CL2016002946A1 - Aparato para sellar una punción vascular que comprende un sellante que tiene copolímeros de quitosano y polietilenglicol; y método para fabricar dicho aparato. - Google Patents

Aparato para sellar una punción vascular que comprende un sellante que tiene copolímeros de quitosano y polietilenglicol; y método para fabricar dicho aparato.

Info

Publication number
CL2016002946A1
CL2016002946A1 CL2016002946A CL2016002946A CL2016002946A1 CL 2016002946 A1 CL2016002946 A1 CL 2016002946A1 CL 2016002946 A CL2016002946 A CL 2016002946A CL 2016002946 A CL2016002946 A CL 2016002946A CL 2016002946 A1 CL2016002946 A1 CL 2016002946A1
Authority
CL
Chile
Prior art keywords
section
sealant
appliance
manufacturing
vascular puncture
Prior art date
Application number
CL2016002946A
Other languages
English (en)
Inventor
Andreas Mylonakis
Florencia Lim
Original Assignee
Access Closure Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Access Closure Inc filed Critical Access Closure Inc
Publication of CL2016002946A1 publication Critical patent/CL2016002946A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0031—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/145—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A61B2017/00623—Introducing or retrieving devices therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00646—Type of implements
    • A61B2017/0065—Type of implements the implement being an adhesive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Materials For Medical Uses (AREA)
  • Surgical Instruments (AREA)
  • Medicinal Preparation (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Sealing Material Composition (AREA)

Abstract

EL PROBLEMA TÉCNICO PLANTEADO POR LA SOLICITUD SE REFIERE A UN APARATO PARA SELLAR UNA PUNCIÓN VASCULAR, Y A UN APARATO PARA FABRICAR DICHO APARATO. LA SOLUCIÓN AL PROBLEMA TÉCNICO PLANTEADO SE REFIERE A PROPORCIONAR UN APARATO PARA SELLAR UNA PUNCIÓN VASCULAR QUE COMPRENDE UN SELLANTE QUE TIENE UNA PRIMERA SECCIÓN FORMADA POR UN HIDROGEL QUE COMPRENDE COPOLÍMEROS DE QUITOSANO Y POLIETILENGLICOL, EN DONDE EN LA EXPOSICIÓN A UN FLUIDO FISIOLÓGICO ACUOSO, EL HIDROGEL SE EXPANDE Y SELLA LA PUNCIÓN A TRAVÉS DEL TEJIDO, DONDE ESTA PRIMERA SECCIÓN INCLUYE UN EXTREMO PROXIMAL Y UN EXTREMO DISTAL. EL SELLADOR COMPRENDE ADEMÁS UNA SEGUNDA SECCIÓN QUE SE EXTIENDE DESDE EL EXTREMO DISTAL DE LA PRIMERA SECCIÓN, QUE CONTIENEN UNA MEZCLA DE PEG NO RETICULADO Y QUITOSANO, DONDE LA PRIMERA Y SEGUNDA SECCIÓN TIENEN UNA SECCIÓN TRANSVERSAL EXTERIOR. LA SOLICITUD SE REFIERE ADEMÁS A PROPORCIONAR UN MÉTODO PARA FABRICAR DICHO APARATO.
CL2016002946A 2014-05-29 2016-11-18 Aparato para sellar una punción vascular que comprende un sellante que tiene copolímeros de quitosano y polietilenglicol; y método para fabricar dicho aparato. CL2016002946A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462004806P 2014-05-29 2014-05-29

Publications (1)

Publication Number Publication Date
CL2016002946A1 true CL2016002946A1 (es) 2017-04-17

Family

ID=53396584

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2016002946A CL2016002946A1 (es) 2014-05-29 2016-11-18 Aparato para sellar una punción vascular que comprende un sellante que tiene copolímeros de quitosano y polietilenglicol; y método para fabricar dicho aparato.

