CN100425159C - Health food and its preparing method - Google Patents
Health food and its preparing method Download PDFInfo
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- CN100425159C CN100425159C CNB200610097230XA CN200610097230A CN100425159C CN 100425159 C CN100425159 C CN 100425159C CN B200610097230X A CNB200610097230X A CN B200610097230XA CN 200610097230 A CN200610097230 A CN 200610097230A CN 100425159 C CN100425159 C CN 100425159C
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Abstract
The invention relates to a medicinal tonic in the field of traditional Chinese medicine, specifically to be concerned with a tonic which consists of American ginseng, dark plum and date.
Description
Technical field
The present invention relates to the traditional Chinese medicine health care product field, be specifically related to a kind of health food of forming by American Ginseng, dark plum, date.
Background technology
American Ginseng is cold in nature, sweet, little hardship of distinguishing the flavor of, the thoughts of returning home, lung, kidney channel, tool boosting qi and nourishing yin, the effect of promoting the production of body fluid of relieving inflammation or internal heat." new compilation of materia medica " thinks American Ginseng " fire falls in tonifying lung, last body fluid, relieving restlessness is tired, and is empty and have the fiery person suitable "; " book on Chinese herbal medicine is new again " also puts down in writing American Ginseng " it is prosperous to control lung-fire, coughing with a lot of sputum, the deficiency of vital energy breathes out to breathe heavily, the internal lesion caused by overexertion of losing blood, controlling nocturnal emission with astringent drugs is calmed the nerves, and produces all void "; " Records of Tradition Chinese and Western Medicine in Combination " then specifies " American Ginseng is cool in nature and mend, and all desires are not subjected to the warm person of genseng with genseng, all can this generation it ".
Dark plum is flat, and liver, spleen, lung, large intestine channel are returned in flavor acid, and tool promotes the production of body fluid, and astringes the lung, puckery intestines effect, and the available abnormal heat polydipsia of controlling, chronic cough rushes down for a long time." herbal classic " record dark plum " therapeutic method to keep the adverse qi flowing downward, the heat extraction dysphoria is felt at ease "; Supplement to the Herbal discovery dark plum is arrogated to oneself " quenching the thirst "; " book on Chinese herbal medicine meets former " then introduced all-sidely and said " dark plum acid is received, the smart appetizing of benefit, the puckery intestines of astringing the lung, preventing or arresting vomiting arrest sweating, Dingchuan ".
Date is warm in nature, and it is sweet to distinguish the flavor of, and returns spleen, stomach warp, tool tonifying middle-Jiao and Qi, nourishing blood and tranquilization effect." herbal classic " record date " is reposed in the peace, is mended the few Tianjin of weak breath, be not enough, frightened in the body "; " Japan hanako materia medica " illustrates date " the profit cardiopulmonary are only coughed, and tonifying five zang organs is controlled deficiently, removes stomach Bleach gas "; " drug regimen resembles " adds " date, transfer battalion defend born fluid " especially; The tradition nutrition points out that then date can " support spleen, strong will ".
Motherland's medical science is thought, heart master blood, main gods, " heart is the monarch of the whole body, reports empty order and contains good fortune; tool one reason is with Ying Wanji, and is very intelligent, there's no one who doesn't or isn't by it ", and " heart is the master of internal organs; and presidential soul, and this will ", the heart is described aspect spirit, intelligence, memory, play an important role.Again according to " essence, gas, god " theory, " refreshing gives birth to " by vital essence, and the change of vital essence and blood and body fluid life, move relevant, so essence, gas, blood, body fluid all are the material bases of the mind.Because of The spleen has the function to transport and transform nutrients be source of generating QI and blood, the breathing of lung governing qi department, so kidney storing essence life marrow is the dirty function of can assisting indirectly that The heart controls mental activities of spleen, lung, kidney three.
If the heart, spleen, lung, the damage of suffering from a deficiency of the kidney cause the motive, insufficiency of heart yin, then the gods owner of lost property.Deficiency of heart-QI, the refreshing gas that loses is supported, and the gods owner of lost property loses house, and is then absent-minded, incoherent; Or it is confused and worried and normal bosom frightened, being about to cry due to sadness.The heart-yin comprises the heart-yin Tianjin and painstaking effort, insufficiency of heart yin, and gods are lost and are supported and disturbance of deficiency-heat inside the body, palpitaition, insomnia, forgetful, dreaminess can occur.Non-boosting qi and nourishing yin can not make the gods winner.
