CN100482674C - 皮肤瘢痕形成的减少 - Google Patents

皮肤瘢痕形成的减少 Download PDF

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Publication number
CN100482674C
CN100482674C CNB2004800406132A CN200480040613A CN100482674C CN 100482674 C CN100482674 C CN 100482674C CN B2004800406132 A CNB2004800406132 A CN B2004800406132A CN 200480040613 A CN200480040613 A CN 200480040613A CN 100482674 C CN100482674 C CN 100482674C
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China
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rad
cip1
waf1
wound
purposes
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Expired - Fee Related
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CNB2004800406132A
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English (en)
Chinese (zh)
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CN1906205A (zh
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D·古
M·泽佩达
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Canji Inc
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Canji Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CNB2004800406132A 2003-11-24 2004-11-23 皮肤瘢痕形成的减少 Expired - Fee Related CN100482674C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52499303P 2003-11-24 2003-11-24
US60/524,993 2003-11-24

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN2009101287188A Division CN101507822B (zh) 2003-11-24 2004-11-23 皮肤瘢痕形成的减少

Publications (2)

Publication Number Publication Date
CN1906205A CN1906205A (zh) 2007-01-31
CN100482674C true CN100482674C (zh) 2009-04-29

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Family Applications (2)

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CNB2004800406132A Expired - Fee Related CN100482674C (zh) 2003-11-24 2004-11-23 皮肤瘢痕形成的减少
CN2009101287188A Expired - Fee Related CN101507822B (zh) 2003-11-24 2004-11-23 皮肤瘢痕形成的减少

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CN2009101287188A Expired - Fee Related CN101507822B (zh) 2003-11-24 2004-11-23 皮肤瘢痕形成的减少

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Country Link
US (3) US7465442B2 (enExample)
EP (1) EP1692154A4 (enExample)
JP (2) JP4842139B2 (enExample)
KR (1) KR101167330B1 (enExample)
CN (2) CN100482674C (enExample)
AU (1) AU2004293474B2 (enExample)
BR (1) BRPI0416920A (enExample)
CA (1) CA2546287C (enExample)
IL (1) IL175603A (enExample)
NO (1) NO20062978L (enExample)
NZ (1) NZ546983A (enExample)
WO (1) WO2005051971A1 (enExample)
ZA (1) ZA200604147B (enExample)

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CN100482674C (zh) * 2003-11-24 2009-04-29 坎吉有限公司 皮肤瘢痕形成的减少
AU2009205429A1 (en) 2008-01-14 2009-07-23 Conventus Orthopaedics Inc. Apparatus and methods for fracture repair
US8796443B2 (en) 2008-09-22 2014-08-05 Rxi Pharmaceuticals Corporation Reduced size self-delivering RNAi compounds
EP2523614A4 (en) 2010-01-15 2017-02-15 Conventus Orthopaedics, Inc. Rotary-rigid orthopaedic rod
CN105534561B (zh) 2010-01-20 2018-04-03 康文图斯整形外科公司 用于骨接近和骨腔准备的装置及方法
JP2013521880A (ja) 2010-03-08 2013-06-13 コンベンタス オーソピディックス， インコーポレイテッド 骨インプラントを固定するための装置および方法
KR20180044433A (ko) 2010-03-24 2018-05-02 알엑스아이 파마슈티칼스 코포레이션 진피 및 섬유증성 적응증에서의 ｒｎａ 간섭
EP3077050B1 (en) * 2013-12-04 2020-10-21 Phio Pharmaceuticals Corp. Methods for treatment of wound healing utilizing chemically modified oligonucleotides
AU2014362251B2 (en) 2013-12-12 2019-10-10 Conventus Orthopaedics, Inc. Tissue displacement tools and methods
US10900039B2 (en) 2014-09-05 2021-01-26 Phio Pharmaceuticals Corp. Methods for treating aging and skin disorders using nucleic acids targeting Tyr or MMP1
SG11201808704YA (en) 2016-04-14 2018-11-29 Trizell Ltd Viral vector stabilization
WO2019010252A2 (en) 2017-07-04 2019-01-10 Conventus Orthopaedics, Inc. Apparatus and methods for treatment of a bone

Citations (1)

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US20020111304A1 (en) * 2000-12-01 2002-08-15 Andrius Kazlauskas Methods and compositions for treating fibrotic diseases

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Publication number Publication date
KR20060127414A (ko) 2006-12-12
IL175603A (en) 2011-02-28
NZ546983A (en) 2009-05-31
EP1692154A4 (en) 2009-07-08
CN101507822B (zh) 2012-06-06
JP2007512377A (ja) 2007-05-17
AU2004293474A1 (en) 2005-06-09
JP4842139B2 (ja) 2011-12-21
ZA200604147B (en) 2007-11-28
US7465442B2 (en) 2008-12-16
WO2005051971A1 (en) 2005-06-09
US20090142397A1 (en) 2009-06-04
NO20062978L (no) 2006-06-26
AU2004293474B2 (en) 2010-12-23
CN101507822A (zh) 2009-08-19
US20050271623A1 (en) 2005-12-08
US20110129534A1 (en) 2011-06-02
US8329671B2 (en) 2012-12-11
BRPI0416920A (pt) 2007-01-23
JP2011207912A (ja) 2011-10-20
EP1692154A1 (en) 2006-08-23
CA2546287C (en) 2014-04-22
KR101167330B1 (ko) 2012-07-23
CA2546287A1 (en) 2005-06-09
CN1906205A (zh) 2007-01-31
IL175603A0 (en) 2006-09-05

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Granted publication date: 20090429

Termination date: 20161123