CN100341477C - Film patch for shading sun and treating eye wrinkles - Google Patents
Film patch for shading sun and treating eye wrinkles Download PDFInfo
- Publication number
- CN100341477C CN100341477C CNB2005100302708A CN200510030270A CN100341477C CN 100341477 C CN100341477 C CN 100341477C CN B2005100302708 A CNB2005100302708 A CN B2005100302708A CN 200510030270 A CN200510030270 A CN 200510030270A CN 100341477 C CN100341477 C CN 100341477C
- Authority
- CN
- China
- Prior art keywords
- skin
- sun
- layer
- treatment
- gel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Abstract
The present invention relates to a film patch for protecting the sun and treating eye wrinkles, which comprises a back lining layer for loading active constituents, a gel layer laid at the upper part of the back lining layer, and an anti-sticking layer covered on the gel layer. The film patch for protecting the sun and treating eye wrinkles disclosed by the present invention has the advantages that the eye film is researched and invented by aiming at the physiological and pharmacological characteristics of skin, and the eye film acts on the skin in sequence to open the channels of the skin; the film patch is composed of medicines for adjusting and controlling a skin barrier and medicines for conditioning the skin in order to obtain the purpose of transdermal absorption, and the effects on treating the texture and the wrinkles of the skin are obvious. Because the skin around people's eyes is tender and sensitive, the skin around the people's eyes is a main easy-generation part of aging, and the eye film can perform the functions of decoration and sun protection.
Description
Technical field
The present invention relates to the medical cosmetology field, specifically the present invention relates to a kind of sun-proof, the treatment eye wrinkle-removing diaphragm.
Background technology
Showing have fifty percent people to worry the matter of utmost importance of worried own skin condition in nearest Asia women's skin condition investigation report nearly, is exactly " wrinkle ".The skin of circumference of eyes is the weakest in the human body, because eye skin sweat gland and sebum distribution are less, skin is dry, so also be easy to generate most wrinkle.Eye wrinkle-removing is divided into three kinds from shallow to deep: the dry stricture of vagina that is caused by the horny layer hydropenia; Cause the wire stricture of vagina (claiming crows-feet usually) that has the acantholysis cell atrophy to produce because of the horny layer hydropenia; By the aging deep wrinkle that is produced of skin corium fiber.The method that many treatment eye wrinkle-removings are arranged at present, these treatments serve as the treatment principle to replenish the conditioning of moisture content and Chinese medicine generally, and because of the skin barrier problem, Chinese medicinal ingredients absorbs difficulty, and curative effect is limited; Present facial film technology does not consider that also failing to solve pharmaceutical compositions effectively absorbs problem.The treatment specific aim is not strong, is design with full face lamellar facial film at present, based on treatments such as mottles, no specific aims such as concrete a certain position wrinkle is treated in treatment.
Summary of the invention
The object of the present invention is to provide a kind of sun-proof, the treatment eye wrinkle-removing diaphragm.
The objective of the invention is to realize by following technical method:
A kind of sun-proof, the treatment eye wrinkle-removing diaphragm, comprising:
A backing layer that is used for load active component;
The gel layer on the backing layer top that is laid in;
An adherent layer that covers on the gel layer.
Described gel layer contains PVAC polyvinylalcohol-124, silica gel, hyaluronic acid, water.The component that gel layer contains is by weight percentage:
PVAC polyvinylalcohol-124 10-20%
Hyaluronic acid 20-30%
Silica gel 15-25%
Water surplus.
Described backing layer is for containing the aluminumpolyethylene composite membrane.
Scribble the individual character coloured picture on the described backing layer, be with three-dimensional figure ornament.
The adherent layer of being addressed is the polyester film of surface through the silicone oil release treatment.
This is sun-proof, the diaphragm of treatment eye wrinkle-removing comprises the backing layer that is used for load active component, be laid in backing layer top, contain the gel layer of PVAC polyvinylalcohol-124, silica gel, hyaluronic acid, water, cover the adherent layer that the polyester of the silicone-treated on the gel layer is made, remove before the use.
(1) a kind of sun-proof, the treatment eye wrinkle-removing diaphragm-operated preparation method, may further comprise the steps:
(1) glue: take PVAC polyvinylalcohol-124 to be gel-type vehicle, make rubber cement, mix behind adding silica gel, the hyaluronic acid, obtain gel after the cooling;
(2) gluing: above-mentioned gel is uniformly coated on the polyester adherent layer that silicone-treated crosses intensive drying;
(3) press seal: cover backing film, sealing is die-cut into suitable size, promptly gets diaphragm sun-proof, the treatment eye wrinkle-removing.
