CL2015001568A1 - Métodos de detección multiplex de ácidos nucleicos - Google Patents

Métodos de detección multiplex de ácidos nucleicos

Info

Publication number
CL2015001568A1
CL2015001568A1 CL2015001568A CL2015001568A CL2015001568A1 CL 2015001568 A1 CL2015001568 A1 CL 2015001568A1 CL 2015001568 A CL2015001568 A CL 2015001568A CL 2015001568 A CL2015001568 A CL 2015001568A CL 2015001568 A1 CL2015001568 A1 CL 2015001568A1
Authority
CL
Chile
Prior art keywords
nucleic acid
detection methods
acid detection
multiplex nucleic
multiplex
Prior art date
Application number
CL2015001568A
Other languages
English (en)
Spanish (es)
Inventor
Eric Olivares
Jon Sorenson
Tom Landers
Original Assignee
Invitae Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Invitae Corp filed Critical Invitae Corp
Publication of CL2015001568A1 publication Critical patent/CL2015001568A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/16—Assays for determining copy number or wherein the copy number is of special importance

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CL2015001568A 2012-12-07 2015-06-05 Métodos de detección multiplex de ácidos nucleicos CL2015001568A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261734838P 2012-12-07 2012-12-07

Publications (1)

Publication Number Publication Date
CL2015001568A1 true CL2015001568A1 (es) 2016-08-26

Family

ID=50884061

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015001568A CL2015001568A1 (es) 2012-12-07 2015-06-05 Métodos de detección multiplex de ácidos nucleicos

Country Status (10)

Country Link
US (1) US9624533B2 (enExample)
EP (1) EP2929044B1 (enExample)
JP (1) JP6484177B2 (enExample)
CN (1) CN104995309B (enExample)
BR (1) BR112015013234B1 (enExample)
CA (1) CA2894381C (enExample)
CL (1) CL2015001568A1 (enExample)
HK (1) HK1216653A1 (enExample)
IL (1) IL239258B (enExample)
WO (1) WO2014089536A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105659091A (zh) 2013-08-19 2016-06-08 卓异生物公司 用于单分子检测的测定及其应用
US20180023138A1 (en) * 2014-11-01 2018-01-25 Singular Bio, Inc. Assays for Single Molecule Detection and Use Thereof
WO2016134191A1 (en) 2015-02-18 2016-08-25 Singular Bio, Inc. Assays for single molecule detection and use thereof
CN107083427B (zh) * 2016-04-01 2021-07-30 广州市基准医疗有限责任公司 Dna连接酶介导的dna扩增技术
WO2018057820A1 (en) 2016-09-21 2018-03-29 Predicine, Inc. Systems and methods for combined detection of genetic alterations
WO2017181161A1 (en) * 2016-04-15 2017-10-19 Predicine, Inc. Systems and methods for detecting genetic alterations
JP7048609B2 (ja) * 2016-12-09 2022-04-05 ボリアル ジェノミクス, インコーポレイテッド 連結型ライゲーション
EP3565906B1 (en) * 2017-01-05 2021-01-27 Tervisetehnoloogiate Arenduskeskus AS Quantifying dna sequences
US20180237853A1 (en) * 2017-02-19 2018-08-23 Yan Wang Methods, Compositions and Kits for Detection of Mutant Variants of Target Genes
CN107177693B (zh) * 2017-07-19 2020-11-06 中山大学 一种多倍pcr扩增方法
WO2019046768A1 (en) * 2017-08-31 2019-03-07 William Marsh Rice University SYMBOLIC SEQUENCING OF DNA AND RNA BY SEQUENCE CODING
CN110656159B (zh) * 2018-06-28 2024-01-09 深圳华大生命科学研究院 一种拷贝数变异的检测方法
EP3830828A4 (en) * 2018-07-27 2022-05-04 Myriad Women's Health, Inc. METHODS FOR DETECTING GENETIC VARIATIONS IN HIGHLY HOMOLOGOUS SEQUENCES BY INDEPENDENT ALIGNMENT AND PAIRING OF SEQUENCE READS
CN109402232A (zh) * 2018-10-23 2019-03-01 中国农业大学 一种用于检测的组合物及检测方法
US20220290242A1 (en) * 2018-11-05 2022-09-15 Centre Henri Becquerel Method for diagnosing a cancer and associated kit
CN115786455B (zh) * 2022-07-12 2026-06-12 江阴检汇生物科技有限公司 一种基于mlpa-ngs方法用于司法鉴定的snp位点检测组合物及其应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5508179A (en) 1994-03-18 1996-04-16 Bio-Rad Laboratories, Inc. Use of deoxyribose nicotinamide adenine dinucleotide to enhance the specificity of NAD+ -dependent ligation reactions
AU730633B2 (en) * 1996-05-29 2001-03-08 Phillip Belgrader Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
US6544732B1 (en) 1999-05-20 2003-04-08 Illumina, Inc. Encoding and decoding of array sensors utilizing nanocrystals
GB0400584D0 (en) 2004-01-12 2004-02-11 Solexa Ltd Nucleic acid chacterisation
SE0401270D0 (sv) 2004-05-18 2004-05-18 Fredrik Dahl Method for amplifying specific nucleic acids in parallel
DK1991698T3 (en) * 2006-03-01 2014-03-10 Keygene Nv "High-throughput" -sekvensbaseret detection of SNPs using ligeringsassays
WO2009092035A2 (en) * 2008-01-17 2009-07-23 Sequenom, Inc. Methods and compositions for the analysis of biological molecules
WO2010114599A1 (en) * 2009-04-01 2010-10-07 Dx Terity Diagnostics Inc. Chemical ligation dependent probe amplification (clpa)
WO2011071923A2 (en) * 2009-12-07 2011-06-16 Illumina, Inc. Multi-sample indexing for multiplex genotyping
EP2526207A4 (en) 2010-01-22 2013-10-09 Univ California COMPOSITIONS AND METHODS FOR CHEMICAL SCREENING AT SIGNATURE BASE
US10066257B2 (en) * 2010-03-29 2018-09-04 Dxterity Diagnostics Incorporated Methods and compositions for detecting target nucleic acids
WO2012018397A2 (en) * 2010-08-02 2012-02-09 The Regents Of The University Of California Molecular subtyping of oral squamous cell carcinoma to distinguish a subtype that is unlikely to metastasize

Also Published As

Publication number Publication date
IL239258B (en) 2019-12-31
JP6484177B2 (ja) 2019-03-13
BR112015013234A2 (pt) 2018-02-06
WO2014089536A1 (en) 2014-06-12
BR112015013234B1 (pt) 2021-12-21
CN104995309B (zh) 2020-12-08
EP2929044A1 (en) 2015-10-14
CN104995309A (zh) 2015-10-21
HK1216653A1 (zh) 2016-11-25
CA2894381C (en) 2021-01-12
EP2929044A4 (en) 2016-07-13
US20140235470A1 (en) 2014-08-21
CA2894381A1 (en) 2014-06-12
US9624533B2 (en) 2017-04-18
JP2016500257A (ja) 2016-01-12
EP2929044B1 (en) 2019-02-06
IL239258A0 (en) 2015-07-30

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