CL2016002918A1 - Compuestos derivados de quinazolina-4(3h)-ona-n-hidroxi-2-metil-2-metilsulfonil-butanamida; composicion farmaceutica; actividad antibacteriana gram-negativo. - Google Patents

Compuestos derivados de quinazolina-4(3h)-ona-n-hidroxi-2-metil-2-metilsulfonil-butanamida; composicion farmaceutica; actividad antibacteriana gram-negativo.

Info

Publication number
CL2016002918A1
CL2016002918A1 CL2016002918A CL2016002918A CL2016002918A1 CL 2016002918 A1 CL2016002918 A1 CL 2016002918A1 CL 2016002918 A CL2016002918 A CL 2016002918A CL 2016002918 A CL2016002918 A CL 2016002918A CL 2016002918 A1 CL2016002918 A1 CL 2016002918A1
Authority
CL
Chile
Prior art keywords
quinazoline
methylsulfonyl
hydroxy
methyl
butanamide
Prior art date
Application number
CL2016002918A
Other languages
English (en)
Inventor
Azely Mirre
Jean-Phillippe Surivet
Gaëlle Chapoux
Jean-Christophe Gauvin
Original Assignee
Idorsia Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idorsia Pharmaceuticals Ltd filed Critical Idorsia Pharmaceuticals Ltd
Publication of CL2016002918A1 publication Critical patent/CL2016002918A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Compuestos derivados de compuestos derivados quinazolina-4(3H)-ona-N-hidroxi-2-metil-2-metilsulfonil-butanamida con actividad antibacteriana Gram negativo
CL2016002918A 2014-05-16 2016-11-16 Compuestos derivados de quinazolina-4(3h)-ona-n-hidroxi-2-metil-2-metilsulfonil-butanamida; composicion farmaceutica; actividad antibacteriana gram-negativo. CL2016002918A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14168718 2014-05-16

Publications (1)

Publication Number Publication Date
CL2016002918A1 true CL2016002918A1 (es) 2017-04-07

Family

ID=50731968

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2016002918A CL2016002918A1 (es) 2014-05-16 2016-11-16 Compuestos derivados de quinazolina-4(3h)-ona-n-hidroxi-2-metil-2-metilsulfonil-butanamida; composicion farmaceutica; actividad antibacteriana gram-negativo.

Country Status (19)

Country Link
US (1) US9796686B2 (es)
EP (1) EP3143007B1 (es)
JP (1) JP2017515906A (es)
KR (1) KR20170005105A (es)
CN (1) CN106458931A (es)
AR (1) AR100428A1 (es)
AU (1) AU2015261540A1 (es)
BR (1) BR112016026787A8 (es)
CA (1) CA2948077A1 (es)
CL (1) CL2016002918A1 (es)
EA (1) EA201692305A1 (es)
ES (1) ES2687040T3 (es)
IL (1) IL248922A0 (es)
MX (1) MX2016014989A (es)
PH (1) PH12016502253A1 (es)
SG (1) SG11201609286VA (es)
TW (1) TW201625559A (es)
WO (1) WO2015173329A1 (es)
ZA (1) ZA201608680B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR097617A1 (es) 2013-09-13 2016-04-06 Actelion Pharmaceuticals Ltd Derivados antibacterianos del 2h-indazol
EP3083567B1 (en) 2013-12-19 2018-03-07 Idorsia Pharmaceuticals Ltd Antibacterial 1h-indazole and 1h-indole derivatives
AR099612A1 (es) 2014-03-04 2016-08-03 Actelion Pharmaceuticals Ltd Derivados antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona
AR105646A1 (es) * 2015-08-11 2017-10-25 Actelion Pharmaceuticals Ltd Agentes antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituida
EA201890600A1 (ru) * 2015-08-28 2018-09-28 Идорсиа Фармасьютиклз Лтд Антибактериальные аннелированные производные пирролидин-2-она
AR105889A1 (es) 2015-09-03 2017-11-22 Actelion Pharmaceuticals Ltd Compuestos antibacterianos 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituidos
CA3007653A1 (en) * 2015-12-08 2017-06-15 Glaxosmithkline Intellectual Property Development Limited Substituted benzazinones as antibacterial compounds
KR102401841B1 (ko) 2016-04-01 2022-05-25 리커리엄 아이피 홀딩스, 엘엘씨 에스트로겐 수용체 조절제
CA3037118C (en) * 2016-09-28 2021-12-14 Dong-A St Co., Ltd. Tetrahydropyridine derivatives and their use as antibacterial agents
AU2020326691A1 (en) 2019-08-06 2022-03-03 Recurium Ip Holdings, Llc Estrogen receptor modulators for treating mutants

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JP2001513771A (ja) 1997-02-27 2001-09-04 アメリカン・サイアナミド・カンパニー マトリクス金属プロテイナーゼ阻害薬としてのｎ−ヒドロキシ−２−（アルキル、アリール、またはヘテロアリールスルファニル、スルフィニルまたはスルホニル）−３−置換アルキル、アリールまたはヘテロアリールアミド
PT2275102E (pt) 2002-03-13 2015-10-27 Array Biopharma Inc Derivados de benzimidazole alquilado n3 como inibidores de mek
CN101765585B (zh) * 2007-06-12 2017-03-15 尔察祯有限公司 抗菌剂
JP5455913B2 (ja) 2008-08-27 2014-03-26 大正製薬株式会社 ナフチリジン−ｎ−オキシドを有する新規ヒドロキサム酸誘導体
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AR097617A1 (es) 2013-09-13 2016-04-06 Actelion Pharmaceuticals Ltd Derivados antibacterianos del 2h-indazol
EP3083567B1 (en) 2013-12-19 2018-03-07 Idorsia Pharmaceuticals Ltd Antibacterial 1h-indazole and 1h-indole derivatives
AR099612A1 (es) 2014-03-04 2016-08-03 Actelion Pharmaceuticals Ltd Derivados antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona

Also Published As

Publication number Publication date
JP2017515906A (ja) 2017-06-15
ZA201608680B (en) 2018-11-28
EP3143007A1 (en) 2017-03-22
KR20170005105A (ko) 2017-01-11
CN106458931A (zh) 2017-02-22
US20170081292A1 (en) 2017-03-23
US9796686B2 (en) 2017-10-24
AU2015261540A1 (en) 2017-01-12
EP3143007B1 (en) 2018-07-11
EA201692305A1 (ru) 2017-05-31
ES2687040T3 (es) 2018-10-23
TW201625559A (zh) 2016-07-16
AR100428A1 (es) 2016-10-05
SG11201609286VA (en) 2016-12-29
IL248922A0 (en) 2017-01-31
MX2016014989A (es) 2017-03-31
WO2015173329A1 (en) 2015-11-19
BR112016026787A2 (es) 2017-08-15
CA2948077A1 (en) 2015-11-19
PH12016502253A1 (en) 2017-01-16
BR112016026787A8 (pt) 2017-12-26

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