(2) a kind of sun-proof, the treatment eye wrinkle-removing diaphragm-operated preparation method, may further comprise the steps:
(1) glue: take PVAC polyvinylalcohol-124 to be gel-type vehicle, make rubber cement, mix behind adding silica gel, the hyaluronic acid, obtain gel after the cooling;
(2) gluing: above-mentioned gel is uniformly coated on the polyester adherent layer that silicone-treated crosses intensive drying;
(3) press seal: cover backing film, scribble the individual character coloured picture on the backing film, be with three-dimensional figure ornament, sealing is die-cut into suitable size, promptly gets diaphragm sun-proof, the treatment eye wrinkle-removing.
Zoopery of the present invention
1. the heavy Duroc of laboratory animal: 15kg is yellow by the hair piglets, and normal diet is fed can not be point-blank indoor in sunlight.
2. medicine: using polythene alcohol PVA-124 makes gel-type vehicle, medicine: hyaluronic acid.
3. Therapeutic Method: selecting Oculus sus domestica eyelid place skin is the Experimental Area, divides two groups, and (1) matched group sticks PVAC polyvinylalcohol-124 and makes gel.(2) contain the diaphragm of PVAC polyvinylalcohol-124, silica gel, hyaluronic sun-proof, treatment eye wrinkle-removing.
4. detection method: behind application treatment, two weeks, January, February, March, skin appearance is observed, got biopsy specimen respectively, formalin fixed, paraffin embedding, section, row HE dyeing.After histological observation and statistical analysis: the HE dyeing, light microscopic is observed the variation of different times piglets epiderm skin cell and papillary layer of corium collagen tissue down.Piglets normal skin group is organized in contrast, and graphical analysis is carried out in the section of each group different times, and the meter skin thickness is analyzed comparison with method of analysis of variance.
5. result:
One. skin tissue morphology is observed
Collagen tissue all has in various degree and thickens in the treatment group papillary layer of corium, and obvious collagen band appears in part, promptly so-called Grenz band, its thickness with the application treatment time and different, arrangement of collagen fibers trends towards neat densification.
Skin tissue morphology changes behind table 1 application treatment
| Medicine | Epidermal area | Papillary layer of corium | ||
| Time | Cell is arranged | Tightness degree | Collagen fiber | |
| The treatment group | Two weeks | ± | - | ± |
| January | + | ++ | + | |
| The bimester | + | ++ | + | |
| March | + | ++ | ++ | |
| Two weeks | + | - | ± | |
| Matched group | January | - | ± | - |
| The bimester | - | - | - | |
| March | - | - | ± | |
Annotate :-not obvious, irregular or disorderly; + neat, tight, clear, obvious
Two. the epidermal area thickness measure
Treatment group skin epidermis all thickened at one month, trended towards stablizing in two months.Three months very remarkable with normal skin epidermal area difference in thickness, and The results of analysis of variance shows, P＜0.05.
(the unit: μ m) of epidermal area thickness measure behind table 2 skin treating
| Treatment two weeks of back | January after the treatment | February after the treatment | March after the treatment | |
| The treatment group | 58.1490 | 63.5767 | 69.8896 | 74,9768 |
| Matched group | 55.9344 | 56.0481 | 55.7666 | 55.7932 |
(the unit: μ m) of collagen layer thickness measure behind table 3 skin treating
| Treatment one week of back | January after the treatment | February after the treatment | March after the treatment | |
| The treatment group | 11.987 | 15.981 | 18.629 | 21.523 |
| Matched group | 9.3211 | 9.2444 | 9.2956 | 9.4112 |
6. explanation
One. the arranging situation of epidermis cell directly has influence on the outward appearance and the quality of skin, marshalling, the skin smooth exquisiteness that seems.Simultaneously, the tightness degree of cell is related to the moisture-retaining capacity of skin, arranges the moisture content that closely can effectively prevent in the skin and runs off and evaporation, keeps the smooth and elasticity of skin.The observation of each treatment group epidermis cell is found to one, February, the situation ideal that cell is arranged has the outward appearance and the quality of advantages of good skin.
