CN100358488C - Whitening crystal invisual face film for activating skin and production thereof - Google Patents

Whitening crystal invisual face film for activating skin and production thereof Download PDF

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Publication number
CN100358488C
CN100358488C CNB2005100401474A CN200510040147A CN100358488C CN 100358488 C CN100358488 C CN 100358488C CN B2005100401474 A CNB2005100401474 A CN B2005100401474A CN 200510040147 A CN200510040147 A CN 200510040147A CN 100358488 C CN100358488 C CN 100358488C
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China
Prior art keywords
citrullus vulgaris
skin
invisual
crystal
agent
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Expired - Fee Related
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CNB2005100401474A
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Chinese (zh)
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CN1711987A (en
Inventor
陆泽俭
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HUAXIA KEEP IN GOOD HEALTH ACADEMIC INST ANHUI
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HUAXIA KEEP IN GOOD HEALTH ACADEMIC INST ANHUI
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Abstract

The present invention relates to a crystalline transparent skin activation masque used for skin beautification and making up, which comprises the components of the following percentage: 0.01 to 10% of watermelon essence, 70 to 95% of bioadhesion gelatin and 4.99 to 20% of adjunctive preparation or adjunctive material, wherein the watermelon essence refers to the watermelon bioconcentrated elements of potassium (guafujia for short), citrulline, watermelon polysaccharide, watermelon pectin, etc., and the guafujia and the citrulline exist by coordinating with each other to form potassium citrulline. The present invention can activate skin cells, regulate Ca<2+> in cells, soften keratinized epidermal cells to make skin fine and tender again, prevent skin from senescence and roughening, eliminate brown pigment and metabolin depositing on epidermal cells, make the skin color of the face, neck, upper and lower limbs and other uncovered parts immediately become white and tender in 2 to 5 minutes after application.

