CL2015001568A1 - Métodos de detección multiplex de ácidos nucleicos - Google Patents

Métodos de detección multiplex de ácidos nucleicos

Info

Publication number
CL2015001568A1
CL2015001568A1 CL2015001568A CL2015001568A CL2015001568A1 CL 2015001568 A1 CL2015001568 A1 CL 2015001568A1 CL 2015001568 A CL2015001568 A CL 2015001568A CL 2015001568 A CL2015001568 A CL 2015001568A CL 2015001568 A1 CL2015001568 A1 CL 2015001568A1
Authority
CL
Chile
Prior art keywords
nucleic acid
detection methods
acid detection
multiplex nucleic
multiplex
Prior art date
Application number
CL2015001568A
Other languages
English (en)
Spanish (es)
Inventor
Eric Olivares
Jon Sorenson
Tom Landers
Original Assignee
Invitae Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Invitae Corp filed Critical Invitae Corp
Publication of CL2015001568A1 publication Critical patent/CL2015001568A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • C12Q1/6874Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2537/00Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/16Assays for determining copy number or wherein the copy number is of special importance

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CL2015001568A 2012-12-07 2015-06-05 Métodos de detección multiplex de ácidos nucleicos CL2015001568A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261734838P 2012-12-07 2012-12-07

Publications (1)

Publication Number Publication Date
CL2015001568A1 true CL2015001568A1 (es) 2016-08-26

Family

ID=50884061

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015001568A CL2015001568A1 (es) 2012-12-07 2015-06-05 Métodos de detección multiplex de ácidos nucleicos

Country Status (10)

Country Link
US (1) US9624533B2 (enExample)
EP (1) EP2929044B1 (enExample)
JP (1) JP6484177B2 (enExample)
CN (1) CN104995309B (enExample)
BR (1) BR112015013234B1 (enExample)
CA (1) CA2894381C (enExample)
CL (1) CL2015001568A1 (enExample)
HK (1) HK1216653A1 (enExample)
IL (1) IL239258B (enExample)
WO (1) WO2014089536A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3968023B1 (en) 2013-08-19 2025-10-08 Invitae Corporation Assays for single molecule detection and use thereof
WO2016070164A1 (en) * 2014-11-01 2016-05-06 Singular Bio, Inc. Assays for single molecule detection and use thereof
CN113528623A (zh) * 2015-02-18 2021-10-22 卓异生物公司 用于单分子检测的测定及其应用
CN107083427B (zh) * 2016-04-01 2021-07-30 广州市基准医疗有限责任公司 Dna连接酶介导的dna扩增技术
US11702702B2 (en) 2016-04-15 2023-07-18 Predicine, Inc. Systems and methods for detecting genetic alterations
US11174503B2 (en) 2016-09-21 2021-11-16 Predicine, Inc. Systems and methods for combined detection of genetic alterations
CA3048420C (en) * 2016-12-09 2025-05-20 Boreal Genomics Inc Linked ligation
WO2018127408A1 (en) * 2017-01-05 2018-07-12 Tervisetehnoloogiate Arenduskeskus As Quantifying dna sequences
US20180237853A1 (en) * 2017-02-19 2018-08-23 Yan Wang Methods, Compositions and Kits for Detection of Mutant Variants of Target Genes
CN107177693B (zh) * 2017-07-19 2020-11-06 中山大学 一种多倍pcr扩增方法
WO2019046768A1 (en) * 2017-08-31 2019-03-07 William Marsh Rice University SYMBOLIC SEQUENCING OF DNA AND RNA BY SEQUENCE CODING
CN110656159B (zh) * 2018-06-28 2024-01-09 深圳华大生命科学研究院 一种拷贝数变异的检测方法
EP3830828A4 (en) * 2018-07-27 2022-05-04 Myriad Women's Health, Inc. METHODS FOR DETECTING GENETIC VARIATIONS IN HIGHLY HOMOLOGOUS SEQUENCES BY INDEPENDENT ALIGNMENT AND PAIRING OF SEQUENCE READS
CN109402232A (zh) * 2018-10-23 2019-03-01 中国农业大学 一种用于检测的组合物及检测方法
US20220290242A1 (en) * 2018-11-05 2022-09-15 Centre Henri Becquerel Method for diagnosing a cancer and associated kit

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5508179A (en) 1994-03-18 1996-04-16 Bio-Rad Laboratories, Inc. Use of deoxyribose nicotinamide adenine dinucleotide to enhance the specificity of NAD+ -dependent ligation reactions
EP2369007B1 (en) * 1996-05-29 2015-07-29 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
US6544732B1 (en) 1999-05-20 2003-04-08 Illumina, Inc. Encoding and decoding of array sensors utilizing nanocrystals
GB0400584D0 (en) 2004-01-12 2004-02-11 Solexa Ltd Nucleic acid chacterisation
SE0401270D0 (sv) 2004-05-18 2004-05-18 Fredrik Dahl Method for amplifying specific nucleic acids in parallel
JP5237126B2 (ja) * 2006-03-01 2013-07-17 キージーン ナムローゼ フェンノートシャップ ライゲーションアッセイを用いてハイスループットシークエンスに基づき遺伝子関連配列を検出する方法
US8852864B2 (en) * 2008-01-17 2014-10-07 Sequenom Inc. Methods and compositions for the analysis of nucleic acids
CA2757300C (en) * 2009-04-01 2018-01-09 Dxterity Diagnostics Incorporated Chemical ligation dependent probe amplification (clpa)
WO2011071923A2 (en) * 2009-12-07 2011-06-16 Illumina, Inc. Multi-sample indexing for multiplex genotyping
WO2011091106A2 (en) * 2010-01-22 2011-07-28 The Regents Of The University Of California Compositions and methods for gene signature - based chemical screening
US20130225420A1 (en) * 2010-08-02 2013-08-29 The Regents Of The University Of California Molecular subtyping of oral squamous cell carcinoma to distinguish a subtype that is unlikely to metastasize
KR102085242B1 (ko) * 2011-05-17 2020-03-05 디엑스테리티 다이아그노스틱스 인코포레이티드 표적 핵산 검출을 위한 방법 및 조성물

Also Published As

Publication number Publication date
JP6484177B2 (ja) 2019-03-13
CA2894381A1 (en) 2014-06-12
US9624533B2 (en) 2017-04-18
BR112015013234A2 (pt) 2018-02-06
EP2929044A4 (en) 2016-07-13
CN104995309A (zh) 2015-10-21
US20140235470A1 (en) 2014-08-21
JP2016500257A (ja) 2016-01-12
EP2929044A1 (en) 2015-10-14
IL239258A0 (en) 2015-07-30
EP2929044B1 (en) 2019-02-06
CN104995309B (zh) 2020-12-08
WO2014089536A1 (en) 2014-06-12
HK1216653A1 (zh) 2016-11-25
BR112015013234B1 (pt) 2021-12-21
CA2894381C (en) 2021-01-12
IL239258B (en) 2019-12-31

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