Two. the hypertrophy of collagen fiber and rearranging, can increase the substrate in the skin corium, improve the elastic fiber quality, improve tiny wrinkle, and the wrinkle in desalination deep, increase the elasticity and the gloss of skin.To the observation of treatment group collagen tissue, find that papillary layer of corium all has the collagen band to occur or collagen tissue thickens to some extent.
Three. epidermal area thickness has direct influence to skin quality, and epidermal area is blocked up, and it is dark and gloomy, matt that skin seems, epidermal area is thin excessively, and the skin sensitivity degree increases, and easily takes place irritated.The epidermal area of suitable thickness is the key factor that skin keeps optimum state.According to the measurement result of epidermal area thickness, can find after treatment, significantly to increase February the thickness of epidermal area.
Clinical research of the present invention
Clinical treatment grouping: outpatient service eye wrinkle-removing patient is divided into two groups at random.Group 1 contains the diaphragm of PVAC polyvinylalcohol-124, silica gel, hyaluronic sun-proof, treatment eye wrinkle-removing; Matched group, polyvinyl alcohol+silica gel compound.
The clinical treatment method: 1, by doctor's advice, stick wrinkle place near the eyes, about 12 hours every days.As dermatitis appears, the erythema allergy sufferers is picked out experimental group.Observe in addition;
2 followed up a case by regular visits in treatment two weeks, January, February, March, filled in the observation of curative effect table, comprised the subjective curative effect table of doctor's objective determination and patient, the comprehensive statistics curative effect.
The result: pick out 3 erythema allergy sufferers altogether, the curative effect statistics is as follows: as table 4
Table 4: curative effect statistics *
| Observing time | Curative effect | Grade | Group 1 | Matched group | ||
| Estimate (example) curative effect rate (%) | Estimate (example) | Curative effect rate (%) | ||||
| 2 weeks | Effectively | Wrinkle significantly improves | 9 | 28.75％ | 0 | 2.5％ |
| Wrinkle partly improves | 14 | 2 | ||||
| Invalid | Wrinkle does not have change | 57 | 71.25％ | 78 | 97.50％ | |
| 1 month | Effectively | Wrinkle significantly improves | 10 | 38.75％ | 0 | 1.25％ |
| Wrinkle partly improves | 21 | 1 | ||||
| Invalid | Wrinkle does not have change | 45 | 61.25％ | 79 | 98.75％ | |
| 2 months | Effectively | Wrinkle significantly improves | 22 | 63.75％ | 0 | 1.25％ |
| Wrinkle partly improves | 29 | 1 | ||||
| Invalid | Wrinkle does not have change | 29 | 36.25％ | 79 | 98.75％ | |
| 3 months | Effectively | Wrinkle significantly improves | 25 | 81.25％ | 0 | 1.25％ |
| Wrinkle partly improves | 40 | 1 | ||||
| Invalid | Wrinkle does not have change | 15 | 18.75％ | 79 | 98.75％ | |
| The observation number adds up to (example) | N＝80 | N＝80 | ||||
* statistical analysis: X
2Check, treatment group and matched group, P value＜0.01
The diaphragm of disclosed a kind of sun-proof, the treatment eye wrinkle-removing of the present invention, its advantage shows: at skin physiology and the research of pharmacology characteristics, invent this eye mask, act on skin in order, open the skin passage.Medicine and skin condition medicine by the skin barrier regulation and control are formed, and to reach the purpose of Transdermal absorption, treatment skin quality and wrinkle effect are remarkable.Because of skin of human eye circumference delicacy, sensitivity, be the aged main position of easily sending out, this eye mask can rise to be decorated and anti-sunlight function.
Description of drawings
Fig. 1 shows a kind of sun-proof, diaphragm-operated structural representation of treatment eye wrinkle-removing.
Wherein: the 1-adherent layer: the 2-gel layer; The 3-backing layer.
The specific embodiment
Below in conjunction with embodiment the present invention is further described.
Embodiment 1
Take the PVAC polyvinylalcohol-124 of 10g to be gel-type vehicle, add the water of 45g, make rubber cement, mix behind adding 15g silica gel, the 30g hyaluronic acid, obtain gel after the cooling; Above-mentioned gel is uniformly coated on the polyester adherent layer that silicone-treated crosses intensive drying; Cover on the backing film that contains the aluminumpolyethylene composite membrane, sealing is die-cut into suitable size, promptly gets diaphragm sun-proof, the treatment eye wrinkle-removing.
