CL2016002413A1 - Anticuerpos de hemaglutinina contra el virus de la influenza b y métodos de uso - Google Patents

Anticuerpos de hemaglutinina contra el virus de la influenza b y métodos de uso

Info

Publication number
CL2016002413A1
CL2016002413A1 CL2016002413A CL2016002413A CL2016002413A1 CL 2016002413 A1 CL2016002413 A1 CL 2016002413A1 CL 2016002413 A CL2016002413 A CL 2016002413A CL 2016002413 A CL2016002413 A CL 2016002413A CL 2016002413 A1 CL2016002413 A1 CL 2016002413A1
Authority
CL
Chile
Prior art keywords
virus
methods
antibodies against
against influenza
hemagglutinin antibodies
Prior art date
Application number
CL2016002413A
Other languages
English (en)
Inventor
Lee Swem
Min Xu
Mercedesz Balazs
Ning Chai
Nancy Chiang
Henry Chiu
Zhonghua Lin
Gerald R Nakamura
Hyunjoo Park
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CL2016002413A1 publication Critical patent/CL2016002413A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1018Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39583Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials not provided for elsewhere, e.g. haptens, coenzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51Complete heavy chain or Fd fragment, i.e. VH + CH1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515Complete light chain, i.e. VL + CL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CL2016002413A 2014-03-27 2016-09-26 Anticuerpos de hemaglutinina contra el virus de la influenza b y métodos de uso CL2016002413A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461971123P 2014-03-27 2014-03-27

Publications (1)

Publication Number Publication Date
CL2016002413A1 true CL2016002413A1 (es) 2017-06-23

Family

ID=52829396

Family Applications (2)

Application Number Title Priority Date Filing Date
CL2016002413A CL2016002413A1 (es) 2014-03-27 2016-09-26 Anticuerpos de hemaglutinina contra el virus de la influenza b y métodos de uso
CL2018002874A CL2018002874A1 (es) 2014-03-27 2018-10-09 Anticuerpos de hemaglutinina contra el virus de la influenza b y métodos de uso (divisional de solicitud n° 2413-2016).

Family Applications After (1)

Application Number Title Priority Date Filing Date
CL2018002874A CL2018002874A1 (es) 2014-03-27 2018-10-09 Anticuerpos de hemaglutinina contra el virus de la influenza b y métodos de uso (divisional de solicitud n° 2413-2016).

Country Status (20)

