CN100337676C

CN100337676C - Erythromelalgia treating medicine

Info

Publication number: CN100337676C
Application number: CNB2005100505789A
Authority: CN
Inventors: 孙振华
Original assignee: Individual
Current assignee: Individual
Priority date: 2005-07-05
Filing date: 2005-07-05
Publication date: 2007-09-19
Anticipated expiration: 2025-07-05
Also published as: CN1720985A

Abstract

The present invention discloses erythromelalgia treating medicine which is a medicament made of seven kinds of Chinese medicine comprising antelope bones, buffalo horns, mulberry twigs, capillary wormwoods, rhizoma, Job's-tears seeds and caulis lonicerae, and each kind of Chinese medicine comprises the distribution ratio of parts by weight: 15 to 22 parts of the antelope bones, 20 to 40 parts of the buffalo horns, 20 to 40 parts of the mulberry twigs, 20 to 40 parts of the capillary wormwoods, 20 to 40 parts of the rhizoma, 20 to 40 parts of the Job's-tears seeds and 15 to 22 parts of caulis lonicerae. The present invention thinks that erythromelalgia is mainly caused by liver dysfunction, stagnation of qi activities and downward flow of damp heat on the basis of the traditional experiences through combining the pathological mechanism of the modern Chinese medicine. Aiming at the characteristics of the erythromelalgia, the present invention carries out reasonable dispensation for the Chinese medicine with cheap price and safety through clinical use, and then each kind of Chinese medicine can be cooperated with each other to together exert the main efficiency of fire-purging dampness removal and channel activation to stop pain. The present invention has good heat clearing, channel activating, pain alleviating and dampness removing efficiency, and is especially suitable for treating the erythromelalgia.

Description

A kind of medicine for the treatment of erythromelalgia

Technical field:

The present invention relates to a kind of medicine for the treatment of erythromelalgia, belong to the technical field of pharmaceuticals for the treatment of erythromelalgia.

Background technology:

Erythromelalgia is a kind of vasomotor disturbance disease.Can betide any age and sex, this disease is sent out in foot well, is hand secondly, and weight person can involve whole limbs.Mostly be the bilateral outbreak, also can be one-sided property.This disease shows as paroxysmal affected part vasodilation hyperemia more, skin rubefaction heating, and temperature increases 2～3 ℃ than normally, and it is obvious to perspire, and conscious scorching hot severe pain is shown effect at every turn and was not waited to a few hours in sustainable several minutes.The medicine of this disease of treatment is less at present, mostly is Western medicine greatly, though these Western medicine have certain curative effect, it exists the phenomenon of toxic and side effects also relatively more serious; And Western medicine also exists treatment long, the higher shortcoming of the medical expense course of treatment.Many hospitals often should disease treat as peripheral neuritis, and the medication effect that it adopted is also not ideal.Therefore, the therapeutic effect of the medicine of existing treatment erythromelalgia still can not be satisfactory.

Summary of the invention:

The objective of the invention is: provide a kind of therapeutic effect better, have no side effect, the medicine of treatment erythromelalgia that medical expense is lower, to overcome the deficiencies in the prior art.

The present invention is achieved in that the medicament that this medicine is made by Os Caprae Saigae Tataricae, Cornu Bubali, Ramulus Mori, capillary wormwood, Rhizoma Smilacis Glabrae, Semen Coicis, Flos Lonicerae TENGQI (sic) flavor Chinese medicine, and each Chinese medicine proportioning by weight of distinguishing the flavor of is: 15～22 parts of Os Caprae Saigae Tataricaes, 20～40 parts of Cornu Bubalis, 20～40 parts of Ramulus Moris, 20～40 parts of capillary wormwoods, 20～40 parts of Rhizoma Smilacis Glabraes, 20～40 parts of Semen Coiciss, 15～22 parts of Caulis Lonicerae.

Each Chinese medicine optimum ratio scope by weight of distinguishing the flavor of is: 17～21 parts of Os Caprae Saigae Tataricaes, 25～35 parts of Cornu Bubalis, 25～35 parts of Ramulus Moris, 25～35 parts of capillary wormwoods, 25～35 parts of Rhizoma Smilacis Glabraes, 25～35 parts of Semen Coiciss, 17～21 parts of Caulis Lonicerae.

