CN114869968A - Throat-moistening paste and preparation method thereof - Google Patents

Abstract

A throat moistening paste is prepared from principal drug (radix Panacis Quinquefolii, radix Platycodi), ministerial drug, adjuvant drug, and messenger drug; the ministerial drugs are mint, fructus momordicae and liquorice; the adjuvant drug is fragrant solomonseal rhizome. The throat moistening paste has effects of invigorating qi, nourishing yin, relieving sore throat and moistening throat. The method is particularly suitable for people who work in languages, such as teachers, actors, singers and the like.

Description

Throat-moistening paste and preparation method thereof

Technical Field

The invention belongs to the field of medicinal and edible foods, and particularly relates to throat-moistening paste and a preparation method thereof.

Background

Pharyngitis is a common clinical disease, is inflammation of pharyngeal mucosa and tissues below the mucosa, is part of upper respiratory tract infection, is a main clinical manifestation of pharyngeal swelling and pain, and can cause irritable cough due to sticky phlegm adhesion on the pharyngeal posterior wall. The disease is caused by virus infection, bacterial infection and environmental stimulation, and the number of patients is on the rise due to the increasing air pollution degree and the popularization and use of air conditioners in recent years. People with different degrees of pharyngitis account for 40% of healthy people, and the proportion of white-collar patients with pharyngitis is larger due to irregular diet, overlarge working intensity, poor office environment and the like.

Chinese patent document CN104547682A discloses a composition with the efficacy of clearing lung, relieving sore throat, moistening throat and relieving asthma. The method comprises the following steps: 5-15 parts of momordica grosvenori, 5-15 parts of oroxylum indicum, 5-10 parts of lily, 10-20 parts of bulbus fritillariae cirrhosae, 5-15 parts of radix ophiopogonis, 20-30 parts of bamboo juice, 10-30 parts of dendrobe, 5-15 parts of platycodon grandiflorum, 5-15 parts of pericarpium citri reticulatae, 5-15 parts of schizonepeta, 5-15 parts of divaricate saposhnikovia root, 5-15 parts of flos farfarae and 3-9 parts of liquorice. The composition can be administered orally or by inhalation, and can be used for relieving symptoms of common cold, aversion to cold, dry and dumb throat, cough with excessive phlegm, stagnation of qi, dyspnea, stuffy feeling in chest, expectoration, dry mouth, and tongue.

Chinese patent document CN102960496A discloses a throat-moistening green tea bag, which comprises the following raw materials in parts by weight: 55-63 parts of Laoshan green-baked green tea, 8-11 parts of liquorice, 9-12 parts of radix ophiopogonis, 7-10 parts of salvia miltiorrhiza, 5-7 parts of radix glehniae and 3-5 parts of wild buckwheat. The weight parts of the raw materials are as follows: preferably 60 parts of Laoshan green-baked green tea, 10 parts of liquorice, 10 parts of radix ophiopogonis, 10 parts of salvia miltiorrhiza, 6 parts of radix glehniae and 4 parts of wild buckwheat. The throat-benefiting and moistening green tea bag has the advantages of throat benefiting, fluid production promoting, thirst quenching, refreshing and consciousness restoring effects, convenience in drinking, strong tea fragrance, long-lasting aftertaste and unique taste, and is a green beverage which can be drunk in the morning and at night all the year round.

However, the invention still has the defects of bad taste, inconvenient taking, poor prevention and treatment effect and the like.

Disclosure of Invention

Aiming at the defects of the prior art, the invention provides throat-moistening paste and a preparation method thereof.

The technical scheme of the invention is as follows:

a throat moistening paste is prepared from principal drug (radix Panacis Quinquefolii, radix Platycodi), ministerial drug, and adjuvant drug; the ministerial drugs are mint, fructus momordicae and liquorice; the adjuvant drug is fragrant solomonseal rhizome. The ointment formula comprises the following components in parts by weight:

60-100 parts of American ginseng, 60-80 parts of platycodon grandiflorum, 60-80 parts of mint, 90-100 parts of momordica grosvenori, 30-60 parts of liquorice and 50-80 parts of polygonatum.

