CN100464783C - 一种含抗肿瘤抗生素的抗癌药物组合物 - Google Patents
一种含抗肿瘤抗生素的抗癌药物组合物 Download PDFInfo
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- CN100464783C CN100464783C CNB2004100360978A CN200410036097A CN100464783C CN 100464783 C CN100464783 C CN 100464783C CN B2004100360978 A CNB2004100360978 A CN B2004100360978A CN 200410036097 A CN200410036097 A CN 200410036097A CN 100464783 C CN100464783 C CN 100464783C
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Abstract
Description
瘤细胞 | Val | mDox | AD312 | ACLA | Piro | Am | Eso | mAMSA | IDA |
CNS | 68% | 64% | 62% | 66% | 76% | 64% | 62% | 66% | 67% |
C6 | 62% | 64% | 76% | 60% | 74% | 64% | 66% | 60% | 64% |
SA | 60% | 60% | 68% | 56% | 72% | 60% | 66% | 66% | 72% |
BC | 52% | 64% | 74% | 54% | 74% | 54% | 64% | 64% | 74% |
BA | 50% | 62% | 68% | 62% | 62% | 52% | 66% | 62% | 72% |
LH | 62% | 58% | 72% | 62% | 62% | 68% | 72% | 62% | 62% |
PAT | 58% | 56% | 74% | 66% | 62% | 66% | 74% | 66% | 64% |
试验组(n) | 所受治疗 | 肿瘤体积(cm<sup>3</sup>) | P值 |
1(6) | 对照 | 78.5±23cm<sup>3</sup> | |
2(6) | IDA | 62±4.3cm<sup>3</sup> | <0.05 |
3(6) | mDox | 50±2.5cm<sup>3</sup> | <0.01 |
4(6) | ACLA | 40±3.6cm<sup>3</sup> | <0.01 |
5(6) | Am | 42±4cm<sup>3</sup> | <0.01 |
6(6) | mAMSA | 42±3.8cm<sup>3</sup> | <0.01 |
7(6) | IDA+mDox | 22+3.6cm<sup>3</sup> | <0.001 |
8(6) | IDA+ACLA | 20±3.6cm<sup>3</sup> | <0.001 |
9(6) | IDA+Am | 20±3.6cm<sup>3</sup> | <0.001 |
10(6) | IDA+mAMSA | 18±3.6cm<sup>3</sup> | <0.001 |
试验组(n) | 所受治疗 | 肿瘤体积(cm<sup>3</sup>) | P值 |
1(6) | 对照 | 80±21cm<sup>3</sup> | |
2(6) | 奥柔比星 | 54±5cm<sup>3</sup> | <0.05 |
3(6) | 表柔比星 | 48±2.5cm<sup>3</sup> | <0.01 |
4(6) | 依索比星 | 44±3.2cm<sup>3</sup> | <0.01 |
5(6) | 伊达比星 | 48±3.6cm<sup>3</sup> | <0.01 |
6(6) | 流柔比星 | 40±3.8cm<sup>3</sup> | <0.01 |
7(6) | 奥柔比星+表柔比星 | 30±3.2cm<sup>3</sup> | <0.001 |
8(6) | 奥柔比星+依索比星 | 34±3.6cm<sup>3</sup> | <0.001 |
9(6) | 奥柔比星+伊达比星 | 22±3.2cm<sup>3</sup> | <0.001 |
10(6) | 奥柔比星+流柔比星 | 20±3.4cm<sup>3</sup> | <0.001 |
试验组(n) | 所受治疗 | 肿瘤体积(cm<sup>3</sup>) | P值 |
1(6) | 对照 | 88±2 | |
2(6) | 奥柔比星(ip) | 48±5.3 | <0.05 |
3(6) | 奥柔比星(it) | 58±2.3 | <0.01 |
4(6) | 奥柔比星(itp) | 56±3.4 | <0.01 |
5(6) | 表柔比星(ip) | 48±3.0 | <0.01 |
6(6) | 表柔比星(it) | 44±3.0 | <0.01 |
7(6) | 表柔比星(itp) | 33±3.0 | <0.001 |
8(6) | 依索比星(ip) | 32±3.6 | <0.001 |
9(6) | 依索比星(it) | 24±3.6 | <0.001 |
10(6) | 依索比星(itp) | 18±3.6 | <0.001 |
Claims (3)
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