CN100396301C - Blood-nourishing oral liquid with nine ingredients - Google Patents
Blood-nourishing oral liquid with nine ingredients Download PDFInfo
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Abstract
The present invention discloses a blood-nourishing oral liquid with nine ingredients, which is made from nine traditional Chinese medicines such as ginseng, milk vetch, gynostemma pentaphylla, etc. Compared with the simple blood-nourishing medicine, the oral liquid which is essential progress has the advantages that the self hemopoietic function of a human body is improved by improving the endocrine and the metabolism function of the human body, both qi and blood are nourished, and the anemia is roundly treated. The blood-nourishing oral liquid with nine ingredients has the effects of supplementing qi, nourishing blood, strengthening the spleen and benefiting the stomach, is suitable for treating disease symptoms such as insomnia and amnesia of deficiency of both qi and blood, palmus severe palpitation, light headedness, loss of vitality, lack of strength, shortness of breath, spontaneous perspiration, anorexia, etc. The disease resistance of the human body can be improved, and the aging can be delayed if a person usually drinks the blood-nourishing oral liquid with nine ingredients.
Description
Technical field
The present invention relates to a kind of medicine, the Chinese medicine of especially enriching blood.
Background technology
1, the harm of anemia:
Anemia is meant that hemoglobin (Hb) amount in the blood is lower than the value with age and healthy subjects of same sex, Hb＜120g/L of adult man, and Hb＜110g/L of adult woman it is generally acknowledged to have anemia.
Anemia is a series of common reveal any symptoms that many different reasons or disease cause, rather than a kind of title of disease.Common clinically have iron deficiency anemia, aplastic anemia, hemolytic anemia, hemorrhagic anemia and a megaloblastic anemia.Also have the anemias that all can occur together such as chronic inflammatory disease, infection, uremia, hepatopathy, connective tissue disease, malignant tumor, endocrinopathy in addition.The hemoglobin reduction of suffering from the anemia descendant, blood oxygen carrying capacity lowers, body tissue and organ generation anoxia.The weight that has that it's too late of Anemia except that primary disease character, more depends primarily on severity of anemia and development speed thereof, also with patient age, have or not the compensatory capacity of heart disease and cardiovascular system relevant.That the common performance of anemia has is tired, weak, dizzy, dim eyesight, tinnitus, hypomnesis, absent minded etc., and palor, lusterless complexion are the modal objective signs of anemia.But judge that only according to skin color anemia often has error, generally judge comparatively reliable with the nail matrix color of eye conjunctiva, lip mucosa and fingernail.But anemia patient also had palpitation, heart rate accelerate, movable back tachypnea, inappetence, feel sick, phenomenon such as abdominal distention, edema, low grade fever, albuminuria can take place in severe patient, amenorrhea and sexual hypofunction etc. are bigger to health hazard.
2, the market of hematonic:
According to World Health Organization (WHO) statistics, the whole world has 3,000,000,000 people that in various degree anemia is arranged, and annually causes that because of suffering from anemia the dead number of all kinds of diseases is up to ten million.The population probability of middle national trouble anemia is higher than western countries, and in the crowd who suffers from anemia, the women is apparently higher than the male, and the old man child is higher than the young and the middle aged.There is 30%～40% infant to suffer from anemia approximately, mainly be because the chain reaction that the parent anemia causes, cause the underfeed of the haematopoietic substance that neonate absorbs from parent, physique and intelligence development are had a strong impact on, produce anorexia, particular about food, various infection resistances are gone down etc.Women's anemia sickness rate is 64.4%, women's official holiday, when conceived self and fetus to the dual requirements of haematopoietic substance, childbirth is hemorrhage all is immediate cause.The main cause of past anemia is a malnutrition, in recent years because of fat-reducing causes nutritional disorder, has formed the another big crowd of anemia.The number of China's anemia is about 600,000,000 people.Therefore, hematonic has very big market prospect.
3, the Chinese medicine advantage of enriching blood:
The title that does not have anemia in the Chinese medicine, but from the clinical syndrome performance that presents of patient, as tired unable, the cardiopalmus of pale complexion, body, breathe hard, dizzy, lassitude, arteries and veins see thin and delicate etc., then similar in appearance to " blood deficiency ", " deficiency of YIN " all diseases.Generally anemia can be put under the category of the traditional Chinese medical science " blood deficiency " and " asthenia exhaustion of blood ".
