CN104721313A - Nursing medicine for treating acute waist injury - Google Patents

Nursing medicine for treating acute waist injury Download PDF

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Publication number
CN104721313A
CN104721313A CN201510142017.5A CN201510142017A CN104721313A CN 104721313 A CN104721313 A CN 104721313A CN 201510142017 A CN201510142017 A CN 201510142017A CN 104721313 A CN104721313 A CN 104721313A
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water
treatment
care drug
acute lumbar
ointment
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CN104721313B (en
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不公告发明人
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Cui Chao
Zhang Yanhua
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Qingdao Yuntian Biotechnology Co Ltd
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Abstract

The invention belongs to the technical field of medicines, and particularly relates to a nursing medicine for treating an acute waist injury. The nursing medicine comprises the following components: astragalus membranaceus, rhizoma atractylodis, garden balsam stem, peach kernel, lycopodium clavatum, flos carthami, honeysuckle stem, achyranthes bidentata, panax notoginseng and rhizoma corydalis. The nursing medicine is reasonable in composition, simple in preparation process, convenient to take, obvious in curative effect and free of a side effect, and is an effective medicine for treating the acute waist injury.

Description

A kind of care drug for the treatment of acute lumbar injury
Technical field
The invention belongs to medical art, be specifically related to a kind of care drug for the treatment of acute lumbar injury.
Background technology
The main clinical characteristics of acute lumbar injury is waist severe pain, limitation of activity.How because labour posture is not good, waist muscle is imbalance firmly, powerfully bears a heavy burden, and turns round sudden strain of a muscle and falls and flutter, so that the tired resistance of QI and blood, and passages through which vital energy circulates runs smooth, and numbness hinders in waist, stagnation of QI and blood may bring about pain and causing.The lighter is musculus sacrospinalis and fascia thoracolumbalis damage in various degree; The damage of interspinal ligaments can be there is compared with severe one; It is disorderly to be there is incarcerated synovium posterior joint in severe patient.Modern medicine thinks that waist acute soft tissue injury is the local organization cellular swelling, and blood follows obstacle, and vein lymph is obstructed, harmful substance aggregation, caused by ischemic hypoxia and nerve compression.Motherland's medical science thinks not smooth through cave, and blood stasis swelling, blockage of main and collateral channels, muscles contracture can cause local qi depression to blood stasis pain and limitation of activity.Modern Chinese medicine theory research and development gained medicine is utilized to decrease side effects of pharmaceutical drugs to greatest extent, clear superiority is shown in safety, make it have good therapeutic effect, therefore develop determined curative effect, the Chinese medicine nursing medicine of the therapeutic dosage forms lumbar injury that patient compliance is good is necessary.
Summary of the invention
The present invention is by plus-minus taste on ancient prescription basis, and providing one, to have prescription rigorous, and compatibility science is evident in efficacy, can play curative effect of medication to greatest extent, and easy to prepare, and patient compliance is good, the care drug of the treatment acute lumbar injury had no side effect.
For achieving the above object, technical scheme provided by the invention is the care drug of described treatment acute lumbar injury, it is characterized in that described care drug is made up of the medicine of following weight proportion: Radix Astragali 18-22g, Rhizoma Atractylodis 14-16g, Herba speranskiae tuberculatae 18-22g, Semen Persicae 7-9g, Herba Lycopodii 18-22g, Flos Carthami 5-7g, Caulis Lonicerae 12-15g, Radix Achyranthis Bidentatae 12-15g, Radix Notoginseng 5-7g, Rhizoma Corydalis 12-15g.
Most preferred technique scheme of the present invention is that care drug of the present invention is obtained by the material medicine of following weight proportion: Radix Astragali 20g, Rhizoma Atractylodis 15g, Herba speranskiae tuberculatae 20g, Semen Persicae 8g, Herba Lycopodii 20g, Flos Carthami 6g, Caulis Lonicerae 13g, Radix Achyranthis Bidentatae 14g, Radix Notoginseng 6g, Rhizoma Corydalis 13g.