Description

Whitening crystal invisual face film for activating skin and preparation method thereof
Technical field
The present invention relates to a kind of cosmetics, specifically is exactly whitening crystal invisual face film for activating skin.
Background technology
Loving beauty is part of human nature, and the cosmetics that are used for skin-whitening have become the product of Mrs fashion indispensability, and wherein " facial film " is one of cosmetics commonly used.Up to now, the preparation of facial film and type of service thereof are generally: stick melon and fruit slice, coating natural plants, animal, mineral dust paste or extractum in face portion, be coated with the Plastering facial film and paste papery or with mask formula facial film of macromolecular material preparation or the like.Generally all exist trivial operations, the time spent is longer, and is very inconvenient, and needs to be beauty treatment person more and lie on the Beauty bed, by professional cosmetologist's operation.In addition, when seeing its face suddenly under the third party is not having the situation of mental preparation, being everlasting produces feeling of terror mentally or detests sense.
The invention of whitening crystal invisual face film for activating skin and application are taken on a new look beauty mask.
Summary of the invention
The purpose of this invention is to provide a kind of whitening crystal invisual face film for activating skin, the paste of this water white crystal glass sample is coated on the face, the facial film that forms is cryptomorphic, thereby others does not see that beauty treatment person is using facial film, beauty treatment person when doing the facial film cosmetology, amusement and recreation simultaneously, or be engaged in work, the reception kith and kin are visiting, manage one's household etc.The active substance of this product can be by skin absorbs, and its carrier matrix can be simulated the skin lipid protective layer and be formed very thin protective filmy layer on skin, help skin protection and preserve moisture, if thereby be coated with and use when a small amount of, also can flush away, use this product very convenient.
Technical scheme of the present invention is as follows:
Whitening crystal invisual face film for activating skin, the rich potassium of melon), citrulline (form that they exist in fact is a potassium and the citrulline potassium of citrulline coordination composition), Citrullus vulgaris polysaccharide, Citrullus vulgaris pectin etc. be the gel that contains the Citrullus vulgaris essence, described Citrullus vulgaris essence is meant in Citrullus vulgaris the Citrullus vulgaris biological concentration element that extracts preparation: potassium (is called for short:.
Described crystal invisual face film comprises following component and weight content: Citrullus vulgaris essence: 0.01~10%; Bioadhesive gel: 70~95%; Additives (or adjuvant) 4.99~20%.
Described bioadhesive gel, make by adhesive agent, pH regulator agent, pure water, adhesive agent is the adhesion material that can be used as medicine-releasing system, comprises natural or synthetic high molecular polymer, and wherein natural polymer has pectin, sodium alginate, arabic gum, gelatin or the like; Synthetic polymer has carbomer, polyvinylpyrrolidone, Polyethylene Glycol or the like; PH regulator agent an amount of triethanolamine commonly used, sodium hydroxide or the like, it is neutral regulating gelinite; Pure water refers to distilled water or deionized water; Described additives are meant penetrating agent: phosphoamide etc., chelating agent and stabilizing agent: EDTA-2Na etc.; Adjuvant refers to: propylene glycol, glycerol etc.
Described crystal invisual face film is characterized in that the weight content ratio of its each component is:
Citrullus vulgaris essence 2.01%
Carbomer 1%
Sodium hydroxide 0.2%
Triethanolamine 0.5%
Propylene glycol 6%
Glycerol 3%
Phosphoamide 5%
EDTA-2Na 0.03%
Distilled water adds to 100%.
Described crystal invisual face film is characterized in that the weight content ratio of its each component is:
Citrullus vulgaris essence 8.02%
Propylene glycol 4%
Glycerol 4%
Phosphoamide 8%
EDTA-2Na 0.04%
PH regulator agent (regulating pH to 7) is an amount of
Distilled water adds to 100%.
The preparation method of described whitening crystal invisual face film for activating skin the present invention includes following steps:
Former, adjuvant pre-treatment;
The preparation of bioadhesive gel agent;
The interpolation of bioactive substance;
The inspection of semifinished product, packing, product inspection, warehouse-in (storage requires and logistics distribution).
Characteristics of the present invention are at first the substrate of bioadhesive gel agent (Bioadhesive Gels) as facial film, thereby make facial film similar water crystal glass sample water white transparency.The bioadhesive gel agent is that a kind of faster new bio of development in recent years adheres to medicine-releasing system, be a kind of semi-solid preparation, except having lasting medicine, use conveniently, can avoiding the characteristic of bioadhesive polymers such as first pass effect, also have characteristics such as good dispersion, adhesion are strong, medicine-feeding part local concentration height, the present invention is by the preferred ingredient prescription, reach the rapid transdermal that promotes bioactive substance and absorb, improve activating skin effect such as whiten.
Main feature of the present invention is that the main active of the bioactive substance that adds in the whitening crystal invisual face film for activating skin is a Citrullus vulgaris essence etc.The rich potassium of melon), the mixture of citrulline (form that they exist in fact is a potassium and the citrulline potassium of citrulline coordination composition), Citrullus vulgaris polysaccharide, Citrullus vulgaris pectin etc. described Citrullus vulgaris essence is the extract of Citrullus vulgaris, is meant in Citrullus vulgaris the Citrullus vulgaris biological concentration element that extracts preparation: potassium (is called for short:.The rich potassium of melon has the intracellular calcium regulating action; Citrulline has special special biological activity, has nourishing, skin-protecting function; And Citrullus vulgaris pectin, Citrullus vulgaris polysaccharide are preserved moisture except that having, the nourishing, skin-protecting function, also be important substrate or its key component of bioadhesive gel agent.
Modern study has confirmed that calcium ion is most important a kind of physiological regulation factor in the body, it not only participates in excitement one contraction coupling of muscle cell, but also activities such as participation neurotransmitter secretion, it has numerous physiological functions as the second message,second messenger in various cells.Forming the inside and outside calcification structure of cell many lower animals (as some heliozooid, porous worm, coral polyp etc.) itself is exactly a stage of cell life process, and the final final result of some pathogenic histiocyte also is calcification usually in human body.As if calcium participate in the overall process of cell activities, existing studies show that free calcium in cell, lack of proper care (gathering) be likely cytopathy or stress the time with the link of general character, and the important pathological physiological significance is arranged, can be referred to as high calcium syndrome or the nervous attitude of calcium in the cell.The people is after growth is reached maturity, because factors such as endocrine, begin to occur the loss of calcium in the osseous tissue, so-called " calcium deficiency " is meant osseous tissue, calcium runs off in osseous tissue, and in the cell of its hetero-organization, assemble unusually, that is: free calcium is lacked of proper care in cell, then causes the cellular stress or the pathological changes of these tissues.Dim Huang appears in skin colour, or produces dim brown pigment, or coarse, desquamation etc., often with the cell of skin histology in free calcium to assemble (imbalance) unusually relevant, cause the cellular stress of skin histology.
