CN100356950C - Bitter buccal tablet for clearing and moistening throat - Google Patents
Bitter buccal tablet for clearing and moistening throat Download PDFInfo
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- CN100356950C CN100356950C CNB200510019326XA CN200510019326A CN100356950C CN 100356950 C CN100356950 C CN 100356950C CN B200510019326X A CNB200510019326X A CN B200510019326XA CN 200510019326 A CN200510019326 A CN 200510019326A CN 100356950 C CN100356950 C CN 100356950C
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- buccal tablet
- folium ilicis
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Abstract
The present invention relates to a bitter throat clearing and moistening sugar buccal tablet of which the part by weight of each raw material comprises 10 to 30 parts of bitter leaves tea, 5 to 25 parts dandelion herb, 5 to 25 parts Chinese white olive, 1 to 20 parts of houttuynia herb, 1 to 20 parts of chrysanthemum flower, 1 to 20 parts of green tea and 100 to 200 parts of isomaltitol. The material can also use balsam pear to replace the broadleaf holly leaf. The buccal tablet produced by the raw materials of the prescription has the advantages of sugar free, bitter taste, obvious effects on clearing and moistening throat, simple production process and moderate price, and is benefit for customers to take.
Description
Technical field
The present invention relates to a kind of buccal tablet for clearing and moistening throat of tool bitterness.
Background technology
The bottleneck throat common disease, even main drying, pain, hoarseness aphonia with pharynx and larynx, or the few expectorant of itching of the throat, dry cough, or dysphagia, or bottleneck throat foreign body sensation is arranged is main performance, can stimulate initiations such as (tobacco and wine, dust, chemical gas etc.), pronunciation be improper by pathogenic microorganism infection, foreign object.Doctor trained in Western medicine generally waits with tabellae iodi gurgitis cleaning throat and moistening larynx alleviates discomfort, the difficult purpose that reaches healing.The Chinese medicine food materials have superiority on solution throat problem, if can give full play to the advantage of Chinese medicine on the basis of theory of Chinese medical science, develop the product of better efficacy, society that can obtain and economic benefit.
Buccal tablet can directly act on the affected part the long time, has become the favorite product type of laryngopharyngeal diseases patient of dysphagia.Have the buccal tablet of many cleaning throat and moistening larynx in the market, the certain therapeutic effect of they each tools has solved the needs of people to the treatment laryngopharyngeal diseases to a certain extent.But in the buccal tablet that has gone on the market, mostly be sugar-containing product, this has brought satisfactory to both parties difficulty for the patient that should not eat sugar more.Therefore, the sugar-free of developing various tastes wets one's whistle, and to become society required for product.
Summary of the invention
The technical problem to be solved in the present invention provides buccal tablet a kind of bitterness, that good cleaning throat and moistening larynx function is arranged.
The present invention solves the problems of the technologies described above with following technical scheme:
The composition of primary raw material of the present invention and deal are (weight portion):
1～20 part of 5～25 parts of Herba Houttuyniae of 5～25 portions of Fructus Canariis of 10～30 parts of Herba Taraxacis of Folium Ilicis
100～200 parts of 1～20 part of hydroxyl isomaltuloses of 1～20 portion of green tea of Flos Chrysanthemi
Fructus Momordicae charantiae can be replaced Folium Ilicis in the above-mentioned raw materials.
Manufacturing is that the method for the product of prescription is with the above-mentioned raw materials:
1, gets Folium Ilicis (or Fructus Momordicae charantiae), Herba Taraxaci, Fructus Canarii, Herba Houttuyniae, Flos Chrysanthemi, green tea, choose decontamination, clean.
2, the above-mentioned Six-element material of Xi Jinging decocts with water, and filters, and filtrate is concentrated into thick paste, and is standby.
3, the pure and mild water of lysed isomaltulose adds above-mentioned thick paste and stirs to heating also, filters, with filtrate heating evaporation, vacuum concentration.
4, the cooling, tabletting, pack finished product.