Described care drug is external preparation or oral formulations.
Care drug of the present invention is preferably prepared into external preparation.Be prepared into ointment, ointment or gel specifically.
When above-mentioned external preparation is ointment, its preparation method has the following steps: take above Chinese medicine component according to aforesaid weight and be ground into coarse powder respectively, add the water of medical material gross weight 10 times amount, decocting time is 4h, filters; Filtrate simmer down to clear paste, dry, pulverize into fine powder; Get glyceryl monostearate, stearic acid, white vaseline, triethanolamine heating in water bath to fusing, mixing, as oil phase; Get appropriate purified water, fine powder is dissolved in water; Get glycerol, sodium lauryl sulphate, purified water, ethyl hydroxybenzoate be mixed and heated to about 80 DEG C, as aqueous phase; When oil phase temperature is 80 DEG C, under stirring, fine powder solution is added wherein, and make temperature remain on 80 DEG C; By the oil phase after stirring, under low rate mixing, slowly add in aqueous phase, 30min is stirred in rear acceleration, stops stirring, obtains emulsifiable paste.
Above-mentioned external preparation is that the preparation method step of ointment is as follows: take above Chinese medicine component according to aforesaid weight and be ground into coarse powder respectively; Add the water of medical material gross weight 10 times amount, decocting time is 4h, filters; Filtrate simmer down to clear paste; Get paraffin, glyceryl monostearate, white vaseline, liquid Paraffin, propylene glycol, sorbester p17 and ethylparaben heat fused keep 80 DEG C in water-bath, slowly add the water of 80 DEG C under stirring, limit edged is stirred to condensation, i.e. ointment base; Qinghuo reagent is dissolved in appropriate purified water, joins in substrate, stirs, to obtain final product.
Above-mentioned oral formulations is that the preparation method step of gel is as follows: take above Chinese medicine component according to aforesaid weight and be ground into coarse powder respectively; Add the water of medical material gross weight 10 times amount, decocting time is 4h, filters; Filtrate simmer down to clear paste, cold drying, is ground into middle powder; Slowly be added to the water by carbomer, limit edged stirs until form transparent gel-type vehicle, is dissolved in suitable quantity of water by middle powder, then adds in substrate, stir, add propylene glycol, glycerol, water, and adjust ph, to neutral, to obtain final product.
Care drug of the present invention is prepared into the preparations such as tablet, capsule, drop pill, granule, powder and oral liquid and also creates good effect.
The present invention, relative to prior art, has following clear superiority:
First, care drug prescription of the present invention mainly develops according to the pathogenic characteristic of acute lumbar injury patient, evident in efficacy to qi stagnation and blood stasis type acute lumbar injury, and in side, Radix Astragali righting poison holding is got rid of evils; Rhizoma Atractylodis dispersing cold for relieving pain; Herba speranskiae tuberculatae, Herba Lycopodii relaxing muscles and tendons to promote blood circulation dredging collateral, Semen Persicae, Flos Carthami blood circulation promoting and blood stasis dispelling; The active easypro warp of Caulis Lonicerae; Radix Achyranthis Bidentatae, Radix Notoginseng, Rhizoma Corydalis blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain; Full side plays the merit of blood circulation promoting and blood stasis dispelling, soothing the channels and quicking the network vessels, regulating QI to relieve pain altogether.Extremely strong specific aim curative effect is had to acute lumbar injury.Through clinical practice checking, its determined curative effect, mild in medicine property and, do not occur toxic and side effects and untoward reaction, safety coefficient is high.Chinese medicine preparation of the present invention adopts advanced extraction equipment and technique, abundant effective component extracting, can be made into and facilitates Chinese medicine preparation that is oral or that carry.
Further, in care drug of the present invention, the function of each crude drug cures mainly:
The Radix Astragali, sweet, temperature.Return lung, spleen channel.Invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Rhizoma Atractylodis, pungent, bitter, temperature.Return spleen, stomach, Liver Channel.Drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, have loose bowels, edema, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia.