Further preferably, the ointment formula comprises the following components in parts by weight:

80 parts of American ginseng, 70 parts of platycodon grandiflorum, 70 parts of mint, 95 parts of momordica grosvenori, 45 parts of liquorice and 65 parts of polygonatum.

The preparation method of the throat-moistening paste is characterized by comprising the following steps:

(1) sorting

Weighing the following raw materials in parts by weight: 60-100 parts of American ginseng, 60-80 parts of platycodon grandiflorum, 60-80 parts of mint, 90-100 parts of momordica grosvenori, 30-60 parts of liquorice and 50-80 parts of polygonatum;

(2) medicine soaking

Cleaning radix Panacis Quinquefolii, radix Platycodi, herba Menthae, fructus Siraitiae Grosvenorii, Glycyrrhrizae radix, and rhizoma Polygonati Odorati with water, placing into casserole, adding cold water for soaking for 12-36 hr until the water amount is 15 cm higher than the medicinal surface;

(3) extraction of

Heating the soaked materials for 3 hr, decocting for 3 hr, adding water, decocting for 3 hr, repeating for 2-4 times, mixing the decoctions, standing for 6-12 hr, filtering with 100 mesh filter screen, removing impurities, and collecting clear decoction;

(4) concentrating

Heating the clarified liquid medicine to boil, and skimming froth; decocting with slow fire, evaporating, concentrating, and stirring to prevent coking until it gradually becomes thick paste;

(5) recovery cream

Continuously stirring the concentrated medicinal liquid until the gelatin block is completely melted, and continuously heating and stirring to obtain soft extract;

(6) dispensing

Quickly pouring the soft extract into a special container which is cleaned and disinfected in advance;

(7) cold cream

Cooling the packaged soft extract in purified environment for 12-24 hr, sealing, and packaging.

And (3) analysis of the prescription:

monarch drug: american ginseng and platycodon root.

American ginseng, also known as American ginseng, is a high-grade health care product which is tonic but not dry and suitable for all people, and is mainly produced in North America countries such as America, Canada and the like. Has effects in invigorating qi, nourishing yin, clearing away heat, and promoting salivation. Can be used for treating deficiency of qi and yin, internal heat, dry mouth and throat, asthenia heat, vexation, fatigue, diabetes, etc. The balloonflower root has the functions of dispersing lung qi, relieving sore throat, eliminating phlegm and expelling pus. Can be used for treating cough with excessive phlegm, chest distress, pharyngalgia, hoarseness, lung carbuncle, suppuration, pyocutaneous disease, suppuration, and ulcer. The combination of the two can clear heat, promote fluid production and relieve sore throat, and promote the discharge of a small amount of phlegm in the throat.

Ministerial drugs: herba Menthae, fructus Siraitiae Grosvenorii, and Glycyrrhrizae radix

The mint is pungent in flavor and cool in nature, and can disperse wind and heat, clear heat and promote eyesight, relieve sore throat and promote eruption, and sooth liver and promote qi circulation. The compendium of materia Medica records: mint, pungent in flavor and cool in flavor can disperse and clear and is used for dispelling wind and dissipating heat. So it is the key herb for headache, wind syndrome of head, eye, throat and mouth, infantile convulsions, scrofula, sores and scabies. For throat discomfort diseases, the mint can cool and moisten the throat. Fructus momordicae has the effects of clearing heat, moistening lung, relieving sore throat, easing voice and lubricating intestines and relaxing bowels, and is mainly used for lung heat dry cough, pharyngalgia, aphonia and constipation due to intestinal dryness. The raw licorice root can clear away heat and toxic material, dispel phlegm and relieve cough. The combination of the three medicines can clear heat, relieve sore throat and stop pain, and can promote the production of body fluid and moisten throat, and the three medicines are ministerial medicines together.

Adjuvant drugs: radix polygonati officinalis

Yuzhu can nourish yin, moisten dryness, promote the production of body fluid and quench thirst. It mainly enters lung and stomach meridians. Can be used for relieving heat dry cough with little phlegm, hemoptysis, and hoarseness. The polygonatum assists the monarch drug to promote the secretion of saliva or body fluid and relieve sore throat as an adjuvant drug.

The above components have effects of invigorating qi, nourishing yin, relieving sore throat and moistening throat.