Buccal tablet with method of the present invention is produced does not contain sugar, bitter in the mouth, and the cleaning throat and moistening larynx effect is remarkable, and production technology is simple, and moderate cost is beneficial to consumer and takes.
The specific embodiment
Because Chinese crude drug is taken from natural animals and plants or natural minerals, drug effect is obvious, few side effects, all very pays close attention to the development and use of various Chinese medicines at all times.To the following Chinese medicine of respectively distinguishing the flavor of, pharmacy circle has had common recognition:
Folium Ilicis is the leaf of holly plant Ilex cornuta Lindl. Ilex cornuta Lindl. and Cortex Ilicis Rotundae Ilex latifolia Thunb..Sweet after the sweet cold of flavour, promoting the production of body fluid to quench thirst, the elder generation's hardship.Folium Ilicis has functions such as heat-clearing and toxic substances removing, antiinflammatory be convenient, and is remarkable to disease effects such as laryngopharynx swelling and pain, stomatitis, gingivitiss.
Fructus Momordicae charantiae is the fruit of cucurbitaceous plant Fructus Momordicae charantiae Momordica charantia L..Fructus Momordicae charantiae is cold in nature, and bitter in the mouth has antipyretic and antidote functions preferably.Its contained bitter principle---quinine can suppress overwrought heat center, has the trivial solution heat effect.Its extracting solution has the function that suppresses various bacteria, comprises gram-positive cocci, bacillus and gram negative bacilli etc., so become natural broad-spectrum antiseptic food.Modern medicine study proves, multiple efficacies such as anticancer, antibiotic, clear inflammation that Fructus Momordicae charantiae has, antiviral, raising immunity.Can be used for diseases such as treatment laryngalgia, xerostomia.
Fructus Canarii is the dry mature fruit of olive subject plant Fructus Canarii albi Canarium album Raeusch.." Chinese pharmacopoeia one one of version in 2005 is carried: heat clearing away, sore-throat relieving promotes the production of body fluid, detoxifcation.Be used for laryngopharynx swelling and pain, cough, excessive thirst.
Herba Taraxaci is the dry herb of feverfew Herba Taraxaci Taraxacum mongolicum Hand.-Mazz., alkali ground Herba Taraxaci Taraxacum sinicum Kitag..Bitter in the mouth, sweet, cold.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.Be used for pharyngalgia, diseases such as conjunctival congestion.
Herba Houttuyniae is the dry aerial parts of saururaceae plant houttuynia cordata Houttuynia cordata Thunb..Suffering is slightly cold.Heat-clearing and toxic substances removing, the eliminating carbuncle evacuation of pus.Be used for the lung abscess vomiting pus, the expectorant dyspnea of heat type is coughed, diseases such as carbuncle sore tumefacting virus.
Flos Chrysanthemi is the dry capitulum of feverfew chrysanthemum Chrysanthemum morifolium Ramat..Sweet, bitter, be slightly cold.Diffusing wind heat clearing away, suppressing the hyperactive liver makes eye bright.Be used for anemopyretic cold, it is dizzy to have a headache, conjunctival congestion and swelling pain, and eyes is dim-sighted.
Green tea mainly contains theanine, tea polyphenols etc. in the Folium Camelliae sinensis.External one studies show that, theanine can promote the invasion and attack generation immunoreation of pathogenic microorganism to external world of T lymphocyte at the intravital catabolite of people, can also promote the secretion of interferon simultaneously.Tea polyphenols has antioxidation, anticancer change, antiinflammatory is antibacterial and eliminate effect such as foreign odor.Can strengthen the extraneous ability that infects of respiratory tract opposing.
This buccal tablet for clearing and moistening throat, make with the raw material of following weight portion:
1～20 part of 5～25 parts of Herba Houttuyniae of 5～25 portions of Fructus Canariis of 10～30 parts of Herba Taraxacis of Folium Ilicis
100～200 parts of 1～20 part of hydroxyl isomaltuloses of 1～20 portion of green tea of Flos Chrysanthemi
Can replace Folium Ilicis with Fructus Momordicae charantiae in the above-mentioned raw materials.