Summary of the invention
The present invention is made up of natural food American Ginseng, dark plum, date.American Ginseng is the root of Araliaceae American Ginseng (Panaxquinquefolium L); Dark plum is the processing smoked product of the immature fruit (green plum) of rosaceae plant deciduous tree plum (Prunus mume (Sieb.) Sieb.et.Zucc.); Date is the ripening fruits of Rhamnaceae machaka or dungarunga plant jujube tree (Ziziphus jujubaMill.var.inermis (Bge.) Rehd.).These three kinds of natural foods since ancient times always generally as the medicine-food two-purpose product, both can be used for health care, can be used for disease preventing and treating again, thereby it is furtherd investigate as health food.
This prescription is principal component with the American Ginseng, and boosting qi and nourishing yin relieves inflammation or internal heat and promotes the production of body fluid, and makes the gods winner.American Ginseng and dark plum share, but sour-sweet herbs nourishing yin, the merit of enhancing American Ginseng nourishing Yin and promoting production of body fluid; American Ginseng and date share, and can strengthening the spleen and tonifying the lung, and make essence-QI from water and grain close the angry blood of clear gasification of nature, strengthen the merit of American Ginseng benefiting qi and nourishing blood.The three share, and essence, gas, blood, body fluid are enriched and the strong will of reposing, and can make clear and tranquilizing the mind in the fire of deficiency type again.
Technical scheme of the present invention is as follows:
Health food of the present invention (claiming the energy particle again) is made up of for 2～20 parts 3～6 parts of American Ginsengs, 3～10 parts of dark plums, date.Be weight portion.Preferred weight ratio is: 2～3 parts of American Ginsengs, 2～3 parts of dark plums, 4～6 parts in date.Further preferred weight ratio is: 1 part of American Ginseng, 1 part of dark plum, 2 parts in date.Except the composition of above-mentioned three kinds health-care effects, can also contain other pharmaceutical adjunct.
The preparation method of health food of the present invention comprises: American Ginseng, dark plum and date water or ethanol heating are extracted (backflow), concentrate, be drying to obtain.
Test is found, American Ginseng is heated extraction, concentrated, dry separately, concentrated with the extraction of dark plum and date again, dried powder, the health food health care of gained stronger (promptly hereinafter described branch is fried in shallow oil) like this.Therefore, the present invention preferably heats American Ginseng separately extraction, concentrated, dry, and the extract with dark plum and date mixes again.
Test is found, be better than water with the health food health care for preparing behind the alcohol extract and extract the health food that makes, so the present invention preferably to extract solvent be ethanol.
Further preferred manufacturing procedure comprises: with American Ginseng alcohol extract, concentrated, dry, dark plum and date remerge with alcohol extract, concentrated, dry.Concentration of ethanol is preferably 30～95%.
Usually, the present invention adopts following method: American Ginseng, dark plum and date are doubly measured alcohol heating reflux with 2-20 respectively and are extracted 1-3 time, each 0.5-2 hour, filter, merge secondary filtrate respectively, be evaporated to an amount of spray-dried separately and become fine powder, merge two kinds of fine powders, mixing, add right amount of auxiliary materials, granulate, can capsule or compressing tablet, promptly.Described auxiliary material has compressing tablet filler, wetting agent/adhesive, disintegrant and lubricant etc., or hard shell capsules diluent and lubricant etc.
Be the pharmacology test of part health care below:
The animal male ICR mouse, 18-22g is provided by west, Shanghai pul-Bi Kai animal used as test Co., Ltd.
Instrument passive avoidance reflectometer is developed by China Academy Of Traditional Chinese Medicine Traditional Chinese Medicine Research Institute, and behaviouristics is tested 1.0 softwares and carried out data acquisition.This device divides light and shade two Room.Bright chamber size is 11cm * 3.2cm, its outstanding 40w tungsten filament in about 20cm place, top.The darkroom is bigger, and size is 17cm * 3.2cm, and the round hole of the about 3cm of a diameter is arranged between two Room.All spread with the copper grid bottom, two Room.The copper grid in centre position, bottom, darkroom can be switched on, and electric shock intensity can be selected arbitrarily on a knob.The darkroom links to each other with a timer, and timer can write down the preclinical time automatically.
Statistical analysis uses NDST4.4 software to add up, and data are represented with x ± s.