Whitening crystal invisual face film for activating skin is that the Citrullus vulgaris biological concentration element potassium (the rich potassium of melon) in the Citrullus vulgaris essence has the intracellular calcium regulating action to the scientific basic of the skin whitening, moisturizing and nourishing function of skin, and the activation Skin Cell is regulated Ca in the cell 2+It is delicate soft that softening epidermal keratinocytes is reproduced skin, prevent skin aging, coarse, dispel heavy dim brown pigment and the metabolism rubbish that gathers at epidermis cell, can make the exposed position colours of skin such as facial appearance and neck position, upper and lower limbs upright existing fair fresh and tender in 2~5 minutes after use.
In addition, in the Citrullus vulgaris essence, also contain magical nutrient substance: citrulline, and Citrullus vulgaris polysaccharide, Citrullus vulgaris pectin etc. with special natural moisture preserving function.Can be by following little experiment, the water holding capacity of preserving moisture of textual criticism Citrullus vulgaris: with the Citrullus vulgaris chopping, spread in the rustless steel tray, put heating, drying in the drying baker, resulting dry solids is less than 10%.After tested: contain 95~97% moisture in the Citrullus vulgaris approximately, this shows, can keep being equivalent to the moisture of the about 10 times of amounts of dry in the Citrullus vulgaris, its material base is except the Citrullus vulgaris polysaccharide with special natural moisture preserving, nourishing, skin-protecting function, Citrullus vulgaris pectin, also because the Citrullus vulgaris biological concentration element potassium in the Citrullus vulgaris, form citrulline potassium with the citrulline coordination, has very powerful moisturizing function, make cell and water generates hydration reaction, make skin fresh and tender soft and moist, wrinkle disappears, and is dynamic.
Heavy metal substances such as this product is not leaded, hydrargyrum, arsenic, safe in utilization having no adverse reaction.
The suitable crowd of whitening crystal invisual face film for activating skin: wish that appearance is whitened and delicate fair Ms, the man of the exposed position (as: the back of the hand, neck position, upper and lower limbs) of health skin.Especially suitablely begin to occur dim Huang when complexion, or when producing dim brown pigment trend, and hands, limbs portion pachylosis darkness, to whiten with this, effect is obvious.
Summary of drawings
Fig. 1 is preparation technology's flow chart of the present invention.
The specific embodiment
The present invention is described in further detail below in conjunction with drawings and Examples.
Embodiment 1
Whitening crystal invisual face film for activating skin provided by the invention, it comprises following component and weight content span: bioactive substance: 0.01~10%; Bioadhesive gel: 70~95%; Additives or adjuvant 4.99~20%.
Bioactive substance of the present invention is the Citrullus vulgaris essence, is biological concentration potassium, citrulline and their ligand thereof that derives from Citrullus vulgaris: citrulline potassium, and Citrullus vulgaris polysaccharide, Citrullus vulgaris pectin.
Described bioadhesive gel makes with adhesive agent, pH regulator agent, pure water.Adhesive agent is the adhesion material that can be used as medicine-releasing system, comprises natural or synthetic high molecular polymer, and wherein natural polymer has pectin, sodium alginate, arabic gum, gelatin or the like; Synthetic polymer has carbomer, polyvinylpyrrolidone, Polyethylene Glycol or the like.PH regulator agent an amount of triethanolamine commonly used, sodium hydroxide or the like, it is neutral regulating gelinite.Pure water refers to distilled water or deionized water.
Described additives or adjuvant, for: penetrating agent (as phosphoamide etc.), chelating agent and stabilizing agent (as EDTA-2Na etc.), adjuvant (as propylene glycol, glycerol etc.) etc.
Above embodiment 1 is described to be the big component and the content range thereof of whitening crystal invisual face film for activating skin.In order to further specify concrete material composition and the content value that whitening crystal invisual face film for activating skin comprises, following embodiment 2,3 provides more specifically example:
Embodiment 2
A kind of whitening crystal invisual face film for activating skin comprises following component and weight content:
Citrullus vulgaris essence 2.01%
Carbomer 1%
Sodium hydroxide 0.2%
Triethanolamine 0.5%
Propylene glycol 6%
Glycerol 3%
Phosphoamide 5%
EDTA-2Na 0.03%
Distilled water adds to 100%
Embodiment 3
A kind of whitening crystal invisual face film for activating skin comprises following component and weight content:
Citrullus vulgaris essence 8.02%
Propylene glycol 4%
Glycerol 4%
Phosphoamide 8%
EDTA-2Na 0.04%
PH regulator agent (regulating pH to 7) is an amount of
Distilled water adds to 100%
Embodiment 4
Below in conjunction with process chart preparation method of the present invention is elaborated.
1. supplementary material pre-treatment
According to the different chemico-physical properties of various supplementary materials and the requirement of quality standard, it is allocated preceding pre-processing just, comprise: quality inspection, the clean processing, purification refine, pregelatinated is handled, and the preset compounding of the special material of part is closed, make it carry out corresponding physics one chemical reaction, with the high-quality that guarantees final finished and stable.
2. the interpolation of the preparation of bioadhesive gel agent and bioactive substance
Natural polymer (as Citrullus vulgaris pectin, Citrullus vulgaris polysaccharide or sodium alginate, arabic gum, gelatin etc.) or synthetic polymer (as carbomer, polyvinylpyrrolidone, Polyethylene Glycol etc.) are added in the pure water, carry out the gelation pretreatment, it is neutral regulating pH; Add bioactive substance (Citrullus vulgaris essence) and penetrating agent (phosphoamide), chelating agent and stabilizing agent (EDTA-2Na), adjuvant (propylene glycol, glycerol) etc. then; Note the sterile working in the preparation process, stirring operation should be slow, avoids high shear force to stir fast.
3. the inspection of semifinished product, packing, product inspection, storage practice
Carry out the inspection of semifinished product according to national standard and enterprises registration standard, the certified products packing is put in storage after the product inspection, promptly.This product is the natural product goods, should put Liang Chu (2~10 ℃) and preserve.