The method of making above formulation product is:
1, gets Folium Ilicis (or Fructus Momordicae charantiae), Herba Taraxaci, Fructus Canarii, Herba Houttuyniae, Flos Chrysanthemi, green tea, choose decontamination, clean.
2, the above-mentioned Six-element material of Xi Jinging decocts with water the merging of twice, twice filtrate, filters, and filtrate is concentrated into relative density and is 1.20～1.35 thick pastes, and is standby.
3, the pure and mild water Hybrid Heating of isomaltulose is made its dissolving, add the thick paste and the after-filtration that stirs, filtrate is heated to 140～155 ℃ of evaporations, vacuum concentration.
4, the cooling, tabletting, pack finished product.
The investigation of product clinical efficacy
1. case choice criteria
1.1 diagnostic criteria
Symptom: even dry laryngopharynx, pain, hoarseness aphonia, or itching of the throat, the few expectorant of dry cough, dysphagia, bottleneck throat has foreign body sensation.
1.2 the standard of including in
1. meet above-mentioned diagnostic criteria person.
2. the age is 18-65 year person.
1.3 exclusion standard
1.3.1 do not meet above-mentioned tcm diagnosis standard person.
Though, have one of following situation person simultaneously 1.3.2 meet above-mentioned differential diagnosis in tcm standard:
1. the age is at under-18s, or the over-65s person.
2. pregnant and lying-in women or women breast-feeding their children.
3. be associated with serious primary disease such as cardiovascular, liver, kidney and hemopoietic system, the psychotic.
4. all standards of including in that do not meet, not medication in accordance with regulations can't be judged that curative effect or data are not congruent to affect the treatment and safety judgement person.
2. efficacy determination
(1) 1 week disappeared or basic the disappearance with interior clinical symptoms, sign with interior sx in 3 days in the clinical recovery medication.
(2) 1 week of produce effects medication is with interior sx, and 2 weeks disappeared or basic the disappearance with interior clinical symptoms, sign.
(3) effectively 2 weeks, most of sign disappeared with interior clinical symptom relief with interior sx 1 week of medication.
(4) after the invalid medication symptom have slightly alleviate or do not have alleviate, sign do not have obvious improvement.
3. medication
Get the product of embodiment 1, suck clothes, an a slice, six times on the one.
Product curative effect survey result table
| Sum | Clinic control | Produce effects | Effectively | Invalid | |
| The example number | 186 | 112 | 39 | 32 | 3 |
| Shared percent | 60.2％ | 21.0％ | 17.2％ | 1.6％ |
Embodiment 1
Prescription: Folium Ilicis 75g Herba Taraxaci 38g Fructus Canarii 30g Herba Houttuyniae 22g Flos Chrysanthemi 15g
Green tea 15g hydroxyl isomaltulose 950g
The method of making above formulation product is:
1, get Folium Ilicis, Herba Taraxaci, Fructus Canarii, Herba Houttuyniae, Flos Chrysanthemi, green tea, choose decontamination, water cleans twice respectively.
2, above-mentioned Six-element is expected only, decocts with water twice, for the first time adds 12 times of amounts, decocts 1.5 hours, adds 10 times of amounts for the second time, decocted 1.5 hours, and filtration, merging filtrate is concentrated into the thick paste of relative density 1.25-1.30 (60 ℃), and is standby.
3, add the pure and mild water of isomaltulose in the interlayer decoction pot, heating makes its dissolving, adds above-mentioned thick paste and stirs, filter, filtrate is imported in the vacuum continuous pan boiling pot heating evaporation, vaporization chamber thick paste temperature should reach 145-150 ℃ at short notice, makes that most of moisture content can evaporate in the thick paste; Vacuum concentration, being pressed into after concentrating changes in the pot.
4, cooling, tabletting, every heavy 2g.