Herba speranskiae tuberculatae, pungent; Warm in nature.Lung; Liver Channel.Expelling wind and removing dampness; Relaxing muscles and tendons to promote blood circulation; Dissipating blood stasis for subsidence of swelling; Removing toxic substances ophthalmalgia.Main air pain of dampness syndrome; Muscles and bones contracture; The disturbance of lower legs due to pathogenic cold and dampness; Lumbar strain; Paralysis; Amenorrhea; Eczema scrotum; Furuncle toxic swelling.
Semen Persicae, bitter, sweet, flat.GUIXIN, liver, large intestine channel.Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.For amenorrhea, dysmenorrhea , WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.
Herba Lycopodii, micro-hardship, pungent, temperature.Return liver,spleen,kidney warp.Expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral.For joint aches, joint stuffiness.
Flos Carthami, pungent, temperature.GUIXIN, Liver Channel.Promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia , mass in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.
Caulis Lonicerae, sweet, cold.Attach to the lung and stomach meridians.Heat-clearing and toxic substances removing, dispelling wind dredging collateral.For epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle skin infection, beriberoid pyretic arthralgia, redness and swelling of joints burning pain.
Radix Achyranthis Bidentatae is bitter, sour, flat.Return liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards.For soreness of waist and knee joint, muscles and bones is unable, amenorrhea and mass in the abdomen, dizziness due to hyperactivity of liver-YANG.
Radix Notoginseng, sweet, micro-hardship, temperature.Return liver, stomach warp.Dissipating blood stasis stops blooding, subduing swelling and relieving pain.For spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, and breast abdomen twinges, tumbling and swelling.
Rhizoma Corydalis, pungent, bitter, temperature.Return liver, spleen channel.Invigorate blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.
The present invention also asks the purposes protecting above-mentioned care drug in the medicine of preparation treatment acute lumbar injury.In clinical observation process, treatment group and matched group is divided into treat at random 80 routine acute lumbar injury patients, after treatment group uses two courses for the treatment of of Drug therapy of the present invention, clinical effectiveness shows, after treatment group acute lumbar injury disease patient treatment, symptom can significantly improve.And body weight, heart rate, blood pressure, hepatic and renal function are showed no obvious change before and after treatment group treatment.Treatment group does not find the obvious adverse events such as irritated in whole therapeutic process.Result shows that the clinical application of we is safely and effectively, is worth studying and applying further.
Detailed description of the invention
Further describe the present invention below by way of specific embodiment, but the present invention is not limited only to following specific embodiment.Within the scope of the invention or not departing from content of the present invention, spirit and scope, the change carried out the present invention, combination or replacement, be apparent for a person skilled in the art, and be included within the scope of the present invention.
Embodiment 1 ointment
The each raw material of the present invention is taken: Radix Astragali 20g, Rhizoma Atractylodis 15g, Herba speranskiae tuberculatae 20g, Semen Persicae 8g, Herba Lycopodii 20g, Flos Carthami 6g, Caulis Lonicerae 13g, Radix Achyranthis Bidentatae 14g, Radix Notoginseng 6g, Rhizoma Corydalis 13g by following weight proportion.
Preparation technology is as follows:
Take above Chinese medicine component according to aforesaid weight and be ground into coarse powder respectively, add the water of medical material gross weight 10 times amount, decocting time is 4h, filters; Filtrate simmer down to clear paste, dry, pulverize into fine powder;
Get 45g glyceryl monostearate, 110g stearic acid, 100g white vaseline, 15g triethanolamine heating in water bath to fusing, mixing, as oil phase; Get appropriate purified water, 340g fine powder is dissolved in water; Get 20g glycerol, 10g sodium lauryl sulphate, in right amount purified water, 3g ethyl hydroxybenzoate are mixed and heated to about 80 DEG C, as aqueous phase; When oil phase temperature is 80 DEG C, under stirring, fine powder solution is added wherein, and make temperature remain on 80 DEG C; By the oil phase after stirring, under low rate mixing, slowly add in aqueous phase, 30min is stirred in rear acceleration, stops stirring, obtains 1000g emulsifiable paste.