Blood is that the effect of water paddy process gas is transformed, and its generation and the heart, spleen, stomach, kidney have confidential relation.Heart master blood, blood stored in the liver, The spleen governs the blood.Blood and gas in close relations, not only the generation of blood is relevant with gas, and the operation of blood also needs the promotion by gas.Therefore, the deficiency of vital energy usually can cause blood deficiency, and blood deficiency also has the deficiency of vital energy to exist simultaneously, will take into account QI invigorating when enriching blood.Traditional Chinese medical science blood deficiency comprises diseases such as the anemia, neurosis, some weak disease, menoxenia of modern medicine, can show as lustreless complexion or sallow, palpitation and dizziness, unable, the body of breathing hard empty weak, the fingernail color is light, menoxenia, insomnia and dreamful sleep, postmenstrual abdominal pain, thready pulse pale tongue etc.The treatment anemia is " what lacks what is mended " mostly at present, is a kind of passive directly replenishing, and this can improve some Anemias in a short time, but can not tackle the problem at its root.
Summary of the invention
The purpose of this invention is to provide a kind ofly, can improve the blood-nourishing oral liquid with nine ingredients of self hemopoietic function by improving human organism's E﹠M.
The invention is characterized in that this medicine is prepared from by the raw material of Chinese medicine of following composition by weight:
70～130 parts of 70～130 portions of Herb Gynostemmae Pentaphylli of 50～100 parts of Radixs Astragali of Radix Ginseng
35～65 parts of 50～100 parts of Rhizoma Atractylodis Macrocephalaes of 70～130 parts of Radix Angelicae Sinensis of Fructus Schisandrae Chinensis
20～50 parts in 35～65 portions of Radix Glycyrrhizaes of 20～50 portions of Fructus Crataegis of Pericarpium Citri Reticulatae.
Method for making:
Get Radix Ginseng, Herb Gynostemmae Pentaphylli, Fructus Schisandrae Chinensis, Pericarpium Citri Reticulatae, Radix Angelicae Sinensis powder by weight and be broken into coarse powder, mixing, according to the percolation under fluid extract and the extractum item (appendix IO of Chinese Pharmacopoeia version in 2000), make solvent with 65% ethanol, flood after 24 hours,, collect the liquid of filtering with the speed of per minute 3ml percolation slowly, reclaim ethanol, being concentrated into relative density is the clear paste of 1.12～1.20 (80 ℃).Medicinal residues and all the other Radixs Astragali, the Rhizoma Atractylodis Macrocephalae, Fructus Crataegi and Radix Glycyrrhizae four are distinguished the flavor of, and add the water of 10 times of amounts, decoct secondary, and 2 hours for the first time, 1.5 hours for the second time.Merge decocting liquid twice, leave standstill, filter, filtrate is concentrated into the clear paste that relative density is 1.12～1.20 (80 ℃), adds ethanol and makes that to contain the alcohol amount be 70%, stir evenly, left standstill 24 hours, and got supernatant and reclaim ethanol, add the concentrated solution of the five tastes such as above-mentioned Radix Ginseng, being concentrated into relative density is the clear paste of 1.12～1.20 (80 ℃), regulate pH value to 6.5 with 40% sodium hydroxide solution, left standstill 24 hours, filter, filtrate adds the sucrose of 250～350 weight portions and the antiseptic of 0.3～0.8 weight portion, add 1～1.5 times in water, stir evenly fill, sterilization promptly gets oral liquid.
In addition, also can make cream, ball and tablet and capsule etc. by material component of the present invention by the method for routine.
Blood-nourishing oral liquid with nine ingredients of the present invention is not some composition in the direct supplemental blood to the treatment of enriching blood, but endocrine and metabolic function by improving the human organism, improve self hemopoietic function, reach qi and blood tonifying, treat anemia comprehensively, this compares with general simple hematonic, is the progress of an essence.This Chinese medicine has the effect of vigorate qi and replenish the blood, invigorating spleen and reinforcing stomach.Be used for QI and blood deficiency insomnia forgetfulness, severe palpitation, have a dizzy spell, the treatment of disease such as spiritlessness and weakness, the spontaneous perspiration of losing heart, indigestion and loss of appetite lack of appetite.Often take and to improve human organism's resistance against diseases, slow down aging.But also be that following advantage is arranged:
1, economical and practical, promote easily: this medicine raw material resources is abundant, production technology advanced person, and manufacturing cost is lower.