Advantageous effects

The American ginseng selected by the invention has the effects of tonifying qi and nourishing yin, and combines the liquorice and the platycodon root, and the mint, the polygonatum and the momordica grosvenori which are commonly used as medicaments for relieving sore throat and promoting the production of body fluid, so that the effects of tonifying qi, nourishing yin, relieving sore throat and moistening throat can be achieved. The method is particularly suitable for people who work in languages, such as teachers, actors, singers and the like.

Detailed Description

The technical solution of the present invention is further described with reference to the following examples, but the scope of the present invention is not limited thereto.

Example 1

A throat moistening paste is prepared from principal drug (radix Panacis Quinquefolii, radix Platycodi), ministerial drug, and adjuvant drug; the ministerial drugs are mint, fructus momordicae and liquorice; the adjuvant drug is fragrant solomonseal rhizome. The ointment formula comprises the following components in parts by weight:

60 parts of American ginseng, 80 parts of platycodon grandiflorum, 60 parts of mint, 100 parts of momordica grosvenori, 30 parts of liquorice and 80 parts of polygonatum.

The preparation method of the throat-moistening paste is characterized by comprising the following steps:

(1) sorting

Weighing the following raw materials in parts by weight: 60 parts of American ginseng, 80 parts of platycodon grandiflorum, 60 parts of mint, 100 parts of momordica grosvenori, 30 parts of liquorice and 80 parts of polygonatum.

(2) Medicine soaking

Cleaning radix Panacis Quinquefolii, radix Platycodi, herba Menthae, fructus Siraitiae Grosvenorii, Glycyrrhrizae radix, and rhizoma Polygonati Odorati with water, placing into casserole, adding cold water for soaking for 12 hr until the water amount is 15 cm higher than the medicinal surface;

(3) extraction of

Heating the soaked materials, decocting for 3 hr, taking out the decoction, adding water, decocting for 3 hr, taking out the decoction, repeating for 2 times, mixing the decoctions, standing for 6 hr, filtering with 100 mesh filter screen, removing impurities, and taking out the clarified decoction;

(4) concentrating

Heating the clarified liquid medicine to boil, and skimming froth; decocting with slow fire, evaporating, concentrating, and stirring to prevent coking until it gradually becomes thick paste;

(5) recovery cream

Continuously stirring the concentrated medicinal liquid until the gelatin block is completely melted, and continuously heating and stirring to obtain soft extract;

(6) dispensing

Quickly pouring the soft extract into a special container which is cleaned and disinfected in advance;

(7) cold cream

Cooling the packaged soft extract in purified environment for 12 hr, sealing, and packaging.

Example 2

A throat moistening paste is prepared from principal drug (radix Panacis Quinquefolii, radix Platycodi), ministerial drug, and adjuvant drug; the ministerial drugs comprise herba Menthae, fructus Siraitiae Grosvenorii, and Glycyrrhrizae radix; the adjuvant drug is fragrant solomonseal rhizome. The ointment formula comprises the following components in parts by weight:

80 parts of American ginseng, 70 parts of platycodon grandiflorum, 70 parts of mint, 95 parts of momordica grosvenori, 45 parts of liquorice and 65 parts of polygonatum.

The preparation method of the throat-moistening paste is characterized by comprising the following steps:

(1) sorting

Weighing the following raw materials in parts by weight: 80 parts of American ginseng, 60 parts of platycodon grandiflorum, 60 parts of mint, 90 parts of momordica grosvenori, 30 parts of liquorice and 60 parts of polygonatum.

(2) Medicine soaking

Cleaning radix Panacis Quinquefolii, radix Platycodi, herba Menthae, fructus Siraitiae Grosvenorii, Glycyrrhrizae radix, and rhizoma Polygonati Odorati with water, placing into casserole, adding cold water for soaking for 24 hr until the water amount is 15 cm higher than the medicinal surface;

(3) extraction of

Heating the soaked materials, decocting for 3 hr, taking out the decoction, adding water, decocting for 3 hr, taking out the decoction, repeating for 3 times, mixing the decoctions, standing for 8 hr, filtering with 100 mesh filter screen, removing impurities, and taking out the clarified decoction;

(4) concentrating

Heating the clarified liquid medicine to boil, and skimming froth; decocting with slow fire, evaporating, concentrating, and stirring to prevent coking until it gradually becomes thick paste;

(5) recovery cream

Continuously stirring the concentrated medicinal liquid until the gelatin block is completely melted, and continuously heating and stirring to obtain soft extract;

(6) dispensing

Quickly pouring the soft extract into a special container which is cleaned and disinfected in advance;

(7) cold cream

Cooling the packaged soft extract in purified environment for 18 hr, sealing, and packaging.