Use care drug of the present invention treat acute lumbar injury time, use prepared ointment, often prop up 15g, every day 2-3 even application affected part.
Embodiment 2 ointment
The each raw material of the present invention is taken: Radix Astragali 20g, Rhizoma Atractylodis 15g, Herba speranskiae tuberculatae 20g, Semen Persicae 8g, Herba Lycopodii 20g, Flos Carthami 6g, Caulis Lonicerae 13g, Radix Achyranthis Bidentatae 14g, Radix Notoginseng 6g, Rhizoma Corydalis 13g by following weight proportion.
Preparation technology is as follows:
Take above Chinese medicine component according to aforesaid weight and be ground into coarse powder respectively; Add the water of medical material gross weight 10 times amount, decocting time is 4h, filters; Filtrate simmer down to clear paste;
Get 100g paraffin, 100g glyceryl monostearate, 45g white vaseline, 55g liquid Paraffin, 50g propylene glycol, 4g sorbester p17 and 1g ethylparaben heat fused keep 80 DEG C in water-bath, the water of 80 DEG C is slowly added under stirring, limit edged is stirred to condensation, i.e. ointment base; Get 200g clear paste to be dissolved in appropriate purified water, join in substrate, stir, obtain 1000g ointment.
Use care drug of the present invention treat acute lumbar injury time, use prepared ointment, often prop up 15g, every day 3-4 even application affected part.
Embodiment 3 gel
The each raw material of the present invention is taken: Radix Astragali 20g, Rhizoma Atractylodis 15g, Herba speranskiae tuberculatae 20g, Semen Persicae 8g, Herba Lycopodii 20g, Flos Carthami 6g, Caulis Lonicerae 13g, Radix Achyranthis Bidentatae 14g, Radix Notoginseng 6g, Rhizoma Corydalis 13g by following weight proportion.
Preparation technology is as follows:
Take above Chinese medicine component according to aforesaid weight and be ground into coarse powder respectively; Add the water of medical material gross weight 10 times amount, decocting time is 4h, filters; Filtrate simmer down to clear paste, cold drying, is ground into fine powder;
Slowly be added to the water by 12g carbomer, limit edged stirs until form transparent gel-type vehicle, by soluble in water for 340g fine powder, add again in gel-type vehicle, stir, add 60mL propylene glycol, 50mL glycerol, suitable quantity of water to 1000g, appropriate triethanolamine adjust ph, to neutral, to obtain final product.
Use care drug of the present invention treat acute lumbar injury time, use prepared gel, often prop up 15g, every day 2-3 even application affected part.
Embodiment 4
The each raw material of the present invention is taken: Radix Astragali 18g, Rhizoma Atractylodis 14g, Herba speranskiae tuberculatae 18g, Semen Persicae 7g, Herba Lycopodii 18g, Flos Carthami 5g, Caulis Lonicerae 12g, Radix Achyranthis Bidentatae 12g, Radix Notoginseng 5g, Rhizoma Corydalis 12g by following weight proportion.
Preparation technology is with embodiment 1.
Embodiment 5
The each raw material of the present invention is taken: Radix Astragali 22g, Rhizoma Atractylodis 16g, Herba speranskiae tuberculatae 22g, Semen Persicae 9g, Herba Lycopodii 22g, Flos Carthami 7g, Caulis Lonicerae 15g, Radix Achyranthis Bidentatae 15g, Radix Notoginseng 7g, Rhizoma Corydalis 15g by following weight proportion.
Preparation technology is with embodiment 1.