2, scientific and reasonable, effect is remarkable: this product is according to the interpromoting relation in five elements of traditional Chinese medical science QI and blood, and gas is the teacher of blood, and the capable then blood of gas is capable; Blood being the material foundation of QI, blood to gas also to scheduling theory; From hemopoietic function improvement in essence, through to Chinese medicine science compatibility, and adopt modern technologies to refine to form.This technological element of a product height, the effect of enriching blood is remarkable, and total effective rate reaches 91%, welcome by the ward mate.
3, pure tcm product, have no side effect: this product belongs to natural Chinese medicine, and green beverage does not contain poisonous harmful substance, and is safe and reliable, has no side effect.Be fit to the requirement of different growth age groups, comply with mankind's trend that goes back to nature.
The specific embodiment
Embodiment:
The weight portion of getting each raw material of Chinese medicine is:
100 parts of 100 portions of Herb Gynostemmae Pentaphylli of 75 parts of Radixs Astragali of Radix Ginseng
50 parts of 75 parts of Rhizoma Atractylodis Macrocephalaes of 100 parts of Radix Angelicae Sinensis of Fructus Schisandrae Chinensis
30 parts in 50 portions of Radix Glycyrrhizaes of 30 portions of Fructus Crataegis of Pericarpium Citri Reticulatae
According to above-mentioned composition and weight portion, get 75 parts of Radix Ginsengs, 100 parts of Herb Gynostemmae Pentaphylli, 100 parts of Fructus Schisandrae Chinensis, 30 parts of Pericarpium Citri Reticulataes, Radix Angelicae Sinensis and respectively be ground into coarse powder for 75 parts, mixing is mixed thoroughly, according to the percolation under fluid extract and the extractum item (seeing appendix IO of Chinese Pharmacopoeia version in 2000), alcohol solvent with 65% flooded after 24 hours, with the speed of per minute 3ml percolation slowly, the collection liquid 3040ml that filters reclaims ethanol and is concentrated into the clear paste that density is 1.12～1.20 (80 ℃); 100 parts of medicinal residues and all the other Radixs Astragali, 50 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts in Radix Glycyrrhizae add the water of 10 times of amounts, decoct twice, 2 hours for the first time, 1.5 hours for the second time, merge two decocting liquids, left standstill 24 hours, filter, filtrate is concentrated into the clear paste that relative density is 1.12～1.20 (80 ℃), adds ethanol and makes that to contain alcohol amount be 70%, stirs evenly, left standstill 24 hours, and got clear liquid medicine and reclaim ethanol.Add above-mentioned Radix Ginseng, Herb Gynostemmae Pentaphylli, Fructus Schisandrae Chinensis, Pericarpium Citri Reticulatae and Radix Angelicae Sinensis and make clear paste in last clear liquid medicine, mix thoroughly, being concentrated into relative density is 1.10～1.20 (80 ℃), regulate pH value to 6.5 with 40% sodium hydroxide solution, left standstill 24 hours, and filtered, filtrate adds sucrose 300g, ethyl hydroxybenzoate 0.5g, be added to 1000ml, stir evenly, sterilization, fill promptly gets oral liquid.
Using method, each 10ml, every day 3 times, logotype 15 days.
This blood-nourishing oral liquid with nine ingredients is to establish for QI and blood deficiency person.Qi-blood deficiency syndrome is to cause the decline of internal organs QI and blood biochemical function after factor body innate deficiency or serious disease, the prolonged illness, especially in burnt taste source deficiency, cause the deficiency of vital energy to involve blood deficiency, or blood deficiency causes the deficiency of vital energy, thereby qi-blood deficiency syndrome occurs.Insufficiency of vital energy and blood is difficult the flourish head, and brain is become homeless foster, thus see and have a dizzy spell, spiritlessness and weakness, lustreless complexion, insufficiency of vital energy and blood, heart spleen loses empty; Blood failing to tonify the heart is then seen severe palpitation, the diseases such as spontaneous perspiration, insomnia forgetfulness, indigestion and loss of appetite lack of appetite of losing heart.Controlling of assertive evidence is when being the rule of treatment with the invigorating qi and benefiting blood.