Method and result
One, anoxia tolerance function is investigated:
The ICR mouse is divided into 7 groups at random: normal group, water extract (close and fry in shallow oil) group, water extract (branch is fried in shallow oil) group, alcohol extract (close and fry in shallow oil) group, alcohol extract (branch is fried in shallow oil) group, American Ginseng alcohol extract group, dark plum+date alcohol extract group.The weight ratio of three components in the extract: 1 part of American Ginseng, 1 part of dark plum, 2 parts in date.Close that to fry in shallow oil be the health food that three components mix to be extracted the back gained, divide to fry in shallow oil merging the health food of back gained with extract of other two flavors to American Ginseng extracts the back separately.Alcohol extract represents to use alcohol extract.
Per os is tried thing 3d continuously, 1h after last is tried thing, each group mouse is put into the 250mL wide-mouth bottle (only putting 1 mouse for every bottle) that fills the 15g soda lime respectively, smear bottleneck with vaseline, cover completely, make it air tight, immediately timing, with the breath stopped is index, observes mouse because of the dead time of anoxic.
The different extracts of table 1 to ICR mouse normal pressure resisting oxygen lack (x ± s, n=7)
*Compare with normal group P＜0.05;
Table 2 minute fry in shallow oil alcohol extract to ICR mouse normal pressure resisting oxygen lack (x ± s, n=7)
*Compare with normal group P＜0.05;
The result shows, gives animal 6 kinds of extracts than short-term (3d), and other 5 groups elder generations of alcohol extract (branch is fried in shallow oil) rate compare with normal group, show significant anoxia tolerance function (P＜0.05), and its effect is better than other 5 groups; And after American Ginseng alcohol extract and dark plum+date alcohol extract use in conjunction, collaborative strengthen (table 1) of effect.
Find that with the method further experiment 3 dosage alcohol extracts (branch is fried in shallow oil) show good dose-effect relationship, its function is strengthened with dosage, sees Table 2.
Two, improve memory function (darkness avoidance test)
The ICR mouse is divided into 7 groups at random: normal group, model group, piracetam group, water extract (close and fry in shallow oil) group, water extract (branch is fried in shallow oil) group, alcohol extract (close and fry in shallow oil) group, alcohol extract (branch is fried in shallow oil) group, American Ginseng alcohol extract group, dark plum+date alcohol extract group.
Per os gives respectively to be tried thing 5d continuously, d4 model group in the morning with tried thing group ip hyoscine 2.0mg/kg, capacity physiological saline such as normal group ip are kept away dark training with the passive avoidance reflectometer behind the 20min, parameter is square wave stimulation: ripple is wide: 125ms; Amplitude: 40V.PP measures mouse and enters errors number in the 5min of darkroom from bright chamber under the quiet environment behind the 24h, weigh learning and memory abilities in aging mice with errors number.
The different extracts of table 3 to amnemonic improvement effect due to the hyoscine (x ± s, n=8)
Compare with normal group #P＜0.05;
*Compare with model group P＜0.05
By table 3 as seen, Scop moulding group passive avoidance errors number and normal control group are than significantly increasing (P＜0.05), and memory disorders appear in the hints model group; To memory disorders due to the hyoscine, errors number all obviously reduces (P＜0.05) in joining plum extract group and model group being compared 5min, wherein, the strongest with alcohol extract (branch is fried in shallow oil) group with the effect of American Ginseng alcohol extract group, and after American Ginseng alcohol extract and dark plum+date alcohol extract use in conjunction, collaborative strengthen (table 3) of effect.
Above pharmacological testing shows that functional food of the present invention has anoxia tolerance function and improves memory function, and prescription rationally.Therefore claim the energy particle again.
The specific embodiment
Embodiment 1
Get 1 part of 1 part of American Ginseng, dark plum and 2 parts in date, extract 3 times with 5 times of amount 70% alcohol heating reflux respectively, each 0.5 hour, filter, the difference merging filtrate, be evaporated to an amount of spray-dried separately and become fine powder, merge two kinds of fine powders, mixing, add and fine powder equivalent auxiliary material, wherein sucrose 10%, lactose 20%, microcrystalline cellulose 15%, starch 25%, silica 1 0%, dolomol 10%, talcum powder 5% and HPC5% granulate the can capsule.
Embodiment 2
Get 3 parts of 2 parts of American Ginsengs, dark plum and 4 parts in date, extract 2 times with 10 times of amount 50% alcohol heating reflux respectively, each 1.0 hours, filter, the difference merging filtrate, be evaporated to an amount of spray-dried separately and become fine powder, merge two kinds of fine powders, mixing, add and 2 times of amounts of fine powder auxiliary material, wherein sucrose 10%, PVP 20%, methylcellulose 15%, starch 25%, silica 1 0%, hydrogenated vegetable oil 10%, talcum powder 5% and CMC-Na 5% are granulated the can capsule.