Country Status (14)

Country Link
US (4) US9861348B2 (es)
EP (2) EP3148602B1 (es)
JP (4) JP6681343B2 (es)
KR (3) KR102454789B1 (es)
CN (2) CN111643129B (es)
AU (4) AU2015266837B2 (es)
BR (2) BR112016027378B1 (es)
CA (1) CA2949842A1 (es)
CL (1) CL2016002946A1 (es)
IL (1) IL249096B2 (es)
MX (2) MX2020002757A (es)
NZ (1) NZ756435A (es)
RU (1) RU2696139C2 (es)
WO (1) WO2015184160A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA40946A (fr) 2014-11-14 2017-09-19 Access Closure Inc Appareil et procédés permettant de rendre étanche une ponction vasculaire
USD865166S1 (en) 2015-11-13 2019-10-29 Access Closure, Inc. Sheath adapter
USD843573S1 (en) 2015-11-13 2019-03-19 Access Closure, Inc. Vascular closure apparatus
USD847988S1 (en) 2015-11-13 2019-05-07 Access Closure, Inc. Handle grip
KR101989054B1 (ko) * 2017-11-28 2019-06-13 (주)다림티센 지혈용 조성물 및 이를 포함하는 용기
EP4385426A3 (en) * 2018-01-29 2024-07-24 Access Closure, Inc. Apparatus for sealing a vascular puncture
CN110193091A (zh) * 2018-02-27 2019-09-03 华东理工大学 可注射蛋白/聚乙二醇基水凝胶材料及其制备方法和应用
EP3766436A4 (en) * 2018-03-29 2021-03-31 TERUMO Kabushiki Kaisha EMBOLICATE MATERIAL AND ITS MANUFACTURING PROCESS
JP7241095B2 (ja) * 2018-05-15 2023-03-16 ボストン サイエンティフィック サイムド，インコーポレイテッド 帯電したポリマーコーティングを備えた閉塞性医療装置
CN108784772B (zh) * 2018-07-30 2024-04-16 中国人民解放军总医院第四医学中心 一种伸缩式止血气囊
CN110478528B (zh) * 2019-08-14 2021-12-17 暨南大学 一种新型的促组织修复材料的制备方法及其应用
EP4135593A4 (en) * 2020-04-14 2024-05-01 Deinde Medical Corp. CLOSURE DEVICES AND METHODS FOR CLOSING BIOLOGICAL TISSUE MEMBRANES
CN111603604B (zh) * 2020-05-26 2021-11-30 山东朱氏药业集团有限公司 一种聚对二氧杂环己酮高强度高抗菌缝合线及制备方法
CN114481392A (zh) * 2022-01-06 2022-05-13 西安工程大学 一种纳米纤维包覆纱及其制备方法、纳米纤维包覆纱股线及其应用
IL314817A (en) * 2022-02-10 2024-10-01 Avana Health Inc Apparatus for treating uterine bleeding and method for use
WO2024054482A1 (en) * 2022-09-06 2024-03-14 University Of South Florida Composition for photochemical tissue bonding
CN118000809A (zh) * 2022-11-10 2024-05-10 深圳市先健纬康科技有限公司 一种穿刺孔闭合装置