Example 3

A throat moistening paste is prepared from principal drug (radix Panacis Quinquefolii, radix Platycodi), ministerial drug, and adjuvant drug; the ministerial drugs are mint, fructus momordicae and liquorice; the adjuvant drug is fragrant solomonseal rhizome. The ointment formula comprises the following components in parts by weight:

100 parts of American ginseng, 60 parts of platycodon grandiflorum, 80 parts of mint, 90 parts of momordica grosvenori, 60 parts of liquorice and 50 parts of polygonatum.

The preparation method of the throat-moistening paste is characterized by comprising the following steps:

(1) sorting

Weighing the following raw materials in parts by weight: 100 parts of American ginseng, 60 parts of platycodon grandiflorum, 80 parts of mint, 90 parts of momordica grosvenori, 60 parts of liquorice and 50 parts of polygonatum.

(2) Medicine soaking

Cleaning radix Panacis Quinquefolii, radix Platycodi, herba Menthae, fructus Siraitiae Grosvenorii, Glycyrrhrizae radix, and rhizoma Polygonati Odorati with water, placing into casserole, adding cold water for soaking for 36 hr, wherein the water amount is 15 cm higher than the medicinal surface;

(3) extraction of

Heating and decocting the soaked materials for 3 hr, taking out the decoction, adding water, decocting for 3 hr, taking out the decoction, repeating for 4 times, mixing the decoctions, standing for 12 hr, filtering with 100 mesh filter screen, removing impurities, and taking out the clarified decoction;

(4) concentrating

Heating the clarified liquid medicine to boil, and skimming froth; decocting with slow fire, evaporating, concentrating, and stirring to prevent coking until it gradually becomes thick paste;

(5) recovery cream

Continuously stirring the concentrated medicinal liquid until the gelatin block is completely melted, and continuously heating and stirring to obtain soft extract;

(6) dispensing

Quickly pouring the soft extract into a special container which is cleaned and disinfected in advance;

(7) cold cream

Cooling the packaged soft extract in purified environment for 24 hr, sealing, and packaging.

Examples of the experiments

The experimental population is from patients in subhealth outpatients of national medical center of imperial hall, the selection standard is that male and female patients are examined to have no organic lesions and are only in subhealth state, 33 patients with pharyngeal discomfort are received in two months of 5-11 months in 2021, and 30 patients after taking the throat moistening cream for two months show that the pharyngeal discomfort is obviously relieved. The effective rate is 90.9%.

Typical patients are:

patient 1

Liu is certain, women are 33 years old, and primary school teachers often feel dry, astringent and itchy throat and even pain in class, people often soak oroxylum indicum, radix ophiopogonis and other tea drinks to improve symptoms to a certain extent, and patients do not see relief treatment in half a month after 6 months in 2021 because throat discomfort symptoms occur, check that the tongue tip is slightly red, the tongue fur is thin and white, the throat is slightly congested, and the tonsil is not large, which is insufficient body fluid and upward disturbance of deficient fire, take the throat moistening cream for conditioning in consideration of the long-term condition of her state of illness, take 10 g of the throat moistening cream every day, patients feel salubrious in the throat after three days, insist on taking half-month symptoms if the patients lose the throat moistening cream, and insist on taking the throat moistening cream for a long time, and basically control the throat discomfort symptoms.

Patient 2

A certain Liangqi woman, age 29, a supermarket cashier, who is engaged in the work for nearly 1 year, often gets dry in throat due to more speech, can obviously relieve the symptoms by drinking more water or Chinese-style throat moistening tablets at the beginning, and continuously changes two or three throat moistening pastes for nearly three months, so that the symptoms cannot be well controlled, the traditional Chinese medicine is transferred to check that the tongue is red, the coating is white and thick, the speaking mouth is heavy, the stool is sticky, the throat moistening paste is conditioned, the traditional Chinese medicine is taken 10 g every day, the symptoms are controlled after taking for one week, and the paste formula is taken discontinuously afterwards, so that the symptom control is good.

