CN100378093C - 一种制备包括无定形艾美拉唑及其盐在内的光学纯或光学浓缩的亚砜化合物的方法 - Google Patents

一种制备包括无定形艾美拉唑及其盐在内的光学纯或光学浓缩的亚砜化合物的方法 Download PDF

Info

Publication number
CN100378093C
CN100378093C CNB038151529A CN03815152A CN100378093C CN 100378093 C CN100378093 C CN 100378093C CN B038151529 A CNB038151529 A CN B038151529A CN 03815152 A CN03815152 A CN 03815152A CN 100378093 C CN100378093 C CN 100378093C
Authority
CN
China
Prior art keywords
salt
omeprazole
alkyl
sulfoxide
adducts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB038151529A
Other languages
English (en)
Chinese (zh)
Other versions
CN1665805A (zh
Inventor
M·S·雷迪
M·K·库玛
K·S·雷迪
K·普兰德哈尔
K·斯雷内司
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr Reddys Research Foundation
Dr Reddys Laboratories Inc
Original Assignee
Dr Reddys Research Foundation
Dr Reddys Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Reddys Research Foundation, Dr Reddys Laboratories Inc filed Critical Dr Reddys Research Foundation
Publication of CN1665805A publication Critical patent/CN1665805A/zh
Application granted granted Critical
Publication of CN100378093C publication Critical patent/CN100378093C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

CNB038151529A 2002-06-27 2003-06-27 一种制备包括无定形艾美拉唑及其盐在内的光学纯或光学浓缩的亚砜化合物的方法 Expired - Fee Related CN100378093C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN489MA2002 2002-06-27
IN489/MAS/2002 2002-06-27
IN493MA2002 2002-06-28
IN493/MAS/2002 2002-06-28

Publications (2)

Publication Number Publication Date
CN1665805A CN1665805A (zh) 2005-09-07
CN100378093C true CN100378093C (zh) 2008-04-02

Family

ID=34276871

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB038151529A Expired - Fee Related CN100378093C (zh) 2002-06-27 2003-06-27 一种制备包括无定形艾美拉唑及其盐在内的光学纯或光学浓缩的亚砜化合物的方法

Country Status (5)

Country Link
CN (1) CN100378093C (de)
AT (1) ATE353887T1 (de)
AU (1) AU2003247729B2 (de)
CA (1) CA2491118A1 (de)
DE (1) DE60311809T2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2143722A1 (de) * 2008-07-09 2010-01-13 Lek Pharmaceuticals D.D. Verfahren zur Herstellung von Esomeprazol-Natrium von hoher chemischer Reinheit und neue Formen von Esomeprazol-Natrium
CN103145694B (zh) * 2011-12-06 2016-01-20 重庆煜澍丰医药有限公司 埃索美拉唑钠盐的晶体r及其制备方法和用途
CN102993184A (zh) * 2013-01-08 2013-03-27 湖南方盛制药股份有限公司 一种埃索美拉唑及其镁盐三水合物的制备方法
CN103664887B (zh) * 2013-12-18 2015-09-16 成都医路康医学技术服务有限公司 埃索美拉唑钠的制备方法
CN104530003A (zh) * 2014-06-10 2015-04-22 广东东阳光药业有限公司 吡啶甲基亚磺酰基-1h-苯并咪唑类化合物的盐的制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998028294A1 (en) * 1996-12-20 1998-07-02 Astra Aktiebolag A novel compound form
WO1998054171A1 (en) * 1997-05-30 1998-12-03 Astra Aktiebolag Novel form of s-omeprazole
US6369087B1 (en) * 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998028294A1 (en) * 1996-12-20 1998-07-02 Astra Aktiebolag A novel compound form
WO1998054171A1 (en) * 1997-05-30 1998-12-03 Astra Aktiebolag Novel form of s-omeprazole
US6369087B1 (en) * 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Kinetic Resolution of Sulfoxides Catalyzed by ChiralTitanium-Binaphthol Complex. KOMATSU N. ET AL.JOURNAL OF ORGANIC CHEMISTRY,Vol.58 . 1993 *

Also Published As

Publication number Publication date
DE60311809D1 (de) 2007-03-29
CA2491118A1 (en) 2004-01-08
ATE353887T1 (de) 2007-03-15
AU2003247729A1 (en) 2004-01-19
DE60311809T2 (de) 2007-11-22
CN1665805A (zh) 2005-09-07
AU2003247729B2 (en) 2009-10-08

Similar Documents

Publication Publication Date Title
EP1515963B1 (de) Verfahren zur herstellung optisch reiner oder optisch angereicherter sulfoxidverbindungen einschliesslich amorphen esomeprazols und dessen salze
RU2184734C2 (ru) S-омепразол в нейтральной форме, способы его получения, фармацевтическая композиция, содержащая s-омепразол в нейтральной форме, и способ лечения связанного с желудочной кислотой состояния
KR101035534B1 (ko) 결정의 제조방법
KR101062806B1 (ko) 광학적으로 순수한 활성 화합물의 제조 방법
RU2345075C2 (ru) Способ получения фармацевтических средств и соединения, полученные данным способом
JP2012246316A (ja) エソメプラゾールのナトリウム塩の製造に使用するための結晶の改変型の作成方法
DE60114028T2 (de) Verfahren zur herstellung von wasserfreiem azithromycin
CN100378093C (zh) 一种制备包括无定形艾美拉唑及其盐在内的光学纯或光学浓缩的亚砜化合物的方法
KR101169471B1 (ko) (ｓ)-판토프라졸의 제조 방법
CN109071486A (zh) 用于治疗感染的组合物和方法
AU2008346115A1 (en) A process for preparation of stable amorphous R-lansoprazole
JP2002529497A5 (de)
AU2002344386B2 (en) S-omeprazole (esomeprazole) inclusion complex with cyclodextrins
KR100869677B1 (ko) 결정의 제조방법
JP2002037783A (ja) 結晶の製造法
JP2002338567A (ja) 結晶の製造法
HRP980251A2 (en) New form of a compound
KR20070023757A (ko) 에소메프라졸 나트륨염의 제조에서 사용하기 위한 결정변형의 제조를 위한 신규한 방법

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20080402