Embodiment 2
Take the PVAC polyvinylalcohol-124 of 15g to be gel-type vehicle, add 40g water, make rubber cement, mix behind adding 25g silica gel, the 20g hyaluronic acid, obtain gel after the cooling; Above-mentioned gel is uniformly coated on the polyester adherent layer that silicone-treated crosses intensive drying; Cover on the backing film that contains the aluminumpolyethylene composite membrane, sealing is die-cut into suitable size, promptly gets diaphragm sun-proof, the treatment eye wrinkle-removing.
Embodiment 3
Take 20g PVAC polyvinylalcohol-124 to be gel-type vehicle, add 35g water, make rubber cement, mix behind adding 20g silica gel, the 25g hyaluronic acid, obtain gel after the cooling; Above-mentioned gel is uniformly coated on the polyester adherent layer that silicone-treated crosses intensive drying; Cover on the backing film that contains the aluminumpolyethylene composite membrane, sealing is die-cut into suitable size, promptly gets diaphragm sun-proof, the treatment eye wrinkle-removing.
Embodiment 4
Take 20g PVAC polyvinylalcohol-124 to be gel-type vehicle, add 35g water, make rubber cement, mix behind adding 20g silica gel, the 25g hyaluronic acid, obtain gel after the cooling; Above-mentioned gel is uniformly coated on the polyester adherent layer that silicone-treated crosses intensive drying; Cover on the backing film that contains the aluminumpolyethylene composite membrane, scribble the individual character coloured picture on the backing film, be with three-dimensional figure ornament, sealing is die-cut into suitable size, promptly gets diaphragm sun-proof, the treatment eye wrinkle-removing.
Embodiment 5
Take the PVAC polyvinylalcohol-124 of 15g to be gel-type vehicle, add 40g water, make rubber cement, mix behind adding 25g silica gel, the 20g hyaluronic acid, obtain gel after the cooling; Above-mentioned gel is uniformly coated on the polyester adherent layer that silicone-treated crosses intensive drying; Cover on the backing film that contains the aluminumpolyethylene composite membrane, scribble the individual character coloured picture on the backing film, be with three-dimensional figure ornament, sealing is die-cut into suitable size, promptly gets diaphragm sun-proof, the treatment eye wrinkle-removing.
Embodiment 6
Take the PVAC polyvinylalcohol-124 of 10g to be gel-type vehicle, add the water of 45g, make rubber cement, mix behind adding 15g silica gel, the 30g hyaluronic acid, obtain gel after the cooling; Above-mentioned gel is uniformly coated on the polyester adherent layer that silicone-treated crosses intensive drying; Cover on the backing film that contains the aluminumpolyethylene composite membrane, scribble the individual character coloured picture on the backing film, be with three-dimensional figure ornament, sealing is die-cut into suitable size, promptly gets diaphragm sun-proof, the treatment eye wrinkle-removing.
Claims (3)
1, a kind of sun-proof, the treatment eye wrinkle-removing diaphragm, comprising:
A backing layer that is used for load active component;
The gel layer on the backing layer top that is laid in;
An adherent layer that covers on the gel layer,
Described gel layer contains PVAC polyvinylalcohol-124, silica gel, hyaluronic acid, water,
It is characterized in that: said components is by weight percentage:
PVAC polyvinylalcohol-124 10-20%
Hyaluronic acid 20-30%
Silica gel 15-25%
Water surplus.
2, according to claim 1 sun-proof, the treatment eye wrinkle-removing diaphragm, it is characterized in that: backing layer is for containing the aluminumpolyethylene composite membrane.