The clinical observation of embodiment 6 care drug treatment of the present invention acute lumbar injury
1, case-data: select hospital outpatient acute lumbar injury patient 80 example.There is lumbar strain history, be more common in person between twenty and fifty.Waist one or both sides have an intense pain, limitation of activity, can not stand up, sitting and walking, often keep certain forced attitude, to reduce pain.Psoas muscle and buttocks muscular spasm, maybe can touch streak hard shape, damage location has obvious pressure pain point, and spinal column physiologic radian changes.Through x-ray inspection, get rid of the diseases such as prolapse of lumbar intervertebral disc.Qi stagnation and blood stasis type acute lumbar injury disease is seen: after sprain and contusion and brute force are born a heavy burden, waist has an intense pain, psoas muscle spasm, and waist can not be straight and upright, and difficulty of changing one's position is bent and stretched in pitching.Tongue is dark red or have petechia, thin fur, stringy and tense pulse.80 routine acute lumbar injury patients are divided into treatment group and matched group at random, often organize 40 examples.Treatment group man 28 example, female 12 example, 20 ~ 55 years old age; The course of disease 2 ~ 8 days, average 5 days.Matched group man 27 example, female 13 example, 21 ~ 55 years old age; The course of disease 1 ~ 7 day, average 5 days.Between two groups in sex, age, the course of disease etc. there was no significant difference (P > 0.05), there is comparability.
2, usage and dosage:
Treatment group: use ointment prepared by the embodiment of the present invention 1, behind warm water cleaning affected part, get appropriate evenly external application affected part, soft 2-3 minute, 3 times/day 3 days is 1 course for the treatment of.
Matched group: give YAOTONGNING JIAONANG, each 3, every day 3 times, oral.
Observe clinical therapeutic efficacy after 6 days for two groups.
3, efficacy determination:
Recovery from illness: flank pain disappears completely, and waist activity freely;
Effective: waist severe pain disappears, but still have slight aching and tired discomfort sensation, waist activity is freely;
Effective: waist severe pain is alleviated, and patient can stand pain, but still have obvious pain when waist is movable;
Invalid: before and after treatment, symptom is without improvement.
4, therapeutic effect:
In clinical observation process, 80 routine patients all complete clinical observation.Two groups of clinical effectiveness compare, treatment group clinical recovery cure rate 67.5%, total effective rate 97.5%, and clinical effectiveness is remarkable; Matched group clinical recovery rate 45%, total effective rate 72.5%.Two groups of total effective rates compare, and treatment group is significantly better than matched group, and especially treatment group clinical effectiveness in cure rate aspect is more remarkable.Concrete outcome is in table 1.
A table 1. liang group clinical effectiveness compares
Group Recovery from illness Effective Effectively Invalid
Treatment group 27 11 1 1
Matched group 18 6 5 11
The above results shows, after the care drug treatment of acute lumbar injury disease patient the application of the invention, symptom can significantly improve.In addition, rear body weight, heart rate, blood pressure, hepatic and renal function are showed no obvious change to treatment group before the treatment.Treatment group does not find the obvious adverse events such as irritated in whole therapeutic process.Result shows that the clinical application of we is safely and effectively, is worth studying and applying further.

Claims (9)

1. treat the care drug of acute lumbar injury for one kind, it is characterized in that, the composition of its primary raw material medicine and proportioning are: Radix Astragali 18-22g, Rhizoma Atractylodis 14-16g, Herba speranskiae tuberculatae 18-22g, Semen Persicae 7-9g, Herba Lycopodii 18-22g, Flos Carthami 5-7g, Caulis Lonicerae 12-15g, Radix Achyranthis Bidentatae 12-15g, Radix Notoginseng 5-7g, Rhizoma Corydalis 12-15g.
2. a kind of care drug for the treatment of acute lumbar injury as claimed in claim 1, it is characterized in that, the composition of its primary raw material medicine and proportioning are: Radix Astragali 20g, Rhizoma Atractylodis 15g, Herba speranskiae tuberculatae 20g, Semen Persicae 8g, Herba Lycopodii 20g, Flos Carthami 6g, Caulis Lonicerae 13g, Radix Achyranthis Bidentatae 14g, Radix Notoginseng 6g, Rhizoma Corydalis 13g.