Patient 3

The traditional Chinese medicine composition is suitable for clearing and benefiting the throat, is prepared by conditioning throat moistening paste, is taken 10 g every day, and is ordered to strengthen physical exercise, light diet and reduce the intake of smoke and wine, and the patient feels salubrious and has a light symptom after taking a month, and the weight is reduced by nearly 3 jin after a week.

Patient 4

Yan A woman is 62 years old and retires at home, except that the woman is the place to receive and send the baby and the baby is the playing card, the history of pharyngitis is many years, the throat is itchy, and occasionally dry cough is the main reason, and the person needs to drink water frequently to moisten the throat. Patients with irritable and irritable spleen qi, normal eating, dreaminess in sleep, red tongue tip, thin and yellow fur, yellow urine, and normal stool. The throat moistening ointment is used for conditioning after diagnosing that fire is exuberant due to yin deficiency, the throat moistening ointment is taken 10 g every day, after 5 days, a patient shows that the throat is relatively cool and has reduced dryness, and after two weeks, the patient hardly feels uncomfortable throat, and the throat moistening ointment is continuously and discontinuously taken.

According to the experimental examples, the throat moistening paste prepared by the invention has good effects on pharyngeal discomfort symptoms such as pharyngalgia, excessive phlegm, hoarseness and the like. Meanwhile, the medicine is completely based on the medicine-food homologous theory, so that the safety is reliable and convincing.

The above-mentioned embodiments are only used for illustrating the technical solution of the present invention, and not for limiting the same; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.

Claims (4)

1. A throat-moistening paste is characterized by being prepared from monarch drug, ministerial drug, adjuvant drug and conductant drug, wherein the monarch drug is American ginseng and platycodon root; the ministerial drugs are mint, fructus momordicae and liquorice; the adjuvant drug is fragrant solomonseal rhizome.

2. The throat-moistening ointment of claim 1, wherein the ointment formula comprises the following components in parts by weight: 60-100 parts of American ginseng, 60-80 parts of platycodon grandiflorum, 60-80 parts of mint, 90-100 parts of momordica grosvenori, 30-60 parts of liquorice and 50-80 parts of polygonatum.

3. The throat-moistening ointment of claim 1, wherein the ointment is prepared from the following components in parts by weight: 80 parts of American ginseng, 70 parts of platycodon grandiflorum, 70 parts of mint, 95 parts of momordica grosvenori, 45 parts of liquorice and 65 parts of polygonatum.

4. The method for preparing a throat soothing paste according to claim 1, comprising the steps of:

(1) sorting

Weighing the following raw materials in parts by weight: 60-100 parts of American ginseng, 60-80 parts of platycodon grandiflorum, 60-80 parts of mint, 90-100 parts of momordica grosvenori, 30-60 parts of liquorice and 50-80 parts of polygonatum;

(2) medicine soaking

Cleaning radix Panacis Quinquefolii, radix Platycodi, herba Menthae, fructus Siraitiae Grosvenorii, Glycyrrhrizae radix, and rhizoma Polygonati Odorati with water, placing into casserole, adding cold water for soaking for 12-36 hr until the water amount is 15 cm higher than the medicinal surface;

(3) extraction of

Heating the soaked materials for 3 hr, decocting for 3 hr, adding water, decocting for 3 hr, repeating for 2-4 times, mixing the decoctions, standing for 6-12 hr, filtering with 100 mesh filter screen, removing impurities, and collecting clear decoction;

(4) concentrating

Heating the clarified liquid medicine to boil, and skimming froth; decocting with slow fire, evaporating, concentrating, and stirring to prevent coking until it gradually becomes thick paste;

(5) recovery cream

Continuously stirring the concentrated medicinal liquid until the gelatin block is completely melted, and continuously heating and stirring to obtain soft extract;

(6) dispensing

Quickly pouring the soft extract into a special container which is cleaned and disinfected in advance;

(7) cold cream

Cooling the packaged soft extract in purified environment for 12-24 hr, sealing, and packaging.