Claims (5)

1, whitening crystal invisual face film for activating skin is the gel that contains the Citrullus vulgaris essence, and wherein each composition weight content is:
Citrullus vulgaris essence: 0.01~10%;
Bioadhesive gel: 70~95%;
Additives or adjuvant 4.99~20%
Described Citrullus vulgaris essence is meant the Citrullus vulgaris biological concentration element that extracts preparation in Citrullus vulgaris, comprises: potassium, citrulline, Citrullus vulgaris polysaccharide, Citrullus vulgaris pectin.
2, according to claims 1 described crystal invisual face film, it is characterized in that described bioadhesive gel, make by adhesive agent, pH regulator agent, pure water, adhesive agent is the adhesion material that can be used as medicine-releasing system, comprise natural or synthetic high molecular polymer, wherein natural polymer has pectin, sodium alginate, arabic gum, gelatin; Synthetic polymer has carbomer, polyvinylpyrrolidone, Polyethylene Glycol; An amount of triethanolamine, sodium hydroxide used in the pH regulator agent always, and it is neutral regulating gelinite; Pure water refers to distilled water or deionized water; Described additives are meant penetrating agent: phosphoamide, chelating agent and stabilizing agent: EDTA-2Na; Adjuvant refers to: propylene glycol, glycerol.
3, whitening crystal invisual face film for activating skin is characterized in that the weight content ratio of its each component is:
Citrullus vulgaris essence 2.01%
Carbomer 1%
Sodium hydroxide 0.2%
Triethanolamine 0.5%
Propylene glycol 6%
Glycerol 3%
Phosphoamide 5%
EDTA-2Na 0.03%
Distilled water adds to 100%.
4, whitening crystal invisual face film for activating skin is characterized in that the weight content ratio of its each component is:
Citrullus vulgaris essence 8.02%
Propylene glycol 4%
Glycerol 4%
Phosphoamide 8%
EDTA-2Na 0.04%
The pH regulator agent, it is an amount of to regulate pH to 7
Distilled water adds to 100%.
5, the preparation method of whitening crystal invisual face film for activating skin according to claim 1 is characterized in that may further comprise the steps:
Former, adjuvant pre-treatment;
The preparation of bioadhesive gel agent;
The interpolation of bioactive substance;
The inspection of semifinished product, packing, product inspection, warehouse-in.
CNB2005100401474A 2005-05-18 2005-05-18 Whitening crystal invisual face film for activating skin and production thereof Expired - Fee Related CN100358488C (en)

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Application Number Priority Date Filing Date Title
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CN100358488C true CN100358488C (en) 2008-01-02

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI637747B (en) * 2017-06-19 2018-10-11 大江生醫股份有限公司 A composition comprising young watermelon fruit extract, young chiapao melon fruit extract or combination thereof having functionality to regulate the gene expression of interleukin-8, nitric oxide synthase 3, endothelin 1, tissue type-plasminogen activa

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102475658A (en) * 2010-11-29 2012-05-30 吴克 Crystal mask
CN106265349A (en) * 2016-09-22 2017-01-04 厦门市香妃美业化妆品有限公司 Stealthy solubility facial film and preparation method thereof and using method
CN108938502A (en) * 2018-09-29 2018-12-07 中北大学 A kind of edible crystal mask and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1410045A (en) * 2001-09-29 2003-04-16 焦柏忠 Cosmetics made of nano natural material
CN1506108A (en) * 2002-12-09 2004-06-23 戚海燕 Composite milk powder capable of being eaten and made into beautifying face mask

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1410045A (en) * 2001-09-29 2003-04-16 焦柏忠 Cosmetics made of nano natural material
CN1506108A (en) * 2002-12-09 2004-06-23 戚海燕 Composite milk powder capable of being eaten and made into beautifying face mask

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
生物粘附凝胶剂的研究现养. 青云.中国医药报. 2003 *
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI637747B (en) * 2017-06-19 2018-10-11 大江生醫股份有限公司 A composition comprising young watermelon fruit extract, young chiapao melon fruit extract or combination thereof having functionality to regulate the gene expression of interleukin-8, nitric oxide synthase 3, endothelin 1, tissue type-plasminogen activa

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