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4394373A (en) 1981-04-06 1983-07-19 Malette William Graham Method of achieving hemostasis
US4890612A (en) * 1987-02-17 1990-01-02 Kensey Nash Corporation Device for sealing percutaneous puncture in a vessel
US5264214A (en) * 1988-11-21 1993-11-23 Collagen Corporation Composition for bone repair
US5334216A (en) 1992-12-10 1994-08-02 Howmedica Inc. Hemostatic plug
US5814567A (en) 1996-06-14 1998-09-29 Kimberly-Clark Worldwide, Inc. Durable hydrophilic coating for a porous hydrophobic substrate
US7351421B2 (en) * 1996-11-05 2008-04-01 Hsing-Wen Sung Drug-eluting stent having collagen drug carrier chemically treated with genipin
US7790192B2 (en) 1998-08-14 2010-09-07 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
US6703047B2 (en) 2001-02-02 2004-03-09 Incept Llc Dehydrated hydrogel precursor-based, tissue adherent compositions and methods of use
US6605294B2 (en) 1998-08-14 2003-08-12 Incept Llc Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels
KR100698559B1 (ko) * 1999-06-11 2007-03-21 넥타르 테라퓨틱스 에이엘, 코포레이션 키토산 및 폴리(에틸렌 글리콜) 또는 관련 폴리머로부터유래되는 하이드로겔
US6569185B2 (en) * 2001-02-15 2003-05-27 Scimed Life Systems Inc Continuous infusion technique for arterial sealing
US7700819B2 (en) * 2001-02-16 2010-04-20 Kci Licensing, Inc. Biocompatible wound dressing
US8430934B2 (en) * 2002-03-01 2013-04-30 Regents Of The University Of Minnesota Vascular occlusion device
US7166133B2 (en) 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
US7998188B2 (en) * 2003-04-28 2011-08-16 Kips Bay Medical, Inc. Compliant blood vessel graft
US7331979B2 (en) 2003-06-04 2008-02-19 Access Closure, Inc. Apparatus and methods for sealing a vascular puncture
EP1631262A4 (en) 2003-06-12 2010-05-05 Boston Scient Ltd An Irish Co IMPROVED SYSTEM AND METHOD FOR FACILITATING HEMOSTASE USING AN ABSORBABLE SPONGE
WO2005002510A2 (en) * 2003-06-16 2005-01-13 Loma Linda University Medical Center Deployable multifunctional hemostatic agent
DE602004031953D1 (es) * 2003-08-14 2011-05-05 Univ Loma Linda Med
US20050175659A1 (en) 2004-02-09 2005-08-11 Macomber Laurel R. Collagen device and method of preparing the same
US7806856B2 (en) 2005-04-22 2010-10-05 Accessclosure, Inc. Apparatus and method for temporary hemostasis
JP2007001963A (ja) * 2005-06-21 2007-01-11 Koji Kibune 吸水性の高いキトサンスポンジの製造方法
US8795709B2 (en) 2006-03-29 2014-08-05 Incept Llc Superabsorbent, freeze dried hydrogels for medical applications
TWI436793B (zh) 2006-08-02 2014-05-11 Baxter Int 快速作用之乾密封膠及其使用和製造方法
EP2077765A2 (en) 2006-09-13 2009-07-15 Accessclosure, Inc. Apparatus for sealing a vascular puncture
US7993367B2 (en) 2007-09-28 2011-08-09 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
CA2703103C (en) 2007-10-30 2017-05-09 Baxter Healthcare S.A. Use of a regenerative biofunctional collagen biomatrix for treating visceral or parietal defects
JP2011502582A (ja) 2007-11-02 2011-01-27 インセプト，エルエルシー 血管穿刺を塞ぐ装置および方法
US7868123B2 (en) 2007-11-19 2011-01-11 Ethicon, Inc. Derivatized tertiary amines and uses thereof
US8029533B2 (en) 2008-04-04 2011-10-04 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
US8530632B2 (en) * 2008-04-24 2013-09-10 Medtronic Xomed, Inc. Chitosan-containing protective composition
EP3821817A3 (en) 2008-11-12 2021-11-03 Access Closure, Inc. Apparatus for sealing a vascular puncture
CA2750242C (en) 2009-02-12 2018-05-22 Incept, Llc Drug delivery through hydrogel plugs
US8292918B2 (en) 2009-02-20 2012-10-23 Boston Scientific Scimed, Inc. Composite plug for arteriotomy closure and method of use
US8529598B2 (en) * 2009-02-20 2013-09-10 Boston Scientific Scimed, Inc. Tissue puncture closure device
EP2427233B1 (en) 2009-05-04 2016-12-21 Incept Llc Biomaterials for track and puncture closure
CA2780294C (en) * 2009-11-09 2018-01-16 Spotlight Technology Partners Llc Polysaccharide based hydrogels
CA2780274C (en) * 2009-11-09 2018-06-26 Spotlight Technology Partners Llc Fragmented hydrogels
CA2824964C (en) * 2011-01-19 2019-01-08 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
US20150328062A9 (en) * 2011-11-10 2015-11-19 Covidien Lp Hydrophilic medical devices
KR102448413B1 (ko) 2012-03-23 2022-09-27 액세스클로저, 아이엔씨. 혈관 천자를 밀봉하기 위한 장치
EP2858576A2 (en) * 2012-06-11 2015-04-15 E- Pacing, Inc. Vasculature closure devices and methods