Country Link
US (2) US9745365B2 (es)
EP (1) EP3122771A1 (es)
JP (1) JP2017512471A (es)
KR (1) KR20160135830A (es)
CN (1) CN106132987A (es)
AR (1) AR099855A1 (es)
AU (1) AU2015235983A1 (es)
BR (1) BR112016022113A2 (es)
CA (1) CA2942820A1 (es)
CL (2) CL2016002413A1 (es)
CR (1) CR20160502A (es)
EA (1) EA201691945A1 (es)
IL (1) IL247870A0 (es)
MA (1) MA39803A (es)
MX (1) MX2016012530A (es)
PE (1) PE20161376A1 (es)
PH (1) PH12016501873A1 (es)
SG (1) SG11201607945UA (es)
TW (1) TW201620932A (es)
WO (1) WO2015148806A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7181091B2 (ja) 2016-05-10 2022-11-30 ジェネンテック, インコーポレイテッド ポリペプチドの組み換え産生中にトリスルフィド結合を減少させる方法
US20210002669A1 (en) 2017-12-22 2021-01-07 Genentech, Inc. Targeted integration of nucleic acids
MA51681A (fr) 2018-01-26 2021-05-05 Regeneron Pharma Anticorps humains contre l'hémagglutinine de la grippe
AR115318A1 (es) 2018-03-29 2020-12-23 Genentech Inc Modulación de la actividad lactogénica en células de mamífero
CN113631711A (zh) 2018-12-21 2021-11-09 豪夫迈·罗氏有限公司 核酸的靶向整合
RU2714246C1 (ru) * 2018-12-28 2020-02-13 Федеральное государственное бюджетное учреждение "Научно-исследовательский институт гриппа имени А.А. Смородинцева" Министерства здравоохранения Российской Федерации Моноклональные антитела, специфичные к различным штаммам вируса гриппа в
US11773156B2 (en) 2019-10-28 2023-10-03 Regeneron Pharmaceuticals, Inc. Anti-hemagglutinin antibodies and methods of use thereof
MX2022008901A (es) * 2020-01-24 2022-08-16 Regeneron Pharma Conjugados de proteinas-compuestos antivirales.
KR20220159426A (ko) 2020-03-26 2022-12-02 제넨테크, 인크. 감소된 숙주 세포 단백질을 보유하는 변형된 포유동물 세포
EP4172346A1 (en) 2020-06-24 2023-05-03 Genentech, Inc. Targeted integration of nucleic acids
US20220041672A1 (en) 2020-06-24 2022-02-10 Genentech, Inc. Apoptosis resistant cell lines
EP4204558A2 (en) 2020-08-28 2023-07-05 Genentech, Inc. Crispr/cas9 multiplex knockout of host cell proteins
CN114316032B (zh) * 2020-09-27 2022-12-27 东莞市朋志生物科技有限公司 抗乙型流感病毒的抗体、检测乙型流感病毒的试剂和试剂盒
JP2024514222A (ja) 2021-04-19 2024-03-28 ジェネンテック, インコーポレイテッド 改変された哺乳動物細胞
KR20240010469A (ko) 2021-05-21 2024-01-23 제넨테크, 인크. 관심 재조합 생성물의 생성을 위한 변형된 세포
WO2024104947A2 (en) 2022-11-14 2024-05-23 Janssen Vaccines & Prevention B.V. Influenza b virus vaccines and uses thereof
WO2024107879A1 (en) 2022-11-15 2024-05-23 Genentech, Inc. Combined transposon-mediated integration and targeted integration of nucleic acids into host cells

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2921928B1 (fr) 2007-10-08 2011-03-04 Sanofi Pasteur Anticorps monoclonaux specifiques de l'hemagglutinine du virus grippal
BE1018561A3 (fr) 2008-12-24 2011-03-01 Galactic Sa Procede de purification de l'acide lactique par cristallisation.
US8975378B2 (en) 2008-12-25 2015-03-10 Osaka University Human anti-human influenza virus antibody
DK2731967T3 (en) * 2011-07-14 2017-01-16 Janssen Vaccines & Prevention Bv HUMAN BINDING MOLECULES CAPABLE OF NEUTRALIZING INFLUENZA A VIRUS FROM PHYLOGENETIC GROUP 1 AND PHYLOGENETIC GROUP 2 AND INFLUENZA B VIRUS
WO2013114885A1 (en) 2012-01-31 2013-08-08 Osaka University Human monoclonal antibodies broadly protective against influenza b virus and methods of using the same
ES2664625T3 (es) * 2012-03-08 2018-04-20 Janssen Vaccines & Prevention B.V. Moléculas de unión humanas que pueden unirse a los virus de la influenza b y neutralizarlos, y sus usos

Also Published As

Publication number Publication date
US20150274812A1 (en) 2015-10-01
EP3122771A1 (en) 2017-02-01
US9745365B2 (en) 2017-08-29
CA2942820A1 (en) 2015-10-01
MA39803A (fr) 2017-02-01
US20170320937A1 (en) 2017-11-09
AR099855A1 (es) 2016-08-24
BR112016022113A2 (pt) 2017-10-31
CR20160502A (es) 2017-02-03
PE20161376A1 (es) 2016-12-26
JP2017512471A (ja) 2017-05-25
MX2016012530A (es) 2017-01-05
PH12016501873A1 (en) 2017-01-09
WO2015148806A1 (en) 2015-10-01
EA201691945A1 (ru) 2017-02-28
AU2015235983A1 (en) 2016-10-06
CL2018002874A1 (es) 2018-12-14
CN106132987A (zh) 2016-11-16
TW201620932A (zh) 2016-06-16
SG11201607945UA (en) 2016-10-28
KR20160135830A (ko) 2016-11-28
IL247870A0 (en) 2016-11-30

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