Embodiment 2
Prescription: Folium Ilicis 110g Herba Taraxaci 90g Fructus Canarii 50g Herba Houttuyniae 10g Flos Chrysanthemi 8g
Green tea 30g hydroxyl isomaltulose 600g
The method of making above formulation product is:
1. step 1 is with embodiment 1.
2. above-mentioned Six-element is expected only, decocts with water twice, for the first time adds 10 times of amounts, decocts 2 hours, adds 8 times of amounts for the second time, decocted 1.5 hours, and filtration, merging filtrate is concentrated into the thick paste of relative density 1.20-1.25 (60 ℃), and is standby.
3, step 3 is with embodiment 1.Vaporization chamber thick paste temperature should reach 140-145 ℃ at short notice.
4, cooling, tabletting, every heavy 2.5g.
Embodiment 3
Prescription: Folium Ilicis 140g Herba Taraxaci 25g Fructus Canarii 70g Herba Houttuyniae 50g Flos Chrysanthemi 50g
Green tea 45g hydroxyl isomaltulose 500g
The method of making above formulation product is:
1, step 1 is with embodiment 1.
2 above-mentioned Six-elements are expected only, decoct with water twice, for the first time add 10 times of amounts, decoct 2.5 hours, add 9 times of amounts for the second time, decocted 2 hours, and filtration, merging filtrate is concentrated into the thick paste of relative density 1.25-1.30 (60 ℃), and is standby.
3, step 3 is with embodiment 1.Vaporization chamber thick paste temperature should reach 145-150 ℃ at short notice.
4, cooling, tabletting, every heavy 3g.
Embodiment 4
Prescription: Folium Ilicis 50g Herba Taraxaci 40g Fructus Canarii 65g Herba Houttuyniae 70g Flos Chrysanthemi 90g
Green tea 90g hydroxyl isomaltulose 800g
The method of making above formulation product is:
1, step 1 is with embodiment 1.
2, above-mentioned Six-element is expected only, decocts with water twice, for the first time adds 12 times of amounts, decocts 2 hours, adds 12 times of amounts for the second time, decocted 1.5 hours, and filtration, merging filtrate is concentrated into the thick paste of relative density 1.30-1.35 (60 ℃), and is standby.
3, step 3 is with embodiment 1.Vaporization chamber thick paste temperature should reach 150-155 ℃ at short notice.
4, cooling, tabletting, every heavy 1.5g.
Embodiment 5
Prescription: Fructus Momordicae charantiae 95g Herba Taraxaci 65g Fructus Canarii 88g Herba Houttuyniae 90g Flos Chrysanthemi 70g
Green tea 60g hydroxyl isomaltulose 650g
The method of making above formulation product is:
1, step 1 is with embodiment 1.
2, above-mentioned Six-element is expected only, decocts with water twice, for the first time adds 8 times of amounts, decocts 1.5 hours, adds 8 times of amounts for the second time, decocted 1 hour, and filtration, merging filtrate is concentrated into the thick paste of relative density 1.20-1.25 (60 ℃), and is standby.
3, step 3 is with embodiment 1.
4, cooling, tabletting, every heavy 1.8g.
Embodiment 6
Prescription: Fructus Momordicae charantiae 55g Herba Taraxaci 120g Fructus Canarii 115g Herba Houttuyniae 80g Flos Chrysanthemi 30g
Green tea 10g hydroxyl isomaltulose 900g
The method of making above formulation product is:
1, step 1 is with embodiment 1.
2, above-mentioned Six-element is expected only, decocts with water twice, for the first time adds 12 times of amounts, decocts 1.5 hours, adds 10 times of amounts for the second time, decocted 1.5 hours, and filtration, merging filtrate is concentrated into the thick paste of relative density 1.25-1.30 (60 ℃), and is standby.
3, step 3 is with embodiment 3.
4, cooling, tabletting, every heavy 2.2g.