3, the diaphragm of sun-proof, treatment eye wrinkle-removing according to claim 1 is characterized in that: the adherent layer of being addressed for the surface through the polyester film of silicone oil release treatment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100302708A CN100341477C (en) | 2005-09-30 | 2005-09-30 | Film patch for shading sun and treating eye wrinkles |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100302708A CN100341477C (en) | 2005-09-30 | 2005-09-30 | Film patch for shading sun and treating eye wrinkles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1762322A CN1762322A (en) | 2006-04-26 |
| CN100341477C true CN100341477C (en) | 2007-10-10 |
Family
ID=36746787
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005100302708A Expired - Fee Related CN100341477C (en) | 2005-09-30 | 2005-09-30 | Film patch for shading sun and treating eye wrinkles |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100341477C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105267048A (en) * | 2014-06-27 | 2016-01-27 | 李和伟 | Novel mask fabric combination and application thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5876744A (en) * | 1994-08-01 | 1999-03-02 | Lifegroup S.P.A. | Highly bioadhesive and mucoadhesive compositions containing polyvinyl alcohol, polycarbophil and biopolymer for the treatment of skin conditions and as vehicles for active ingredients |
| CN2430885Y (en) * | 2000-04-13 | 2001-05-23 | 施明庆 | Face mask sticking cloth |
| CN2462923Y (en) * | 2001-02-27 | 2001-12-05 | 中国原子能科学研究院 | Hydrogel cosmetic skin-care patch |
| JP2004339139A (en) * | 2003-05-15 | 2004-12-02 | Kanebo Ltd | Skin cosmetic |
-
2005
- 2005-09-30 CN CNB2005100302708A patent/CN100341477C/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5876744A (en) * | 1994-08-01 | 1999-03-02 | Lifegroup S.P.A. | Highly bioadhesive and mucoadhesive compositions containing polyvinyl alcohol, polycarbophil and biopolymer for the treatment of skin conditions and as vehicles for active ingredients |
| CN2430885Y (en) * | 2000-04-13 | 2001-05-23 | 施明庆 | Face mask sticking cloth |
| CN2462923Y (en) * | 2001-02-27 | 2001-12-05 | 中国原子能科学研究院 | Hydrogel cosmetic skin-care patch |
| JP2004339139A (en) * | 2003-05-15 | 2004-12-02 | Kanebo Ltd | Skin cosmetic |
Non-Patent Citations (2)
| Title |
|---|
| 透明质酸在化妆品中的应用 李敬等，衡水学院学报，第7卷第1期 2005 * |
| 透明质酸的保湿特性及其在化妆品中的应用 李小迪，香料香精化妆品，第3期 1997 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1762322A (en) | 2006-04-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104587518B (en) | Hyaluronic acid dressing and preparation method thereof | |
| CN1221246C (en) | Compositions for prevention and alleviation of skin wrinkles | |
| CN107185031B (en) | A kind of biologically active medical dressing and preparation method thereof | |
| CN1130171C (en) | Stretchable hood utensil contg. stretchable adhesive matrix at least in moisture state | |
| CN108686255B (en) | Biological dressing for preventing scar formation and preparation method thereof | |
| CN1845716A (en) | Body care product containing porous silver particles | |
| CN1732897A (en) | Face-beautifying skin-caring lotion with leech extract and its preparation process | |
| CN106420381A (en) | Novel applications of artemisinin ingredients or composition of artemisinin ingredients in skin care | |
| CN1142761C (en) | Clean sticking sheet for displaying skin condition | |
| KR101895038B1 (en) | Dissolvable film comprising spicule and use thereof | |
| KR102613845B1 (en) | Cosmetic composition for improvement of skin derived from natural products | |
| CN107550753A (en) | A kind of composition and preparation method thereof with skin repair, anti-senescence function | |
| CN113576975A (en) | Easily-absorbed anti-aging composition and preparation method and application thereof | |
| EP2651511B1 (en) | Non-therapeutic method for treating non-acneic oily skin | |
| CN106102513B (en) | Skin masking material | |
| CN1301745C (en) | Chinese medicinal liquid for treating alopecia and its production method | |
| CN100341477C (en) | Film patch for shading sun and treating eye wrinkles | |
| CN108852900B (en) | Thirteen-peptide-containing antibacterial mask and preparation method thereof | |
| CN109820807A (en) | A kind of moisturizing restorative facial cream and preparation method thereof | |
| CN100341529C (en) | Combination of Tibet medicine of containing salt and possessing medicinal effect health care, and preparation metohd | |
| CN104473798A (en) | Pseudo-ginseng skin toner and preparation method thereof | |
| CN110664660A (en) | Scar-resistant composition and preparation method thereof | |
| CN1839791A (en) | Camellia cosmetics | |
| CN100379447C (en) | Composition containing PVA-124 and its application | |
| CN1244319C (en) | Biomimetic cosmetic for courishing skin |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20071010 Termination date: 20120930 |