Radix Ginseng in raw material is formed, strongly invigorating primordial QI, invigorating spleen and reinforcing stomach, mind tranquilizing and the heart calming, Radix Astragali replenishing QI to invigorate the spleen, the same usefulness of ginseng stilbene, the power of its air making-up and spleen enlivening is stronger, and the energy QI invigorating is with hemopoietic.Gai Yin " tangible blood is born in invisible gas ", " the prosperous blood of gas is spontaneous ", this also " Yin grows while yang is generating " justice also.So monarch drug in ginseng, the stilbene side of being.
The traditional Chinese medical science thinks that " The spleen and stomach provide the material basis of the acquired, source of generating QI and blood." in the event side again with the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae and Radix Ginseng (being to be the Yigong San powder with marveous Effect sanction), it has the merit of invigorating the spleen and benefiting QI, stomach function regulating.The strong fortune of spleen, then source of generating QI and blood abundance.So above each medicine can be strengthened the merit of monarch drug ginseng stilbene invigorating qi and benefiting blood, is to be the ministerial drug in the side.The benefiting blood and regulating blood circulation of Radix Angelicae Sinensis in the side; The Fructus Schisandrae Chinensis supplementing QI for promoting the production of body fluid; Herb Gynostemmae Pentaphylli is rich in Herb Gynostemmae Pentaphylli Saponin and ginsenoside, and clinical practice has the function of similar Radix Ginseng, so the merit of supplementing QI for promoting the production of body fluid is arranged.Each medicine is shared, all can strengthen the merit of monarch drug vigorate qi and replenish the blood, also the ministerial drug in the side of being all.
Fructus Crataegi in the side, sour sweet tepor has promoting digestion and invigorating the stomach, and the merit of circulation of qi promoting dissipating blood stasis is to be adjuvant drug in the side.
Sweet flat, the coordinating the actions of various ingredients in a prescription of Radix Glycyrrhizae is to be the messenger drug in the side.
More than all medicines share, play vigorate qi and replenish the blood altogether, the merit of invigorating spleen and reinforcing stomach.The insomnia forgetfulness that is used for QI and blood deficiency, severe palpitation is had a dizzy spell, spiritlessness and weakness, the spontaneous perspiration of losing heart, the treatment of diseases such as indigestion and loss of appetite lack of appetite.Informal dress can improve resistance against diseases, the slow down aging of body.
Herb Gynostemmae Pentaphylli is the dry herb of cucurbitaceous plant Herb Gynostemmae Pentaphylli in the prescription, and its quality should meet the requirement of the relevant Herb Gynostemmae Pentaphylli quality standard of country.All the other each flavour of a drug all record in one one of Chinese Pharmacopoeia version in 2000, and adjuvant sucrose should meet the regulation of two ones of Chinese Pharmacopoeia versions in 2000.
This blood-nourishing oral liquid with nine ingredients has been done clinical observation on the therapeutic effect in first Affiliated Hospital of Colleges Of Traditional Chinese Medicine Of Guangxi, second Affiliated Hospital of Colleges Of Traditional Chinese Medicine Of Guangxi and The People's Hospital, Guangxi Zhuang Autonomous Region, and conclusion is:
1, blood-nourishing oral liquid with nine ingredients is the new product of Chinese medicine of Chinese medicine expert according to the clinical experience development, through observing this oral liquid qi-blood deficiency syndrome is had therapeutical effect preferably.Treatment back patient's insomnia and dreamful sleep takes a turn for the better, and symptoms such as spiritlessness and weakness, deficiency of QI with disinclination to talk, dizziness and blurred vision, spontaneous perspiration, severe palpitation, indigestion and loss of appetite lack of appetite all have clear improvement, and the prompting blood-nourishing oral liquid with nine ingredients has vigorate qi and replenish the blood, the effect of invigorating spleen and reinforcing stomach.
2, this organizes 120 examples, contrasts 60 examples, and treatment back peripheral blood Hb content obviously increases, and the prompting blood-nourishing oral liquid with nine ingredients can improve Hb content in the blood of human body.
3, this organizes 120 examples, total effective rate 91.7%.Matched group 60 examples, total effective rate are 93.3%.Two groups of curative effects are no significant differences relatively, and the prompting blood-nourishing oral liquid with nine ingredients treatment vim and vigour two void curative effect of being insomnia is consistent with one Hundred Years Oral Liquid.
4, this product is safe and reliable, no obvious adverse reaction and toxic and side effects.