Claims (4)
1, a kind of bitter buccal tablet for clearing and moistening throat is characterized in that being made by following bulk drugs: 100～200 parts of 1～20 part of hydroxyl isomaltuloses of 1～20 portion of green tea of 1～20 part of Flos Chrysanthemi of 5～25 parts of Herba Houttuyniae of 5～25 portions of Fructus Canariis of 10～30 parts of Herba Taraxacis of Folium Ilicis.
2, bitter buccal tablet for clearing and moistening throat as claimed in claim 1 is characterized in that replacing Folium Ilicis with Fructus Momordicae charantiae.
3. the preparation method of a bitter buccal tablet for clearing and moistening throat is characterized in that:
The weight portion of each crude drug is:
1～20 part of 5～25 parts of Herba Houttuyniae of 5～25 portions of Fructus Canariis of 10～30 parts of Herba Taraxacis of Folium Ilicis
100～200 parts of 1～20 part of hydroxyl isomaltuloses of 1～20 portion of green tea of Flos Chrysanthemi;
Preparation technology:
(1) gets Folium Ilicis, Herba Taraxaci, Fructus Canarii, Herba Houttuyniae, Flos Chrysanthemi, green tea, choose decontamination, clean;
(2) the above-mentioned Six-element material of Xi Jinging decocts with water, and filters, and filtrate is concentrated into thick paste, and is standby;
(3) add the pure and mild water of isomaltulose to thick paste, heating makes its dissolving and stirs, and filters, with filtrate heating evaporation, vacuum concentration;
(4) cooling, tabletting, pack finished product.
4, the preparation method of bitter buccal tablet for clearing and moistening throat as claimed in claim 3 is characterized in that replacing Folium Ilicis with Fructus Momordicae charantiae.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB200510019326XA CN100356950C (en) | 2005-08-18 | 2005-08-18 | Bitter buccal tablet for clearing and moistening throat |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB200510019326XA CN100356950C (en) | 2005-08-18 | 2005-08-18 | Bitter buccal tablet for clearing and moistening throat |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1733146A CN1733146A (en) | 2006-02-15 |
| CN100356950C true CN100356950C (en) | 2007-12-26 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB200510019326XA Expired - Fee Related CN100356950C (en) | 2005-08-18 | 2005-08-18 | Bitter buccal tablet for clearing and moistening throat |
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Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101331902B (en) * | 2007-06-29 | 2012-01-11 | 刘宝义 | Throat-cleaning health tea |
| CN102090493B (en) * | 2011-01-13 | 2012-10-10 | 浙江大学城市学院 | Preparation method of healthcare herbal candy containing traditional Chinese medicine components |
| CN102972599A (en) * | 2012-12-03 | 2013-03-20 | 陶杨杨 | Throat-wetting herbal tea and preparation method thereof |
| CN103843926A (en) * | 2014-02-11 | 2014-06-11 | 毛庆云 | Sugar-free broadleaf holly leaf buccal tablet and preparation method thereof |
| CN103960401B (en) * | 2014-05-30 | 2016-06-01 | 南京信息工程大学 | A kind of Chinese olive green tea instant drinks and its preparation method |
| CN104041650B (en) * | 2014-06-25 | 2017-04-19 | 雷允上药业集团有限公司 | Heat-removing throat-smoothing lozenges containing traditional Chinese medicine plant extracts and preparation method thereof |
| CN104041649B (en) * | 2014-06-25 | 2017-04-19 | 雷允上药业集团有限公司 | Breath-freshening and throat-wetting sugar containing Chinese medicinal herb extracts and preparation method of breath-freshening and throat-wetting sugar |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1457663A (en) * | 2003-06-05 | 2003-11-26 | 曹辉 | Compound prepared tea and its preparing method |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1457663A (en) * | 2003-06-05 | 2003-11-26 | 曹辉 | Compound prepared tea and its preparing method |
Non-Patent Citations (1)
| Title |
|---|
| 利咽逐瘀汤治疗急性扁桃腺炎378例 张宏伟.陕西中医，第16卷第10期 1995 * |
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| CN1733146A (en) | 2006-02-15 |
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