freely.
Mr. Jiang, 42 years old, people from Chengdu, suffered from prolapse of lumbar intervertebral disc, hyperosteogeny 3 years, fully recovers after half a year of taking medicine, without pain, without recurrence.

Claims (9)

1. treat the Chinese medicine composition of prolapse of lumbar intervertebral disc for one kind, it is characterized in that, be made up of the raw material of following weight portion: Radix Angelicae Sinensis 50-70 part, Radix Paeoniae Alba 40-50 part, Radix Rehmanniae Preparata 55-65 part, Radix Achyranthis Bidentatae 35-45 part, Cortex Eucommiae 45-55 part, Radix Astragali 35-45 part, Radix Salviae Miltiorrhizae 25-35 part, Herba Cistanches 25-35 part, bar halberd 20-30 part, Radix Notoginseng 25-35 part.
2. a kind of Chinese medicine composition for the treatment of prolapse of lumbar intervertebral disc according to claim 1, it is characterized in that, be made up of the raw material of following weight portion: Radix Angelicae Sinensis 55-67 part, Radix Paeoniae Alba 43-48 part, Radix Rehmanniae Preparata 58-63 part, Radix Achyranthis Bidentatae 38-42 part, Cortex Eucommiae 47-53 part, Radix Astragali 38-43 part, Radix Salviae Miltiorrhizae 27-32 part, Herba Cistanches 28-32 part, bar halberd 23-27 part, Radix Notoginseng 28-33 part.
3. a kind of Chinese medicine composition for the treatment of prolapse of lumbar intervertebral disc according to claim 1, it is characterized in that, be made up of the raw material of following weight portion: Radix Angelicae Sinensis 58 parts, the Radix Paeoniae Alba 45 parts, 60 parts, Radix Rehmanniae Preparata, Radix Achyranthis Bidentatae 40 parts, the Cortex Eucommiae 51 parts, the Radix Astragali 40 parts, Radix Salviae Miltiorrhizae 29 parts, Herba Cistanches 31 parts, bar halberd 26 parts, Radix Notoginseng 29 parts.
4. a kind of Chinese medicine composition for the treatment of prolapse of lumbar intervertebral disc according to claim 1, it is characterized in that, be made up of the raw material of following weight portion: Radix Angelicae Sinensis 60 parts, the Radix Paeoniae Alba 46 parts, 58 parts, Radix Rehmanniae Preparata, Radix Achyranthis Bidentatae 42 parts, the Cortex Eucommiae 50 parts, the Radix Astragali 42 parts, Radix Salviae Miltiorrhizae 30 parts, Herba Cistanches 32 parts, bar halberd 25 parts, Radix Notoginseng 31 parts.
5. a kind of preparation method for the treatment of the Chinese medicine composition of prolapse of lumbar intervertebral disc described in any one of claim 1-4, is characterized in that, comprise the following steps:
(1) each raw medicinal material is taken according to weight portion;
(2) above-mentioned each raw medicinal material is dried, is ground into powder, fully mix in high-speed mixer;
(3) mixture in step (2) is sub-packed in sealing bag fast.
6. a kind of preparation method for the treatment of the Chinese medicine composition of prolapse of lumbar intervertebral disc according to claim 5, is characterized in that, by pulverizing medicinal materials to 150 order in described step (2).
7. a kind of preparation method for the treatment of the Chinese medicine composition of prolapse of lumbar intervertebral disc according to claim 5, is characterized in that, the rotating speed of described step (2) high speed mixer is 200r/min.
8. a kind of preparation method for the treatment of the Chinese medicine composition of prolapse of lumbar intervertebral disc according to claim 5, is characterized in that, be prepared into powder or ethanol extract.
9. a kind of preparation method for the treatment of the Chinese medicine composition of prolapse of lumbar intervertebral disc according to claim 8, it is characterized in that, described ethanol extract of making is for being immersed in 2400 parts of Chinese liquor 15 days by Chinese medicine composition, wherein the alcoholic strength of Chinese liquor is 46 ° ~ 50 °.
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CN110141606A (en) * 2019-06-27 2019-08-20 眉山市中医医院(眉山市东坡区人民医院) A kind of Chinese medicine compound prescription for treating the cold-dampness type protrasion of the lumbar intervertebral disci
CN111939192A (en) * 2020-08-28 2020-11-17 凉山新鑫中药饮片有限公司 A Chinese medicinal composition for treating prolapse of lumbar intervertebral disc and hyperosteogeny, and its preparation method
CN114931607A (en) * 2022-02-23 2022-08-23 广州大医中医医院有限公司 Traditional Chinese medicine preparation for treating lumbar disc herniation pain and preparation method thereof

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110141606A (en) * 2019-06-27 2019-08-20 眉山市中医医院(眉山市东坡区人民医院) A kind of Chinese medicine compound prescription for treating the cold-dampness type protrasion of the lumbar intervertebral disci
CN111939192A (en) * 2020-08-28 2020-11-17 凉山新鑫中药饮片有限公司 A Chinese medicinal composition for treating prolapse of lumbar intervertebral disc and hyperosteogeny, and its preparation method
CN114931607A (en) * 2022-02-23 2022-08-23 广州大医中医医院有限公司 Traditional Chinese medicine preparation for treating lumbar disc herniation pain and preparation method thereof

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