Model case:
Example 1 Deng, women, 31 years old.The dizzy insomnia of excuse showed effect 2 years repeatedly, went to a doctor on November 5th, 1994.Disease is seen: insomnia is outbreak repeatedly, difficulty falling asleep or sleeping be dream, lie awake all night in the time of very.With dim eyesight, spiritlessness and weakness, dizziness, deficiency of QI with disinclination to talk, severe palpitation, anorexia, be difficult to adhere to routine work.Check: BP9/6kpa, lusterless complexion, pale tongue, tongue fur is white, thready pulse without strength.Routine blood test: Hb103g/L, RBC3.4 * 10
12/ L, WBC4.1 * 10
9/ L.Tcm diagnosis: be insomnia (QI and blood deficiency).Western medicine diagnose: hypotension.Give the blood-nourishing oral liquid with nine ingredients treatment, each 10ml, every day 3 times.After taking medicine 5 days, can sleep every night 2～3 hours, diseases such as dizziness and blurred vision alleviate.Sleep and other symptom shapes are clearly better after 10 days.Insomnia and dreamful sleep disappears after 15 days, and food is received normal.Check BP12/9Kpa.Routine blood test: Hb123g/L, WBC4.4 * 10
9/ L.Efficacy evaluation: clinical recovery.
Example 2 Wus, women, 52 years old.Because of insomnia and dreamful sleep spiritlessness and weakness half a year, go to a doctor on November 9th, 1994.After the most of excision of readme stomach 1 year, nearly half a year normal insomnia and dreamful sleep, the easy tired power of refreshment.With dizziness and blurred vision, deficiency of QI with disinclination to talk, spontaneous perspiration, indigestion and loss of appetite.Check: shape is not become thin, pale complexion is simple and unadorned, light red tongue, thready and weak pulse.Routine blood test: Hb86g/L, RBC2.9 * 10
12/ L, WBC4.4 * 10
9/ L.Tcm diagnosis: be insomnia (deficiency of both QI and blood).Western medicine diagnose: stomach is cut postoperative, anemia greatly.Give the blood-nourishing oral liquid with nine ingredients treatment, each 10ml, every day 3 times.Sleep takes a turn for the better after 5 days, can fall asleep every night 1～2 hour, can fall asleep every night more than 4 hours after 10 days, and other symptoms are clearly better.Sleep and food are received normally after 15 days, other transference cures, weight increase 1kg.Routine blood test: Hb112g/L, RBC4.1 * 10
12/ L, WBC4.8 * 10
9/ L.Efficacy evaluation: clinical recovery.
Claims (2)
1. blood-nourishing oral liquid with nine ingredients is characterized in that this medicine is formed by following parts by weight of Chinese traditional medicine feedstock production:
70～130 parts of 70～130 portions of Herb Gynostemmae Pentaphylli of 50～100 parts of Radixs Astragali of Radix Ginseng
35～65 parts of 50～100 parts of Rhizoma Atractylodis Macrocephalaes of 70～130 parts of Radix Angelicae Sinensis of Fructus Schisandrae Chinensis
20～50 parts in 35～65 portions of Radix Glycyrrhizaes of 20～50 portions of Fructus Crataegis of Pericarpium Citri Reticulatae.
2. blood-nourishing oral liquid with nine ingredients according to claim 1 is characterized in that this medicine is formed by following parts by weight of Chinese traditional medicine feedstock production:
100 parts of 100 portions of Herb Gynostemmae Pentaphylli of 75 parts of Radixs Astragali of Radix Ginseng
50 parts of 75 parts of Rhizoma Atractylodis Macrocephalaes of 100 parts of Radix Angelicae Sinensis of Fructus Schisandrae Chinensis
30 parts in 50 portions of Radix Glycyrrhizaes of 30 portions of Fructus Crataegis of Pericarpium Citri Reticulatae.
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| CN103494934B (en) * | 2013-10-15 | 2015-08-26 | 广西盈康药业有限责任公司 | A kind of Sugarless type blood-nourishing oral liquid with nine ingredients and preparation method thereof |
| CN105166235A (en) * | 2015-09-28 | 2015-12-23 | 李修田 | Qi-blood tonifying health tea capable of reducing hyperlipidemia, hypertension and hyperglycemia and preparation method thereof |
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| Title |
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| 中医药治疗再生障碍性贫血研究进展. 李建平等.湖南中医药导报，第10卷第3期. 2004 |
| 中医药治疗再生障碍性贫血研究进展. 李建平等.湖南中医药导报，第10卷第3期. 2004 * |
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