Embodiment 3
Get 3 parts of 6 parts of American Ginsengs, dark plum and 2 parts in date, extract 2 times with 15 times of amount 30% alcohol heating reflux respectively, each 1.5 hours, filter, the difference merging filtrate, be evaporated to an amount of spray-dried separately and become fine powder, merge two kinds of fine powders, mixing, add and 1 times of amount of fine powder auxiliary material, wherein sucrose 10%, PVP 20%, methylcellulose 15%, starch 25%, silica 1 0%, hydrogenated vegetable oil 10%, talcum powder 5% and CMC-Na 5% are granulated compressing tablet.
Embodiment 4
Get 3 parts of 6 parts of American Ginsengs, dark plum and 2 parts in date, use 15 times of water gaging heating and refluxing extraction 3 times respectively, each 0.5 hour, filter, the difference merging filtrate, be evaporated to an amount of spray-dried separately and become fine powder, merge two kinds of fine powders, mixing, add and 1 times of amount of fine powder auxiliary material, wherein lactose 20%, dextrin 10%, HPMC 15%, dried starch 25%, silica 1 0%, superfine silica gel powder 10%, talcum powder 5% and PEG4000 5% are granulated compressing tablet.
Claims (8)
1, a kind of health food is characterized in that being concentrated by following raw materials according and ratio of weight and number water or ethanol heating extraction, is drying to obtain: 3～6 parts of American Ginsengs, 3～10 parts of dark plums, 2～20 parts in date.
2, a kind of health food is characterized in that being concentrated by following raw materials according and ratio of weight and number water or ethanol heating extraction, is drying to obtain: 2～3 parts of American Ginsengs, 2～3 parts of dark plums, 4～6 parts in date.
3, a kind of health food is characterized in that being concentrated by raw material and ratio of weight and number water or ethanol heating extraction, is drying to obtain: 1 part of American Ginseng, 1 part of dark plum, 2 parts in date.
4, claim 1,2 or 3 described health foods is characterized in that: American Ginseng is heated extraction, concentrated, dry separately, and again that the extract of dark plum and date is concentrated, dry, merge dry thing promptly.
5, claim 1,2 or 3 described health foods is characterized in that: with American Ginseng alcohol extract, concentrated, dry, dark plum and date remerge promptly with alcohol extract, concentrated, dry.
6, the described health food of claim 5, wherein concentration of ethanol is 30～95%.
7, claim 1,2 or 3 described health foods also are included in the extract obtained middle auxiliary material that adds and are prepared into various formulations.
8, the described health food of claim 7, formulation is oral liquid, capsule or tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB200610097230XA CN100425159C (en) | 2006-10-25 | 2006-10-25 | Health food and its preparing method |
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| Application Number | Priority Date | Filing Date | Title |
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| CNB200610097230XA CN100425159C (en) | 2006-10-25 | 2006-10-25 | Health food and its preparing method |
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| Publication Number | Publication Date |
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| CN1943419A CN1943419A (en) | 2007-04-11 |
| CN100425159C true CN100425159C (en) | 2008-10-15 |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101253989B (en) * | 2008-04-07 | 2011-07-27 | 北京惠中铭捷生物科技有限公司 | Health food with improving anoxia tolerant function and its preparation |
| CN102657716A (en) * | 2012-06-04 | 2012-09-12 | 通化爱心药业有限责任公司 | Anti-aging traditional Chinese medicine composition and preparation method thereof |
| CN103564300B (en) * | 2013-11-22 | 2015-04-08 | 威海环翠楼红参科技有限公司 | Processing process of Korean red ginseng honey slices |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1200937A (en) * | 1998-05-04 | 1998-12-09 | 刘振华 | Soboring-up liver-protecting medicine and preparation method therefor |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1200937A (en) * | 1998-05-04 | 1998-12-09 | 刘振华 | Soboring-up liver-protecting medicine and preparation method therefor |
Non-Patent Citations (2)
| Title |
|---|
| 西洋参药理作用研究的最新进展. 王筠默.人参研究，第13卷第4期. 2003 |
| 西洋参药理作用研究的最新进展. 王筠默.人参研究，第13卷第4期. 2003 * |
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| CN1943419A (en) | 2007-04-11 |
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Granted publication date: 20081015 Termination date: 20111025 |