Each Chinese medicine best proportioning by weight of distinguishing the flavor of is: 20 parts of Os Caprae Saigae Tataricaes, 32 parts of Cornu Bubalis, 32 parts of Ramulus Moris, 32 parts of capillary wormwoods, 32 parts of Rhizoma Smilacis Glabraes, 32 parts of Semen Coiciss, 20 parts of Caulis Lonicerae.

Best medicament of the present invention is an oral liquid formulation.

In prescription of the present invention: Os Caprae Saigae Tataricae, nature and flavor are salty, cold, return liver, heart channel, have suppressing the hyperactive liver to relieve the wind syndrome, liver heat removing and eyesight improving, the effect of the blood detoxifcation of loosing, be usually used in that hyperpyrexia infantile convulsion, coma convulsion are fainted, treatment of diseases such as dizzy, conjunctival congestion cataracta is gone mad, had a headache in eclamposia tic, epilepsy, maculae caused by violent heat pathogen, carbuncle sore tumefacting virus;

Cornu Bubali, the nature and flavor hardship is salty, cold, and GUIXIN, liver, stomach warp have the function of Hot detoxifcation clearly, Cool blood, are usually used in treating diseases such as Zhi Wind Hot Head pain, high Hot stupor, macule, haematemesis, Xiao Jing Wind, Hou Swollen pain, Yi Brain clinically;

Ramulus Mori, property mildly bitter flavor, flat is returned Liver Channel, has the effect in wind-damp dispelling, sharp joint, is usually used in takeing on the treatment of diseases such as arm, joint aches numbness;

Capillary wormwood, is slightly cold at nature and flavor hardship, suffering, returns spleen, stomach, liver, gallbladder meridian, has the effect of clearing away damp-heat, is mainly used in the treatment of jaundice eliminating subcutaneous ulcer clinically;

Rhizoma Smilacis Glabrae, nature and flavor are sweet, light, flat, return liver, stomach warp, have the effect of dehumidifying, detoxifcation, easing joint movement, are usually used in the treatment of diseases such as limbs contracture, bones and muscles pain due to damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, scrofula, scabies, syphilis and the mercurialism;

Semen Coicis, is slightly cold at the property slightly sweet flavor, but promoting diuresis to eliminate damp pathogen, invigorating the spleen to arrest diarrhea, antiinflammatory toxin expelling;

Caulis Lonicerae, nature and flavor are sweet, cold, " acrid in the mouth ", GUIXIN, lung meridian have the effect of heat clearing away, detoxifcation, collateral dredging, are usually used in treatment of diseases such as epidemic febrile disease heating, toxic-heat and blood stasis, infectious hepatitis, carbuncle sore tumefacting virus, bones and muscles pain.

The present invention is according to traditional experience, and in conjunction with the pathomechanism of modern Chinese medicine, thinks that erythromelalgia mainly is by due to the liver failing to maintain the normal flow of QI, the strongly fragrant resistance of mechanism of qi, the damp invasion of lower energizer.Treatment should be based on eliminating pathogen in the liver through excess-fire, the wet collateral dredging of diuretic.Therefore the present invention is directed to the characteristics of erythromelalgia, through long-term experiment, comparison and research, with above-mentioned commonly used inexpensive and after the safer Chinese medicine of clinical use proof carries out rational formula, make the Chinese medicine of respectively distinguishing the flavor of to coordinate the effect of common performance mutually based on pathogenic fire purging dehumidifying, removing obstruction in the collateral to relieve pain.Through clinical verification, the present invention has the effect of heat clearing away preferably, collateral dredging, pain relieving, dehumidifying, is particularly suitable for treating erythromelalgia.And when treating erythromelalgia, compare with existing medicine with the present invention, the present invention also have therapeutic effect better, short treating period, be difficult for recurring, have no side effect, advantage that medical expense is lower.

The specific embodiment:

Embodiments of the invention: get Os Caprae Saigae Tataricae 20 gram and Cornu Bubali 32 and restrain and add 500 ml waters and be decocted first 20～50 minutes, and then get Ramulus Mori 32 gram, capillary wormwood 32 grams, Rhizoma Smilacis Glabrae 32 grams, Semen Coicis 32 grams, Caulis Lonicerae 20 grams and put into 1000 ml waters and soak and pour the mixed liquor that the decocting liquid that contains Os Caprae Saigae Tataricae and Cornu Bubali must contain this seven flavors Chinese medicine after 30～60 minutes together into, then it is contained and decocted again 20～50 minutes after seven mixed liquors of distinguishing the flavor of Chinese medicines are boiled, medicinal residues are filtered out, get its medicinal liquid and can make oral liquid formulations of the present invention.Oral liquid formulations of the present invention also can be made by other conventional oral liquid processing technology; The present invention also can be made as said regular dosage form on the pharmaceutics, as is made into dosage forms such as said tablet, pill, capsule, powder on the pharmaceutics, and these dosage forms can be made by the traditional method of corresponding dosage form.