Also Published As

Publication number Publication date
CN106456846A (zh) 2017-02-22
EP3148602A1 (en) 2017-04-05
AU2015266837B2 (en) 2019-04-04
AU2019204615B2 (en) 2021-04-08
CA2949842A1 (en) 2015-12-03
KR102454789B1 (ko) 2022-10-17
JP6681343B2 (ja) 2020-04-15
KR20220144883A (ko) 2022-10-27
US20180168562A1 (en) 2018-06-21
KR102703232B1 (ko) 2024-09-06
JP2023134589A (ja) 2023-09-27
KR20170033812A (ko) 2017-03-27
JP2017517316A (ja) 2017-06-29
US20210030405A1 (en) 2021-02-04
EP4032563A1 (en) 2022-07-27
EP3148602B1 (en) 2021-12-22
RU2019123291A (ru) 2020-04-28
RU2696139C2 (ru) 2019-07-31
AU2015266837A1 (en) 2016-12-22
MX2020002757A (es) 2022-03-30
CN111643129A (zh) 2020-09-11
AU2023237172A1 (en) 2023-10-19
BR112016027378B1 (pt) 2021-03-23
AU2021204805A1 (en) 2021-08-05
US20180168563A1 (en) 2018-06-21
NZ727124A (en) 2020-10-30
US11751857B2 (en) 2023-09-12
KR20240135881A (ko) 2024-09-12
IL249096A0 (en) 2017-01-31
BR122019024398B1 (pt) 2021-08-17
JP2021151492A (ja) 2021-09-30
WO2015184160A1 (en) 2015-12-03
US20150342581A1 (en) 2015-12-03
MX2016015287A (es) 2017-05-09
AU2019204615A1 (en) 2019-07-18
JP6890191B2 (ja) 2021-06-18
JP2020089743A (ja) 2020-06-11
US9861348B2 (en) 2018-01-09
NZ756435A (en) 2022-12-23
IL249096B1 (en) 2023-04-01
CN111643129B (zh) 2024-06-11
CN106456846B (zh) 2020-05-15
BR112016027378A2 (pt) 2018-06-26
RU2016147920A3 (es) 2018-11-14
IL249096B2 (en) 2023-08-01
RU2016147920A (ru) 2018-07-03

Similar Documents

Publication Publication Date Title
CL2016002946A1 (es) Aparato para sellar una punción vascular que comprende un sellante que tiene copolímeros de quitosano y polietilenglicol; y método para fabricar dicho aparato.
DK3558168T3 (da) Hjerteklaptætningsindretninger
IL268071A (en) blood pump
IL273154A (en) blood pump
PE20170167A1 (es) Conjunto de cable de fibra optica para terminacion de un cable de fibra optica y metodos de fabricacion de los mismos
ES2723425T3 (es) Dispositivos de anastomosis
EP3321299A4 (en) CARBODIIMIDE-BASED AQUEOUS RESIN NETWORK
EP3272790A4 (en) Thermoplastic elastomer composition, use thereof, method for producing same, ethylene/ -olefin/unconjugated polyene copolymer and use thereof
DK3513809T3 (da) Medicinsk sammensætning, som omfatter tivozanib
DK3219268T3 (da) Radial tætningsenhed, endetætning og trokar
SG10202008596SA (en) Versatile, flexible and biocompatible elastomeric microtubes
EP3338839A4 (en) SYRINGE ASSEMBLY, PRE-FILLED SYRINGE, SEALING CAP FOR EXTERNAL TUBE AND PACKAGING FOR SYRINGE ASSEMBLY
EP3495016A4 (en) VALVE NEEDLE AND REMAINING VALVE NEEDLE ASSEMBLY
SG11201707283SA (en) Resin composition, adhesive agent, and sealing agent
EP3263042A4 (en) Endoscope puncture needle
BR112016019510A2 (pt) esterilização e filtração de composições de peptídeos
PL3064542T3 (pl) Biodegradowalna termoplastyczna kompozycja polimerowa, sposób jej wytwarzania oraz zastosowanie
SI3331583T1 (sl) Medicinski implantat na osnovi nanoceluloze
FR3040166B1 (fr) Conditionnement souple de dechets notamment d'amiante, a double enveloppe, aux proprietes ameliorees.
BR112017004745A2 (pt) adição a um aplicador médico
DK3149100T3 (da) Hydrofobe polyoler til forseglingsanvendelser
EP3235521A4 (en) SUPER ABSORBENT RESIN FOR THE ABSORPTION OF BLOOD OR HIGH VISCOSITY LIQUID AND METHOD FOR THE PRODUCTION THEREOF
GB201717644D0 (en) Sterile syringe
DK3503934T3 (da) Fremgangsmåder til selektiv modificering af medicinske slangers fleksibilitet
IL261800A (en) Dropper and hose for drip irrigation