3. a kind of care drug for the treatment of acute lumbar injury as described in claim 1,2, it is characterized in that, described care drug is external preparation.
4. a kind of care drug for the treatment of acute lumbar injury as claimed in claim 3, it is characterized in that, described external preparation is ointment, ointment or gel.
5. a kind of care drug for the treatment of acute lumbar injury as claimed in claim 4, it is characterized in that, the preparation method of described ointment has the following steps: take above Chinese medicine component according to aforesaid weight and be ground into coarse powder respectively, add the water of medical material gross weight 10 times amount, decocting time is 4h, filters; Filtrate simmer down to clear paste, dry, pulverize into fine powder; Get glyceryl monostearate, stearic acid, white vaseline, triethanolamine heating in water bath to fusing, mixing, as oil phase; Get appropriate purified water, fine powder is dissolved in water; Get glycerol, sodium lauryl sulphate, purified water, ethyl hydroxybenzoate be mixed and heated to about 80 DEG C, as aqueous phase; When oil phase temperature is 80 DEG C, under stirring, fine powder solution is added wherein, and make temperature remain on 80 DEG C; By the oil phase after stirring, under low rate mixing, slowly add in aqueous phase, 30min is stirred in rear acceleration, stops stirring, obtains ointment.
6. a kind of care drug for the treatment of acute lumbar injury as claimed in claim 4, it is characterized in that, the preparation method of described ointment has the following steps: take above Chinese medicine component according to aforesaid weight and be ground into fine powder respectively; Add the water of medical material gross weight 10 times amount, decocting time is 4h, filters; Filtrate simmer down to clear paste; Get paraffin, glyceryl monostearate, white vaseline, liquid Paraffin, propylene glycol, sorbester p17 and ethylparaben heat fused keep 80 DEG C in water-bath, slowly add the water of 80 DEG C under stirring, limit edged is stirred to condensation, i.e. ointment base; Qinghuo reagent is dissolved in appropriate purified water, joins in substrate, stirs, to obtain final product.
7. a kind of care drug for the treatment of acute lumbar injury as claimed in claim 4, it is characterized in that, the preparation method of described gel has the following steps: take above Chinese medicine component according to aforesaid weight and be ground into fine powder respectively; Add the water of medical material gross weight 10 times amount, decocting time is 4h, filters; Filtrate simmer down to clear paste, cold drying, is ground into middle powder; Slowly be added to the water by carbomer, limit edged stirs until form transparent gel-type vehicle, is dissolved in suitable quantity of water by middle powder, then adds in substrate, stir, add propylene glycol, glycerol, water, and adjust ph, to neutral, to obtain final product.
8. the purposes of the medicine as described in claim 1,2 in the care drug of preparation treatment acute lumbar injury.
9. the purposes of the medicine as described in claim 1,2 in the care drug of preparation treatment qi stagnation and blood stasis type acute lumbar injury.
CN201510142017.5A 2015-03-27 2015-03-27 A kind of care drug for the treatment of acute lumbar injury Expired - Fee Related CN104721313B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106110245A (en) * 2016-07-04 2016-11-16 吴先青 A kind of pharmaceutical composition treating lumbar injury
CN106109739A (en) * 2016-06-29 2016-11-16 邱定武 A kind of medicine cake treating waist injury and preparation method thereof

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CN101623346A (en) * 2008-07-08 2010-01-13 韩俊峰 Chinese medicinal composition for treating acute lumbar injury
CN103585413A (en) * 2013-11-08 2014-02-19 江龙 Medicine for external application for treating traumatic injuries

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106109739A (en) * 2016-06-29 2016-11-16 邱定武 A kind of medicine cake treating waist injury and preparation method thereof
CN106110245A (en) * 2016-07-04 2016-11-16 吴先青 A kind of pharmaceutical composition treating lumbar injury

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