The instructions about how to take medicine of oral liquid formulations of the present invention are: every day 3 times, each 40～60 milliliters, general 3～6 days is a course of treatment.

Be the clinical observation example that adopts the present invention to treat the erythromelalgia patient below, so that curative effect of the present invention is further described:

Case 1: the patient man, 40 years old, scorching hot twinge three wheat harvesting periods of its left foot internal malleolus and sole of the foot toe, on inspection, this patient's blood pressure, cardiopulmonary are normal, the liver spleen do not lay one's hand on and, quadriceps reflex is normal, left sufficient internal malleolus and sufficient sole of the foot skin anxiety, scorching hot, flushing, swelling slightly; Through laboratory examination, routine blood test is normal.According to patient's reflection, this disease is not seen effectively by the peripheral neuritis treatment through examination in hospital January.

The patient checks after three days through taking the present invention, and its pain obviously alleviates, but brings out pain again with the warm water foot bath before sleeping, and more preceding is light.

The patient continue again to take the present invention after three days symptom all disappear.Follow up a case by regular visits to not recurrence again in a year.

Case 2: patient woman, 47 years old, in two sufficient six weeks of pain of patient, its pain is the bright sample paroxysmal pain of fire, and particularly night, pain was obvious, the pain increased with the hot water foot bath, dash then pain in foot with cold water and alleviate rapidly, but pain again after a period of time, two insteps are scorching hot rubescent or blue during pain,, once obeyed the antipyretic-antalgic sheet and failed to get effect for very with the left side.On inspection, this patient's blood pressure is normal, cardiopulmonary (-), liver spleen do not lay one's hand on and, quadriceps reflex is normal, the scorching hot redness of two skin of dorsum of foot; Through laboratory examination, routine blood test is normal.

The patient checks after six days through taking the present invention, and its pain is controlled, continue again to take the present invention after three days symptom all disappear.Follow up a case by regular visits to not recurrence again in a year.

Above-mentioned patient any untoward reaction do not occur taking during the present invention treats.

Claims

1, a kind of medicine for the treatment of erythromelalgia, it is characterized in that: the medicament that this medicine is made by Os Caprae Saigae Tataricae, Cornu Bubali, Ramulus Mori, capillary wormwood, Rhizoma Smilacis Glabrae, Semen Coicis, Flos Lonicerae TENGQI (sic) flavor Chinese medicine, each Chinese medicine proportioning by weight of distinguishing the flavor of is: 15～22 parts of Os Caprae Saigae Tataricaes, 20～40 parts of Cornu Bubalis, 20～40 parts of Ramulus Moris, 20～40 parts of capillary wormwoods, 20～40 parts of Rhizoma Smilacis Glabraes, 20～40 parts of Semen Coiciss, 15～22 parts of Caulis Lonicerae.

2, the medicine of treatment erythromelalgia according to claim 1 is characterized in that: each Chinese medicine optimum ratio scope by weight of distinguishing the flavor of is: 17～21 parts of Os Caprae Saigae Tataricaes, 25～35 parts of Cornu Bubalis, 25～35 parts of Ramulus Moris, 25～35 parts of capillary wormwoods, 25～35 parts of Rhizoma Smilacis Glabraes, 25～35 parts of Semen Coiciss, 17～21 parts of Caulis Lonicerae.

3, the medicine of treatment erythromelalgia according to claim 1 is characterized in that: each Chinese medicine best proportioning by weight of distinguishing the flavor of is: 20 parts of Os Caprae Saigae Tataricaes, 32 parts of Cornu Bubalis, 32 parts of Ramulus Moris, 32 parts of capillary wormwoods, 32 parts of Rhizoma Smilacis Glabraes, 32 parts of Semen Coiciss, 20 parts of Caulis Lonicerae.

4, the medicine of treatment erythromelalgia according to claim 1 is characterized in that: said medicament is an oral liquid formulation.